PE20221833A1 - Composiciones topicas disenadas para mantener y/o restaurar la integridad de la mucosa y epidermis danada - Google Patents

Composiciones topicas disenadas para mantener y/o restaurar la integridad de la mucosa y epidermis danada

Info

Publication number
PE20221833A1
PE20221833A1 PE2022001497A PE2022001497A PE20221833A1 PE 20221833 A1 PE20221833 A1 PE 20221833A1 PE 2022001497 A PE2022001497 A PE 2022001497A PE 2022001497 A PE2022001497 A PE 2022001497A PE 20221833 A1 PE20221833 A1 PE 20221833A1
Authority
PE
Peru
Prior art keywords
epidermis
weight
integrity
damaged
topical compositions
Prior art date
Application number
PE2022001497A
Other languages
English (en)
Inventor
Roberto Cerini
Original Assignee
Ricerfarma Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ricerfarma Srl filed Critical Ricerfarma Srl
Publication of PE20221833A1 publication Critical patent/PE20221833A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728—Hyaluronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0208—Tissues; Wipes; Patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/41—Amines
    • A61K8/416—Quaternary ammonium compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/676—Ascorbic acid, i.e. vitamin C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0031—Rectum, anus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0046—Ear
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Gynecology & Obstetrics (AREA)
  • Nutrition Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Otolaryngology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Physiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

La presente invencion se refiere a composiciones topicas para el mantenimiento y/o restauracion de la integridad de las membranas mucosas y epidermis danadas. Se refiere a una combinacion de acido hialuronico de alto peso molecular, un ester de acido ascorbico, preferentemente palmitato de ascorbilo, en concentraciones menores o iguales al 0.05% en peso, y alfoscerato de colina en una matriz bio/mucoadhesiva. Esta combinacion es util para el tratamiento de afecciones irritativas/inflamatorias de las membranas mucosas y epidermis danadas (quemaduras, llagas, irritacion por calor, dermatitis y similares). Tambien se refiere a composiciones mucoadhesivas topicas caracterizadas porque comprenden acido hialuronico o una sal del mismo, alfoscerato de colina, palmitato de ascorbilo en una concentracion que oscila entre el 0.050% en peso y el 0.0004% en peso, y al menos un excipiente o portador farmaceuticamente aceptable.
PE2022001497A 2020-02-27 2021-02-25 Composiciones topicas disenadas para mantener y/o restaurar la integridad de la mucosa y epidermis danada PE20221833A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT102020000004069A IT202000004069A1 (it) 2020-02-27 2020-02-27 Composizioni topiche per il mantenimento e/o ripristino dell’integrità delle mucose e dell’epidermide lesa
PCT/IB2021/051573 WO2021171215A1 (en) 2020-02-27 2021-02-25 Topical compositions designed to maintain and/or restore the integrity of the mucosa and damaged epidermis

Publications (1)

Publication Number Publication Date
PE20221833A1 true PE20221833A1 (es) 2022-11-29

Family

ID=70738958

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2022001497A PE20221833A1 (es) 2020-02-27 2021-02-25 Composiciones topicas disenadas para mantener y/o restaurar la integridad de la mucosa y epidermis danada

Country Status (22)

Country Link
US (2) US20230114487A1 (es)
EP (1) EP4110288B1 (es)
JP (1) JP2023522295A (es)
KR (1) KR20220146582A (es)
CN (1) CN115209873A (es)
AU (1) AU2021225476A1 (es)
BR (1) BR112022016597A2 (es)
CA (1) CA3169514A1 (es)
CL (1) CL2022002324A1 (es)
CO (1) CO2022010763A2 (es)
DK (1) DK4110288T3 (es)
IL (1) IL295822A (es)
IT (1) IT202000004069A1 (es)
LT (1) LT4110288T (es)
MA (1) MA58793B1 (es)
MX (1) MX2022010645A (es)
PE (1) PE20221833A1 (es)
PT (1) PT4110288T (es)
RS (1) RS65451B1 (es)
SI (1) SI4110288T1 (es)
WO (1) WO2021171215A1 (es)
ZA (1) ZA202210572B (es)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH683671A5 (it) 1992-03-30 1994-04-29 Golgi Sa Uso topico di glicerofosfolipidi deacilati.
ITMI20020756A1 (it) * 2002-04-09 2003-10-09 Sinclair Pharma S R L Composizioni farmaceutiche topiche per il trattamento delle dermatiti
DE102004002001A1 (de) * 2004-01-14 2005-08-11 Reinmüller, Johannes, Dr.med. Mittel zur Behandlung von entzündlichen Erkrankungen
US20070196311A1 (en) * 2006-02-21 2007-08-23 Gross Dennis F Methods and kits for topical administration of hyaluronic acid
FR2946252B1 (fr) * 2009-06-08 2011-07-29 Fabre Pierre Dermo Cosmetique Bis esters d'acide gras insature sur l'acide ascorbique et leurs utilisations cosmetiques
IT1402907B1 (it) * 2010-11-30 2013-09-27 Ricerfarma Srl Composizioni topiche per mantenere o ripristinare l'integrita' delle mucose.

Also Published As

Publication number Publication date
MX2022010645A (es) 2022-09-23
LT4110288T (lt) 2024-04-25
IL295822A (en) 2022-10-01
JP2023522295A (ja) 2023-05-30
EP4110288A1 (en) 2023-01-04
SI4110288T1 (sl) 2024-05-31
US20240024352A1 (en) 2024-01-25
CA3169514A1 (en) 2021-09-02
CO2022010763A2 (es) 2022-08-19
WO2021171215A1 (en) 2021-09-02
KR20220146582A (ko) 2022-11-01
ZA202210572B (en) 2024-01-31
CN115209873A (zh) 2022-10-18
BR112022016597A2 (pt) 2023-04-04
US20230114487A1 (en) 2023-04-13
MA58793B1 (fr) 2024-04-30
RS65451B1 (sr) 2024-05-31
EP4110288B1 (en) 2024-03-27
DK4110288T3 (da) 2024-04-22
IT202000004069A1 (it) 2021-08-27
PT4110288T (pt) 2024-05-02
CL2022002324A1 (es) 2023-03-31
AU2021225476A1 (en) 2022-10-13

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