OA12464A - Broadspectrum 2-(substituted-amino)-benzoxazole sulfonamide HIV protease inhibitors. - Google Patents
Broadspectrum 2-(substituted-amino)-benzoxazole sulfonamide HIV protease inhibitors. Download PDFInfo
- Publication number
- OA12464A OA12464A OA1200300253A OA1200300253A OA12464A OA 12464 A OA12464 A OA 12464A OA 1200300253 A OA1200300253 A OA 1200300253A OA 1200300253 A OA1200300253 A OA 1200300253A OA 12464 A OA12464 A OA 12464A
- Authority
- OA
- OAPI
- Prior art keywords
- alkyl
- het1
- het2
- aryl
- amino
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01201308 | 2001-04-09 | ||
| US28770401P | 2001-05-02 | 2001-05-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| OA12464A true OA12464A (en) | 2006-05-24 |
Family
ID=26076876
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| OA1200300253A OA12464A (en) | 2001-04-09 | 2002-04-09 | Broadspectrum 2-(substituted-amino)-benzoxazole sulfonamide HIV protease inhibitors. |
Country Status (25)
| Country | Link |
|---|---|
| US (2) | US7244752B2 (et) |
| EP (1) | EP1397367A2 (et) |
| JP (1) | JP4417010B2 (et) |
| KR (1) | KR100872029B1 (et) |
| CN (1) | CN100491360C (et) |
| AP (1) | AP1544A (et) |
| AR (1) | AR035819A1 (et) |
| AU (1) | AU2002257774B2 (et) |
| BG (1) | BG66371B1 (et) |
| BR (1) | BR0208796A (et) |
| CA (1) | CA2442870C (et) |
| CZ (1) | CZ303139B6 (et) |
| EA (1) | EA007383B1 (et) |
| EE (1) | EE05384B1 (et) |
| HR (1) | HRP20030905B1 (et) |
| HU (1) | HUP0303744A3 (et) |
| IL (1) | IL158092A0 (et) |
| MX (1) | MXPA03009179A (et) |
| NO (1) | NO328896B1 (et) |
| NZ (1) | NZ528954A (et) |
| OA (1) | OA12464A (et) |
| PL (1) | PL367084A1 (et) |
| SK (1) | SK288232B6 (et) |
| WO (1) | WO2002081478A2 (et) |
| ZA (1) | ZA200307683B (et) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1397367A2 (en) * | 2001-04-09 | 2004-03-17 | Tibotec Pharmaceuticals Ltd. | Broadspectrum 2-(substituted-amino)-benzoxazole sulfonamide hiv protease inhibitors |
| NZ529250A (en) * | 2001-05-11 | 2005-05-27 | Tibotec Pharm Ltd | Broadspectrum 2-amino-benzoxazole sulfonamide HIV protease inhibitors |
| US7285566B2 (en) * | 2002-01-07 | 2007-10-23 | Erickson John W | Resistance-repellent retroviral protease inhibitors |
| CA2473231A1 (en) | 2002-01-07 | 2003-08-07 | Sequoia Pharmaceuticals | Resistance-repellent retroviral protease inhibitors |
| US7157489B2 (en) | 2002-03-12 | 2007-01-02 | The Board Of Trustees Of The University Of Illinois | HIV protease inhibitors |
| CA2485903C (en) * | 2002-05-17 | 2011-08-16 | Tibotec Pharmaceuticals Ltd. | Broadspectrum substituted benzisoxazole sulfonamide hiv protease inhibitors |
| CN1953964A (zh) * | 2004-03-11 | 2007-04-25 | 塞阔伊亚药品公司 | 抗耐药性反转录病毒蛋白酶抑制剂 |
| EP1750696B1 (en) * | 2004-05-07 | 2013-06-26 | Sequoia Pharmaceuticals Inc | RETROVIRAL PROTEASE INHIBITORS RESISTING THEIR RESISTANCE |
| BRPI0607827B8 (pt) | 2005-02-25 | 2021-05-25 | Janssen R & D Ireland | composto precursor de inibidor de protease, processo para a produção do referido composto e seu uso |
| DE102010044584A1 (de) * | 2010-09-07 | 2012-03-08 | Kautex Textron Gmbh & Co. Kg | Kraftstoffbehälter aus thermoplastischem Kunststoff |
| WO2014194519A1 (en) | 2013-06-07 | 2014-12-11 | Merck Sharp & Dohme Corp. | Imidazole derivatives and methods of use thereof for improving pharmacokinetics of drug |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3021326A1 (de) | 1980-06-06 | 1981-12-17 | Drägerwerk AG, 2400 Lübeck | Einrichtung zur messung von mindestens zwei pneumatischen lungenparametern und messverfahren hierzu |
