PE23396A1 - Benzotiofeno de glucopiranosido - Google Patents
Benzotiofeno de glucopiranosidoInfo
- Publication number
- PE23396A1 PE23396A1 PE1995268768A PE26876895A PE23396A1 PE 23396 A1 PE23396 A1 PE 23396A1 PE 1995268768 A PE1995268768 A PE 1995268768A PE 26876895 A PE26876895 A PE 26876895A PE 23396 A1 PE23396 A1 PE 23396A1
- Authority
- PE
- Peru
- Prior art keywords
- benzotiofen
- glucopyranoside
- chem
- solvate
- processes
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/10—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Steroid Compounds (AREA)
- Networks Using Active Elements (AREA)
- Photoreceptors In Electrophotography (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
SE REFIERE A UN COMPUESTO DE FORMULA (Ia) Y (Ib) O UNA DE SUS SALES O SOLVATOS FARMACEUTICAMENTE ACEPTABLES, DE PREFERENCIA CLORHIDRATO, QUE SE PUEDE HALLAR EN FORMA PURA O CON EXCIPIENTES PARA LA PREPARACION DE FORMAS FARMACEUTICAS Y A UN PROCEDIMIENTO PARA LA PREPARACION DE UN MATERIAL DE PARTIDA PARA LA SINTESIS DE DICHAS SALES DE APLICACION FARMACEUTICA, TODO EN MEDIO ANHIDRO. LAS SALES DE ADICION ACIDA SE FORMAN POR REACCION DEL COMPUESTO ANTES MENCIONADO CON UNA CANTIDAD EQUIMOLAR O EN EXCESO DE ACIDO, PROCESO QUE LLEVA A LA PRECIPITACION DE LA SAL EN UN LAPSO DE UNA HORA A 10 DIAS, AISLANDOSE POR FILTRACION, USANDOSE PARA LA FORMACION DE SALES, LAS BASES TALES COMO NH4OH, NAOH, CO3K2 ENTRE OTRAS. LAS SALES FARMACEUTICAMENTE ACEPTABLES TIENEN AUMENTADA LAS CARACTERISTICAS DE SOLUBILIDAD Y SUS FORMAS DE PRESENTACION SON LA ORAL, I.M., I.V. LOS COMPUESTOS OBTENIDOS SON UTILES PARA LA DISMINUCION DE LOS NIVELES DE COLESTEROL EN SUERO Y LA INHIBICION DE LA RESORCION OSEA
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24665594A | 1994-05-20 | 1994-05-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE23396A1 true PE23396A1 (es) | 1996-06-15 |
Family
ID=22931623
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE1995268768A PE23396A1 (es) | 1994-05-20 | 1995-05-16 | Benzotiofeno de glucopiranosido |
Country Status (27)
| Country | Link |
|---|---|
| US (2) | US5567820A (es) |
| EP (1) | EP0683170B1 (es) |
| JP (1) | JPH07316180A (es) |
| KR (1) | KR950032183A (es) |
| CN (1) | CN1039013C (es) |
| AT (1) | ATE184880T1 (es) |
| AU (1) | AU683734B2 (es) |
| BR (1) | BR9502079A (es) |
| CA (1) | CA2149501A1 (es) |
| CO (1) | CO4650137A1 (es) |
| CZ (1) | CZ126295A3 (es) |
| DE (1) | DE69512310T2 (es) |
| DK (1) | DK0683170T3 (es) |
| ES (1) | ES2136799T3 (es) |
| FI (1) | FI952420A (es) |
| GR (1) | GR3032142T3 (es) |
| HU (1) | HU219335B (es) |
| IL (1) | IL113780A (es) |
| NO (1) | NO304694B1 (es) |
| NZ (1) | NZ272131A (es) |
| PE (1) | PE23396A1 (es) |
| PL (1) | PL308635A1 (es) |
| RU (1) | RU95107655A (es) |
| SI (1) | SI0683170T1 (es) |
| TW (1) | TW323285B (es) |
| YU (1) | YU31995A (es) |
| ZA (1) | ZA953975B (es) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0724879A2 (en) * | 1995-02-06 | 1996-08-07 | Eli Lilly And Company | 2-Phenyl-3-azoylbenzothiopenes for inhibiting effects of IL-6 |
| US20040167080A1 (en) * | 1995-03-15 | 2004-08-26 | Dodge Jeffrey A. | Glucopyranoside benzothiophenes |
| ES2341399T3 (es) | 1996-03-26 | 2010-06-18 | Eli Lilly And Company | Benziotofenos, formulaciones que contienen los mismos y procedimientos. |
| US6458811B1 (en) | 1996-03-26 | 2002-10-01 | Eli Lilly And Company | Benzothiophenes formulations containing same and methods |
| ES2246234T3 (es) | 1999-05-04 | 2006-02-16 | Strakan International Limited | Glicosidos de androgenos y actividad androgenica de los mismos. |
| JP2003509435A (ja) * | 1999-09-13 | 2003-03-11 | ワイス | ２−（４−ヒドロキシフェニル）−１−［４−（２−アミン−１−イルエトキシ）ベンジル］−１ｈ−インドール−５−オールのグルコピラノシド複合体 |
| US6380166B1 (en) | 1999-09-13 | 2002-04-30 | American Home Products Corporation | Glucopyranosides conjugates of 2-(4-hydroxy-phenyl)-3-methyl-1-[4-(2-amin-1-yl-ethoxy)-benzyl]-1H-indol-5-ols |
