EP0083497A3 - Process for preparing modified allergens, their use in treating allergic conditions - Google Patents

Process for preparing modified allergens, their use in treating allergic conditions Download PDF

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Publication number
EP0083497A3
EP0083497A3 EP82306883A EP82306883A EP0083497A3 EP 0083497 A3 EP0083497 A3 EP 0083497A3 EP 82306883 A EP82306883 A EP 82306883A EP 82306883 A EP82306883 A EP 82306883A EP 0083497 A3 EP0083497 A3 EP 0083497A3
Authority
EP
European Patent Office
Prior art keywords
allergic conditions
treating allergic
preparing modified
modified allergens
allergen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP82306883A
Other languages
German (de)
French (fr)
Other versions
EP0083497A2 (en
Inventor
David Martin Moran
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Publication of EP0083497A2 publication Critical patent/EP0083497A2/en
Publication of EP0083497A3 publication Critical patent/EP0083497A3/en
Withdrawn legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/35—Allergens

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

A process for preparing a modified allergen comprises protecting a substantial proportion of the allergenic sites, reacting the allergen so protected with a cross-linking agent to give a linked product of substantially enhanced molecu­ lar weight distribution, and then deprotecting the linked product. The modified allergen produced by this process is useful in the treatment of allergic condition.
EP82306883A 1982-01-06 1982-12-23 Process for preparing modified allergens, their use in treating allergic conditions Withdrawn EP0083497A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8200329 1982-01-06
GB8200329 1982-01-06

Publications (2)

Publication Number Publication Date
EP0083497A2 EP0083497A2 (en) 1983-07-13
EP0083497A3 true EP0083497A3 (en) 1985-11-06

Family

ID=10527502

Family Applications (1)

Application Number Title Priority Date Filing Date
EP82306883A Withdrawn EP0083497A3 (en) 1982-01-06 1982-12-23 Process for preparing modified allergens, their use in treating allergic conditions

Country Status (6)

Country Link
EP (1) EP0083497A3 (en)
JP (1) JPS58126816A (en)
AU (1) AU1001083A (en)
ES (1) ES8402159A1 (en)
NZ (1) NZ202950A (en)
ZA (1) ZA8333B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5091318A (en) * 1990-04-13 1992-02-25 Abbott Laboratories Binding of allergens to a solid phase
AUPM307793A0 (en) * 1993-12-22 1994-01-20 Holt, Patrick G Professor Prophylaxis of allergic disease
US9884111B2 (en) * 2010-02-12 2018-02-06 Laboratorios Leti, S.L. Process for producing an allergen extract
PE20212105A1 (en) * 2019-01-17 2021-11-04 Leti Pharma S L METHODS TO PURIFY AN ALLERGEN EXTRACT

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1282163A (en) * 1969-08-06 1972-07-19 Beecham Group Ltd Modified allergens and a process for their preparation
US3761585A (en) * 1971-04-05 1973-09-25 Beecham Group Ltd Vaccines containing modified allergenic material
FR2437837A1 (en) * 1978-10-04 1980-04-30 Univ Johns Hopkins PROCESS FOR THE PREPARATION OF AN ALLERGEN TREATED WITH AN ALDEHYDE, PRODUCT OBTAINED AND ITS THERAPEUTIC APPLICATION

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1282163A (en) * 1969-08-06 1972-07-19 Beecham Group Ltd Modified allergens and a process for their preparation
US3761585A (en) * 1971-04-05 1973-09-25 Beecham Group Ltd Vaccines containing modified allergenic material
FR2437837A1 (en) * 1978-10-04 1980-04-30 Univ Johns Hopkins PROCESS FOR THE PREPARATION OF AN ALLERGEN TREATED WITH AN ALDEHYDE, PRODUCT OBTAINED AND ITS THERAPEUTIC APPLICATION

Also Published As

Publication number Publication date
ES518809A0 (en) 1984-02-01
EP0083497A2 (en) 1983-07-13
ZA8333B (en) 1983-10-26
ES8402159A1 (en) 1984-02-01
AU1001083A (en) 1983-07-14
NZ202950A (en) 1985-09-13
JPS58126816A (en) 1983-07-28

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

AK Designated contracting states

Designated state(s): BE CH DE FR GB IT LI NL SE

17P Request for examination filed

Effective date: 19840111

PUAL Search report despatched

Free format text: ORIGINAL CODE: 0009013

AK Designated contracting states

Designated state(s): BE CH DE FR GB IT LI NL SE

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 19860701

RIN1 Information on inventor provided before grant (corrected)

Inventor name: MORAN, DAVID MARTIN