IL113780A - Glucopyranoside benzothiophenes process for their preparation and pharmaceutical compositions containing them - Google Patents

Glucopyranoside benzothiophenes process for their preparation and pharmaceutical compositions containing them

Info

Publication number
IL113780A
IL113780A IL11378095A IL11378095A IL113780A IL 113780 A IL113780 A IL 113780A IL 11378095 A IL11378095 A IL 11378095A IL 11378095 A IL11378095 A IL 11378095A IL 113780 A IL113780 A IL 113780A
Authority
IL
Israel
Prior art keywords
preparation
benzothiophenes
glucopyranoside
pharmaceutical compositions
compositions containing
Prior art date
Application number
IL11378095A
Other languages
English (en)
Other versions
IL113780A0 (en
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of IL113780A0 publication Critical patent/IL113780A0/xx
Publication of IL113780A publication Critical patent/IL113780A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/10—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Steroid Compounds (AREA)
  • Networks Using Active Elements (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
IL11378095A 1994-05-20 1995-05-18 Glucopyranoside benzothiophenes process for their preparation and pharmaceutical compositions containing them IL113780A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US24665594A 1994-05-20 1994-05-20

Publications (2)

Publication Number Publication Date
IL113780A0 IL113780A0 (en) 1995-08-31
IL113780A true IL113780A (en) 1999-06-20

Family

ID=22931623

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11378095A IL113780A (en) 1994-05-20 1995-05-18 Glucopyranoside benzothiophenes process for their preparation and pharmaceutical compositions containing them

Country Status (27)

Country Link
US (2) US5567820A (xx)
EP (1) EP0683170B1 (xx)
JP (1) JPH07316180A (xx)
KR (1) KR950032183A (xx)
CN (1) CN1039013C (xx)
AT (1) ATE184880T1 (xx)
AU (1) AU683734B2 (xx)
BR (1) BR9502079A (xx)
CA (1) CA2149501A1 (xx)
CO (1) CO4650137A1 (xx)
CZ (1) CZ126295A3 (xx)
DE (1) DE69512310T2 (xx)
DK (1) DK0683170T3 (xx)
ES (1) ES2136799T3 (xx)
FI (1) FI952420A (xx)
GR (1) GR3032142T3 (xx)
HU (1) HU219335B (xx)
IL (1) IL113780A (xx)
NO (1) NO304694B1 (xx)
NZ (1) NZ272131A (xx)
PE (1) PE23396A1 (xx)
PL (1) PL308635A1 (xx)
RU (1) RU95107655A (xx)
SI (1) SI0683170T1 (xx)
TW (1) TW323285B (xx)
YU (1) YU31995A (xx)
ZA (1) ZA953975B (xx)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0724879A2 (en) * 1995-02-06 1996-08-07 Eli Lilly And Company 2-Phenyl-3-azoylbenzothiopenes for inhibiting effects of IL-6
US20040167080A1 (en) * 1995-03-15 2004-08-26 Dodge Jeffrey A. Glucopyranoside benzothiophenes
ES2341399T3 (es) 1996-03-26 2010-06-18 Eli Lilly And Company Benziotofenos, formulaciones que contienen los mismos y procedimientos.
US6458811B1 (en) 1996-03-26 2002-10-01 Eli Lilly And Company Benzothiophenes formulations containing same and methods
ES2246234T3 (es) 1999-05-04 2006-02-16 Strakan International Limited Glicosidos de androgenos y actividad androgenica de los mismos.
JP2003509435A (ja) * 1999-09-13 2003-03-11 ワイス ２−（４−ヒドロキシフェニル）−１−［４−（２−アミン−１−イルエトキシ）ベンジル］−１ｈ−インドール−５−オールのグルコピラノシド複合体
US6380166B1 (en) 1999-09-13 2002-04-30 American Home Products Corporation Glucopyranosides conjugates of 2-(4-hydroxy-phenyl)-3-methyl-1-[4-(2-amin-1-yl-ethoxy)-benzyl]-1H-indol-5-ols
WO2001027129A1 (en) * 1999-10-08 2001-04-19 Strakan Limited Glycosides and orthoester glycosides of raloxifene and analogues and the use thereof
AU7674000A (en) * 1999-10-08 2001-04-23 Strakan Group Plc Tamoxifen and tamoxifen analogue glycosides and uses thereof
WO2011029088A2 (en) * 2009-09-07 2011-03-10 Dr. Reddy's Laboratories Ltd. Preparation of raloxifene and its salts

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4133814A (en) 1975-10-28 1979-01-09 Eli Lilly And Company 2-Phenyl-3-aroylbenzothiophenes useful as antifertility agents
US4418068A (en) 1981-04-03 1983-11-29 Eli Lilly And Company Antiestrogenic and antiandrugenic benzothiophenes
TW366342B (en) * 1992-07-28 1999-08-11 Lilly Co Eli The use of 2-phenyl-3-aroylbenzothiophenes in inhibiting bone loss

Also Published As

Publication number Publication date
KR950032183A (ko) 1995-12-20
ES2136799T3 (es) 1999-12-01
EP0683170A1 (en) 1995-11-22
CZ126295A3 (en) 1995-12-13
RU95107655A (ru) 1997-02-10
DE69512310D1 (de) 1999-10-28
CN1116626A (zh) 1996-02-14
NZ272131A (en) 1996-11-26
CO4650137A1 (es) 1998-09-03
JPH07316180A (ja) 1995-12-05
HU9501466D0 (en) 1995-06-28
FI952420A (fi) 1995-11-21
SI0683170T1 (en) 2000-02-29
PL308635A1 (en) 1995-11-27
CN1039013C (zh) 1998-07-08
HUT73788A (en) 1996-09-30
PE23396A1 (es) 1996-06-15
ZA953975B (en) 1996-11-18
US6723739B1 (en) 2004-04-20
DE69512310T2 (de) 2000-02-03
CA2149501A1 (en) 1995-11-21
AU683734B2 (en) 1997-11-20
HU219335B (en) 2001-03-28
NO951954D0 (no) 1995-05-18
BR9502079A (pt) 1996-03-05
ATE184880T1 (de) 1999-10-15
YU31995A (sh) 1998-12-23
GR3032142T3 (en) 2000-04-27
AU2012195A (en) 1995-11-30
IL113780A0 (en) 1995-08-31
DK0683170T3 (da) 1999-12-20
US5567820A (en) 1996-10-22
FI952420A0 (fi) 1995-05-18
NO951954L (no) 1995-11-21
TW323285B (xx) 1997-12-21
NO304694B1 (no) 1999-02-01
EP0683170B1 (en) 1999-09-22

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed