PE20061074A1 - Derivados de piperidinil piperidina como inhibidores de receptores de quimioquinas - Google Patents

Derivados de piperidinil piperidina como inhibidores de receptores de quimioquinas

Info

Publication number
PE20061074A1
PE20061074A1 PE2006000213A PE2006000213A PE20061074A1 PE 20061074 A1 PE20061074 A1 PE 20061074A1 PE 2006000213 A PE2006000213 A PE 2006000213A PE 2006000213 A PE2006000213 A PE 2006000213A PE 20061074 A1 PE20061074 A1 PE 20061074A1
Authority
PE
Peru
Prior art keywords
alkyl
inhibitors
chemokine receptors
piperidine derivatives
piperidinyl piperidine
Prior art date
Application number
PE2006000213A
Other languages
English (en)
Inventor
Tze-Ming Chan
Kathleen Cox
Wenqing Feng
Daniel Weston
Stuart W Mccombie
Michael W Miller
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36570487&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20061074(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Schering Corp filed Critical Schering Corp
Publication of PE20061074A1 publication Critical patent/PE20061074A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • AIDS & HIV (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

REFERIDA A UN COMPUESTO DERIVADO DE PIPERIDINIL PIPERIDINA DE FORMULAS IA O IB, DONDE Y ES R-X- Y -N(R20)(R21); X ES C(R13)2, C(O), ENTRE OTROS; R ES R6-FENILO, R6-PIRIDILO, R6-NAFTILO, ENTRE OTROS; R1 ES H, ALQUILO Y ALQUENILO; R2 ES UN GRUPO PIRAZOL SUSTITUIDO; R3 ES R6-FENILO, R6-HETEROARILO, R6-NAFTILO; R7 Y R8 SON H, ALQUILO, HALOALQUILO, ENTRE OTROS; R14, R15 Y R16 SON H O ALQUILO; R34 ES R35O-, NH2, NHR35, R35R36N-; R35 ES ALQUILO, HALOALQUILO, ARALQUILO, ENTRE OTROS; R36 ES H, ALQUILO, FLUORALQUILO, ENTRE OTROS. TAMBIEN ESTA REFERIDA A UN PROCEDIMIENTO DE PREPARACION Y A UNA COMPOSICION FARMACEUTICA. DICHOS COMPUESTOS SON INHIBIDORES DE LOS RECEPTORES DE QUIMIOQUINAS, PARTICULARMENTE DE LOS RECEPTORES CCR5 Y SON UTILES PARA EL TRATAMIENTO DEL VIH, ARTRITIS, ARTRITIS REUMATOIDEA, ENTRE OTROS
PE2006000213A 2005-02-23 2006-02-21 Derivados de piperidinil piperidina como inhibidores de receptores de quimioquinas PE20061074A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US65553805P 2005-02-23 2005-02-23

Publications (1)

Publication Number Publication Date
PE20061074A1 true PE20061074A1 (es) 2006-11-08

Family

ID=36570487

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2006000213A PE20061074A1 (es) 2005-02-23 2006-02-21 Derivados de piperidinil piperidina como inhibidores de receptores de quimioquinas

Country Status (10)

Country Link
US (1) US7705019B2 (es)
EP (1) EP1858886A1 (es)
JP (1) JP4822367B2 (es)
CN (1) CN101133050A (es)
AR (1) AR055313A1 (es)
CA (1) CA2598568A1 (es)
MX (1) MX2007010257A (es)
PE (1) PE20061074A1 (es)
TW (1) TW200640909A (es)
WO (1) WO2006091534A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2562235C (en) 2004-04-13 2013-09-24 Incyte Corporation Piperazinylpiperidine derivatives as chemokine receptor antagonists

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6387930B1 (en) * 1999-05-04 2002-05-14 Schering Corporation Piperidine derivatives useful as CCR5 antagonists
IL145742A0 (en) 1999-05-04 2002-07-25 Schering Corp Piperidine derivatives useful as ccr5 antagonists
AR033517A1 (es) * 2000-04-08 2003-12-26 Astrazeneca Ab Derivados de piperidina, proceso para su preparacion y uso de estos derivados en la fabricacion de medicamentos
AU2002255947B8 (en) * 2001-03-29 2005-11-17 Schering Corporation CCR5 antagonists useful for treating AIDS
AR036366A1 (es) * 2001-08-29 2004-09-01 Schering Corp Derivados de piperidina utiles como antagonistas de ccr5, composiciones farmaceuticas, el uso de dichos derivados para la fabricación de un medicamento y un kit
GB0223223D0 (en) * 2002-10-07 2002-11-13 Novartis Ag Organic compounds
PE20040769A1 (es) * 2002-12-18 2004-11-06 Schering Corp Derivados de piperidina utiles como antagonisas ccr5

Also Published As

Publication number Publication date
MX2007010257A (es) 2007-09-11
JP2008531566A (ja) 2008-08-14
JP4822367B2 (ja) 2011-11-24
CN101133050A (zh) 2008-02-27
US20060223856A1 (en) 2006-10-05
US7705019B2 (en) 2010-04-27
AR055313A1 (es) 2007-08-15
CA2598568A1 (en) 2006-08-31
EP1858886A1 (en) 2007-11-28
TW200640909A (en) 2006-12-01
WO2006091534A1 (en) 2006-08-31

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