FI810492L - Hypoglycemiska guanylamidiner - Google Patents

Hypoglycemiska guanylamidiner

Info

Publication number
FI810492L
FI810492L FI810492A FI810492A FI810492L FI 810492 L FI810492 L FI 810492L FI 810492 A FI810492 A FI 810492A FI 810492 A FI810492 A FI 810492A FI 810492 L FI810492 L FI 810492L
Authority
FI
Finland
Prior art keywords
hypoglycemisic
guanylamidiner
hypoglycemisic guanylamidiner
Prior art date
Application number
FI810492A
Other languages
English (en)
Other versions
FI75343B (fi
FI75343C (fi
Inventor
David Stewart Watt
Jeffrey Lee Ives
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of FI810492L publication Critical patent/FI810492L/fi
Publication of FI75343B publication Critical patent/FI75343B/fi
Application granted granted Critical
Publication of FI75343C publication Critical patent/FI75343C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/53Nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/20Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
    • C07C279/22Y being a hydrogen or a carbon atom, e.g. benzoylguanidines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/12Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/26Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/215Radicals derived from nitrogen analogues of carbonic acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/22Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
FI810492A 1980-02-19 1981-02-18 Foerfarande foer framstaellning av guanylamidiner, vilka aer anvaendbara som hypoglykemiska medel. FI75343C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/122,155 US4269837A (en) 1980-02-19 1980-02-19 Hypoglycemic guanylamidines, compositions and use
US12215580 1980-02-19

Publications (3)

Publication Number Publication Date
FI810492L true FI810492L (fi) 1981-08-20
FI75343B FI75343B (fi) 1988-02-29
FI75343C FI75343C (fi) 1988-06-09

Family

ID=22401029

Family Applications (1)

Application Number Title Priority Date Filing Date
FI810492A FI75343C (fi) 1980-02-19 1981-02-18 Foerfarande foer framstaellning av guanylamidiner, vilka aer anvaendbara som hypoglykemiska medel.

Country Status (18)

Country Link
US (1) US4269837A (fi)
EP (1) EP0034495B1 (fi)
JP (1) JPS56147760A (fi)
KR (1) KR840000930B1 (fi)
AR (1) AR229350A1 (fi)
AT (1) ATE3425T1 (fi)
AU (1) AU517843B2 (fi)
CA (1) CA1145334A (fi)
DE (1) DE3160290D1 (fi)
DK (1) DK70881A (fi)
ES (1) ES499572A0 (fi)
FI (1) FI75343C (fi)
GR (1) GR78339B (fi)
IE (1) IE50924B1 (fi)
IL (1) IL62146A (fi)
PH (1) PH15971A (fi)
PT (1) PT72516B (fi)
YU (1) YU41968B (fi)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4404219A (en) * 1980-03-31 1983-09-13 Pfizer Inc. Phenylguanidine therapeutic agents
US5268373A (en) * 1992-07-28 1993-12-07 Mcneilab, Inc. Guanidine derivatives, compositions and use
ATE208767T1 (de) * 1996-04-30 2001-11-15 Pfizer Muscarinische rezeptor-agonisten
AR008290A1 (es) * 1996-08-15 1999-12-29 Smithkline Beecham Corp Nuevos compuestos que contienen guanidina utiles como antagonistas de los receptores de il-8, composiciones farmaceuticas que los contienenprocedimiento para la preparacion de dichos compuestos y procedimiento para la preparacion de intermediarios.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH478802A (de) 1966-09-06 1969-09-30 Sandoz Ag Verfahren zur Herstellung von Pyrazolderivaten
CS225804B2 (cs) 1976-03-19 1984-02-13 Mcneilab Inc Způsob výroby heterocyklických derivátů guanidinu

Also Published As

Publication number Publication date
PT72516A (en) 1981-03-01
IE50924B1 (en) 1986-08-20
PH15971A (en) 1983-05-11
GR78339B (fi) 1984-09-26
KR840000930B1 (ko) 1984-06-29
FI75343B (fi) 1988-02-29
IL62146A0 (en) 1981-03-31
DE3160290D1 (en) 1983-07-07
AU517843B2 (en) 1981-08-27
YU41968B (en) 1988-04-30
ES8201541A1 (es) 1981-12-16
AR229350A1 (es) 1983-07-29
YU39881A (en) 1983-09-30
CA1145334A (en) 1983-04-26
ES499572A0 (es) 1981-12-16
FI75343C (fi) 1988-06-09
US4269837A (en) 1981-05-26
JPS56147760A (en) 1981-11-16
IL62146A (en) 1984-09-30
DK70881A (da) 1981-08-20
JPS6348265B2 (fi) 1988-09-28
IE810311L (en) 1981-08-19
EP0034495A3 (en) 1982-01-27
ATE3425T1 (de) 1983-06-15
PT72516B (en) 1982-10-21
EP0034495B1 (en) 1983-05-18
EP0034495A2 (en) 1981-08-26
KR830005188A (ko) 1983-08-03

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Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: PFIZER INC.