NO20044473L - Ikke-steroidal progesteron reseptor modulatorer - Google Patents

Ikke-steroidal progesteron reseptor modulatorer

Info

Publication number
NO20044473L
NO20044473L NO20044473A NO20044473A NO20044473L NO 20044473 L NO20044473 L NO 20044473L NO 20044473 A NO20044473 A NO 20044473A NO 20044473 A NO20044473 A NO 20044473A NO 20044473 L NO20044473 L NO 20044473L
Authority
NO
Norway
Prior art keywords
progesterone receptor
receptor modulators
steroidal progesterone
steroidal
prodrug
Prior art date
Application number
NO20044473A
Other languages
English (en)
Inventor
Johannes Bernardus Ma Rewinkel
Paul Peter Marie Antonius Dols
Pedro Harold Han Hermkens
Hans Lucas
Birgitte Johanna Bernit Folmer
Original Assignee
Akzo Nobel Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv
Publication of NO20044473L publication Critical patent/NO20044473L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/36—Antigestagens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Gynecology & Obstetrics (AREA)
  • Hematology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Foreliggende oppfinnelse tilveiebringer forbindelser med den generelle Formel I, et prodrug derav, et farmasøytisk akseptabelt salt derav eller et farmasøytisk akseptabelt salt av et prodrug derav. Mer spesielt tilveiebringer foreliggende oppfinnelse høyaffinitet ikke-steroide forbindelser som er agonister, partielle agonister eller antagonister for progesteron-reseptoren.
NO20044473A 2002-04-04 2004-10-20 Ikke-steroidal progesteron reseptor modulatorer NO20044473L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP02076350 2002-04-04
PCT/EP2003/050085 WO2003084963A1 (en) 2002-04-04 2003-04-01 Non-steroidal progesterone receptor modulators

Publications (1)

Publication Number Publication Date
NO20044473L true NO20044473L (no) 2004-10-29

Family

ID=28685924

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20044473A NO20044473L (no) 2002-04-04 2004-10-20 Ikke-steroidal progesteron reseptor modulatorer

Country Status (30)

Country Link
US (1) US7737136B2 (no)
EP (1) EP1495030B1 (no)
JP (1) JP4418683B2 (no)
KR (1) KR100965173B1 (no)
CN (1) CN1279044C (no)
AR (1) AR039251A1 (no)
AT (1) ATE404567T1 (no)
AU (1) AU2003224161B2 (no)
BR (1) BR0308890A (no)
CA (1) CA2480940C (no)
CY (1) CY1108495T1 (no)
DE (1) DE60322867D1 (no)
DK (1) DK1495030T3 (no)
EC (1) ECSP045334A (no)
ES (1) ES2310654T3 (no)
HK (1) HK1070362A1 (no)
HR (1) HRP20040913A2 (no)
IL (2) IL164169A0 (no)
IS (1) IS7452A (no)
MX (1) MXPA04009709A (no)
NO (1) NO20044473L (no)
NZ (1) NZ535546A (no)
PE (1) PE20040350A1 (no)
PL (1) PL372846A1 (no)
PT (1) PT1495030E (no)
RU (1) RU2309155C2 (no)
SI (1) SI1495030T1 (no)
TW (1) TWI297685B (no)
WO (1) WO2003084963A1 (no)
ZA (1) ZA200407667B (no)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI297685B (en) 2002-04-04 2008-06-11 Organon Nv Non-steroidal progesterone receptor modulators
TWI370129B (en) * 2005-02-14 2012-08-11 Msd Oss Bv Non steroidal glucocorticoid receptor modulators
TWI375676B (en) * 2005-08-29 2012-11-01 Msd Oss Bv Non-steroidal glucocorticoid receptor modulators
NZ575276A (en) * 2006-09-27 2011-07-29 Organon Nv Pyridooxazepine progesterone receptor modulators
US7989442B2 (en) 2006-09-27 2011-08-02 N.V. Organon Progesterone receptor modulators
US8063037B2 (en) * 2007-05-07 2011-11-22 N. V. Organon Progesterone receptor modulators
TW200914029A (en) * 2007-05-07 2009-04-01 Organon Nv New progesterone receptor modulators

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7305811A (no) 1973-04-26 1974-10-29
US4054572A (en) * 1973-04-26 1977-10-18 Akzona Incorporated Hexahydro pyridine [1,2d] dibenza [b,f] (1,4)-diazepines
US4016161A (en) * 1974-04-24 1977-04-05 Akzona Incorporated Amino-substituted 1,2,3,4,10,146-hexahydro-pyridino[1,2-a]dibenzo[c,f]azepines
ATE86484T1 (de) 1987-08-08 1993-03-15 Akzo Nv Kontrazeptives implantat.
CA2026856A1 (en) 1989-10-05 1991-04-06 Mark G. Bock 3-substituted-1,4-benzodiazepines useful as oxytocin
US5696127A (en) 1994-12-22 1997-12-09 Ligand Pharmaceuticals Incorporated Steroid receptor modulator compounds and methods
IL123813A0 (en) 1997-04-11 1998-10-30 Akzo Nobel Nv Drug delivery system for two or more active substances
TWI297685B (en) 2002-04-04 2008-06-11 Organon Nv Non-steroidal progesterone receptor modulators
TWI370129B (en) 2005-02-14 2012-08-11 Msd Oss Bv Non steroidal glucocorticoid receptor modulators
NZ575276A (en) 2006-09-27 2011-07-29 Organon Nv Pyridooxazepine progesterone receptor modulators

