PA8663601A1 - Derivados del 1,5-diarilpirol, su preparacion y su aplicacion en terapia - Google Patents
Derivados del 1,5-diarilpirol, su preparacion y su aplicacion en terapiaInfo
- Publication number
- PA8663601A1 PA8663601A1 PA20068663601A PA8663601A PA8663601A1 PA 8663601 A1 PA8663601 A1 PA 8663601A1 PA 20068663601 A PA20068663601 A PA 20068663601A PA 8663601 A PA8663601 A PA 8663601A PA 8663601 A1 PA8663601 A1 PA 8663601A1
- Authority
- PA
- Panama
- Prior art keywords
- replaced
- radical
- rent
- therapy
- preparation
- Prior art date
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/323—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to the ring nitrogen atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/325—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/402—1-aryl substituted, e.g. piretanide
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
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- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
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- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
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- Neurology (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Reproductive Health (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
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- Vascular Medicine (AREA)
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- Pregnancy & Childbirth (AREA)
- Heart & Thoracic Surgery (AREA)
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Abstract
LA PRESENTE INVENCION TIENE COMO OBJETIVO COMPUESTOS QUE RESPONDEN A LA FORMULA: EN LA QUE: -X REPRESENTA UN GRUPO -C-, -SO2-, -C-N(R7)-, -C-(R7)-; - R1 Y R6 REPRESENTAN UN ATOMO DE HIDROGENO O UN GRUPO ALQUILO; - R2 REPRESENTA UN RADICAL ELEGIDO ENTRE: .UN ALQUILO (C1-C12); .UN RADICAL CARBOCICLICO NO AROMATICO (3-C12); .UN CICLOALQUIL (C3-C7)-METILO; .UN FENILO, UN BENCILO, UN BENCIDRILO, UN BENCIDRILMETILO, UN FENETILO;.UN BENZODIOXOLILO, UN DIHIDROBENZOFURANILO, UN DIHIDROBENZODIOXINILO; .UN METILO SUSTITUIDO CON UN BENZODIOXOLILO, UN DEHIDROBENZOFURANILO O UN DIHIDROBENZODIOXINILO; .UN 1,2,3,4-TETRAHIDRONAFTALENILO NO SUSTITUIDO;O .UN RADICAL HETEROCICLICO, UN INDOLILO, UN BENZOTIAZOLILO NO SUSTITUIDO O SUSTITUIDO; ESTANDO DICHOS RADICALES NO SUSTITUIDOS O SUSTITUIDOS; -R3 REPRESENTA UN ALQUILO (C1-C5) O UN CICLOALQUILO (C3-C7); -R4YR5 REPRESENTAN UN FENILO NO SUSTITUIDO O SUSTITUIDO. PROCEDIMIENTO DE PREPARACION Y APLICACION EN TERAPIA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0501660A FR2882054B1 (fr) | 2005-02-17 | 2005-02-17 | Derives de 1,5-diarylpyrrole, leur preparation et leur application en therapeutique |
Publications (1)
Publication Number | Publication Date |
---|---|
PA8663601A1 true PA8663601A1 (es) | 2006-11-09 |
Family
ID=34954653
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PA20068663601A PA8663601A1 (es) | 2005-02-17 | 2006-02-17 | Derivados del 1,5-diarilpirol, su preparacion y su aplicacion en terapia |
Country Status (18)
Country | Link |
---|---|
US (1) | US7524971B2 (es) |
EP (1) | EP1853557A2 (es) |
JP (1) | JP2008530187A (es) |
KR (1) | KR20070103454A (es) |
CN (1) | CN101119967A (es) |
AR (1) | AR052673A1 (es) |
AU (1) | AU2006215521A1 (es) |
BR (1) | BRPI0608866A2 (es) |
CA (1) | CA2597033A1 (es) |
DO (1) | DOP2006000043A (es) |
FR (1) | FR2882054B1 (es) |
IL (1) | IL185034A0 (es) |
PA (1) | PA8663601A1 (es) |
RU (1) | RU2007134383A (es) |
SV (1) | SV2007002420A (es) |
TW (1) | TW200714585A (es) |
UY (1) | UY29373A1 (es) |
WO (1) | WO2006087476A2 (es) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2874012B1 (fr) * | 2004-08-09 | 2008-08-22 | Sanofi Synthelabo | Derives de pyrrole, leur preparation et leur utlisation en therapeutique |
FR2894579B1 (fr) * | 2005-12-12 | 2008-01-18 | Sanofi Aventis Sa | Derives diaryltriazolmethylamine, leur preparation et leur application en therapeutique. |
AU2007283113A1 (en) | 2006-08-08 | 2008-02-14 | Sanofi-Aventis | Arylaminoaryl-alkyl-substituted imidazolidine-2,4-diones, processes for preparing them, medicaments comprising these compounds, and their use |
EP2025674A1 (de) | 2007-08-15 | 2009-02-18 | sanofi-aventis | Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
FR2930939B1 (fr) * | 2008-05-09 | 2010-07-30 | Sanofi Aventis | Derives de pyrrole, leur preparation et leur application en therapeutique |
UY31968A (es) | 2008-07-09 | 2010-01-29 | Sanofi Aventis | Nuevos derivados heterocíclicos, sus procesos para su preparación, y sus usos terapéuticos |
