PE20060678A1 - Formas cristalinas de derivados de etilamina y procedimiento de preparacion de los mismos - Google Patents
Formas cristalinas de derivados de etilamina y procedimiento de preparacion de los mismosInfo
- Publication number
- PE20060678A1 PE20060678A1 PE2005000372A PE2005000372A PE20060678A1 PE 20060678 A1 PE20060678 A1 PE 20060678A1 PE 2005000372 A PE2005000372 A PE 2005000372A PE 2005000372 A PE2005000372 A PE 2005000372A PE 20060678 A1 PE20060678 A1 PE 20060678A1
- Authority
- PE
- Peru
- Prior art keywords
- compound
- procedure
- preparation
- monoclorhydrate
- polymorph
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- QUSNBJAOOMFDIB-UHFFFAOYSA-N Ethylamine Chemical class CCN QUSNBJAOOMFDIB-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- 230000000694 effects Effects 0.000 abstract 2
- 230000001681 protective effect Effects 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 229940121786 Beta 2 adrenoreceptor agonist Drugs 0.000 abstract 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical group [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 abstract 1
- -1 HYDROXYL GROUP Chemical group 0.000 abstract 1
- 208000018569 Respiratory Tract disease Diseases 0.000 abstract 1
- 206010057190 Respiratory tract infections Diseases 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 238000005349 anion exchange Methods 0.000 abstract 1
- 229940125890 compound Ia Drugs 0.000 abstract 1
- 238000010511 deprotection reaction Methods 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000005588 protonation Effects 0.000 abstract 1
- 230000002685 pulmonary effect Effects 0.000 abstract 1
- 208000020029 respiratory tract infectious disease Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/34—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
- C07C233/42—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
- C07C233/43—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of a saturated carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0407521A GB0407521D0 (en) | 2004-04-02 | 2004-04-02 | Chemical process |
| GB0411688A GB0411688D0 (en) | 2004-05-25 | 2004-05-25 | Chemical process |
| US57446704P | 2004-05-26 | 2004-05-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20060678A1 true PE20060678A1 (es) | 2006-08-02 |
Family
ID=34963396
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2005000372A PE20060678A1 (es) | 2004-04-02 | 2005-03-31 | Formas cristalinas de derivados de etilamina y procedimiento de preparacion de los mismos |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US7846973B2 (https=) |
| EP (1) | EP1730104A1 (https=) |
| JP (1) | JP2007530652A (https=) |
| AR (1) | AR052301A1 (https=) |
| AU (1) | AU2005227733A1 (https=) |
| BR (1) | BRPI0509382A (https=) |
| CA (1) | CA2561400A1 (https=) |
| IL (1) | IL178064A0 (https=) |
| MA (1) | MA28558B1 (https=) |
| NO (1) | NO20064884L (https=) |
| PE (1) | PE20060678A1 (https=) |
| TW (1) | TW200536814A (https=) |
| WO (1) | WO2005095328A1 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006066907A1 (en) * | 2004-12-21 | 2006-06-29 | Glaxo Group Limited | Pharmaceutical formulations |
| GB0601951D0 (en) | 2006-01-31 | 2006-03-15 | Novartis Ag | Organic compounds |
| MX2010007604A (es) | 2008-01-11 | 2010-08-02 | Novartis Ag | Pirimidinas como inhibidores de cinasa. |
| WO2011061527A1 (en) | 2009-11-17 | 2011-05-26 | Astrazeneca Ab | Combinations comprising a glucocorticoid receptor modulator for the treatment of respiratory diseases |
| IT1399912B1 (it) * | 2010-04-29 | 2013-05-09 | Lundbeck Pharmaceuticals Italy S Pa | Processo di preparazione di ritodrina cloridrato. |
| JP5645762B2 (ja) * | 2010-06-29 | 2014-12-24 | 日本ポリプロ株式会社 | ポリオレフィンの結晶性分布分析方法およびその装置 |
| WO2012034095A1 (en) | 2010-09-09 | 2012-03-15 | Irm Llc | Compounds and compositions as trk inhibitors |
