PE20180780A1 - Composicion y productos que comprenden celulas senescentes para su uso en la regeneracion de tejidos - Google Patents

Composicion y productos que comprenden celulas senescentes para su uso en la regeneracion de tejidos

Info

Publication number
PE20180780A1
PE20180780A1 PE2018000256A PE2018000256A PE20180780A1 PE 20180780 A1 PE20180780 A1 PE 20180780A1 PE 2018000256 A PE2018000256 A PE 2018000256A PE 2018000256 A PE2018000256 A PE 2018000256A PE 20180780 A1 PE20180780 A1 PE 20180780A1
Authority
PE
Peru
Prior art keywords
products
regeneration
senescent cells
tissues
composition
Prior art date
Application number
PE2018000256A
Other languages
English (en)
Inventor
Martin Funk
Original Assignee
Qrskin Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Qrskin Gmbh filed Critical Qrskin Gmbh
Publication of PE20180780A1 publication Critical patent/PE20180780A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/40—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing ingredients of undetermined constitution or reaction products thereof, e.g. plant or animal extracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0057—Ingredients of undetermined constitution or reaction products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0028—Polypeptides; Proteins; Degradation products thereof
    • A61L26/0033—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0028—Polypeptides; Proteins; Degradation products thereof
    • A61L26/0047—Specific proteins or polypeptides not covered by groups A61L26/0033 - A61L26/0042
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061—Use of materials characterised by their function or physical properties
    • A61L26/0076—Sprayable compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061—Use of materials characterised by their function or physical properties
    • A61L26/008—Hydrogels or hydrocolloids

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Materials Engineering (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Botany (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Se refiere a celulas senescentes cultivadas in vitro, tales como celulas epiteliales, queratinocitos y/o fibroblastos, asi como a su uso en el tratamiento de regeneracion de tejidos, particularmente para el tratamiento de heridas tales como quemaduras o ulceras o el tratamiento de afecciones inflamatorias. Opcionalmente, los productos pueden usarse en combinacion con otros farmacos que incluyen agentes antimicrobianos o antidiabeticos
PE2018000256A 2015-08-21 2016-08-11 Composicion y productos que comprenden celulas senescentes para su uso en la regeneracion de tejidos PE20180780A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP15182070.1A EP3132809A1 (en) 2015-08-21 2015-08-21 Composition and products comprising senescent cells for use in tissue regeneration

Publications (1)

Publication Number Publication Date
PE20180780A1 true PE20180780A1 (es) 2018-05-07

Family

ID=54007554

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2018000256A PE20180780A1 (es) 2015-08-21 2016-08-11 Composicion y productos que comprenden celulas senescentes para su uso en la regeneracion de tejidos

Country Status (13)

Country Link
US (1) US10869900B2 (es)
EP (2) EP3132809A1 (es)
CN (1) CN107921169B (es)
BR (1) BR112018003311B1 (es)
CA (1) CA2996235C (es)
CL (1) CL2018000413A1 (es)
CO (1) CO2018001421A2 (es)
DK (1) DK3325025T3 (es)
EC (1) ECSP18012793A (es)
ES (1) ES2781334T3 (es)
MX (1) MX2018001827A (es)
PE (1) PE20180780A1 (es)
WO (1) WO2017032614A1 (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3490476A4 (en) * 2016-08-01 2020-03-25 Drexel University COMPOSITIONS AND METHODS FOR THE TREATMENT OF SKIN DISORDERS
US20200390854A1 (en) * 2017-03-23 2020-12-17 The Regents Of The University Of California Stimulation of hair growth by senescent cells and senescence associated secretory phenotype
CN107875171A (zh) * 2017-12-08 2018-04-06 深圳市莱利赛生物科技有限公司 一种脐带间充质干细胞药物在促进皮肤伤口愈合中的应用
KR102014467B1 (ko) * 2017-12-14 2019-08-26 (주)녹십자웰빙 아토피성 피부염, 탈모, 상처 또는 피부 주름의 개선용 화장료 조성물 및 약학 조성물
EP3764795A4 (en) * 2018-03-13 2022-05-11 The Board Of Trustees Of The Leland Stanford Junior University TRANSIENT CELLULAR REPROGRAMMING TO REVERSE CELL AGING
CN110484509B (zh) * 2019-08-14 2021-07-02 广东医科大学 一种IL1α启动子驱动荧光蛋白表达的永生化SASP细胞模型
CA3168454A1 (en) 2020-02-25 2021-09-02 David K. Rosen Compositions and methods for stimulating hair growth
CN111297905B (zh) * 2020-03-18 2022-11-04 四川大学华西医院 一种基于皮肤前体细胞的提取物及其制备方法和用途
US11987787B2 (en) 2020-07-22 2024-05-21 AVITA Medical Americas, LLC Devices, methods, and kits for preparing a cell suspension
WO2022187391A1 (en) * 2021-03-02 2022-09-09 Agex Therapeutics, Inc. Methods and compositions used to modify chromatin architecture to regulate phenotype in aging and cancer
CN113144221B (zh) * 2021-03-17 2022-11-15 北昊干细胞与再生医学研究院有限公司 外泌体制剂及其制备方法和应用
CN113667632B (zh) * 2021-09-14 2023-10-17 上海艾济生物科技有限公司 细胞培养基添加剂、细胞培养基及细胞体外扩增的方法
WO2023235511A1 (en) * 2022-06-01 2023-12-07 Sens Research Foundation Targeted elimination of senescent cells by gamma-delta t cells
WO2024104577A1 (en) 2022-11-16 2024-05-23 Evomedis Gmbh Cells being highly enriched in sasp factors, and composition comprising said cells

