PE20080687A1 - Derivados de iminoimidazopiridina que tienen actividad antitrombotica - Google Patents
Derivados de iminoimidazopiridina que tienen actividad antitromboticaInfo
- Publication number
- PE20080687A1 PE20080687A1 PE2007000991A PE2007000991A PE20080687A1 PE 20080687 A1 PE20080687 A1 PE 20080687A1 PE 2007000991 A PE2007000991 A PE 2007000991A PE 2007000991 A PE2007000991 A PE 2007000991A PE 20080687 A1 PE20080687 A1 PE 20080687A1
- Authority
- PE
- Peru
- Prior art keywords
- alkyl
- iminoimidazopyridine
- iminoimidazo
- ethanone
- pyridin
- Prior art date
Links
- IPPXOQSUEICOSX-UHFFFAOYSA-N imidazo[4,5-b]pyridin-2-imine Chemical class C1=CC=NC2=NC(=N)N=C21 IPPXOQSUEICOSX-UHFFFAOYSA-N 0.000 title abstract 2
- 230000002785 anti-thrombosis Effects 0.000 title 1
- IKHGUXGNUITLKF-UHFFFAOYSA-N Acetaldehyde Chemical compound CC=O IKHGUXGNUITLKF-UHFFFAOYSA-N 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 101001098529 Homo sapiens Proteinase-activated receptor 1 Proteins 0.000 abstract 1
- 101000713169 Homo sapiens Solute carrier family 52, riboflavin transporter, member 2 Proteins 0.000 abstract 1
- 108091005804 Peptidases Proteins 0.000 abstract 1
- 239000004365 Protease Substances 0.000 abstract 1
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 abstract 1
- 102100036862 Solute carrier family 52, riboflavin transporter, member 2 Human genes 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 108020003175 receptors Proteins 0.000 abstract 1
- 102000005962 receptors Human genes 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Diabetes (AREA)
- Pulmonology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Pain & Pain Management (AREA)
- Obesity (AREA)
- Communicable Diseases (AREA)
- Endocrinology (AREA)
- Dermatology (AREA)
- Emergency Medicine (AREA)
- Psychiatry (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102006036023A DE102006036023A1 (de) | 2006-08-02 | 2006-08-02 | Imino-imidazo-pyridinderivate mit antithrombotischer Aktivität |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20080687A1 true PE20080687A1 (es) | 2008-07-24 |
Family
ID=38884850
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2007000991A PE20080687A1 (es) | 2006-08-02 | 2007-07-31 | Derivados de iminoimidazopiridina que tienen actividad antitrombotica |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US7863269B2 (https=) |
| EP (1) | EP2054412B1 (https=) |
| JP (1) | JP5149897B2 (https=) |
| KR (1) | KR20090129981A (https=) |
| CN (1) | CN101495478B (https=) |
| AR (1) | AR062158A1 (https=) |
| AT (1) | ATE450537T1 (https=) |
| AU (1) | AU2007280780B2 (https=) |
| BR (1) | BRPI0714599A2 (https=) |
| CA (1) | CA2663332C (https=) |
| CL (1) | CL2007002240A1 (https=) |
| DE (2) | DE102006036023A1 (https=) |
| DK (1) | DK2054412T3 (https=) |
| DO (1) | DOP2007000120A (https=) |
| ES (1) | ES2336044T3 (https=) |
| IL (1) | IL196789A (https=) |
| MX (1) | MX2009000408A (https=) |
| MY (1) | MY148611A (https=) |
| NO (1) | NO20090741L (https=) |
| PE (1) | PE20080687A1 (https=) |
| PT (1) | PT2054412E (https=) |
| TW (1) | TWI400240B (https=) |
| WO (1) | WO2008014888A2 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RS52264B (sr) * | 2008-02-05 | 2012-10-31 | Sanofi | Triazolopiridazini kao inhibitori par1, njihovo dobijanje i upotreba kao lekova |
| US20160040247A1 (en) | 2013-03-15 | 2016-02-11 | Fundació Institut De Recerca Biomèdica (Irb Barcelona) | Method for the diagnosis, prognosis, and tratment of cancer metastasis |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5124517B1 (https=) * | 1971-03-15 | 1976-07-24 | ||
| DE2221796A1 (de) | 1972-05-04 | 1973-11-15 | Kraemer Kg Wilhelm | Batteriebehaelter fuer stabbatterien |
| JPS60161986A (ja) * | 1983-12-24 | 1985-08-23 | Nippon Soda Co Ltd | イミダゾ（１，５−ａ）ピリジン−３−オン誘導体及びその製造方法 |
| US6063847A (en) * | 1997-11-25 | 2000-05-16 | Schering Corporation | Thrombin receptor antagonists |
