PH12013500293A1 - Methods of treating alcohol intoxication, alcohol use disorders and alcohol abuse which comprise the administration of dihydromyricetin - Google Patents
Methods of treating alcohol intoxication, alcohol use disorders and alcohol abuse which comprise the administration of dihydromyricetinInfo
- Publication number
- PH12013500293A1 PH12013500293A1 PH1/2013/500293A PH12013500293A PH12013500293A1 PH 12013500293 A1 PH12013500293 A1 PH 12013500293A1 PH 12013500293 A PH12013500293 A PH 12013500293A PH 12013500293 A1 PH12013500293 A1 PH 12013500293A1
- Authority
- PH
- Philippines
- Prior art keywords
- alcohol
- dihydromyricetin
- administration
- methods
- treating
- Prior art date
Links
- KJXSIXMJHKAJOD-LSDHHAIUSA-N (+)-dihydromyricetin Chemical compound C1([C@@H]2[C@H](C(C3=C(O)C=C(O)C=C3O2)=O)O)=CC(O)=C(O)C(O)=C1 KJXSIXMJHKAJOD-LSDHHAIUSA-N 0.000 title abstract 6
- 208000007848 Alcoholism Diseases 0.000 title abstract 4
- KQILIWXGGKGKNX-UHFFFAOYSA-N dihydromyricetin Natural products OC1C(=C(Oc2cc(O)cc(O)c12)c3cc(O)c(O)c(O)c3)O KQILIWXGGKGKNX-UHFFFAOYSA-N 0.000 title abstract 3
- 206010001605 Alcohol poisoning Diseases 0.000 title abstract 2
- 206010001584 alcohol abuse Diseases 0.000 title abstract 2
- 208000025746 alcohol use disease Diseases 0.000 title abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 6
- 102000027484 GABAA receptors Human genes 0.000 abstract 4
- 108091008681 GABAA receptors Proteins 0.000 abstract 4
- SVUOLADPCWQTTE-UHFFFAOYSA-N 1h-1,2-benzodiazepine Chemical compound N1N=CC=CC2=CC=CC=C12 SVUOLADPCWQTTE-UHFFFAOYSA-N 0.000 abstract 1
- 229940049706 benzodiazepine Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Preparation or treatment thereof
- A23L2/52—Adding ingredients
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
- A23L29/03—Organic compounds
- A23L29/035—Organic compounds containing oxygen as heteroatom
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2200/00—Function of food ingredients
- A23V2200/30—Foods, ingredients or supplements having a functional effect on health
- A23V2200/334—Foods, ingredients or supplements having a functional effect on health treating the effects of consuming alcohol, narcotics or other addictive behavior, e.g. treating hangover or reducing blood alcohol levels
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Nutrition Science (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Hospice & Palliative Care (AREA)
- Toxicology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US37652810P | 2010-08-24 | 2010-08-24 | |
| PCT/US2011/048749 WO2012027326A2 (en) | 2010-08-24 | 2011-08-23 | Methods of treating alcohol intoxication, alcohol use disorders and alcohol abuse which comprise the administration of dihydromyricetin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PH12013500293A1 true PH12013500293A1 (en) | 2013-03-25 |
Family
ID=45724009
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PH1/2013/500293A PH12013500293A1 (en) | 2010-08-24 | 2011-08-23 | Methods of treating alcohol intoxication, alcohol use disorders and alcohol abuse which comprise the administration of dihydromyricetin |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20130053435A1 (enExample) |
| EP (1) | EP2608786A4 (enExample) |
| JP (1) | JP2013536238A (enExample) |
| KR (1) | KR20130098347A (enExample) |
| CN (1) | CN103269699A (enExample) |
| AU (1) | AU2011293556A1 (enExample) |
| BR (1) | BR112013003946A2 (enExample) |
| CA (1) | CA2808680A1 (enExample) |
| CL (1) | CL2013000518A1 (enExample) |
| EA (1) | EA201390217A1 (enExample) |
| MX (1) | MX2013002162A (enExample) |
| PH (1) | PH12013500293A1 (enExample) |
