PE20040350A1 - Compuestos heterociclicos no esteroideos como moduladores del receptor de la progesterona - Google Patents

Compuestos heterociclicos no esteroideos como moduladores del receptor de la progesterona

Info

Publication number
PE20040350A1
PE20040350A1 PE2003000343A PE2003000343A PE20040350A1 PE 20040350 A1 PE20040350 A1 PE 20040350A1 PE 2003000343 A PE2003000343 A PE 2003000343A PE 2003000343 A PE2003000343 A PE 2003000343A PE 20040350 A1 PE20040350 A1 PE 20040350A1
Authority
PE
Peru
Prior art keywords
alkyl
alkenyl
progesterone receptor
pyrid
dibenzo
Prior art date
Application number
PE2003000343A
Other languages
English (en)
Spanish (es)
Inventor
Paul Peter Marie Antonius Dols
Brigitte Johanna Bernita Folmer
Hans Lucas
Johannes Bernardus Maria Rewinkel
Pedro Harold Han Hermkens
Original Assignee
Akzo Nobel Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv
Publication of PE20040350A1 publication Critical patent/PE20040350A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/36—Antigestagens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Gynecology & Obstetrics (AREA)
  • Hematology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PE2003000343A 2002-04-04 2003-04-03 Compuestos heterociclicos no esteroideos como moduladores del receptor de la progesterona PE20040350A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP02076350 2002-04-04

Publications (1)

Publication Number Publication Date
PE20040350A1 true PE20040350A1 (es) 2004-06-17

Family

ID=28685924

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2003000343A PE20040350A1 (es) 2002-04-04 2003-04-03 Compuestos heterociclicos no esteroideos como moduladores del receptor de la progesterona

Country Status (30)

Country Link
US (1) US7737136B2 (pt)
EP (1) EP1495030B1 (pt)
JP (1) JP4418683B2 (pt)
KR (1) KR100965173B1 (pt)
CN (1) CN1279044C (pt)
AR (1) AR039251A1 (pt)
AT (1) ATE404567T1 (pt)
AU (1) AU2003224161B2 (pt)
BR (1) BR0308890A (pt)
CA (1) CA2480940C (pt)
CY (1) CY1108495T1 (pt)
DE (1) DE60322867D1 (pt)
DK (1) DK1495030T3 (pt)
EC (1) ECSP045334A (pt)
ES (1) ES2310654T3 (pt)
HK (1) HK1070362A1 (pt)
HR (1) HRP20040913A2 (pt)
IL (2) IL164169A0 (pt)
IS (1) IS7452A (pt)
MX (1) MXPA04009709A (pt)
NO (1) NO20044473L (pt)
NZ (1) NZ535546A (pt)
PE (1) PE20040350A1 (pt)
PL (1) PL372846A1 (pt)
PT (1) PT1495030E (pt)
RU (1) RU2309155C2 (pt)
SI (1) SI1495030T1 (pt)
TW (1) TWI297685B (pt)
WO (1) WO2003084963A1 (pt)
ZA (1) ZA200407667B (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI297685B (en) 2002-04-04 2008-06-11 Organon Nv Non-steroidal progesterone receptor modulators
TWI370129B (en) * 2005-02-14 2012-08-11 Msd Oss Bv Non steroidal glucocorticoid receptor modulators
TWI375676B (en) * 2005-08-29 2012-11-01 Msd Oss Bv Non-steroidal glucocorticoid receptor modulators
ATE478078T1 (de) * 2006-09-27 2010-09-15 Organon Nv Pyridooxazepin-progesteronrezeptor-modulatoren
US7989442B2 (en) 2006-09-27 2011-08-02 N.V. Organon Progesterone receptor modulators
US8063037B2 (en) * 2007-05-07 2011-11-22 N. V. Organon Progesterone receptor modulators
TW200914029A (en) * 2007-05-07 2009-04-01 Organon Nv New progesterone receptor modulators

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4054572A (en) * 1973-04-26 1977-10-18 Akzona Incorporated Hexahydro pyridine [1,2d] dibenza [b,f] (1,4)-diazepines
NL7305811A (pt) * 1973-04-26 1974-10-29
US4016161A (en) * 1974-04-24 1977-04-05 Akzona Incorporated Amino-substituted 1,2,3,4,10,146-hexahydro-pyridino[1,2-a]dibenzo[c,f]azepines
ATE86484T1 (de) 1987-08-08 1993-03-15 Akzo Nv Kontrazeptives implantat.
CA2026856A1 (en) * 1989-10-05 1991-04-06 Mark G. Bock 3-substituted-1,4-benzodiazepines useful as oxytocin
US5688810A (en) * 1994-12-22 1997-11-18 Ligand Pharmaceuticals Incorporated Steroid receptor modulator compounds and methods
TW358031B (en) 1997-04-11 1999-05-11 Akze Nobel N V Drug delivery system for 2 or more active substances
TWI297685B (en) 2002-04-04 2008-06-11 Organon Nv Non-steroidal progesterone receptor modulators
TWI370129B (en) 2005-02-14 2012-08-11 Msd Oss Bv Non steroidal glucocorticoid receptor modulators
ATE478078T1 (de) 2006-09-27 2010-09-15 Organon Nv Pyridooxazepin-progesteronrezeptor-modulatoren

Also Published As

Publication number Publication date
PL372846A1 (en) 2005-08-08
RU2004132215A (ru) 2005-04-20
HRP20040913A2 (en) 2005-08-31
KR100965173B1 (ko) 2010-06-24
MXPA04009709A (es) 2004-12-13
JP4418683B2 (ja) 2010-02-17
TWI297685B (en) 2008-06-11
DE60322867D1 (de) 2008-09-25
CY1108495T1 (el) 2014-04-09
NO20044473L (no) 2004-10-29
EP1495030A1 (en) 2005-01-12
NZ535546A (en) 2007-01-26
JP2005528382A (ja) 2005-09-22
AU2003224161A1 (en) 2003-10-20
TW200307675A (en) 2003-12-16
WO2003084963A1 (en) 2003-10-16
HK1070362A1 (en) 2005-06-17
CA2480940C (en) 2011-02-08
BR0308890A (pt) 2005-01-11
ZA200407667B (en) 2006-07-26
IL164169A0 (en) 2005-12-18
US20050171087A1 (en) 2005-08-04
DK1495030T3 (da) 2008-11-24
SI1495030T1 (sl) 2009-02-28
RU2309155C2 (ru) 2007-10-27
CN1649879A (zh) 2005-08-03
CN1279044C (zh) 2006-10-11
PT1495030E (pt) 2008-11-21
IL164169A (en) 2010-11-30
CA2480940A1 (en) 2003-10-16
IS7452A (is) 2004-09-16
AR039251A1 (es) 2005-02-16
EP1495030B1 (en) 2008-08-13
ES2310654T3 (es) 2009-01-16
KR20040099396A (ko) 2004-11-26
AU2003224161B2 (en) 2009-02-26
US7737136B2 (en) 2010-06-15
ATE404567T1 (de) 2008-08-15
ECSP045334A (es) 2004-11-26

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