ECSP18012793A - Composición y productos que comprenden células senescentes para su uso en la regeneración de tejidos - Google Patents
Composición y productos que comprenden células senescentes para su uso en la regeneración de tejidosInfo
- Publication number
- ECSP18012793A ECSP18012793A ECIEPI201812793A ECPI201812793A ECSP18012793A EC SP18012793 A ECSP18012793 A EC SP18012793A EC IEPI201812793 A ECIEPI201812793 A EC IEPI201812793A EC PI201812793 A ECPI201812793 A EC PI201812793A EC SP18012793 A ECSP18012793 A EC SP18012793A
- Authority
- EC
- Ecuador
- Prior art keywords
- tissue regeneration
- senescent cells
- composition
- products including
- treatment
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/40—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing ingredients of undetermined constitution or reaction products thereof, e.g. plant or animal extracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0057—Ingredients of undetermined constitution or reaction products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
- A61L26/0028—Polypeptides; Proteins; Degradation products thereof
- A61L26/0033—Collagen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
- A61L26/0028—Polypeptides; Proteins; Degradation products thereof
- A61L26/0047—Specific proteins or polypeptides not covered by groups A61L26/0033 - A61L26/0042
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0061—Use of materials characterised by their function or physical properties
- A61L26/0076—Sprayable compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0061—Use of materials characterised by their function or physical properties
- A61L26/008—Hydrogels or hydrocolloids
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Zoology (AREA)
- Cell Biology (AREA)
- Materials Engineering (AREA)
- Dermatology (AREA)
- Developmental Biology & Embryology (AREA)
- Virology (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Botany (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Materials For Medical Uses (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
La presente invención se refiere a células senescentes cultivadas in vitro, tales como células epiteliales, queratinocitos y/o fibroblastos, así como a su uso en el tratamiento de regeneración de tejidos, particularmente para el tratamiento de heridas tales como quemaduras o úlceras o el tratamiento de afecciones inflamatorias. Opcionalmente, los productos pueden usarse en combinación con otros fármacos que incluyen agentes antimicrobianos o antidiabéticos.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP15182070.1A EP3132809A1 (en) | 2015-08-21 | 2015-08-21 | Composition and products comprising senescent cells for use in tissue regeneration |
Publications (1)
Publication Number | Publication Date |
---|---|
ECSP18012793A true ECSP18012793A (es) | 2018-06-30 |
Family
ID=54007554
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ECIEPI201812793A ECSP18012793A (es) | 2015-08-21 | 2018-02-20 | Composición y productos que comprenden células senescentes para su uso en la regeneración de tejidos |
Country Status (13)
Country | Link |
---|---|
US (1) | US10869900B2 (es) |
EP (2) | EP3132809A1 (es) |
CN (1) | CN107921169B (es) |
BR (1) | BR112018003311B1 (es) |
CA (1) | CA2996235C (es) |
CL (1) | CL2018000413A1 (es) |
CO (1) | CO2018001421A2 (es) |
DK (1) | DK3325025T3 (es) |
EC (1) | ECSP18012793A (es) |
ES (1) | ES2781334T3 (es) |
MX (1) | MX2018001827A (es) |
PE (1) | PE20180780A1 (es) |
WO (1) | WO2017032614A1 (es) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2018026750A1 (en) * | 2016-08-01 | 2018-02-08 | Drexel University | Devices and methods for treatment of skin conditions |
JP2020514395A (ja) * | 2017-03-23 | 2020-05-21 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 老化細胞および細胞老化関連分泌形質による発毛の刺激 |
CN107875171A (zh) * | 2017-12-08 | 2018-04-06 | 深圳市莱利赛生物科技有限公司 | 一种脐带间充质干细胞药物在促进皮肤伤口愈合中的应用 |
KR102014467B1 (ko) * | 2017-12-14 | 2019-08-26 | (주)녹십자웰빙 | 아토피성 피부염, 탈모, 상처 또는 피부 주름의 개선용 화장료 조성물 및 약학 조성물 |
CA3093823A1 (en) * | 2018-03-13 | 2019-09-19 | The Board Of Trustees Of The Leland Stanford Junior University | Transient cellular reprogramming for reversal of cell aging |
CN110484509B (zh) * | 2019-08-14 | 2021-07-02 | 广东医科大学 | 一种IL1α启动子驱动荧光蛋白表达的永生化SASP细胞模型 |
