ES8104290A1 - Procedimiento para la preparacion de 1,3,7-trialquilxantinas - Google Patents

Procedimiento para la preparacion de 1,3,7-trialquilxantinas

Info

Publication number
ES8104290A1
ES8104290A1 ES491683A ES491683A ES8104290A1 ES 8104290 A1 ES8104290 A1 ES 8104290A1 ES 491683 A ES491683 A ES 491683A ES 491683 A ES491683 A ES 491683A ES 8104290 A1 ES8104290 A1 ES 8104290A1
Authority
ES
Spain
Prior art keywords
trialkylxanthines
preparing
medicaments
isobutyl
isopropyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES491683A
Other languages
English (en)
Other versions
ES491683A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Societe des Produits Nestle SA
Nestle SA
Original Assignee
Societe des Produits Nestle SA
Nestle SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Societe des Produits Nestle SA, Nestle SA filed Critical Societe des Produits Nestle SA
Publication of ES8104290A1 publication Critical patent/ES8104290A1/es
Publication of ES491683A0 publication Critical patent/ES491683A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C07D473/10—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 3 and 7, e.g. theobromine

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE 1,3,7-TRIALQUILXANTINAS, QUE CONSTITUYEN LA MATERIA ACTIVA EN LA OBTENCION DE COMPOSICIONES FARMACEUTICAS DE EFECTO NEUROLEPTICO. CONSISTE EN HACER REACCIONAR UNA XANTINA CON UN AGENTE ALQUILANTE R-X EN PRESENCIA DE UN CATALIZADOR DE TRANSFERENCIA DE FASE. LAS XANTINAS QUE SE EMPLEAN SON XANTINAS C-ALQUILADAS Y PARCIALMENTE SUSTITUIDAS. SE OBTIENE DE ESTA FORMA 1-ISOPROPIL-3,7-DIMETILXANTINA, O 1-ISOBUTIL-3,7-DIMETILXANTINA.
ES491683A 1979-05-22 1980-05-21 Procedimiento para la preparacion de 1,3,7-trialquilxantinas Granted ES491683A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH4780/79A CH654008A5 (fr) 1979-05-22 1979-05-22 Procede de preparation de 1,3,7-trialkylxanthines.

Publications (2)

Publication Number Publication Date
ES8104290A1 true ES8104290A1 (es) 1981-04-16
ES491683A0 ES491683A0 (es) 1981-04-16

Family

ID=4282410

Family Applications (1)

Application Number Title Priority Date Filing Date
ES491683A Granted ES491683A0 (es) 1979-05-22 1980-05-21 Procedimiento para la preparacion de 1,3,7-trialquilxantinas

Country Status (13)

Country Link
US (2) US4299833A (es)
EP (1) EP0019165B1 (es)
JP (2) JPS55154973A (es)
CH (1) CH654008A5 (es)
DE (1) DE3070919D1 (es)
ES (1) ES491683A0 (es)
GB (1) GB2052480B (es)
HK (1) HK13984A (es)
HU (1) HU184280B (es)
IL (1) IL60025A (es)
MY (1) MY8400259A (es)
PH (1) PH17503A (es)
SG (1) SG29483G (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH643260A5 (fr) * 1980-05-02 1984-05-30 Nestle Sa 1-allyl-3-butyl-8-methylxanthine, procede de preparation et utilisation dans un medicament.
IT1200944B (it) * 1982-08-10 1989-01-27 Malesci Sas Derivati xantinici,procedimento per la loro preparazione,composizione farmaceutiche che il contengono e loro impiego terapeutico
AU613582B2 (en) * 1986-08-07 1991-08-08 Medice Chem.-Pharm. Fabrik Putter Gmbh & Co. Kg N-alkylated quaternary nitrogen-containing 6-membered heterocycles
GB8906792D0 (en) 1989-03-23 1989-05-10 Beecham Wuelfing Gmbh & Co Kg Treatment and compounds
NZ240644A (en) * 1990-11-21 1994-08-26 Smithkline Beecham Corp Use of xanthine derivatives to inhibit the production of tumour necrosis factor (tnf)
IT1258944B (it) * 1992-06-22 1996-03-08 Emilio Toja Derivati 7-neopentil xantinici, loro preparazione e composizioni farmaceutiche che li contengono
TW225535B (es) * 1992-11-10 1994-06-21 Hoechst Ag
US8207175B2 (en) * 2005-06-21 2012-06-26 University Court Of The University Of Dundee Inhibitor compounds
EA200901167A1 (ru) * 2007-03-06 2010-04-30 Новартис Аг Бициклические органические соединения, пригодные для лечения воспалительных и аллергических состояний
CN101220032B (zh) * 2007-12-14 2010-06-02 百利高贸易（上海）有限公司 3_甲基黄嘌呤二钠盐甲化制备可可碱的新方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH4780A (fr) 1892-04-05 1892-07-30 Emile Bauer Nouveau système de machine à détente
US631757A (en) * 1898-02-18 1899-08-22 Boehringer & Soehne Xanthin derivative and process of making same.
US631760A (en) * 1898-03-04 1899-08-22 Boehringer & Soehne Alkylized xanthin and process of making same.
US2523496A (en) * 1948-10-21 1950-09-26 Kenneth N Campbell Method of preparing xanthine and methylated xanthines
GB706424A (en) * 1950-05-17 1954-03-31 Hoechst Ag Manufacture of xanthine and its alkyl derivatives
US3740433A (en) * 1971-10-01 1973-06-19 Squibb & Sons Inc Anti-anxiety composition and method of use
DE2714953C2 (de) * 1977-04-02 1986-09-25 Hoechst Ag, 6230 Frankfurt Arzneimittel

Also Published As

Publication number Publication date
PH17503A (en) 1984-09-07
HK13984A (en) 1984-02-24
US4450163A (en) 1984-05-22
EP0019165B1 (fr) 1985-07-31
US4299833A (en) 1981-11-10
EP0019165A1 (fr) 1980-11-26
MY8400259A (en) 1984-12-31
IL60025A0 (en) 1980-07-31
JPH01199972A (ja) 1989-08-11
JPS55154973A (en) 1980-12-02
DE3070919D1 (en) 1985-09-05
HU184280B (en) 1984-07-30
GB2052480A (en) 1981-01-28
GB2052480B (en) 1983-03-16
SG29483G (en) 1985-01-11
CH654008A5 (fr) 1986-01-31
JPH0210835B2 (es) 1990-03-09
IL60025A (en) 1984-10-31
ES491683A0 (es) 1981-04-16

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970203