PE20170776A1 - Nuevos anticuerpos anti-mfi2 y metodos de uso - Google Patents

Nuevos anticuerpos anti-mfi2 y metodos de uso

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Publication number
PE20170776A1
PE20170776A1 PE2017000403A PE2017000403A PE20170776A1 PE 20170776 A1 PE20170776 A1 PE 20170776A1 PE 2017000403 A PE2017000403 A PE 2017000403A PE 2017000403 A PE2017000403 A PE 2017000403A PE 20170776 A1 PE20170776 A1 PE 20170776A1
Authority
PE
Peru
Prior art keywords
methods
new anti
antibody
mfi2
antibodies
Prior art date
Application number
PE2017000403A
Other languages
English (en)
Inventor
Samuel Williams
Laura Saunders
Holger Karsunky
Mandy Boontanrart
Original Assignee
Abbvie Stemcentrx Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbvie Stemcentrx Llc filed Critical Abbvie Stemcentrx Llc
Publication of PE20170776A1 publication Critical patent/PE20170776A1/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
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    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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    • C07K2317/00—Immunoglobulins specific features
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Abstract

Se refiere a anticuerpos que se unen a una celula que expresa MFI2 humano. Tambien se refiere a un acido nucleico, un vector de expresion, una celula huesped, un metodo de tratamiento y a un conjugado de droga-anticuerpo (ADC) de formula Ab-[L-D]n, donde Ab es dicho anticuerpo; L es un agente de union opcional; D es un farmaco y n es 1 a 20. Dicho anticuerpo es util en el tratamiento del cancer
PE2017000403A 2014-09-05 2015-09-04 Nuevos anticuerpos anti-mfi2 y metodos de uso PE20170776A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462046610P 2014-09-05 2014-09-05
US201562203836P 2015-08-11 2015-08-11

Publications (1)

Publication Number Publication Date
PE20170776A1 true PE20170776A1 (es) 2017-07-04

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PE2017000403A PE20170776A1 (es) 2014-09-05 2015-09-04 Nuevos anticuerpos anti-mfi2 y metodos de uso

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Country Link
US (1) US10428156B2 (es)
EP (1) EP3189079A4 (es)
JP (1) JP2017535246A (es)
KR (1) KR20170045351A (es)
CN (1) CN107001454A (es)
AU (1) AU2015311743A1 (es)
BR (1) BR112017004444A2 (es)
CA (1) CA2959705A1 (es)
CL (2) CL2017000506A1 (es)
CO (1) CO2017003005A2 (es)
CR (1) CR20170117A (es)
DO (1) DOP2017000052A (es)
EA (1) EA201790529A1 (es)
IL (1) IL250825A0 (es)
MA (1) MA40612A (es)
MX (1) MX2017002862A (es)
PE (1) PE20170776A1 (es)
PH (1) PH12017500406A1 (es)
SG (1) SG11201701650PA (es)
TW (1) TW201617368A (es)
WO (1) WO2016037119A1 (es)
ZA (1) ZA201701674B (es)

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MX2018012433A (es) 2016-04-15 2019-03-01 Macrogenics Inc Moleculas de union b7-h3 novedosas, conjugados anticuerpo-farmaco de los mismos y metodos de uso de los mismos.
US11327078B2 (en) * 2018-02-27 2022-05-10 Eisai R&D Management Co., Ltd. Monoclonal antibody against APOA4, immunological measurement method, and kit for measurement
CN112105343B (zh) * 2018-03-07 2024-07-30 辉瑞公司 抗-pd-1抗体组合物
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