PE20221340A1 - Compuestos heterociclicos - Google Patents
Compuestos heterociclicosInfo
- Publication number
- PE20221340A1 PE20221340A1 PE2022000360A PE2022000360A PE20221340A1 PE 20221340 A1 PE20221340 A1 PE 20221340A1 PE 2022000360 A PE2022000360 A PE 2022000360A PE 2022000360 A PE2022000360 A PE 2022000360A PE 20221340 A1 PE20221340 A1 PE 20221340A1
- Authority
- PE
- Peru
- Prior art keywords
- heterocyclic compounds
- compounds
- pirido
- oxazin
- hexahydro
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5383—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/485—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Psychiatry (AREA)
- Inorganic Chemistry (AREA)
- Rheumatology (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Immunology (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
SE REFIERE A COMPUESTOS HETEROCICLICOS DERIVADOS DE (-) O (+)-TRANS-HEXAHIDRO-2H-PIRIDO[4,3-B][1,4]OXAZIN-3(4H)-ONA DE ACUERDO CON LAS FORMULAS (Ia) y (Ib), EN DONDE A, B Y L SON COMO SE DESCRIBEN EN LA PRESENTE, PROCESO DE FABRICACION DE LOS COMPUESTOS Y COMPOSICIONES QUE INCLUYEN LOS COMPUESTOS.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP19199122 | 2019-09-24 | ||
PCT/EP2020/076346 WO2021058444A1 (en) | 2019-09-24 | 2020-09-22 | Heterocyclic compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
PE20221340A1 true PE20221340A1 (es) | 2022-09-13 |
Family
ID=68066579
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE2022000360A PE20221340A1 (es) | 2019-09-24 | 2020-09-22 | Compuestos heterociclicos |
Country Status (16)
Country | Link |
---|---|
US (2) | US20210094972A1 (es) |
EP (1) | EP4034541A1 (es) |
JP (1) | JP2022549304A (es) |
KR (1) | KR20220066893A (es) |
CN (1) | CN114364684A (es) |
AR (1) | AR120029A1 (es) |
AU (1) | AU2020356241A1 (es) |
BR (1) | BR112022003357A2 (es) |
CA (1) | CA3155724A1 (es) |
CO (1) | CO2022002336A2 (es) |
CR (1) | CR20220117A (es) |
IL (1) | IL289595A (es) |
MX (1) | MX2022002831A (es) |
PE (1) | PE20221340A1 (es) |
TW (1) | TW202126662A (es) |
WO (1) | WO2021058444A1 (es) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AR114136A1 (es) | 2017-10-10 | 2020-07-29 | Hoffmann La Roche | Compuestos heterocíclicos |
JP7269948B2 (ja) | 2017-11-28 | 2023-05-09 | エフ. ホフマン-ラ ロシュ アーゲー | 新規複素環式化合物 |
JP7269943B2 (ja) | 2018-01-08 | 2023-05-09 | エフ. ホフマン-ラ ロシュ アーゲー | Magl阻害剤としてのオクタヒドロピリド[1,2-アルファ]ピラジン |
MX2021001433A (es) | 2018-08-13 | 2021-04-12 | Hoffmann La Roche | Nuevos compuestos heterociclicos como inhibidores de la monoacilglicerol lipasa. |
CN114269755A (zh) | 2019-09-12 | 2022-04-01 | 豪夫迈·罗氏有限公司 | 作为magl抑制剂的4,4a,5,7,8,8a-六吡啶并[4,3-b][1,4]噁嗪-3-酮化合物 |
CR20230115A (es) | 2020-09-03 | 2023-04-11 | Hoffmann La Roche | Compuestos heterocíclicos |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7579495B2 (en) | 2003-12-19 | 2009-08-25 | Momentive Performance Materials Inc. | Active-releasing cyclic siloxanes |
WO2011059118A1 (ko) | 2009-11-10 | 2011-05-19 | Kim Hyun Jeen | 후각인지능력 검사 시스템 |
WO2016158956A1 (ja) * | 2015-03-30 | 2016-10-06 | 武田薬品工業株式会社 | 複素環化合物 |
US10407407B2 (en) | 2015-05-21 | 2019-09-10 | Glaxosmithkline Intellectual Property Development Limited | Benzoimidazole derivatives as PAD4 inhibitors |
JP7269948B2 (ja) * | 2017-11-28 | 2023-05-09 | エフ. ホフマン-ラ ロシュ アーゲー | 新規複素環式化合物 |
TW201930300A (zh) * | 2017-12-15 | 2019-08-01 | 瑞士商赫孚孟拉羅股份公司 | 新雜環化合物 |
SG11202007608UA (en) * | 2018-03-22 | 2020-09-29 | Hoffmann La Roche | Oxazine monoacylglycerol lipase (magl) inhibitors |
MX2021001433A (es) * | 2018-08-13 | 2021-04-12 | Hoffmann La Roche | Nuevos compuestos heterociclicos como inhibidores de la monoacilglicerol lipasa. |
CR20210056A (es) * | 2018-08-13 | 2021-03-02 | Hoffmann La Roche | Nuevos compuestos heterocíclicos como inhibidores de monoacilglicerol lipasa |
-
2020
- 2020-09-22 US US17/027,952 patent/US20210094972A1/en not_active Abandoned
- 2020-09-22 MX MX2022002831A patent/MX2022002831A/es unknown
- 2020-09-22 EP EP20780980.7A patent/EP4034541A1/en active Pending
