PE20091344A1 - Arilindenopirimidinas como antagonistas del receptor a2a de adenosina - Google Patents
Arilindenopirimidinas como antagonistas del receptor a2a de adenosinaInfo
- Publication number
- PE20091344A1 PE20091344A1 PE2008001819A PE2008001819A PE20091344A1 PE 20091344 A1 PE20091344 A1 PE 20091344A1 PE 2008001819 A PE2008001819 A PE 2008001819A PE 2008001819 A PE2008001819 A PE 2008001819A PE 20091344 A1 PE20091344 A1 PE 20091344A1
- Authority
- PE
- Peru
- Prior art keywords
- disease
- adenosine
- receptor
- arylindenopyrimidines
- antagonists
- Prior art date
Links
- 239000005557 antagonist Substances 0.000 title abstract 2
- 102000007471 Adenosine A2A receptor Human genes 0.000 title 1
- 108010085277 Adenosine A2A receptor Proteins 0.000 title 1
- 208000024827 Alzheimer disease Diseases 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 101150051188 Adora2a gene Proteins 0.000 abstract 1
- 206010003694 Atrophy Diseases 0.000 abstract 1
- 208000011990 Corticobasal Degeneration Diseases 0.000 abstract 1
- 208000023105 Huntington disease Diseases 0.000 abstract 1
- 208000018737 Parkinson disease Diseases 0.000 abstract 1
- 206010039966 Senile dementia Diseases 0.000 abstract 1
- 150000004677 hydrates Chemical class 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Addiction (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US98224707P | 2007-10-24 | 2007-10-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20091344A1 true PE20091344A1 (es) | 2009-09-24 |
Family
ID=40091927
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2008001819A PE20091344A1 (es) | 2007-10-24 | 2008-10-23 | Arilindenopirimidinas como antagonistas del receptor a2a de adenosina |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US8017614B2 (enExample) |
| EP (1) | EP2217575A1 (enExample) |
| JP (1) | JP2011500819A (enExample) |
| CN (1) | CN101835759A (enExample) |
| AR (1) | AR069009A1 (enExample) |
| AU (1) | AU2008317034A1 (enExample) |
| CL (1) | CL2008003131A1 (enExample) |
| PA (1) | PA8801501A1 (enExample) |
| PE (1) | PE20091344A1 (enExample) |
| TW (1) | TW200934493A (enExample) |
| UY (1) | UY31420A1 (enExample) |
| WO (1) | WO2009055308A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20110105540A1 (en) * | 2009-10-29 | 2011-05-05 | Jackson Paul F | 2-AMINO-9-[4-(4-METHOXY-PHENOXY)-PIPERIDIN-1-YL]-4-PHENYL-INDENO[1,2-D]PYRIMIDIN-5-ONE AND ITS USE AS A HIGHLY SELECTIVE ADENOSINE A2a RECEPTOR ANTAGONIST |
| GB2497476B (en) * | 2010-09-06 | 2018-01-10 | Guangzhou Inst Biomed & Health | Amide Compounds |
| AU2013251079B2 (en) | 2012-04-20 | 2017-03-23 | Ucb Pharma S.A. | Methods for treating Parkinson's disease |
| WO2020146795A1 (en) | 2019-01-11 | 2020-07-16 | Omeros Corporation | Methods and compositions for treating cancer |
| AU2023252914A1 (en) | 2022-04-13 | 2024-10-17 | Arcus Biosciences, Inc. | Combination therapy for treating trop-2 expressing cancers |
| US20250230168A1 (en) | 2023-12-22 | 2025-07-17 | Gilead Sciences, Inc. | Azaspiro wrn inhibitors |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040127510A1 (en) | 2002-04-16 | 2004-07-01 | Heintzelman Geoffrey R. | Arylindenopyridines and arylindenopyrimidines and related therapeutic and prophylactic methods |
| JP4725963B2 (ja) | 2003-10-03 | 2011-07-13 | オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド | アリールインデノピリジンおよびアリールインデノピリミジンならびにアデノシンＡ２ａ受容体アンタゴニストとしてのそれらの使用 |
-
2008
- 2008-10-17 JP JP2010531141A patent/JP2011500819A/ja not_active Withdrawn
- 2008-10-17 US US12/253,358 patent/US8017614B2/en not_active Expired - Fee Related
- 2008-10-17 CN CN200880112882A patent/CN101835759A/zh active Pending
- 2008-10-17 AU AU2008317034A patent/AU2008317034A1/en not_active Abandoned
- 2008-10-17 EP EP08841238A patent/EP2217575A1/en not_active Withdrawn
- 2008-10-17 WO PCT/US2008/080256 patent/WO2009055308A1/en not_active Ceased
- 2008-10-23 PA PA20088801501A patent/PA8801501A1/es unknown
- 2008-10-23 TW TW097140560A patent/TW200934493A/zh unknown
- 2008-10-23 AR ARP080104625A patent/AR069009A1/es not_active Application Discontinuation
- 2008-10-23 CL CL2008003131A patent/CL2008003131A1/es unknown
- 2008-10-23 PE PE2008001819A patent/PE20091344A1/es not_active Application Discontinuation
- 2008-10-24 UY UY31420A patent/UY31420A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PA8801501A1 (es) | 2009-05-15 |
| UY31420A1 (es) | 2009-04-30 |
| US20090111827A1 (en) | 2009-04-30 |
| CL2008003131A1 (es) | 2010-02-19 |
| JP2011500819A (ja) | 2011-01-06 |
| TW200934493A (en) | 2009-08-16 |
| US8017614B2 (en) | 2011-09-13 |
| WO2009055308A1 (en) | 2009-04-30 |
| AR069009A1 (es) | 2009-12-23 |
| AU2008317034A1 (en) | 2009-04-30 |
| CN101835759A (zh) | 2010-09-15 |
| EP2217575A1 (en) | 2010-08-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC | Refusal |