PE20120794A1 - Monohidrato cristalino de 3-{(s)-1-[4-(1-ciclopropil-2-oxo-1,2-dihidropiridin-4-il)fenil]etil}-(s)-6-(2-hidroxi-2-metilpropil)-6-fenil-[1,3]oxazinan-2-ona - Google Patents
Monohidrato cristalino de 3-{(s)-1-[4-(1-ciclopropil-2-oxo-1,2-dihidropiridin-4-il)fenil]etil}-(s)-6-(2-hidroxi-2-metilpropil)-6-fenil-[1,3]oxazinan-2-onaInfo
- Publication number
- PE20120794A1 PE20120794A1 PE2011001866A PE2011001866A PE20120794A1 PE 20120794 A1 PE20120794 A1 PE 20120794A1 PE 2011001866 A PE2011001866 A PE 2011001866A PE 2011001866 A PE2011001866 A PE 2011001866A PE 20120794 A1 PE20120794 A1 PE 20120794A1
- Authority
- PE
- Peru
- Prior art keywords
- phenyl
- ethyl
- oxazinan
- methylpropyl
- oxo
- Prior art date
Links
- QUPDWYMUPZLYJZ-UHFFFAOYSA-N ethyl Chemical compound C[CH2] QUPDWYMUPZLYJZ-UHFFFAOYSA-N 0.000 title abstract 5
- -1 2-HYDROXY- 2-METHYLPROPYL Chemical class 0.000 title abstract 4
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical compound [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 title abstract 4
- 150000004682 monohydrates Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- WCYWZMWISLQXQU-UHFFFAOYSA-N methyl Chemical class [CH3] WCYWZMWISLQXQU-UHFFFAOYSA-N 0.000 abstract 2
- 101710088194 Dehydrogenase Proteins 0.000 abstract 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- FVSKHRXBFJPNKK-UHFFFAOYSA-N propionitrile Chemical compound CCC#N FVSKHRXBFJPNKK-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2009/002653 WO2009134400A1 (en) | 2008-05-01 | 2009-04-30 | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| PCT/US2009/004261 WO2010011314A1 (en) | 2008-07-25 | 2009-07-23 | Cyclic inhibitors of 11 beta-hydroxysteroid dehydrogenase 1 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20120794A1 true PE20120794A1 (es) | 2012-07-26 |
Family
ID=45478607
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2011001866A PE20120794A1 (es) | 2009-04-30 | 2010-04-30 | Monohidrato cristalino de 3-{(s)-1-[4-(1-ciclopropil-2-oxo-1,2-dihidropiridin-4-il)fenil]etil}-(s)-6-(2-hidroxi-2-metilpropil)-6-fenil-[1,3]oxazinan-2-ona |
Country Status (9)
| Country | Link |
|---|---|
| JP (1) | JP5784006B2 (https=) |
| AP (1) | AP2011005948A0 (https=) |
| CL (1) | CL2014001815A1 (https=) |
| CO (1) | CO6501139A2 (https=) |
| IL (1) | IL215249A (https=) |
| MX (1) | MX2011011503A (https=) |
| NZ (1) | NZ595473A (https=) |
| PE (1) | PE20120794A1 (https=) |
| TN (1) | TN2010000467A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2744946A1 (en) * | 2009-02-04 | 2010-08-12 | Boehringer Ingelheim International Gmbh | Cyclic inhibitors of 11.beta.-hydroxysteroid dehydrogenase 1 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2183228B1 (en) * | 2007-07-26 | 2014-08-20 | Vitae Pharmaceuticals, Inc. | CYCLIC INHIBITORS OF 11ß -HYDROXYSTERIOD DEHYDROGENASE 1 |
-
2010
- 2010-04-30 NZ NZ595473A patent/NZ595473A/en not_active IP Right Cessation
- 2010-04-30 PE PE2011001866A patent/PE20120794A1/es not_active Application Discontinuation
- 2010-04-30 AP AP2011005948A patent/AP2011005948A0/xx unknown
- 2010-04-30 JP JP2012508772A patent/JP5784006B2/ja active Active
- 2010-04-30 MX MX2011011503A patent/MX2011011503A/es active IP Right Grant
- 2010-10-14 TN TNP2010000467A patent/TN2010000467A1/fr unknown
-
2011
- 2011-09-20 IL IL215249A patent/IL215249A/en not_active IP Right Cessation
- 2011-10-05 CO CO11131281A patent/CO6501139A2/es not_active Application Discontinuation
-
2014
- 2014-07-08 CL CL2014001815A patent/CL2014001815A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CL2014001815A1 (es) | 2015-02-13 |
| AP2011005948A0 (en) | 2011-10-31 |
| NZ595473A (en) | 2014-01-31 |
| HK1169409A1 (en) | 2013-01-25 |
| JP2012525440A (ja) | 2012-10-22 |
| CO6501139A2 (es) | 2012-08-15 |
| IL215249A0 (en) | 2011-12-29 |
| MX2011011503A (es) | 2011-11-18 |
| IL215249A (en) | 2014-12-31 |
| JP5784006B2 (ja) | 2015-09-24 |
| TN2010000467A1 (en) | 2012-05-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant, registration | ||
| FD | Application declared void or lapsed |