PH18383A - Compositions for treating glaucoma - Google Patents
Compositions for treating glaucomaInfo
- Publication number
- PH18383A PH18383A PH27417A PH27417A PH18383A PH 18383 A PH18383 A PH 18383A PH 27417 A PH27417 A PH 27417A PH 27417 A PH27417 A PH 27417A PH 18383 A PH18383 A PH 18383A
- Authority
- PH
- Philippines
- Prior art keywords
- mammal
- compounds
- action
- treatment
- intraocular pressure
- Prior art date
Links
- 208000010412 Glaucoma Diseases 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 241000124008 Mammalia Species 0.000 abstract 2
- 230000004410 intraocular pressure Effects 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 239000012530 fluid Substances 0.000 abstract 1
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000001839 systemic circulation Effects 0.000 abstract 1
- 230000009885 systemic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
- A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
- A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
- A61K31/245—Amino benzoic acid types, e.g. procaine, novocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C219/02—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C219/04—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C219/14—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the hydroxy groups esterified by a carboxylic acid having the esterifying carboxyl group bound to a carbon atom of a six-membered aromatic ring
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Emergency Medicine (AREA)
- Ophthalmology & Optometry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/276,657 US4402974A (en) | 1981-06-23 | 1981-06-23 | Method for treating glaucoma by the topical administration of selectively metabolized beta-blocking agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PH18383A true PH18383A (en) | 1985-06-19 |
Family
ID=23057572
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PH27417A PH18383A (en) | 1981-06-23 | 1982-06-14 | Compositions for treating glaucoma |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US4402974A (el) |
| EP (1) | EP0081580B1 (el) |
| JP (1) | JPS58500997A (el) |
| AT (1) | AT384017B (el) |
| AU (1) | AU559541B2 (el) |
| CA (1) | CA1272733C (el) |
| CH (1) | CH655497B (el) |
| ES (1) | ES513386A0 (el) |
| GB (2) | GB2112785B (el) |
| GR (1) | GR76848B (el) |
| IL (1) | IL66069A0 (el) |
| IT (1) | IT1156057B (el) |
| NL (1) | NL8220251A (el) |
| NZ (1) | NZ200971A (el) |
| PH (1) | PH18383A (el) |
| SE (1) | SE464300B (el) |
| WO (1) | WO1983000043A1 (el) |
| ZA (1) | ZA824339B (el) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1582884A (en) * | 1977-05-19 | 1981-01-14 | Beecham Group Ltd | Clavulanic acid derivatives their preparation and use |
| ZA804670B (en) * | 1979-08-03 | 1981-07-29 | Beecham Group Ltd | Derivatives of clavulanic acid, a process for their preparation and their use |
| US4604481A (en) * | 1980-11-28 | 1986-08-05 | American Hospital Supply Corporation | Compounds for treatment or prophylaxis of cardiac disorders |
| EP0053893B1 (en) * | 1980-12-09 | 1985-03-20 | Beecham Group Plc | Derivatives of clavulanic acid, their preparation and their use |
| NZ199200A (en) * | 1980-12-23 | 1984-07-31 | Beecham Group Ltd | Clavulanic acid derivatives and pharmaceutical compositions |
| US4579867A (en) * | 1984-04-09 | 1986-04-01 | American Hospital Supply Corporation | Stable pharmaceutical compositions of short-acting β-adrenergic receptor blocking agents |
| CA1334168C (en) * | 1988-04-26 | 1995-01-31 | Louis M. De Santis | Antiglaucoma compositions containing combinations of .alpha.-2 agonists and .beta. blockers |
| US4897417A (en) * | 1988-12-15 | 1990-01-30 | E. I. Du Pont De Nemours & Co. | Prodrugs of 3,4-hydroxy benzoyloxypropanolamines |
| US4966914A (en) * | 1988-12-15 | 1990-10-30 | E. I. Du Pont De Nemours And Company | Oculoselective beta-blockers as antiglaucoma agents |
| CH679856A5 (el) * | 1990-07-04 | 1992-04-30 | Lonza Ag | |
| US5629345A (en) * | 1993-07-23 | 1997-05-13 | Vide Pharmaceuticals | Methods and compositions for ATP-sensitive K+ channel inhibition for lowering intraocular pressure |
| US5965620A (en) * | 1993-07-23 | 1999-10-12 | Vide Pharmaceuticals | Methods and compositions for ATP-sensitive K+ channel inhibition for lowering intraocular pressure |
| US5543083A (en) * | 1994-07-26 | 1996-08-06 | The Procter & Gamble Company | Fatty amine derivatives of butylated hydroxy toluene for the protection of surfaces from physical and chemical degradation |
