PH17503A - A process for the preparation of 1,3,7-trialkyl-xanthines and 1-isopropyl-and 1-isobutyl-3,7-dimethyl xanteines as medicaments - Google Patents

A process for the preparation of 1,3,7-trialkyl-xanthines and 1-isopropyl-and 1-isobutyl-3,7-dimethyl xanteines as medicaments

Info

Publication number
PH17503A
PH17503A PH24053A PH24053A PH17503A PH 17503 A PH17503 A PH 17503A PH 24053 A PH24053 A PH 24053A PH 24053 A PH24053 A PH 24053A PH 17503 A PH17503 A PH 17503A
Authority
PH
Philippines
Prior art keywords
xanteines
xanthines
trialkyl
medicaments
isobutyl
Prior art date
Application number
PH24053A
Other languages
English (en)
Inventor
Georges Philippossian
Marc Enslen
Original Assignee
Nestle Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nestle Sa filed Critical Nestle Sa
Publication of PH17503A publication Critical patent/PH17503A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C07D473/10—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 3 and 7, e.g. theobromine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Anesthesiology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PH24053A 1979-05-22 1980-05-21 A process for the preparation of 1,3,7-trialkyl-xanthines and 1-isopropyl-and 1-isobutyl-3,7-dimethyl xanteines as medicaments PH17503A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH4780/79A CH654008A5 (fr) 1979-05-22 1979-05-22 Procede de preparation de 1,3,7-trialkylxanthines.

Publications (1)

Publication Number Publication Date
PH17503A true PH17503A (en) 1984-09-07

Family

ID=4282410

Family Applications (1)

Application Number Title Priority Date Filing Date
PH24053A PH17503A (en) 1979-05-22 1980-05-21 A process for the preparation of 1,3,7-trialkyl-xanthines and 1-isopropyl-and 1-isobutyl-3,7-dimethyl xanteines as medicaments

Country Status (13)

Country Link
US (2) US4299833A (es)
EP (1) EP0019165B1 (es)
JP (2) JPS55154973A (es)
CH (1) CH654008A5 (es)
DE (1) DE3070919D1 (es)
ES (1) ES491683A0 (es)
GB (1) GB2052480B (es)
HK (1) HK13984A (es)
HU (1) HU184280B (es)
IL (1) IL60025A (es)
MY (1) MY8400259A (es)
PH (1) PH17503A (es)
SG (1) SG29483G (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH643260A5 (fr) * 1980-05-02 1984-05-30 Nestle Sa 1-allyl-3-butyl-8-methylxanthine, procede de preparation et utilisation dans un medicament.
IT1200944B (it) * 1982-08-10 1989-01-27 Malesci Sas Derivati xantinici,procedimento per la loro preparazione,composizione farmaceutiche che il contengono e loro impiego terapeutico
EP0262344B1 (de) * 1986-08-07 1996-03-27 MEDICEChem.-Pharm. Fabrik Pütter GmbH & Co. KG N-alkylierte quartäre stickstoffhaltige Heterozyklen, Verfahren zu deren Herstellung und deren Verwendung in Arzneimitteln
GB8906792D0 (en) * 1989-03-23 1989-05-10 Beecham Wuelfing Gmbh & Co Kg Treatment and compounds
NZ240644A (en) * 1990-11-21 1994-08-26 Smithkline Beecham Corp Use of xanthine derivatives to inhibit the production of tumour necrosis factor (tnf)
IT1258944B (it) * 1992-06-22 1996-03-08 Emilio Toja Derivati 7-neopentil xantinici, loro preparazione e composizioni farmaceutiche che li contengono
TW225535B (es) * 1992-11-10 1994-06-21 Hoechst Ag
EP1893614B1 (en) * 2005-06-21 2013-05-22 The University Court of the University of Dundee Inhibitor compounds
WO2008107436A1 (en) * 2007-03-06 2008-09-12 Novartis Ag Bicyclic organic compounds suitable for the treatment of inflammatory or allergic conditions
CN101220032B (zh) * 2007-12-14 2010-06-02 百利高贸易（上海）有限公司 3_甲基黄嘌呤二钠盐甲化制备可可碱的新方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH4780A (fr) 1892-04-05 1892-07-30 Emile Bauer Nouveau système de machine à détente
US631757A (en) * 1898-02-18 1899-08-22 Boehringer & Soehne Xanthin derivative and process of making same.
US631760A (en) * 1898-03-04 1899-08-22 Boehringer & Soehne Alkylized xanthin and process of making same.
US2523496A (en) * 1948-10-21 1950-09-26 Kenneth N Campbell Method of preparing xanthine and methylated xanthines
GB706424A (en) * 1950-05-17 1954-03-31 Hoechst Ag Manufacture of xanthine and its alkyl derivatives
US3740433A (en) * 1971-10-01 1973-06-19 Squibb & Sons Inc Anti-anxiety composition and method of use
DE2714953C2 (de) * 1977-04-02 1986-09-25 Hoechst Ag, 6230 Frankfurt Arzneimittel

Also Published As

Publication number Publication date
EP0019165B1 (fr) 1985-07-31
GB2052480B (en) 1983-03-16
EP0019165A1 (fr) 1980-11-26
SG29483G (en) 1985-01-11
GB2052480A (en) 1981-01-28
JPS55154973A (en) 1980-12-02
IL60025A0 (en) 1980-07-31
HU184280B (en) 1984-07-30
US4299833A (en) 1981-11-10
JPH0210835B2 (es) 1990-03-09
US4450163A (en) 1984-05-22
MY8400259A (en) 1984-12-31
CH654008A5 (fr) 1986-01-31
IL60025A (en) 1984-10-31
DE3070919D1 (en) 1985-09-05
HK13984A (en) 1984-02-24
ES8104290A1 (es) 1981-04-16
JPH01199972A (ja) 1989-08-11
ES491683A0 (es) 1981-04-16

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