PH12013501255A1 - Anti-notch1 antibodies - Google Patents

Anti-notch1 antibodies

Info

Publication number
PH12013501255A1
PH12013501255A1 PH1/2013/501255A PH12013501255A PH12013501255A1 PH 12013501255 A1 PH12013501255 A1 PH 12013501255A1 PH 12013501255 A PH12013501255 A PH 12013501255A PH 12013501255 A1 PH12013501255 A1 PH 12013501255A1
Authority
PH
Philippines
Prior art keywords
antibodies
notch1 antibodies
notch1
pharmaceutical compositions
methods
Prior art date
Application number
PH1/2013/501255A
Other languages
English (en)
Inventor
Joel Bard
Yijie Gao
Kenneth G Geles
Lioudmila Gennadievna Tchistiakova
Bin-Bing Stephen Zhou
Original Assignee
Wyeth Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Llc filed Critical Wyeth Llc
Publication of PH12013501255A1 publication Critical patent/PH12013501255A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
PH1/2013/501255A 2010-12-15 2011-12-09 Anti-notch1 antibodies PH12013501255A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US42357810P 2010-12-15 2010-12-15
US201161552578P 2011-10-28 2011-10-28
PCT/IB2011/055595 WO2012080926A2 (en) 2010-12-15 2011-12-09 Anti-notch1 antibodies

Publications (1)

Publication Number Publication Date
PH12013501255A1 true PH12013501255A1 (en) 2013-08-05

Family

ID=45444674

Family Applications (2)

Application Number Title Priority Date Filing Date
PH1/2013/501255A PH12013501255A1 (en) 2010-12-15 2011-12-09 Anti-notch1 antibodies
PH12017500864A PH12017500864A1 (en) 2010-12-15 2017-05-10 Anti-notch1 antibodies

Family Applications After (1)

Application Number Title Priority Date Filing Date
PH12017500864A PH12017500864A1 (en) 2010-12-15 2017-05-10 Anti-notch1 antibodies

Country Status (19)

Country Link
US (2) US9127060B2 (cg-RX-API-DMAC7.html)
EP (1) EP2651977A2 (cg-RX-API-DMAC7.html)
JP (1) JP6016800B2 (cg-RX-API-DMAC7.html)
KR (2) KR20150088334A (cg-RX-API-DMAC7.html)
CN (2) CN103547594B (cg-RX-API-DMAC7.html)
AR (1) AR084315A1 (cg-RX-API-DMAC7.html)
AU (2) AU2011342799B2 (cg-RX-API-DMAC7.html)
BR (1) BR112013015122A2 (cg-RX-API-DMAC7.html)
CA (1) CA2821130C (cg-RX-API-DMAC7.html)
CO (1) CO6791565A2 (cg-RX-API-DMAC7.html)
MX (1) MX346995B (cg-RX-API-DMAC7.html)
NZ (1) NZ611785A (cg-RX-API-DMAC7.html)
PE (1) PE20141109A1 (cg-RX-API-DMAC7.html)
PH (2) PH12013501255A1 (cg-RX-API-DMAC7.html)
RU (1) RU2622083C2 (cg-RX-API-DMAC7.html)
SA (1) SA111330060B1 (cg-RX-API-DMAC7.html)
SG (1) SG191039A1 (cg-RX-API-DMAC7.html)
TW (1) TWI471333B (cg-RX-API-DMAC7.html)
WO (1) WO2012080926A2 (cg-RX-API-DMAC7.html)

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WO2008027986A2 (en) 2006-09-01 2008-03-06 Therapeutic Human Polyclonals, Inc. Enhanced expression of human or humanized immunoglobulin in non-human transgenic animals
JP5618544B2 (ja) 2007-01-24 2014-11-05 オンコメッドファーマシューティカルズ インコーポレイテッド 癌の診断および処置のための組成物および方法
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EP2443151A1 (en) 2009-06-18 2012-04-25 Pfizer Inc. Anti notch-1 antibodies
AU2011342799B2 (en) 2010-12-15 2016-06-09 Wyeth Llc Anti-Notch1 antibodies
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KR102499678B1 (ko) * 2020-02-27 2023-02-15 주식회사 베르티스 암의 진단용 조성물
KR20220029524A (ko) * 2020-08-31 2022-03-08 (주)메디톡스 항-ｖｅｇｆ 육량체 항체, 및 이를 포함하는 조성물
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Also Published As

Publication number Publication date
US9127060B2 (en) 2015-09-08
CA2821130C (en) 2017-11-07
NZ611785A (en) 2015-04-24
AR084315A1 (es) 2013-05-08
PE20141109A1 (es) 2014-09-24
AU2011342799A1 (en) 2013-07-04
CA2821130A1 (en) 2012-06-21
SA111330060B1 (ar) 2015-06-04
US20130266594A1 (en) 2013-10-10
KR20130108430A (ko) 2013-10-02
SG191039A1 (en) 2013-08-30
US20160002331A1 (en) 2016-01-07
JP2014503205A (ja) 2014-02-13
AU2016219704A1 (en) 2016-09-15
HK1194388A1 (zh) 2014-10-17
RU2622083C2 (ru) 2017-06-09
WO2012080926A2 (en) 2012-06-21
EP2651977A2 (en) 2013-10-23
TWI471333B (zh) 2015-02-01
KR20150088334A (ko) 2015-07-31
BR112013015122A2 (pt) 2017-05-30
CN103547594A (zh) 2014-01-29
MX2013006875A (es) 2013-07-05
JP6016800B2 (ja) 2016-10-26
CN103547594B (zh) 2016-05-11
KR101580726B1 (ko) 2015-12-29
PH12017500864A1 (en) 2017-12-11
MX346995B (es) 2017-04-06
TW201302787A (zh) 2013-01-16
RU2013126494A (ru) 2015-01-20
CO6791565A2 (es) 2013-11-14
WO2012080926A3 (en) 2012-10-04
AU2011342799B2 (en) 2016-06-09
CN105884896A (zh) 2016-08-24

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