Also Published As

Publication number Publication date
HRP20040913A2 (en) 2005-08-31
ZA200407667B (en) 2006-07-26
EP1495030A1 (en) 2005-01-12
NZ535546A (en) 2007-01-26
IL164169A0 (en) 2005-12-18
WO2003084963A1 (en) 2003-10-16
BR0308890A (pt) 2005-01-11
US20050171087A1 (en) 2005-08-04
EP1495030B1 (en) 2008-08-13
HK1070362A1 (en) 2005-06-17
IL164169A (en) 2010-11-30
TWI297685B (en) 2008-06-11
AU2003224161B2 (en) 2009-02-26
DK1495030T3 (da) 2008-11-24
PL372846A1 (en) 2005-08-08
CA2480940A1 (en) 2003-10-16
CA2480940C (en) 2011-02-08
KR20040099396A (ko) 2004-11-26
US7737136B2 (en) 2010-06-15
MXPA04009709A (es) 2004-12-13
TW200307675A (en) 2003-12-16
RU2309155C2 (ru) 2007-10-27
CN1649879A (zh) 2005-08-03
CN1279044C (zh) 2006-10-11
KR100965173B1 (ko) 2010-06-24
ES2310654T3 (es) 2009-01-16
JP4418683B2 (ja) 2010-02-17
SI1495030T1 (sl) 2009-02-28
AU2003224161A1 (en) 2003-10-20
JP2005528382A (ja) 2005-09-22
DE60322867D1 (de) 2008-09-25
CY1108495T1 (el) 2014-04-09
PT1495030E (pt) 2008-11-21
ECSP045334A (es) 2004-11-26
RU2004132215A (ru) 2005-04-20
PE20040350A1 (es) 2004-06-17
IS7452A (is) 2004-09-16
AR039251A1 (es) 2005-02-16
ATE404567T1 (de) 2008-08-15

Similar Documents

Publication Publication Date Title
NO20034289L (no) N-(2-aryletyl)benzylaminer som antagonister av 5-HT6- reseptoren
ATE496620T1 (de) 1h-benzo(f)indazol-5-yl-derivate als selektive glucocorticoid-rezeptor-modulatoren
NO20041504L (no) Lactamderivater som antagonister for humane 11CBY reseptorer.
NO20060195L (no) Kinolylamidderivater som CCR-5-antagonister
EA200700365A1 (ru) Производные индол-2-карбоксамидина как антагонисты nmda рецептора
IS6902A (is) N-setin heterósýklísk NMDA/NR2B mótlyf sem ekki eru arýl
DE602006017694D1 (de) C-verknüpfte zyklische antagonisten des p2y1-rezeptors mit eignung bei der behandlung thrombotischer leiden
CY1109543T1 (el) Βασικοι μη-πεπτιδικοι ανταγωνιστες βραδυκινινης και 5 φαρμακευτικες συνθεσεις απο αυτους
ATE399770T1 (de) Tachykininrezeptorantagonisten
NO20062021L (no) Omleirede pentanoler, fremgangsmpte for fremstilling av dette, og deres anvendelse som antiflogistika
NO20061981L (no) Arylindenopyridiner og arylindenopyridiner og deres anvendelse som adenosin A2A reseptoragonist
BR0206595A (pt) Composto, composição farmacêutica, e uso de um composto
ATE447575T1 (de) Selektive spirocyclische glucocorticoid-rezeptor- modulatoren
NO20044473L (no) Ikke-steroidal progesteron reseptor modulatorer
NO20014855D0 (no) N-(2-fenyl-4-aminobutyl)-1-naftamider som neurokinin-1- reseptorantagonister
EA200602081A1 (ru) Пиридиновые производные алкилоксиндолов в качестве агентов, активных в отношении рецептора 5-нт7
NO20030297L (no) Aryl sulfonamider som serotoninantagonist for behandling av fedme
ATE448220T1 (de) Heterocyclische modulatoren für den gaba-alpha- subtyp-selektiven rezeptor
SE0303418D0 (sv) New use 1
NO20080947L (no) Terapeutisk middel for hypertensjon
SE0303488D0 (sv) New use 1X
SE0303419D0 (sv) New use 11
SE0303489D0 (sv) New use VII

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application