PH15971A - Hypoglycemic guanylamidines and their use as hypoglycemic agents - Google Patents
Hypoglycemic guanylamidines and their use as hypoglycemic agentsInfo
- Publication number
- PH15971A PH15971A PH25233A PH25233A PH15971A PH 15971 A PH15971 A PH 15971A PH 25233 A PH25233 A PH 25233A PH 25233 A PH25233 A PH 25233A PH 15971 A PH15971 A PH 15971A
- Authority
- PH
- Philippines
- Prior art keywords
- hypoglycemic
- guanylamidines
- agents
- hypoglycemic agents
- hypoglycemic guanylamidines
- Prior art date
Links
- 239000003472 antidiabetic agent Substances 0.000 title 1
- 229940126904 hypoglycaemic agent Drugs 0.000 title 1
- 230000002218 hypoglycaemic effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/53—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
- C07C279/22—Y being a hydrogen or a carbon atom, e.g. benzoylguanidines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/26—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
- C07D295/215—Radicals derived from nitrogen analogues of carbonic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Furan Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/122,155 US4269837A (en) | 1980-02-19 | 1980-02-19 | Hypoglycemic guanylamidines, compositions and use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PH15971A true PH15971A (en) | 1983-05-11 |
Family
ID=22401029
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PH25233A PH15971A (en) | 1980-02-19 | 1981-02-19 | Hypoglycemic guanylamidines and their use as hypoglycemic agents |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US4269837A (da) |
| EP (1) | EP0034495B1 (da) |
| JP (1) | JPS56147760A (da) |
| KR (1) | KR840000930B1 (da) |
| AR (1) | AR229350A1 (da) |
| AT (1) | ATE3425T1 (da) |
| AU (1) | AU517843B2 (da) |
| CA (1) | CA1145334A (da) |
| DE (1) | DE3160290D1 (da) |
| DK (1) | DK70881A (da) |
| ES (1) | ES499572A0 (da) |
| FI (1) | FI75343C (da) |
| GR (1) | GR78339B (da) |
| IE (1) | IE50924B1 (da) |
| IL (1) | IL62146A (da) |
| PH (1) | PH15971A (da) |
| PT (1) | PT72516B (da) |
| YU (1) | YU41968B (da) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4404219A (en) * | 1980-03-31 | 1983-09-13 | Pfizer Inc. | Phenylguanidine therapeutic agents |
| US5268373A (en) * | 1992-07-28 | 1993-12-07 | Mcneilab, Inc. | Guanidine derivatives, compositions and use |
| ES2164990T3 (es) * | 1996-04-30 | 2002-03-01 | Pfizer | Agonistas de receptores muscarinicos. |
| AR008290A1 (es) * | 1996-08-15 | 1999-12-29 | Smithkline Beecham Corp | Nuevos compuestos que contienen guanidina utiles como antagonistas de los receptores de il-8, composiciones farmaceuticas que los contienenprocedimiento para la preparacion de dichos compuestos y procedimiento para la preparacion de intermediarios. |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH478802A (de) | 1966-09-06 | 1969-09-30 | Sandoz Ag | Verfahren zur Herstellung von Pyrazolderivaten |
| CS225804B2 (cs) | 1976-03-19 | 1984-02-13 | Mcneilab Inc | Způsob výroby heterocyklických derivátů guanidinu |
-
1980
- 1980-02-19 US US06/122,155 patent/US4269837A/en not_active Expired - Lifetime
-
1981
- 1981-02-16 GR GR64154A patent/GR78339B/el unknown
- 1981-02-16 JP JP2133581A patent/JPS56147760A/ja active Granted
- 1981-02-16 AR AR284300A patent/AR229350A1/es active
- 1981-02-17 PT PT72516A patent/PT72516B/pt unknown
- 1981-02-17 AT AT81300634T patent/ATE3425T1/de not_active IP Right Cessation
- 1981-02-17 DE DE8181300634T patent/DE3160290D1/de not_active Expired
- 1981-02-17 CA CA000371114A patent/CA1145334A/en not_active Expired
- 1981-02-17 YU YU398/81A patent/YU41968B/xx unknown
- 1981-02-17 EP EP81300634A patent/EP0034495B1/en not_active Expired
- 1981-02-17 IL IL62146A patent/IL62146A/xx unknown
- 1981-02-17 IE IE311/81A patent/IE50924B1/en unknown
- 1981-02-18 KR KR1019810000507A patent/KR840000930B1/ko not_active Expired
- 1981-02-18 AU AU67408/81A patent/AU517843B2/en not_active Ceased
- 1981-02-18 DK DK70881A patent/DK70881A/da not_active Application Discontinuation
- 1981-02-18 ES ES499572A patent/ES499572A0/es active Granted
- 1981-02-18 FI FI810492A patent/FI75343C/fi not_active IP Right Cessation
- 1981-02-19 PH PH25233A patent/PH15971A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PT72516A (en) | 1981-03-01 |
| PT72516B (en) | 1982-10-21 |
| IL62146A (en) | 1984-09-30 |
| DE3160290D1 (en) | 1983-07-07 |
| CA1145334A (en) | 1983-04-26 |
| AR229350A1 (es) | 1983-07-29 |
| IL62146A0 (en) | 1981-03-31 |
| ES8201541A1 (es) | 1981-12-16 |
| YU39881A (en) | 1983-09-30 |
| FI75343C (fi) | 1988-06-09 |
| ES499572A0 (es) | 1981-12-16 |
| KR840000930B1 (ko) | 1984-06-29 |
| KR830005188A (ko) | 1983-08-03 |
| ATE3425T1 (de) | 1983-06-15 |
| IE810311L (en) | 1981-08-19 |
| YU41968B (en) | 1988-04-30 |
| EP0034495B1 (en) | 1983-05-18 |
| US4269837A (en) | 1981-05-26 |
| JPS6348265B2 (da) | 1988-09-28 |
| FI810492L (fi) | 1981-08-20 |
| DK70881A (da) | 1981-08-20 |
| JPS56147760A (en) | 1981-11-16 |
| IE50924B1 (en) | 1986-08-20 |
| AU517843B2 (en) | 1981-08-27 |
| FI75343B (fi) | 1988-02-29 |
| EP0034495A3 (en) | 1982-01-27 |
| EP0034495A2 (en) | 1981-08-26 |
| GR78339B (da) | 1984-09-26 |
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