| SG (1) | SG187771A1 (enExample) |
| WO (1) | WO2012027326A2 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014007853A1 (en) * | 2012-07-03 | 2014-01-09 | The Regents Of The University Of California | Dihydromyricetin for the treatment of diseases and disorders of the glutamatergic system |
| CN103772338A (zh) * | 2014-01-10 | 2014-05-07 | 吉首大学 | 真空脉动式制备二氢杨梅素的方法 |
| EP3761979A4 (en) * | 2018-04-06 | 2021-06-30 | Ovid Therapeutics Inc. | USE OF GABOXADOL TO TREAT SUBSTANCE ABUSE |
| CN108567772A (zh) * | 2018-07-24 | 2018-09-25 | 广西师范大学 | 二氢杨梅素的新用途 |
| EP3876926A1 (de) * | 2018-11-05 | 2021-09-15 | Evanium Healthcare GmbH | Alkohol-antidot |
| US20200147032A1 (en) | 2018-11-14 | 2020-05-14 | Robert K. Prud'homme | Dihydromyricetin hot melt extrusion formulations and methods for forming them |
| TW202110437A (zh) * | 2019-05-23 | 2021-03-16 | 美商希諾瓦有限責任公司 | 用於酒精誘發之皮膚潮紅之治療及緩解的組成物及方法 |
| MX2021015457A (es) | 2019-06-14 | 2022-04-06 | Univ Princeton | Formulaciones de dihidromiricetina y un permeabilizante. |
| GR1010117B (el) | 2020-07-14 | 2021-11-08 | Uni Pharma Κλεων Τσετης Φαρμακευτικα Εργαστηρια Αβεε, | Διατροφικο συμπληρωμα για την απο του στοματος χορηγηση συνδυασμου διυδρομυρισετινης, χολινης και μιας ή περισσοτερων βιταμινων με αντιοξειδωτικη δραση, χρησιμων για τη φυσιολογικη λειτουργια του ηπατος |
| CN112546014B (zh) * | 2020-12-15 | 2023-01-31 | 铜仁职业技术学院 | 一种中药解酒护肝泡腾片及其制备方法 |
| CN118354770A (zh) * | 2021-10-07 | 2024-07-16 | 罗特格斯新泽西州立大学 | 具有gabaa受体活性的类黄酮衍生物及使用方法 |
| CN113842461B (zh) * | 2021-11-04 | 2023-08-11 | 杭州诺莘科技有限责任公司 | 用于缓解、治疗酒精中毒、酒后不适的gabaa受体结合物、组合物及其应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1293825C (zh) * | 2002-08-30 | 2007-01-10 | 广州拜迪生物医药有限公司 | 二氢杨梅树皮素在制备食品、化妆品或药品中的应用 |
| KR20040021927A (ko) * | 2002-09-06 | 2004-03-11 | 차재영 | 호깨나무와 홍삼 추출물을 이용한 건강 보조식품프로헤파-알지의 개발 |
| CN101336978B (zh) * | 2008-08-12 | 2013-01-30 | 西北农林科技大学 | 一种北枳椇总黄酮的提取方法 |
| CN101336987B (zh) * | 2008-08-12 | 2012-04-25 | 西北农林科技大学 | 一种枳椇总黄酮的制备方法 |
-
2011
- 2011-08-23 CA CA2808680A patent/CA2808680A1/en not_active Abandoned
- 2011-08-23 MX MX2013002162A patent/MX2013002162A/es not_active Application Discontinuation
- 2011-08-23 BR BR112013003946A patent/BR112013003946A2/pt not_active IP Right Cessation
- 2011-08-23 EP EP11820493.2A patent/EP2608786A4/en not_active Withdrawn
- 2011-08-23 JP JP2013526087A patent/JP2013536238A/ja active Pending
- 2011-08-23 SG SG2013009576A patent/SG187771A1/en unknown
- 2011-08-23 KR KR1020137007021A patent/KR20130098347A/ko not_active Withdrawn
- 2011-08-23 PH PH1/2013/500293A patent/PH12013500293A1/en unknown
- 2011-08-23 US US13/520,727 patent/US20130053435A1/en not_active Abandoned
- 2011-08-23 EA EA201390217A patent/EA201390217A1/ru unknown
- 2011-08-23 WO PCT/US2011/048749 patent/WO2012027326A2/en not_active Ceased
- 2011-08-23 CN CN201180048110XA patent/CN103269699A/zh active Pending
- 2011-08-23 AU AU2011293556A patent/AU2011293556A1/en not_active Abandoned
-
2013
- 2013-02-22 CL CL2013000518A patent/CL2013000518A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BR112013003946A2 (pt) | 2016-07-12 |
| MX2013002162A (es) | 2013-04-05 |
| CA2808680A1 (en) | 2012-03-01 |
| KR20130098347A (ko) | 2013-09-04 |
| WO2012027326A9 (en) | 2012-04-19 |
| EA201390217A1 (ru) | 2013-12-30 |
| US20130053435A1 (en) | 2013-02-28 |
| EP2608786A2 (en) | 2013-07-03 |
| AU2011293556A1 (en) | 2013-02-28 |
| SG187771A1 (en) | 2013-03-28 |
| CN103269699A (zh) | 2013-08-28 |
| JP2013536238A (ja) | 2013-09-19 |
| CL2013000518A1 (es) | 2013-08-02 |
| WO2012027326A2 (en) | 2012-03-01 |
| EP2608786A4 (en) | 2013-07-03 |
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