PE20212105A1 - Metodos para purificar un extracto de alergeno - Google Patents

Metodos para purificar un extracto de alergeno

Info

Publication number
PE20212105A1
PE20212105A1 PE2021001195A PE2021001195A PE20212105A1 PE 20212105 A1 PE20212105 A1 PE 20212105A1 PE 2021001195 A PE2021001195 A PE 2021001195A PE 2021001195 A PE2021001195 A PE 2021001195A PE 20212105 A1 PE20212105 A1 PE 20212105A1
Authority
PE
Peru
Prior art keywords
allergen extract
purify
methods
allergen
purified
Prior art date
Application number
PE2021001195A
Other languages
English (en)
Inventor
Marta Roman-Escutia
Maria Morales
Maria Teresa Gallego
Sanchez Jeronimo Carnes
Original Assignee
Leti Pharma S L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leti Pharma S L filed Critical Leti Pharma S L
Publication of PE20212105A1 publication Critical patent/PE20212105A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/68—Protozoa, e.g. flagella, amoebas, sporozoans, plasmodium or toxoplasma
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/63—Arthropods
    • A61K35/646—Arachnids, e.g. spiders, scorpions, ticks or mites
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/35—Fat tissue; Adipocytes; Stromal cells; Connective tissues
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Insects & Arthropods (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Dermatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La invencion se refiere a procesos para producir extractos de alergenos semipurificados y purificados, composiciones farmaceuticas y vacunas para uso en el diagnostico y tratamiento de alergia. En un aspecto de la invencion, se proporciona un proceso para producir un extracto de alergeno despigmentado, el proceso que comprende: a) basificar un extracto de alergeno nativo; y b) remover moleculas que tienen un tamano molecular de menos de 3.5 kDa; y c) ajustar el pH a neutralidad; para producir de este modo un extracto de alergeno despigmentado.
PE2021001195A 2019-01-17 2019-03-26 Metodos para purificar un extracto de alergeno PE20212105A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP19382030 2019-01-17
PCT/EP2019/057647 WO2020147985A1 (en) 2019-01-17 2019-03-26 Methods of purifying an allergen extract

Publications (1)

Publication Number Publication Date
PE20212105A1 true PE20212105A1 (es) 2021-11-04

Family

ID=65279503

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2021001195A PE20212105A1 (es) 2019-01-17 2019-03-26 Metodos para purificar un extracto de alergeno

Country Status (17)

Country Link
US (1) US20220110983A1 (es)
EP (1) EP3911343A1 (es)
JP (1) JP2022523647A (es)
CN (1) CN113825518A (es)
AU (1) AU2019422413A1 (es)
BR (1) BR112021014064A2 (es)
CA (1) CA3126499A1 (es)
CL (1) CL2021001889A1 (es)
CO (1) CO2021010606A2 (es)
CR (1) CR20210432A (es)
EC (1) ECSP21060381A (es)
IL (1) IL284901A (es)
JO (1) JOP20210197A1 (es)
MX (1) MX2021008665A (es)
PE (1) PE20212105A1 (es)
UA (1) UA128640C2 (es)
WO (1) WO2020147985A1 (es)

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0083497A3 (en) * 1982-01-06 1985-11-06 Beecham Group Plc Process for preparing modified allergens, their use in treating allergic conditions
CA2112913A1 (en) * 1991-07-12 1993-01-21 Irwin J. Griffith Allergenic proteins and peptides from japanese cedar pollen
JP3124344B2 (ja) * 1991-11-06 2001-01-15 フマキラー株式会社 重合ダニアレルゲン
JP3397791B2 (ja) * 1992-09-21 2003-04-21 ラボラトリオス レティ ソシエダッド アノニマ アレルゲンとして活性なタンパク質を含有する水性エキスの精製方法，この方法で得られるエキスならびにそれらの使用
AU675629B2 (en) 1992-09-21 1997-02-13 Laboratorios Leti S.A. A process for the purification of aqueous extracts containing allergenically active proteins, extracts obtainable according to this process as well as their use
CA2495825C (en) * 2002-08-19 2015-03-17 Merck Patent Gesellschaft Mit Beschraenkter Haftung Variants of the major allergen phl p 1 from timothy grass
PL1610820T5 (pl) * 2003-04-04 2014-01-31 Genentech Inc Preparaty zawierające wysokoskoncentrowane przeciwciała i białka
ES2395093T3 (es) * 2010-02-12 2014-12-22 Laboratorios Leti, S.L. Proceso para producir un extracto de alérgenos
FI20115374A0 (fi) * 2011-04-18 2011-04-18 Teknologian Tutkimuskeskus Vtt Oy Uudet hypoallergeenit
CN102552900A (zh) * 2011-12-21 2012-07-11 北京新华联协和药业有限责任公司 蒿属花粉变应原疫苗及其制备方法和应用
CN103966292A (zh) * 2013-01-31 2014-08-06 中国食品发酵工业研究院 一种过敏原部分消除的适度水解酪蛋白肽工业化制造方法及其应用
ES2503516B1 (es) * 2013-04-03 2015-09-09 Inmunotek, S.L. Complejo inmunogénico para vacunación y método de obtención

Also Published As

Publication number Publication date
AU2019422413A1 (en) 2021-08-26
JP2022523647A (ja) 2022-04-26
CN113825518A (zh) 2021-12-21
JOP20210197A1 (ar) 2023-01-30
ECSP21060381A (es) 2021-11-18
EP3911343A1 (en) 2021-11-24
UA128640C2 (uk) 2024-09-11
CR20210432A (es) 2022-01-05
WO2020147985A1 (en) 2020-07-23
MX2021008665A (es) 2021-10-26
CA3126499A1 (en) 2020-07-23
CL2021001889A1 (es) 2022-01-21
BR112021014064A2 (pt) 2021-09-21
CO2021010606A2 (es) 2021-10-29
IL284901A (en) 2021-08-31
US20220110983A1 (en) 2022-04-14

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