PH23082A - 2-descarboxy-2-alkanoyl or 2-hydroxyalkyl pgi2 derivatives and pharmaceutical composition containing it - Google Patents
2-descarboxy-2-alkanoyl or 2-hydroxyalkyl pgi2 derivatives and pharmaceutical composition containing itInfo
- Publication number
- PH23082A PH23082A PH31831A PH31831A PH23082A PH 23082 A PH23082 A PH 23082A PH 31831 A PH31831 A PH 31831A PH 31831 A PH31831 A PH 31831A PH 23082 A PH23082 A PH 23082A
- Authority
- PH
- Philippines
- Prior art keywords
- group
- alkyl
- descarboxy
- alkanoyl
- hydroxyalkyl
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 125000002947 alkylene group Chemical group 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 2
- 125000000623 heterocyclic group Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- -1 hydroxymethylene group Chemical group 0.000 abstract 2
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000001120 cytoprotective effect Effects 0.000 abstract 1
- 125000001153 fluoro group Chemical group F* 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical group 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 125000000468 ketone group Chemical group 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/005—Analogues or derivatives having the five membered ring replaced by other rings
- C07C405/0075—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system
- C07C405/0083—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system which is only ortho or peri condensed, e.g. carbacyclins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Ink Jet Recording Methods And Recording Media Thereof (AREA)
- Drawers Of Furniture (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19843405181 DE3405181A1 (de) | 1984-02-10 | 1984-02-10 | Neue carbacycline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PH23082A true PH23082A (en) | 1989-04-10 |
Family
ID=6227657
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PH31831A PH23082A (en) | 1984-02-10 | 1985-02-08 | 2-descarboxy-2-alkanoyl or 2-hydroxyalkyl pgi2 derivatives and pharmaceutical composition containing it |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US4721729A (fr) |
| EP (1) | EP0153274B1 (fr) |
| JP (1) | JPS60188336A (fr) |
| AT (1) | ATE52770T1 (fr) |
| AU (1) | AU567205B2 (fr) |
| CS (1) | CS252481B2 (fr) |
| DD (1) | DD233997A5 (fr) |
| DE (2) | DE3405181A1 (fr) |
| DK (1) | DK56285A (fr) |
| ES (1) | ES540264A0 (fr) |
| FI (1) | FI850519L (fr) |
| GR (1) | GR850351B (fr) |
| HU (1) | HU192316B (fr) |
| IE (1) | IE850305L (fr) |
| IL (1) | IL74280A0 (fr) |
| NO (1) | NO160846C (fr) |
| NZ (1) | NZ211048A (fr) |
| PH (1) | PH23082A (fr) |
| ZA (1) | ZA85985B (fr) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3608088C2 (de) * | 1986-03-07 | 1995-11-16 | Schering Ag | Pharmazeutische Präparate, enthaltend Cyclodextrinclathrate von Carbacyclinderivaten |
| DE3638761A1 (de) * | 1986-11-13 | 1988-05-26 | Schering Ag | Verbesserte ketoreduktion von carbacyclinzwischenprodukten |
| ATE386531T1 (de) * | 1997-02-28 | 2008-03-15 | Nycomed Gmbh | Synergistische kombination von pde-hemmern und adenylatcyclase-agonisten bzw. guanylcyclyse- agonisten |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL7605381A (nl) * | 1975-05-26 | 1976-11-30 | Schering Ag | Werkwijze voor het bereiden van prostaanderi- vaten en werkwijze voor het bereiden van een geneesmiddel met prostaglandinewerking. |
| GB2038333B (en) * | 1978-01-26 | 1982-10-06 | Erba Farmitalia | 12 -formyl- (20 12)octanor-9-deoxy-9 -methylene pgi derivatives |
| US4123463A (en) * | 1978-03-21 | 1978-10-31 | The Upjohn Company | 2-Decarboxy-2-alkylketone prostaglandins |
| DE3121155A1 (de) * | 1981-05-22 | 1982-12-09 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Neue carbacycline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| DE3225287A1 (de) * | 1982-07-02 | 1984-01-05 | Schering AG, 1000 Berlin und 4709 Bergkamen | Neue carbacyclinamide, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| DE3226550A1 (de) * | 1982-07-13 | 1984-01-19 | Schering AG, 1000 Berlin und 4709 Bergkamen | Neue carbacycline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
-
1984
- 1984-02-10 DE DE19843405181 patent/DE3405181A1/de not_active Withdrawn
-
1985
- 1985-02-05 NZ NZ211048A patent/NZ211048A/xx unknown
- 1985-02-06 DD DD85273085A patent/DD233997A5/de unknown
- 1985-02-07 FI FI850519A patent/FI850519L/fi not_active Application Discontinuation
- 1985-02-07 AT AT85730022T patent/ATE52770T1/de not_active IP Right Cessation
- 1985-02-07 EP EP85730022A patent/EP0153274B1/fr not_active Expired - Lifetime
- 1985-02-07 DE DE8585730022T patent/DE3577702D1/de not_active Expired - Lifetime
- 1985-02-07 DK DK56285A patent/DK56285A/da not_active Application Discontinuation
- 1985-02-08 ES ES540264A patent/ES540264A0/es active Granted
- 1985-02-08 IL IL74280A patent/IL74280A0/xx unknown
- 1985-02-08 IE IE850305A patent/IE850305L/xx unknown
- 1985-02-08 PH PH31831A patent/PH23082A/en unknown
- 1985-02-08 US US06/702,092 patent/US4721729A/en not_active Expired - Fee Related
- 1985-02-08 NO NO850486A patent/NO160846C/no unknown
- 1985-02-08 GR GR850351A patent/GR850351B/el unknown
- 1985-02-08 JP JP60022102A patent/JPS60188336A/ja active Pending
- 1985-02-08 HU HU85497A patent/HU192316B/hu not_active IP Right Cessation
- 1985-02-08 ZA ZA85985A patent/ZA85985B/xx unknown
- 1985-02-11 AU AU38614/85A patent/AU567205B2/en not_active Ceased
- 1985-02-11 CS CS85951A patent/CS252481B2/cs unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US4721729A (en) | 1988-01-26 |
| ES8601835A1 (es) | 1985-12-01 |
| CS252481B2 (en) | 1987-09-17 |
| NO160846B (no) | 1989-02-27 |
| ATE52770T1 (de) | 1990-06-15 |
| CS95185A2 (en) | 1987-01-15 |
| HUT36814A (en) | 1985-10-28 |
| DK56285D0 (da) | 1985-02-07 |
| DK56285A (da) | 1985-08-11 |
| GR850351B (fr) | 1985-06-05 |
| NZ211048A (en) | 1988-09-29 |
| IE850305L (en) | 1985-08-10 |
| JPS60188336A (ja) | 1985-09-25 |
| NO160846C (no) | 1989-06-07 |
| ZA85985B (en) | 1985-09-25 |
| FI850519L (fi) | 1985-08-11 |
| EP0153274A1 (fr) | 1985-08-28 |
| AU3861485A (en) | 1985-08-15 |
| DE3405181A1 (de) | 1985-08-22 |
| NO850486L (no) | 1985-08-12 |
| DD233997A5 (de) | 1986-03-19 |
| EP0153274B1 (fr) | 1990-05-16 |
| ES540264A0 (es) | 1985-12-01 |
| HU192316B (en) | 1987-05-28 |
| AU567205B2 (en) | 1987-11-12 |
| FI850519A0 (fi) | 1985-02-07 |
| IL74280A0 (en) | 1985-05-31 |
| DE3577702D1 (de) | 1990-06-21 |
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