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0615545B1 (en) 1991-11-20 2000-05-17 N.V. Innogenetics S.A. Lysates derived from keratinocytes for use as wound healing substances
ATE206583T1 (de) 1994-11-09 2001-10-15 Celadon Science Llc Wundbesserungsverband und verfahren zur dessen konservierung
US5972332A (en) * 1997-04-16 1999-10-26 The Regents Of The University Of Michigan Wound treatment with keratinocytes on a solid support enclosed in a porous material
US7144729B2 (en) 2000-09-01 2006-12-05 Dfb Pharmaceuticals, Inc. Methods and compositions for tissue regeneration
US6673603B2 (en) 2000-09-01 2004-01-06 Modex Therapeutiques, S.A. Cell paste comprising keratinocytes and fibroblasts
DE10116362A1 (de) 2001-04-02 2002-10-10 Biotissue Technologies Ag Zwei-Komponenten Zusammensetzungen zur in situ Herstellung v. Fibroblasten und Keratinozyten umfassenden Zelltransplantaten
DE10151296A1 (de) 2001-10-17 2003-04-30 Boehringer Ingelheim Pharma Keratinozyten verwendbar als biologisch aktive Substanz bei der Behandlung von Wunden
GB2402882B (en) * 2003-06-20 2007-03-28 Johnson & Johnson Medical Ltd Antioxidant wound dressing materials
WO2005013885A2 (en) * 2003-08-07 2005-02-17 Healor Ltd. Pharmaceutical compositions and methods for accelerating wound healing
US20070258958A1 (en) 2006-02-14 2007-11-08 Reliance Life Sciences Private Limited Interactive wound cover
GB201004072D0 (en) 2010-03-11 2010-04-28 Turzi Antoine Process, tube and device for the preparation of wound healant composition
US20150024008A1 (en) * 2011-11-21 2015-01-22 The University Of Chicago Methods and Compositions Involving Induced Senescent Cells for Cancer Treatment

Also Published As

Publication number Publication date
CL2018000413A1 (es) 2018-06-01
BR112018003311B1 (pt) 2022-04-26
US10869900B2 (en) 2020-12-22
US20180360889A1 (en) 2018-12-20
CA2996235A1 (en) 2017-03-02
MX2018001827A (es) 2018-11-09
EP3325025B1 (en) 2020-01-08
ES2781334T3 (es) 2020-09-01
EP3325025A1 (en) 2018-05-30
CO2018001421A2 (es) 2018-04-30
DK3325025T3 (da) 2020-03-16
CA2996235C (en) 2022-10-25
CN107921169A (zh) 2018-04-17
ECSP18012793A (es) 2018-06-30
BR112018003311A2 (pt) 2018-09-18
EP3132809A1 (en) 2017-02-22
CN107921169B (zh) 2021-09-07
WO2017032614A1 (en) 2017-03-02

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