KR102563166B1 (ko) | 2020-02-25 | 2023-08-07 | 앰플리피카 인코포레이티드 | 모발 성장 촉진용 조성물 및 방법 |
CN111297905B (zh) * | 2020-03-18 | 2022-11-04 | 四川大学华西医院 | 一种基于皮肤前体细胞的提取物及其制备方法和用途 |
US11987787B2 (en) | 2020-07-22 | 2024-05-21 | AVITA Medical Americas, LLC | Devices, methods, and kits for preparing a cell suspension |
CA3212381A1 (en) * | 2021-03-02 | 2022-09-09 | Reverse Bioengineering, Inc. | Methods and compositions used to modify chromatin architecture to regulate phenotype in aging and cancer |
CN113144221B (zh) * | 2021-03-17 | 2022-11-15 | 北昊干细胞与再生医学研究院有限公司 | 外泌体制剂及其制备方法和应用 |
CN113667632B (zh) * | 2021-09-14 | 2023-10-17 | 上海艾济生物科技有限公司 | 细胞培养基添加剂、细胞培养基及细胞体外扩增的方法 |
WO2023235511A1 (en) * | 2022-06-01 | 2023-12-07 | Sens Research Foundation | Targeted elimination of senescent cells by gamma-delta t cells |
WO2024104577A1 (en) * | 2022-11-16 | 2024-05-23 | Evomedis Gmbh | Cells being highly enriched in sasp factors, and composition comprising said cells |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0970701B1 (en) | 1991-11-20 | 2005-10-26 | Innogenetics N.V. | Pellets derived from keratinocytes for use as wound healing substances |
JPH10509610A (ja) | 1994-11-09 | 1998-09-22 | クリ・ハークチ,ワリド | 創傷修復用包帯およびそれらの保存法 |
US5972332A (en) * | 1997-04-16 | 1999-10-26 | The Regents Of The University Of Michigan | Wound treatment with keratinocytes on a solid support enclosed in a porous material |
US6673603B2 (en) | 2000-09-01 | 2004-01-06 | Modex Therapeutiques, S.A. | Cell paste comprising keratinocytes and fibroblasts |
US7144729B2 (en) * | 2000-09-01 | 2006-12-05 | Dfb Pharmaceuticals, Inc. | Methods and compositions for tissue regeneration |
DE10116362A1 (de) | 2001-04-02 | 2002-10-10 | Biotissue Technologies Ag | Zwei-Komponenten Zusammensetzungen zur in situ Herstellung v. Fibroblasten und Keratinozyten umfassenden Zelltransplantaten |
DE10151296A1 (de) | 2001-10-17 | 2003-04-30 | Boehringer Ingelheim Pharma | Keratinozyten verwendbar als biologisch aktive Substanz bei der Behandlung von Wunden |
GB2402882B (en) * | 2003-06-20 | 2007-03-28 | Johnson & Johnson Medical Ltd | Antioxidant wound dressing materials |
CN102120031B (zh) * | 2003-08-07 | 2012-12-05 | 希尔洛有限公司 | 用于加速伤口愈合的药物组合物和方法 |
US20070258958A1 (en) | 2006-02-14 | 2007-11-08 | Reliance Life Sciences Private Limited | Interactive wound cover |
GB201004072D0 (en) * | 2010-03-11 | 2010-04-28 | Turzi Antoine | Process, tube and device for the preparation of wound healant composition |
WO2013078392A1 (en) * | 2011-11-21 | 2013-05-30 | The University Of Chicago | Methods and compositions involving induced senescent cells for cancer treatment |
-
2015
- 2015-08-21 EP EP15182070.1A patent/EP3132809A1/en not_active Withdrawn
-
2016
- 2016-08-11 US US15/752,765 patent/US10869900B2/en active Active
- 2016-08-11 CA CA2996235A patent/CA2996235C/en active Active
- 2016-08-11 CN CN201680048346.6A patent/CN107921169B/zh active Active
- 2016-08-11 WO PCT/EP2016/069189 patent/WO2017032614A1/en active Application Filing
- 2016-08-11 PE PE2018000256A patent/PE20180780A1/es unknown
- 2016-08-11 ES ES16753883T patent/ES2781334T3/es active Active
- 2016-08-11 MX MX2018001827A patent/MX2018001827A/es active IP Right Grant
- 2016-08-11 BR BR112018003311-1A patent/BR112018003311B1/pt active IP Right Grant
- 2016-08-11 EP EP16753883.4A patent/EP3325025B1/en active Active
- 2016-08-11 DK DK16753883.4T patent/DK3325025T3/da active
-
2018
- 2018-02-13 CO CONC2018/0001421A patent/CO2018001421A2/es unknown
- 2018-02-15 CL CL2018000413A patent/CL2018000413A1/es unknown
- 2018-02-20 EC ECIEPI201812793A patent/ECSP18012793A/es unknown
Also Published As
Publication number | Publication date |
---|---|
PE20180780A1 (es) | 2018-05-07 |
CA2996235A1 (en) | 2017-03-02 |
US20180360889A1 (en) | 2018-12-20 |
BR112018003311B1 (pt) | 2022-04-26 |
DK3325025T3 (da) | 2020-03-16 |
US10869900B2 (en) | 2020-12-22 |
EP3325025A1 (en) | 2018-05-30 |
CA2996235C (en) | 2022-10-25 |
CN107921169B (zh) | 2021-09-07 |
EP3325025B1 (en) | 2020-01-08 |
WO2017032614A1 (en) | 2017-03-02 |
CL2018000413A1 (es) | 2018-06-01 |
BR112018003311A2 (pt) | 2018-09-18 |
MX2018001827A (es) | 2018-11-09 |
ES2781334T3 (es) | 2020-09-01 |
CO2018001421A2 (es) | 2018-04-30 |
CN107921169A (zh) | 2018-04-17 |
EP3132809A1 (en) | 2017-02-22 |
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