| US5536749A (en) * | 1994-10-13 | 1996-07-16 | Sl Pharmaceuticals, Inc. | Method for attenuation of sympathetic nervous system activity or onset of migraine by selectively metabolized beta-blocking agents |
| US6197817B1 (en) | 1999-01-22 | 2001-03-06 | Selectus Pharmaceuticals, Inc. | Phenylpropionic acids and esters: compounds and methods for inducing beta-blockade for the treatment of cardiac disorders |
| US7209743B2 (en) * | 2004-04-22 | 2007-04-24 | Telefonaktiebolaget Lm Ericsson (Publ) | Base station system and method for compensating traffic channel signal strength measurements in a cellular radio telecommunication network |
| US20070254950A1 (en) * | 2004-05-25 | 2007-11-01 | Othera Pharmaceuticals, Inc. | Oculoselective Drugs and Prodrugs |
| CA2576279A1 (en) * | 2004-11-08 | 2006-05-18 | Nitromed, Inc. | Nitrosated and nitrosylated compounds, compositions and methods for the treatment of ophthalmic disorders |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL75127C (el) * | 1943-10-05 | |||
| FR1047364A (fr) * | 1950-12-28 | 1953-12-14 | Hoechst Ag | Esters d'acides alcoylamino-benzoïques, sels d'acides minéraux de ces esters et procédé de préparation de ces corps |
| NL300886A (el) * | 1962-11-23 | |||
| US3959351A (en) * | 1972-07-24 | 1976-05-25 | Research Corporation | Haloalkylbenzoyl esters of di-lower alkylamino alkanols and quaternary lower alkyl salts thereof |
| US4195085A (en) * | 1975-09-26 | 1980-03-25 | Merck & Co., Inc. | Compositions and methods for treating glaucoma by the topical administration of t-butylamino-3-(4-morpholino-1,2,5-thiadiazol-3-yloxy-2-phopanol hydrogen maleate |
| DE2752659A1 (de) | 1976-12-07 | 1978-06-08 | Sandoz Ag | Neue tetralinderivate, ihre herstellung und verwendung |
| US4127674A (en) * | 1977-03-21 | 1978-11-28 | Allergan Pharmaceuticals, Inc. | Method of treatment for glaucoma |
| EP0003664B1 (en) * | 1978-02-08 | 1982-02-17 | Imperial Chemical Industries Plc | Alkanolamine derivatives, process for their preparation and pharmaceutical compositions containing them |
| US4405642A (en) * | 1980-11-28 | 1983-09-20 | American Hospital Supply Corporation | Method for treatment or prophylaxis of cardiac disorders |
-
1981
- 1981-06-23 US US06/276,657 patent/US4402974A/en not_active Expired - Fee Related
-
1982
- 1982-06-14 PH PH27417A patent/PH18383A/en unknown
- 1982-06-14 CA CA 405106 patent/CA1272733C/xx not_active Expired - Lifetime
- 1982-06-15 NZ NZ200971A patent/NZ200971A/en unknown
- 1982-06-16 IL IL66069A patent/IL66069A0/xx not_active IP Right Cessation
- 1982-06-18 ZA ZA824339A patent/ZA824339B/xx unknown
- 1982-06-18 GR GR68484A patent/GR76848B/el unknown
- 1982-06-22 IT IT67795/82A patent/IT1156057B/it active
- 1982-06-23 JP JP57502294A patent/JPS58500997A/ja active Granted
- 1982-06-23 AU AU87375/82A patent/AU559541B2/en not_active Ceased
- 1982-06-23 WO PCT/US1982/000848 patent/WO1983000043A1/en active IP Right Grant
- 1982-06-23 CH CH110483A patent/CH655497B/de unknown
- 1982-06-23 EP EP82902332A patent/EP0081580B1/en not_active Expired
- 1982-06-23 AT AT0903482A patent/AT384017B/de not_active IP Right Cessation
- 1982-06-23 NL NL8220251A patent/NL8220251A/nl unknown
- 1982-06-23 ES ES513386A patent/ES513386A0/es active Granted
- 1982-06-23 GB GB08303060A patent/GB2112785B/en not_active Expired
-
1983
- 1983-02-18 SE SE8300912A patent/SE464300B/sv not_active IP Right Cessation
-
1984
- 1984-08-30 GB GB08421939A patent/GB2145721B/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| WO1983000043A1 (en) | 1983-01-06 |
| US4402974A (en) | 1983-09-06 |
| EP0081580B1 (en) | 1987-04-22 |
| JPS58500997A (ja) | 1983-06-23 |
| IT1156057B (it) | 1987-01-28 |
| GB2145721A (en) | 1985-04-03 |
| ES8401927A1 (es) | 1984-01-01 |
| AU8737582A (en) | 1983-01-18 |
| GB8303060D0 (en) | 1983-03-09 |
| ES513386A0 (es) | 1984-01-01 |
| NL8220251A (nl) | 1983-05-02 |
| EP0081580A1 (en) | 1983-06-22 |
| ATA903482A (de) | 1987-02-15 |
| IT8267795A0 (it) | 1982-06-22 |
| GB2112785A (en) | 1983-07-27 |
| CA1220716A (en) | 1987-04-21 |
| CH655497B (el) | 1986-04-30 |
| JPH0428696B2 (el) | 1992-05-15 |
| IL66069A0 (en) | 1982-09-30 |
| SE464300B (sv) | 1991-04-08 |
| GB2145721B (en) | 1986-02-19 |
| NZ200971A (en) | 1985-12-13 |
| SE8300912D0 (sv) | 1983-02-18 |
| AT384017B (de) | 1987-09-25 |
| EP0081580A4 (en) | 1983-12-01 |
| GB8421939D0 (en) | 1984-10-03 |
| SE8300912L (sv) | 1983-02-18 |
| GR76848B (el) | 1984-09-04 |
| ZA824339B (en) | 1983-04-27 |
| GB2112785B (en) | 1985-06-05 |
| AU559541B2 (en) | 1987-03-12 |
| CA1272733C (en) | 1990-08-14 |
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