PE20151558A1 - Inhibidores tripeptidicos de la epoxicetona proteasa - Google Patents

Inhibidores tripeptidicos de la epoxicetona proteasa

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Publication number
PE20151558A1
PE20151558A1 PE2015001916A PE2015001916A PE20151558A1 PE 20151558 A1 PE20151558 A1 PE 20151558A1 PE 2015001916 A PE2015001916 A PE 2015001916A PE 2015001916 A PE2015001916 A PE 2015001916A PE 20151558 A1 PE20151558 A1 PE 20151558A1
Authority
PE
Peru
Prior art keywords
protease
epoxycetone
inhibitors
tripeptide inhibitors
refers
Prior art date
Application number
PE2015001916A
Other languages
English (en)
Inventor
Dustin Mcminn
Henry Johnson
Simeon Bowers
David C Moebius
Original Assignee
Onyx Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=51581125&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20151558(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Onyx Therapeutics Inc filed Critical Onyx Therapeutics Inc
Publication of PE20151558A1 publication Critical patent/PE20151558A1/es

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    • C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
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    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
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  • Obesity (AREA)

Abstract

SE REFIERE A COMPUESTOS TRIPEPTIDICOS DE EPOXI CETONA DE FORMULA (X) Y SALES FARMACEUTICAMENTE ACEPTABLES, DONDE R1, R2, R3, R4, K, E, m, n, p Y q SON COMO SE DEFINEN EN LA DESCRIPCION. TAMBIEN SE REFIERE A UNA COMPOSICION FARMACEUTICA. DICHOS COMPUESTOS SON INHIBIDORES DE PROTEASA SIENDO UTILES EN EL TRATAMIENTO DE ENFERMEDADES AUTOINMUNES Y ENFERMEDADES NEURODEGENERATIVAS
PE2015001916A 2013-03-14 2014-03-14 Inhibidores tripeptidicos de la epoxicetona proteasa PE20151558A1 (es)

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BR112015023298A2 (pt) 2017-07-18
MX366200B (es) 2019-07-02
IL241170A0 (en) 2015-11-30
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AU2014240129A1 (en) 2015-09-24
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US20160368946A1 (en) 2016-12-22
HUE034769T2 (en) 2018-02-28
PT2970224T (pt) 2017-11-14
US20140336106A1 (en) 2014-11-13
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US9434761B2 (en) 2016-09-06
SI2970224T1 (sl) 2017-12-29
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US11078233B2 (en) 2021-08-03
CN105143212B (zh) 2018-02-23
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