PE20070356A1 - Metodo para el diseno de oligonucleotidos para tecnicas de biologia molecular - Google Patents

Metodo para el diseno de oligonucleotidos para tecnicas de biologia molecular

Info

Publication number
PE20070356A1
PE20070356A1 PE2006000995A PE2006000995A PE20070356A1 PE 20070356 A1 PE20070356 A1 PE 20070356A1 PE 2006000995 A PE2006000995 A PE 2006000995A PE 2006000995 A PE2006000995 A PE 2006000995A PE 20070356 A1 PE20070356 A1 PE 20070356A1
Authority
PE
Peru
Prior art keywords
oligonucleotides
molecular biology
design
sequences
interest
Prior art date
Application number
PE2006000995A
Other languages
English (en)
Inventor
Sepulveda Alejandro Eduardo Maass
Duarte Andres Octavio Aravena
Aguilera Servet Martinez
Stolzenbach Katia Nicole Ehrenfeld
Valdecantos Pilar Angelica Parada
Canales Mauricio Alejandro Gonzalez
Original Assignee
Biosigma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biosigma Sa filed Critical Biosigma Sa
Publication of PE20070356A1 publication Critical patent/PE20070356A1/es

Links

Classifications

    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G16B25/20Polymerase chain reaction [PCR]; Primer or probe design; Probe optimisation

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biotechnology (AREA)
  • Evolutionary Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medical Informatics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Theoretical Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

SE REFIERE A UN METODO PARA DISENAR OLIGONUCLEOTIDOS QUE PUEDEN SER USADOS EN PROCEDIMIENTOS DE BIOLOGIA MOLECULAR Y COMPRENDE: A) ELECCION O CONSTRUCCION DE UNA BASE DE DE DATOS PUBLICA DE GENES 16S; B) SELECCION DE SUBCONJUNTO DE SECUENCIAS CORRESPONDIENTES A LOS ORGANISMOS DE INTERES, SEGUN UNA CLASIFICACION TAXONOMICA; C) SELECCION A PARTIR DE SECUENCIAS DE OLIGONUCLEOTIDOS CANDIDATOS CONSIDERANDO TODAS LAS SUBSECUENCIAS DE UN LARGO DEFINIDO EXISTENTES EN LAS SECUENCIAS DE INTERES Y LAS SUBSECUENCIAS REVERSAS-COMPLEMENTARIAS DE ESTAS; D) DEPURACION DE ESTOS OLIGONUCLEOTIDOS CANDIDATOS DE ACUERDO A CRITERIOS DE ESPECIFICIDAD EN LA HIBIRIDACION Y ESTABILIDAD TERMODINAMICA; E) OBTENCION DE UNA LISTA DE OLIGONUCLEOTIDOS QUE CUMPLEN CON TODOS LOS REQUISITOS QUE CONSTITUYEN LOS OLIGONUCLEOTIDOS DISENADOS POR EL METODO. DICHO METODO PERMITE DETECTAR LA PRESENCIA DE LOS MICROORGANISMOS DEL TAXON SELECCIONADO EN UNA MUESTRA METAGENOMICA
PE2006000995A 2005-08-17 2006-08-16 Metodo para el diseno de oligonucleotidos para tecnicas de biologia molecular PE20070356A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CL2005002102 2005-08-17

Publications (1)

Publication Number Publication Date
PE20070356A1 true PE20070356A1 (es) 2007-04-05

Family

ID=40636643

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2006000995A PE20070356A1 (es) 2005-08-17 2006-08-16 Metodo para el diseno de oligonucleotidos para tecnicas de biologia molecular

Country Status (8)

Country Link
US (1) US7853408B2 (es)
AR (1) AR054923A1 (es)
AU (1) AU2006203551B2 (es)
BR (1) BRPI0604215A (es)
FR (1) FR2889845A1 (es)
MX (1) MXPA06009317A (es)
PE (1) PE20070356A1 (es)
ZA (1) ZA200606828B (es)