| WO2001027129A1 (en) * | 1999-10-08 | 2001-04-19 | Strakan Limited | Glycosides and orthoester glycosides of raloxifene and analogues and the use thereof |
| AU7674000A (en) * | 1999-10-08 | 2001-04-23 | Strakan Group Plc | Tamoxifen and tamoxifen analogue glycosides and uses thereof |
| WO2011029088A2 (en) * | 2009-09-07 | 2011-03-10 | Dr. Reddy's Laboratories Ltd. | Preparation of raloxifene and its salts |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4133814A (en) | 1975-10-28 | 1979-01-09 | Eli Lilly And Company | 2-Phenyl-3-aroylbenzothiophenes useful as antifertility agents |
| US4418068A (en) | 1981-04-03 | 1983-11-29 | Eli Lilly And Company | Antiestrogenic and antiandrugenic benzothiophenes |
| TW366342B (en) * | 1992-07-28 | 1999-08-11 | Lilly Co Eli | The use of 2-phenyl-3-aroylbenzothiophenes in inhibiting bone loss |
-
1995
- 1995-03-15 US US08/404,701 patent/US5567820A/en not_active Expired - Fee Related
- 1995-03-15 US US08/405,555 patent/US6723739B1/en not_active Expired - Fee Related
- 1995-05-16 DK DK95303265T patent/DK0683170T3/da active
- 1995-05-16 DE DE69512310T patent/DE69512310T2/de not_active Expired - Fee Related
- 1995-05-16 RU RU95107655/04A patent/RU95107655A/ru unknown
- 1995-05-16 CZ CZ951262A patent/CZ126295A3/cs unknown
- 1995-05-16 ES ES95303265T patent/ES2136799T3/es not_active Expired - Lifetime
- 1995-05-16 CA CA002149501A patent/CA2149501A1/en not_active Abandoned
- 1995-05-16 TW TW084104846A patent/TW323285B/zh active
- 1995-05-16 PE PE1995268768A patent/PE23396A1/es not_active Application Discontinuation
- 1995-05-16 SI SI9530336T patent/SI0683170T1/xx unknown
- 1995-05-16 ZA ZA953975A patent/ZA953975B/xx unknown
- 1995-05-16 AT AT95303265T patent/ATE184880T1/de not_active IP Right Cessation
- 1995-05-16 NZ NZ272131A patent/NZ272131A/en unknown
- 1995-05-16 EP EP95303265A patent/EP0683170B1/en not_active Expired - Lifetime
- 1995-05-17 JP JP7118338A patent/JPH07316180A/ja not_active Withdrawn
- 1995-05-17 AU AU20121/95A patent/AU683734B2/en not_active Ceased
- 1995-05-17 PL PL95308635A patent/PL308635A1/xx unknown
- 1995-05-17 KR KR1019950012173A patent/KR950032183A/ko not_active Application Discontinuation
- 1995-05-18 HU HU9501466A patent/HU219335B/hu not_active IP Right Cessation
- 1995-05-18 BR BR9502079A patent/BR9502079A/pt not_active Application Discontinuation
- 1995-05-18 CN CN95106322A patent/CN1039013C/zh not_active Expired - Fee Related
- 1995-05-18 FI FI952420A patent/FI952420A/fi unknown
- 1995-05-18 IL IL11378095A patent/IL113780A/xx active IP Right Grant
- 1995-05-18 CO CO95021224A patent/CO4650137A1/es unknown
- 1995-05-18 NO NO951322A patent/NO304694B1/no not_active IP Right Cessation
- 1995-05-18 YU YU31995A patent/YU31995A/sh unknown
-
1999
- 1999-12-15 GR GR990403228T patent/GR3032142T3/el unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK0582788T3 (da) | 7-(Substituerede)-9-[(substitueret glycyl)-amido]-demethyl-6-deoxytetracycliner | |
| SG77195A1 (en) | Fungicidal 2-methoxybenzophenones | |
| PT705833E (pt) | Derivado de dc-89 | |
| ES2088537T3 (es) | Derivados de piranil cianoguanidina. | |
| NO20014925D0 (no) | Farmasöytiske forbindelser | |
| ES2136887T3 (es) | Derivados antifungicos de sordaridina. | |
| PL326024A1 (en) | Novel derivatives of cyclodepsipeptidic substance pf1022 | |
| ES2136799T3 (es) | Benzotiofenos de glucopiranosido. | |
| ES2196174T3 (es) | `derivados de sesquiterpeno de actividad antiviral. | |
| RU93051079A (ru) | Фармацевтические соединения, способ получения, фармацевтическая композиция | |
| ATE197953T1 (de) | Pyrrolo(4,3,2-de)chinolin-derivat | |
| ATE187331T1 (de) | Benzopyranderivate | |
| SE9602418D0 (sv) | Process for the preparation of organic salts of N'N-diacetylcystine | |
| SE9602476D0 (sv) | Process for the preparation of organic salts of N'N -diacetylcystine |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FX | Voluntary withdrawal |