NZ595473A - Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 - Google Patents

Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1

Info

Publication number
NZ595473A
NZ595473A NZ595473A NZ59547310A NZ595473A NZ 595473 A NZ595473 A NZ 595473A NZ 595473 A NZ595473 A NZ 595473A NZ 59547310 A NZ59547310 A NZ 59547310A NZ 595473 A NZ595473 A NZ 595473A
Authority
NZ
New Zealand
Prior art keywords
11beta
hydroxysteroid dehydrogenase
phenyl
cyclic inhibitors
oxazinan
Prior art date
Application number
NZ595473A
Inventor
Martin Schuele
Martin Renz
Zhenrong Xu
Original Assignee
Vitae Pharmaceuticals Inc
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=45478607&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NZ595473(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from PCT/US2009/002653 external-priority patent/WO2009134400A1/en
Priority claimed from PCT/US2009/004261 external-priority patent/WO2010011314A1/en
Application filed by Vitae Pharmaceuticals Inc, Boehringer Ingelheim Int filed Critical Vitae Pharmaceuticals Inc
Priority to NZ618741A priority Critical patent/NZ618741A/en
Priority claimed from PCT/US2010/033157 external-priority patent/WO2010127237A2/en
Publication of NZ595473A publication Critical patent/NZ595473A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)

Abstract

595473 Disclosed is a monohydrate of an oxodihydropyridine ethyl phenyl pyridine substituted [1,3]oxazinan-2-one compound of formula (Ip3). An example of compounds of formula (Ip3) is (S)-6-(2-hydroxy-2 -methylpropyl)-3-((S)-1-(4-(1-methyl-2-oxo-1,2 -dihydropyridin-4-yl)phenyl)ethyl)-6-phenyl-1,3-oxazinan-2-one. Also disclosed are pharmaceutical compositions of the novel compounds and methods for their use in the reduction or control of the production of Cortisol in a cell or the inhibition of the conversion of cortisone to Cortisol in a cell.
NZ595473A 2009-04-30 2010-04-30 Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 NZ595473A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
NZ618741A NZ618741A (en) 2009-04-30 2010-04-30 Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
PCT/US2009/002653 WO2009134400A1 (en) 2008-05-01 2009-04-30 Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
PCT/US2009/004261 WO2010011314A1 (en) 2008-07-25 2009-07-23 Cyclic inhibitors of 11 beta-hydroxysteroid dehydrogenase 1
PCT/US2010/033157 WO2010127237A2 (en) 2009-04-30 2010-04-30 Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1

Publications (1)

Publication Number Publication Date
NZ595473A true NZ595473A (en) 2014-01-31

Family

ID=45478607

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ595473A NZ595473A (en) 2009-04-30 2010-04-30 Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1

Country Status (10)

Country Link
JP (1) JP5784006B2 (en)
AP (1) AP2011005948A0 (en)
CL (1) CL2014001815A1 (en)
CO (1) CO6501139A2 (en)
HK (1) HK1169409A1 (en)
IL (1) IL215249A (en)
MX (1) MX2011011503A (en)
NZ (1) NZ595473A (en)
PE (1) PE20120794A1 (en)
TN (1) TN2010000467A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2393807B1 (en) * 2009-02-04 2013-08-14 Boehringer Ingelheim International GmbH Cyclic inhibitors of 11 -hydroxysteroid dehydrogenase 1

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5451611B2 (en) * 2007-07-26 2014-03-26 ヴァイティー ファーマシューティカルズ，インコーポレイテッド Cyclic inhibitor of 11β-hydroxysteroid dehydrogenase 1

Also Published As

Publication number Publication date
MX2011011503A (en) 2011-11-18
IL215249A (en) 2014-12-31
IL215249A0 (en) 2011-12-29
HK1169409A1 (en) 2013-01-25
CL2014001815A1 (en) 2015-02-13
JP2012525440A (en) 2012-10-22
AP2011005948A0 (en) 2011-10-31
TN2010000467A1 (en) 2012-05-24
JP5784006B2 (en) 2015-09-24
PE20120794A1 (en) 2012-07-26
CO6501139A2 (en) 2012-08-15

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Legal Events

Date Code Title Description
ERR Error or correction

Free format text: THE OWNER HAS BEEN CORRECTED TO 1197495, VITAE PHARMACEUTICALS, INC., 502 WEST OFFICE CENTER DRIVE, FORT WASHINGTON, PENNSYLVANIA 19034, US; 1365327, BOEHRINGER INGELHEIM INTERNATIONAL GMBH, BINGER STRASSE 173, D-55216 INGELHEIM AM RHEIN, DE

Effective date: 20131213

PSEA Patent sealed
RENW Renewal (renewal fees accepted)

Free format text: PATENT RENEWED FOR 3 YEARS UNTIL 30 APR 2017 BY DAVIES COLLISON CAVE

Effective date: 20140502

LAPS Patent lapsed