PA8801501A1 - ARILINDENOPIRIMIDINAS Y SU USO COMO ANTAGONISTAS DEL RECEPTOR A 2a DE ADENOSINA - Google Patents
ARILINDENOPIRIMIDINAS Y SU USO COMO ANTAGONISTAS DEL RECEPTOR A 2a DE ADENOSINAInfo
- Publication number
- PA8801501A1 PA8801501A1 PA20088801501A PA8801501A PA8801501A1 PA 8801501 A1 PA8801501 A1 PA 8801501A1 PA 20088801501 A PA20088801501 A PA 20088801501A PA 8801501 A PA8801501 A PA 8801501A PA 8801501 A1 PA8801501 A1 PA 8801501A1
- Authority
- PA
- Panama
- Prior art keywords
- arylindenopirimidines
- adenosine
- receiver antagonists
- antagonists
- adenosine receiver
- Prior art date
Links
- OIRDTQYFTABQOQ-KQYNXXCUSA-N adenosine Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O OIRDTQYFTABQOQ-KQYNXXCUSA-N 0.000 title 2
- 239000002126 C01EB10 - Adenosine Substances 0.000 title 1
- 229960005305 adenosine Drugs 0.000 title 1
- 239000005557 antagonist Substances 0.000 title 1
- 208000018737 Parkinson disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Addiction (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US98224707P | 2007-10-24 | 2007-10-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PA8801501A1 true PA8801501A1 (es) | 2009-05-15 |
Family
ID=40091927
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PA20088801501A PA8801501A1 (es) | 2007-10-24 | 2008-10-23 | ARILINDENOPIRIMIDINAS Y SU USO COMO ANTAGONISTAS DEL RECEPTOR A 2a DE ADENOSINA |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US8017614B2 (enExample) |
| EP (1) | EP2217575A1 (enExample) |
| JP (1) | JP2011500819A (enExample) |
| CN (1) | CN101835759A (enExample) |
| AR (1) | AR069009A1 (enExample) |
| AU (1) | AU2008317034A1 (enExample) |
| CL (1) | CL2008003131A1 (enExample) |
| PA (1) | PA8801501A1 (enExample) |
| PE (1) | PE20091344A1 (enExample) |
| TW (1) | TW200934493A (enExample) |
| UY (1) | UY31420A1 (enExample) |
| WO (1) | WO2009055308A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20110105540A1 (en) * | 2009-10-29 | 2011-05-05 | Jackson Paul F | 2-AMINO-9-[4-(4-METHOXY-PHENOXY)-PIPERIDIN-1-YL]-4-PHENYL-INDENO[1,2-D]PYRIMIDIN-5-ONE AND ITS USE AS A HIGHLY SELECTIVE ADENOSINE A2a RECEPTOR ANTAGONIST |
| GB2497476B (en) * | 2010-09-06 | 2018-01-10 | Guangzhou Inst Biomed & Health | Amide Compounds |
| AU2013251079B2 (en) | 2012-04-20 | 2017-03-23 | Ucb Pharma S.A. | Methods for treating Parkinson's disease |
| WO2020146795A1 (en) | 2019-01-11 | 2020-07-16 | Omeros Corporation | Methods and compositions for treating cancer |
| AU2023252914A1 (en) | 2022-04-13 | 2024-10-17 | Arcus Biosciences, Inc. | Combination therapy for treating trop-2 expressing cancers |
| US20250230168A1 (en) | 2023-12-22 | 2025-07-17 | Gilead Sciences, Inc. | Azaspiro wrn inhibitors |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040127510A1 (en) | 2002-04-16 | 2004-07-01 | Heintzelman Geoffrey R. | Arylindenopyridines and arylindenopyrimidines and related therapeutic and prophylactic methods |
| JP4725963B2 (ja) | 2003-10-03 | 2011-07-13 | オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド | アリールインデノピリジンおよびアリールインデノピリミジンならびにアデノシンＡ２ａ受容体アンタゴニストとしてのそれらの使用 |
-
2008
- 2008-10-17 JP JP2010531141A patent/JP2011500819A/ja not_active Withdrawn
- 2008-10-17 US US12/253,358 patent/US8017614B2/en not_active Expired - Fee Related
- 2008-10-17 CN CN200880112882A patent/CN101835759A/zh active Pending
- 2008-10-17 AU AU2008317034A patent/AU2008317034A1/en not_active Abandoned
- 2008-10-17 EP EP08841238A patent/EP2217575A1/en not_active Withdrawn
- 2008-10-17 WO PCT/US2008/080256 patent/WO2009055308A1/en not_active Ceased
- 2008-10-23 PA PA20088801501A patent/PA8801501A1/es unknown
- 2008-10-23 TW TW097140560A patent/TW200934493A/zh unknown
- 2008-10-23 AR ARP080104625A patent/AR069009A1/es not_active Application Discontinuation
- 2008-10-23 CL CL2008003131A patent/CL2008003131A1/es unknown
- 2008-10-23 PE PE2008001819A patent/PE20091344A1/es not_active Application Discontinuation
- 2008-10-24 UY UY31420A patent/UY31420A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| UY31420A1 (es) | 2009-04-30 |
| US20090111827A1 (en) | 2009-04-30 |
| CL2008003131A1 (es) | 2010-02-19 |
| JP2011500819A (ja) | 2011-01-06 |
| TW200934493A (en) | 2009-08-16 |
| US8017614B2 (en) | 2011-09-13 |
| WO2009055308A1 (en) | 2009-04-30 |
| PE20091344A1 (es) | 2009-09-24 |
| AR069009A1 (es) | 2009-12-23 |
| AU2008317034A1 (en) | 2009-04-30 |
| CN101835759A (zh) | 2010-09-15 |
| EP2217575A1 (en) | 2010-08-18 |
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