| US8637516B2 (en) | 2010-09-09 | 2014-01-28 | Irm Llc | Compounds and compositions as TRK inhibitors |
| WO2012116217A1 (en) | 2011-02-25 | 2012-08-30 | Irm Llc | Compounds and compositions as trk inhibitors |
| GB201212081D0 (en) * | 2012-07-06 | 2012-08-22 | Kalvista Pharmaceuticals Ltd | New polymorph |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2064336B (en) | 1979-12-06 | 1984-03-14 | Glaxo Group Ltd | Device for dispensing medicaments |
| US4353656A (en) | 1980-10-14 | 1982-10-12 | Xerox Corporation | Moving coil, multiple energy print hammer system including a closed loop servo |
| DE3274065D1 (de) | 1981-07-08 | 1986-12-11 | Draco Ab | Powder inhalator |
| GB2169265B (en) | 1982-10-08 | 1987-08-12 | Glaxo Group Ltd | Pack for medicament |
| US4778054A (en) | 1982-10-08 | 1988-10-18 | Glaxo Group Limited | Pack for administering medicaments to patients |
| DK172541B1 (da) | 1982-10-08 | 1998-12-07 | Glaxo Group Ltd | Apparat til administrering af medikamenter til patienter og en medikamentpakning til brug i apparatet |
| DE3682457D1 (de) | 1985-07-30 | 1991-12-19 | Glaxo Group Ltd | Geraet zur verabreichung von medikamenten an patienten. |
| GB9004781D0 (en) | 1990-03-02 | 1990-04-25 | Glaxo Group Ltd | Device |
| HU225869B1 (en) | 1992-04-02 | 2007-11-28 | Smithkline Beecham Corp | Compounds with antiallergic and antiinflammatory activity and pharmaceutical compns. contg. them |
| US5495054A (en) | 1994-05-31 | 1996-02-27 | Sepracor, Inc. | Tetrahydroindeno[1,2-D][1,3,2]oxazaboroles and their use as enantioselective catalysts |
| US6040344A (en) | 1996-11-11 | 2000-03-21 | Sepracor Inc. | Formoterol process |
| GB9700226D0 (en) | 1997-01-08 | 1997-02-26 | Glaxo Group Ltd | Inhalation device |
| UA73965C2 (en) | 1999-12-08 | 2005-10-17 | Theravance Inc | b2 ADRENERGIC RECEPTOR ANTAGONISTS |
| OA11558A (en) | 1999-12-08 | 2004-06-03 | Advanced Medicine Inc | Beta 2-adrenergic receptor agonists. |
| US6632666B2 (en) | 2000-01-14 | 2003-10-14 | Biolife Solutions, Inc. | Normothermic, hypothermic and cryopreservation maintenance and storage of cells, tissues and organs in gel-based media |
| TWI249515B (en) * | 2001-11-13 | 2006-02-21 | Theravance Inc | Aryl aniline beta2 adrenergic receptor agonists |
| GB0201677D0 (en) | 2002-01-25 | 2002-03-13 | Glaxo Group Ltd | Medicament dispenser |
| AR040661A1 (es) * | 2002-07-26 | 2005-04-13 | Theravance Inc | Diclorhidrato cristalino de n-{2-[-((r)-2-hidroxi-2-feniletilamino)fenil]etil}-(r)-2hidroxi-2-(3-formamido-4-hidroxifenil)etilamina, agonista del receptor adrenergico beta 2 |
| CN100387598C (zh) | 2002-09-16 | 2008-05-14 | 葛兰素集团有限公司 | 吡唑并[3,4-b]吡啶化合物及其作为磷酸二酯酶抑制剂的用途 |
| TW200510277A (en) | 2003-05-27 | 2005-03-16 | Theravance Inc | Crystalline form of β2-adrenergic receptor agonist |
-
2005
- 2005-03-30 WO PCT/GB2005/001241 patent/WO2005095328A1/en not_active Ceased
- 2005-03-30 JP JP2007505632A patent/JP2007530652A/ja active Pending
- 2005-03-30 US US10/599,145 patent/US7846973B2/en not_active Expired - Fee Related
- 2005-03-30 CA CA002561400A patent/CA2561400A1/en not_active Abandoned
- 2005-03-30 AU AU2005227733A patent/AU2005227733A1/en not_active Abandoned
- 2005-03-30 BR BRPI0509382-1A patent/BRPI0509382A/pt not_active IP Right Cessation
- 2005-03-30 EP EP05729685A patent/EP1730104A1/en not_active Withdrawn
- 2005-03-31 PE PE2005000372A patent/PE20060678A1/es not_active Application Discontinuation
- 2005-03-31 TW TW094110351A patent/TW200536814A/zh unknown
- 2005-03-31 AR ARP050101278A patent/AR052301A1/es not_active Application Discontinuation
-
2006
- 2006-09-13 IL IL178064A patent/IL178064A0/en unknown
- 2006-10-26 NO NO20064884A patent/NO20064884L/no not_active Application Discontinuation
- 2006-10-30 MA MA29421A patent/MA28558B1/fr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| TW200536814A (en) | 2005-11-16 |