- 2020-09-22 JP JP2022518712A patent/JP2022549304A/ja active Pending
- 2020-09-22 AR ARP200102632A patent/AR120029A1/es unknown
- 2020-09-22 BR BR112022003357A patent/BR112022003357A2/pt not_active Application Discontinuation
- 2020-09-22 WO PCT/EP2020/076346 patent/WO2021058444A1/en unknown
- 2020-09-22 CA CA3155724A patent/CA3155724A1/en active Pending
- 2020-09-22 PE PE2022000360A patent/PE20221340A1/es unknown
- 2020-09-22 AU AU2020356241A patent/AU2020356241A1/en active Pending
- 2020-09-22 CN CN202080063290.8A patent/CN114364684A/zh active Pending
- 2020-09-22 KR KR1020227009404A patent/KR20220066893A/ko unknown
- 2020-09-22 CR CR20220117A patent/CR20220117A/es unknown
- 2020-09-23 TW TW109132829A patent/TW202126662A/zh unknown
-
2021
- 2021-12-16 US US17/552,816 patent/US20220106328A1/en not_active Abandoned
-
2022
- 2022-01-03 IL IL289595A patent/IL289595A/en unknown
- 2022-02-28 CO CONC2022/0002336A patent/CO2022002336A2/es unknown
Also Published As
Publication number | Publication date |
---|---|
KR20220066893A (ko) | 2022-05-24 |
AU2020356241A1 (en) | 2022-02-17 |
CN114364684A (zh) | 2022-04-15 |
CA3155724A1 (en) | 2021-04-01 |
CO2022002336A2 (es) | 2022-04-08 |
CR20220117A (es) | 2022-04-20 |
US20220106328A1 (en) | 2022-04-07 |
IL289595A (en) | 2022-03-01 |
JP2022549304A (ja) | 2022-11-24 |
MX2022002831A (es) | 2022-04-06 |
US20210094972A1 (en) | 2021-04-01 |
BR112022003357A2 (pt) | 2022-05-17 |
TW202126662A (zh) | 2021-07-16 |
WO2021058444A1 (en) | 2021-04-01 |
EP4034541A1 (en) | 2022-08-03 |
AR120029A1 (es) | 2022-01-26 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
PE20221340A1 (es) | Compuestos heterociclicos | |
CL2022000556A1 (es) | Compuestos de 4,4a,5,7,8,8a-hexapirido[4,3-b][1,4]oxazin-3-ona como inhibidores de magl | |
CO2021002382A2 (es) | Nuevos compuestos heterocíclicos como inhibidores de la monoacilglicerol lipasa | |
CR20170573A (es) | Lactamas bicíclicas y métodos de uso de las mismas | |
CO2020009567A2 (es) | Inhibidores de monoacilglicerol lipasa (magl) de oxazina | |
CO2022003062A2 (es) | Compuestos heterocíclicos | |
CO2022002339A2 (es) | Compuestos de 4,4a,5,7,8,8a-hexapirido[4,3-b][1,4]oxazin-3-ona como inhibidores de magl | |
CL2021000361A1 (es) | Nuevos compuestos heterocíclicos como inhibidores de monoacilglicerol lipasa | |
CR20170316A (es) | Compuestos de pirazina para el tratamiento de enfermedades infecciosas | |
CR20190087A (es) | Nuevos compuestos sulfonimidoilpurinova 7-sustituídos y derivados para el tratamiento y la profilaxis de la infección vírica | |
CO2022002000A2 (es) | Nuevos inhibidores heterocíclicos de monoacilglicerol lipasa (magl) | |
UY32553A (es) | Nuevos derivados de la pirrolidinadiona espiroheterocíclicos 3-sustituidos | |
CO2020000134A2 (es) | Compuestos cetónicos bicíclicos y métodos de uso de los mismos | |
UY31367A1 (es) | Derivados de nicotinamida, su preparacion y su aplicacion en terapeutica | |
CR20140336A (es) | Nuevos derivados de fosfatos, su procedimiento de preparación y las composiciones farmacéuticas que los contienen | |
DOP2006000017A (es) | Pirazolopiridinas y sales de las mismas, una composición farmaceútica que comprende dichos compuestos, un método para prepararlos y su uso | |
CL2021002770A1 (es) | Compuestos de 4h-pirrolo[3,2-c]piridin-4-ona | |
CO2018007278A2 (es) | Derivados de ácido aminobenzoico metaazacíclico como antagonistas de la integrina pan | |
CR20160064A (es) | Compuestos de benzoxaborol tricíclicos y usos de los mismos | |
CO2017003004A2 (es) | Nuevas triazolo[4,5-d]pirimidinas | |
CO2017008809A2 (es) | Compuestos de benzoxaborol y uso de los mismos | |
CO2018011231A2 (es) | Derivados de [1,2,3]triazolo[4,5-d]pirimidina con afinidad por los receptores canabinoides tipo-2 | |
CR20230115A (es) | Compuestos heterocíclicos | |
CO2021013166A2 (es) | Compuestos de hexahidro-1h-pirazino[1,2-a]pirazina para el tratamiento de una enfermedad autoinmunitaria | |
UY29879A1 (es) | Derivados de 6-heteroarilpiridoindolona, su preparación y su aplicación en terapéutica |