WO2010068601A1 (en) | 2008-12-08 | 2010-06-17 | Sanofi-Aventis | A crystalline heteroaromatic fluoroglycoside hydrate, processes for making, methods of use and pharmaceutical compositions thereof |
KR20120060207A (ko) | 2009-08-26 | 2012-06-11 | 사노피 | 신규한 결정성 헤테로방향족 플루오로글리코시드 수화물, 이들 화합물을 포함하는 약제 및 이들의 용도 |
EP2582709B1 (de) | 2010-06-18 | 2018-01-24 | Sanofi | Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen |
GB201103419D0 (es) | 2011-02-28 | 2011-04-13 | Univ Aberdeen | |
WO2012120052A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung |
EP2683700B1 (de) | 2011-03-08 | 2015-02-18 | Sanofi | Tetrasubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
US8828995B2 (en) | 2011-03-08 | 2014-09-09 | Sanofi | Branched oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof |
US8710050B2 (en) | 2011-03-08 | 2014-04-29 | Sanofi | Di and tri- substituted oxathiazine derivatives, method for the production, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof |
EP2683705B1 (de) | 2011-03-08 | 2015-04-22 | Sanofi | Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
US8889730B2 (en) | 2012-04-10 | 2014-11-18 | Pfizer Inc. | Indole and indazole compounds that activate AMPK |
CA2921147C (en) | 2012-08-20 | 2018-01-23 | Thomas M. Espinosa | Anchor holders and anchor assemblies for metal decks |
EP2970177A1 (en) | 2013-03-15 | 2016-01-20 | Pfizer Inc. | Indole compounds that activate ampk |
EP3206683A4 (en) | 2014-10-16 | 2018-06-13 | The Board of Trustees of the Leland Stanford Junior University | Novel methods, compounds, and compositions for anesthesia |
CN104496879A (zh) * | 2015-01-13 | 2015-04-08 | 佛山市赛维斯医药科技有限公司 | 一种含腈基苯和二烯氟代金刚烷结构的化合物和用途 |
CN104447485A (zh) * | 2015-01-13 | 2015-03-25 | 佛山市赛维斯医药科技有限公司 | 一种含腈基苯和二烯金刚烷结构的化合物、其制备方法和用途 |
CN104447484B (zh) * | 2015-01-13 | 2016-06-08 | 佛山市赛维斯医药科技有限公司 | 含烷氧苯基和二烯金刚烷结构的化合物、其制备方法和用途 |
CN104478782B (zh) * | 2015-01-13 | 2016-03-16 | 佛山市赛维斯医药科技有限公司 | 一类含烷氧苯基和二烯氟代金刚烷结构的化合物和用途 |
CN104478781A (zh) * | 2015-01-13 | 2015-04-01 | 佛山市赛维斯医药科技有限公司 | 二烯金刚烷类化合物、其制备方法和用途 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2692575B1 (fr) * | 1992-06-23 | 1995-06-30 | Sanofi Elf | Nouveaux derives du pyrazole, procede pour leur preparation et compositions pharmaceutiques les contenant. |
GB0230088D0 (en) * | 2002-12-24 | 2003-01-29 | Astrazeneca Ab | Therapeutic agents |
-
2005
- 2005-02-17 FR FR0501660A patent/FR2882054B1/fr not_active Expired - Fee Related
-
2006
- 2006-02-14 UY UY29373A patent/UY29373A1/es not_active Application Discontinuation
- 2006-02-15 AR ARP060100534A patent/AR052673A1/es unknown
- 2006-02-16 JP JP2007555665A patent/JP2008530187A/ja not_active Withdrawn
- 2006-02-16 RU RU2007134383/04A patent/RU2007134383A/ru not_active Application Discontinuation
- 2006-02-16 TW TW095105264A patent/TW200714585A/zh unknown
- 2006-02-16 CN CNA2006800049971A patent/CN101119967A/zh active Pending
- 2006-02-16 EP EP06709331A patent/EP1853557A2/fr not_active Withdrawn
- 2006-02-16 KR KR1020077018738A patent/KR20070103454A/ko not_active Application Discontinuation
- 2006-02-16 CA CA002597033A patent/CA2597033A1/fr not_active Abandoned
- 2006-02-16 WO PCT/FR2006/000356 patent/WO2006087476A2/fr active Application Filing
- 2006-02-16 BR BRPI0608866-0A patent/BRPI0608866A2/pt not_active IP Right Cessation
- 2006-02-16 AU AU2006215521A patent/AU2006215521A1/en not_active Abandoned
- 2006-02-17 PA PA20068663601A patent/PA8663601A1/es unknown
- 2006-02-17 DO DO2006000043A patent/DOP2006000043A/es unknown
- 2006-02-17 SV SV2006002420A patent/SV2007002420A/es unknown
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2007
- 2007-08-02 US US11/832,851 patent/US7524971B2/en not_active Expired - Fee Related
- 2007-08-02 IL IL185034A patent/IL185034A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
JP2008530187A (ja) | 2008-08-07 |
IL185034A0 (en) | 2008-06-05 |
CA2597033A1 (fr) | 2006-08-24 |
TW200714585A (en) | 2007-04-16 |
FR2882054A1 (fr) | 2006-08-18 |
RU2007134383A (ru) | 2009-03-27 |
SV2007002420A (es) | 2007-01-17 |
AU2006215521A1 (en) | 2006-08-24 |
WO2006087476A3 (fr) | 2007-08-09 |
KR20070103454A (ko) | 2007-10-23 |
US20080015245A1 (en) | 2008-01-17 |
BRPI0608866A2 (pt) | 2010-02-02 |
CN101119967A (zh) | 2008-02-06 |
AR052673A1 (es) | 2007-03-28 |
DOP2006000043A (es) | 2006-08-31 |
EP1853557A2 (fr) | 2007-11-14 |
UY29373A1 (es) | 2006-10-02 |
WO2006087476A2 (fr) | 2006-08-24 |
US7524971B2 (en) | 2009-04-28 |
FR2882054B1 (fr) | 2007-04-13 |
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