| CA2561400A1 (en) | 2005-10-13 |
| WO2005095328A1 (en) | 2005-10-13 |
| KR20070000508A (ko) | 2007-01-02 |
| JP2007530652A (ja) | 2007-11-01 |
| US7846973B2 (en) | 2010-12-07 |
| MA28558B1 (fr) | 2007-04-03 |
| NO20064884L (no) | 2006-10-26 |
| BRPI0509382A (pt) | 2007-09-18 |
| EP1730104A1 (en) | 2006-12-13 |
| IL178064A0 (en) | 2006-12-31 |
| US20100063157A1 (en) | 2010-03-11 |
| AR052301A1 (es) | 2007-03-14 |
| AU2005227733A1 (en) | 2005-10-13 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX375261B (es) | Compuestos aromaticos sustituidos para el tratamiento de la fibrosis pulmonar, la fibrosis hepatica, la fibrosis de la piel y la fibrosis cardiaca. | |
| WO2008062905A3 (en) | Heteromonocyclic compound and use thereof | |
| BRPI0201437B8 (pt) | processos para a preparação de derivados de 9-desoxo-9a-aza-9a-homoeritromicina a 4"-substituídos | |
| CO6220955A2 (es) | Una composicion farmaceutica que contiene (a) n1-(5-cloropiridin-2-il)-n2-((1s,2r,4s)-4-[dimetilamino)carbonil]-2-{[(5-metil-4,5,6,7-tetrahidrotiazol[5,4-c]piridin-2-il) carbonil] amino} coclohexil)etanodiamida | |
| BR112014003476A2 (pt) | compostos contendo nitrogênio e seu uso | |
| WO2008131149A3 (en) | Crystal forms of saxagliptin and processes for preparing same | |
| NZ597645A (en) | Compositions containing berberine or analogs thereof for treating rosacea or red face related skin disorders | |
| BR112015006341A2 (pt) | compostos, composição farmacêutica, método para tratar condição fibrótica, quantidade terapeuticamente efetiva de composto, de sal farmaceuticamente aceitável deste ou de composição farmacêutica e usos das mesmas e de compostos e/ou composição farmacêutica | |
| PE20060678A1 (es) | Formas cristalinas de derivados de etilamina y procedimiento de preparacion de los mismos | |
| EP2639229A3 (en) | Thiazole Derivative and use thereof as VAP-1 Inhibitor | |
| BRPI0409211A (pt) | composto, composição farmacêutica, métodos para ativar receptores 5-ht1f, para inibir extravasão de proteìna neuronial, e para o tratamento ou prevenção de enxaqueca em um mamìfero, e, uso de um composto | |
| MX2011009709A (es) | Compuestos para el tratamiento de la inflamacion y del dolor. | |
| PH12014500065A1 (en) | A new therapeutical composition containing apomorphine as active ingredient | |
| MX2023003332A (es) | Inhibidores del elemento 1 interdispersado largo (line-1) para el tratamiento de enfermedades. | |
| PE20040767A1 (es) | Derivado hemisulfato de azido citosina cristalino anhidro | |
| CL2011001829A1 (es) | 3'-n-desmetil-4''-o-(2-dietilaminoetanoil)-6-o-metil-9a-aza-9a-homoeritromicina a, sus sales y formas cristalinas 1, 2 y 3; proceso de preparacion; uso para tratar enfermedades inflamatorias; composicion farmaceutica; y composicion que ademas comprende otro compuesto activo. | |
| TN2014000031A1 (en) | Use of organic compound for the treatment of noonan syndrome | |
| BRPI0508392A (pt) | materiais e métodos para tratar distúrbios de coagulação | |
| BRPI0712312A2 (pt) | Composto, processo para a produção do mesmo, composição farmacêutica, agente antimicrobiano, agente anti-mrsa, método para a prevenção ou o tratamento de uma doença infecciosa, e, uso do composto | |
| WO2006051314A8 (en) | Guanidine derivatives as inhibitors of ddah | |
| WO2011037833A3 (en) | Novel n-benzylamide substituted derivatives of 2-(acylamido)acetic acid and 2-(acylamido)propionic acids: potent neurological agents | |
| WO2010019203A8 (en) | Antifungal agents | |
| MX2009011818A (es) | Formulaciones de aminoacido n-halogenado con compuestos anti-inflamatorios. | |
| ECSP21093897A (es) | Compuestos y métodos de uso de los mismos como agentes antibacterianos | |
| PH12022552763A1 (en) | Medical use of daridorexant |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC | Refusal |