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WO2008119084A1 (en) * 2007-03-28 2008-10-02 The Children's Mercy Hospital Method for identifying and selecting low copy nucleic acid segments
WO2010072740A2 (en) 2008-12-23 2010-07-01 Astrazeneca Ab TARGETED BINDING AGENTS DIRECTED TO α5β1 AND USES THEREOF
PT2363502T (pt) * 2010-03-04 2017-05-17 Miacom Diagnostics Gmbh Fish multiplex melhorado
USRE49975E1 (en) * 2011-03-10 2024-05-21 Gen-Probe Incorporated Methods and compositions for the selection and optimization of oligonucleotide tag sequences
TWI772258B (zh) 2015-04-17 2022-08-01 德商安美基研究(慕尼黑)公司 Cdh3與cd3之雙特異性抗體構築體
TWI796283B (zh) 2015-07-31 2023-03-21 德商安美基研究(慕尼黑)公司 Msln及cd3抗體構築體
TWI793062B (zh) 2015-07-31 2023-02-21 德商安美基研究(慕尼黑)公司 Dll3及cd3抗體構築體
TWI744242B (zh) 2015-07-31 2021-11-01 德商安美基研究(慕尼黑)公司 Egfrviii及cd3抗體構築體
TWI829617B (zh) 2015-07-31 2024-01-21 德商安美基研究(慕尼黑)公司 Flt3及cd3抗體構築體
DK3411404T3 (da) 2016-02-03 2023-01-30 Amgen Res Munich Gmbh Psma- og cd3-bispecifikke t-celleinddragende antistofkonstruktioner
CR20180420A (es) 2016-02-03 2018-12-05 Amgen Inc Constructos de anticuerpo biespecíficos para bcma y cd3 que se ligan a células t
US20220148678A1 (en) * 2019-02-28 2022-05-12 Seegene, Inc. Methods for determining a designable region of oligonucleotides
EP4153633A1 (en) 2020-05-19 2023-03-29 Amgen Inc. Mageb2 binding constructs
WO2022074206A1 (en) 2020-10-08 2022-04-14 Affimed Gmbh Trispecific binders
AR124017A1 (es) 2020-11-06 2023-02-01 Amgen Res Munich Gmbh Polipéptidos con perfil de recorte potenciado
TW202233680A (zh) 2020-11-06 2022-09-01 德商安美基研究(慕尼黑)公司 具有增加的選擇性之多靶向性雙特異性抗原結合分子
KR20230104229A (ko) 2020-11-06 2023-07-07 암젠 인크 Cd3에 결합하는 폴리펩티드 구축물
TW202233679A (zh) 2020-11-06 2022-09-01 德商安美基研究(慕尼黑)公司 選擇性地與cldn6和cd3結合的多肽構建體
AU2022246675A1 (en) 2021-04-02 2023-10-19 Amgen Inc. Mageb2 binding constructs
JP2024518369A (ja) 2021-05-06 2024-05-01 アムジェン リサーチ (ミュニック) ゲゼルシャフト ミット ベシュレンクテル ハフツング 増殖性疾患で使用されるcd20及びcd22標的化抗原結合分子
WO2023007023A1 (en) 2021-07-30 2023-02-02 Affimed Gmbh Duplexbodies
CA3237018A1 (en) 2021-11-03 2023-05-11 Joachim Koch Bispecific cd16a binders
AR127568A1 (es) 2021-11-03 2024-02-07 Affimed Gmbh Ligandos biespecíficos de cd16a
WO2023218027A1 (en) 2022-05-12 2023-11-16 Amgen Research (Munich) Gmbh Multichain multitargeting bispecific antigen-binding molecules of increased selectivity
US20240036035A1 (en) * 2022-07-15 2024-02-01 The Regents Of The University Of Michigan Analyte detection using fluorogenic probes or multiplex technologies
WO2024059675A2 (en) 2022-09-14 2024-03-21 Amgen Inc. Bispecific molecule stabilizing composition

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030097223A1 (en) 1999-12-14 2003-05-22 Hitachi, Ltd. Primer design system

Also Published As

Publication number Publication date
FR2889845A1 (fr) 2007-02-23
BRPI0604215A (pt) 2007-04-10
AR054923A1 (es) 2007-07-25
MXPA06009317A (es) 2008-10-10
ZA200606828B (en) 2008-03-26
AU2006203551B2 (en) 2011-06-02
AU2006203551A1 (en) 2007-03-08
US20070059743A1 (en) 2007-03-15
US7853408B2 (en) 2010-12-14

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