| US7488742B2 (en) * | 2000-06-15 | 2009-02-10 | Schering Corporation | Thrombin receptor antagonists |
| EP1394152A4 (en) * | 2001-04-19 | 2005-02-02 | Eisai Co Ltd | 2-IMINOIMIDAZOLE DERIVATIVES (1) |
| BRPI0309309B8 (pt) | 2002-04-16 | 2021-05-25 | Merck Sharp & Dohme | antagonistas de receptor de trombina tricíclicos |
| CN100439336C (zh) | 2003-02-19 | 2008-12-03 | 卫材R&D管理有限公司 | 制备环状苯甲脒衍生物的方法 |
| DE10353205A1 (de) | 2003-11-13 | 2005-06-16 | Aventis Pharma Deutschland Gmbh | Ortho-substituierte Pentafluorsulfuranyl-Benzole, Verfahren zu ihrer Herstellung sowie ihre Verwendung als wertvolle Synthese-Zwischenstufen |
| US7317124B2 (en) * | 2003-11-13 | 2008-01-08 | Sanofi-Aventis Deutschland Gmbh | Ortho-substituted pentafluorosulfanylbenzenes, process for their preparation and their use as valuable synthetic intermediates |
-
2006
- 2006-08-02 DE DE102006036023A patent/DE102006036023A1/de not_active Withdrawn
-
2007
- 2007-07-18 WO PCT/EP2007/006360 patent/WO2008014888A2/de not_active Ceased
- 2007-07-18 ES ES07765222T patent/ES2336044T3/es active Active
- 2007-07-18 EP EP07765222A patent/EP2054412B1/de not_active Not-in-force
- 2007-07-18 MY MYPI20090170A patent/MY148611A/en unknown
- 2007-07-18 DE DE502007002219T patent/DE502007002219D1/de active Active
- 2007-07-18 CA CA2663332A patent/CA2663332C/en not_active Expired - Fee Related
- 2007-07-18 MX MX2009000408A patent/MX2009000408A/es active IP Right Grant
- 2007-07-18 BR BRPI0714599-3A patent/BRPI0714599A2/pt not_active IP Right Cessation
- 2007-07-18 CN CN2007800279925A patent/CN101495478B/zh not_active Expired - Fee Related
- 2007-07-18 JP JP2009522134A patent/JP5149897B2/ja not_active Expired - Fee Related
- 2007-07-18 KR KR1020097002137A patent/KR20090129981A/ko not_active Abandoned
- 2007-07-18 PT PT07765222T patent/PT2054412E/pt unknown
- 2007-07-18 AU AU2007280780A patent/AU2007280780B2/en not_active Ceased
- 2007-07-18 AT AT07765222T patent/ATE450537T1/de active
- 2007-07-18 DK DK07765222.0T patent/DK2054412T3/da active
- 2007-07-31 TW TW096127870A patent/TWI400240B/zh not_active IP Right Cessation
- 2007-07-31 AR ARP070103373A patent/AR062158A1/es not_active Application Discontinuation
- 2007-07-31 PE PE2007000991A patent/PE20080687A1/es not_active Application Discontinuation
- 2007-07-31 DO DO2007000120A patent/DOP2007000120A/es unknown
- 2007-08-01 CL CL200702240A patent/CL2007002240A1/es unknown
-
2009
- 2009-01-29 IL IL196789A patent/IL196789A/en not_active IP Right Cessation
- 2009-02-02 US US12/364,124 patent/US7863269B2/en not_active Expired - Fee Related
- 2009-02-16 NO NO20090741A patent/NO20090741L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| IL196789A (en) | 2012-07-31 |
| JP2009545542A (ja) | 2009-12-24 |
| DE502007002219D1 (de) | 2010-01-14 |
| DE102006036023A1 (de) | 2008-02-07 |
| JP5149897B2 (ja) | 2013-02-20 |
| IL196789A0 (en) | 2009-11-18 |
| US20090192150A1 (en) | 2009-07-30 |
| ATE450537T1 (de) | 2009-12-15 |
| ES2336044T3 (es) | 2010-04-07 |
| BRPI0714599A2 (pt) | 2013-04-09 |
| HK1135694A1 (en) | 2010-06-11 |
| EP2054412A2 (de) | 2009-05-06 |
| DK2054412T3 (da) | 2010-04-19 |
| NO20090741L (no) | 2009-02-16 |
| AR062158A1 (es) | 2008-10-22 |
| DOP2007000120A (es) | 2008-02-29 |
| TWI400240B (zh) | 2013-07-01 |
| CA2663332A1 (en) | 2008-02-07 |
| WO2008014888A2 (de) | 2008-02-07 |
| EP2054412B1 (de) | 2009-12-02 |
| PT2054412E (pt) | 2010-02-04 |
| CA2663332C (en) | 2015-06-02 |
| KR20090129981A (ko) | 2009-12-17 |
| AU2007280780A1 (en) | 2008-02-07 |
| MX2009000408A (es) | 2009-01-27 |
| TW200821308A (en) | 2008-05-16 |
| WO2008014888A3 (de) | 2008-06-12 |
| CN101495478B (zh) | 2013-03-27 |
| CL2007002240A1 (es) | 2008-02-08 |
| MY148611A (en) | 2013-05-15 |
| US7863269B2 (en) | 2011-01-04 |
| CN101495478A (zh) | 2009-07-29 |
| AU2007280780B2 (en) | 2012-03-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD | Application declared void or lapsed |