| US4448192A (en) * | 1982-03-05 | 1984-05-15 | Hewlett Packard Company | Medical ventilator device parametrically controlled for patient ventilation |
| IT1185906B (it) * | 1985-09-13 | 1987-11-18 | Luciano Gattinoni | Sistema ed apparecchio biomedicale per la misurazione con precisione dei valori di variazione di pressione e volume nei polmoni di un paziente |
| US5136043A (en) * | 1989-06-17 | 1992-08-04 | Hoechst Aktiengesellschaft | Process for the preparation of aromatic sulfonyl chlorides |
| DE3919840A1 (de) | 1989-06-17 | 1991-01-17 | Hoechst Ag | Verfahren zur herstellung von aromatischen sulfonsaeurechloriden |
| ES2093073T3 (es) | 1990-03-09 | 1996-12-16 | Milliken Res Corp | Materiales organicos que tienen restos poli(oxialquilenos) enlazados por un grupo sulfonamido y su preparacion. |
| US5145684A (en) | 1991-01-25 | 1992-09-08 | Sterling Drug Inc. | Surface modified drug nanoparticles |
| PH30929A (en) | 1992-09-03 | 1997-12-23 | Janssen Pharmaceutica Nv | Beads having a core coated with an antifungal and a polymer. |
| IS2334B (is) * | 1992-09-08 | 2008-02-15 | Vertex Pharmaceuticals Inc., (A Massachusetts Corporation) | Aspartyl próteasi hemjari af nýjum flokki súlfonamíða |
| DK0715618T3 (da) * | 1993-08-24 | 1999-08-23 | Searle & Co | Hydroxyethylaminosulfonamider til anvendelse som inhibitorer af retrovirale proteaser |
| CZ289214B6 (cs) | 1993-10-01 | 2001-12-12 | Astra Aktiebolag | Způsob zpracování jemně děleného práąkového léčiva, zařízení k provádění tohoto způsobu a aglomeráty vyrobené tímto způsobem |
| ATE214046T1 (de) | 1993-11-23 | 2002-03-15 | Searle & Co | Verfahren zur herstellung von zwischenprodukten, die für die herstellung von retroviral-protease hemmenden verbindungen verwendbar sind |
| US6143747A (en) * | 1995-01-20 | 2000-11-07 | G. D. Searle & Co. | Bis-sulfonamide hydroxyethylamino retroviral protease inhibitors |
| US5756533A (en) | 1995-03-10 | 1998-05-26 | G.D. Searle & Co. | Amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors |
| WO1996028465A1 (en) * | 1995-03-10 | 1996-09-19 | G.D. Searle & Co. | Heterocyclecarbonyl amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors |
| US5705500A (en) * | 1995-03-10 | 1998-01-06 | G.D. Searle & Co. | Sulfonylalkanoylamino hydroxyethylamino sulfonamide retroviral protease inhibitors |
| US6150556A (en) * | 1995-03-10 | 2000-11-21 | G. D. Dearle & Co. | Bis-amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors |
| US5691372A (en) * | 1995-04-19 | 1997-11-25 | Vertex Pharmaceuticals Incorporated | Oxygenated-Heterocycle containing sulfonamide inhibitors of aspartyl protease |
| CA2236236A1 (en) * | 1995-11-15 | 1997-05-22 | G.D. Searle & Co. | Substituted sulfonylalkanoylamino hydroxyethylamino sulfonamide retroviral protease inhibitors |
| GB9525994D0 (en) | 1995-12-20 | 1996-02-21 | Univ Manitoba | Improvements in delivery of assist modes of mechanical ventilation |
| BR9706897B1 (pt) | 1996-05-20 | 2010-09-21 | forma de dosagem farmacêutica. | |
| ES2201485T3 (es) | 1997-03-26 | 2004-03-16 | Janssen Pharmaceutica N.V. | Palets que tienen un nucleo recubierto con un agente antifungico y un polimero. |
| SE513969C2 (sv) * | 1997-05-17 | 2000-12-04 | Draegerwerk Ag | Anordning och förfarande för bestämning av respirationssystemetsmekaniska egenskaper |
| WO1999006254A1 (de) * | 1997-07-31 | 1999-02-11 | Continental Teves Ag & Co. Ohg | Verfahren und vorrichtung zur aktivierung einer bremsanlage |
| AU2092599A (en) | 1997-12-24 | 1999-07-19 | Vertex Pharmaceuticals Incorporated | Prodrugs of aspartyl protease inhibitors |
| US6436989B1 (en) | 1997-12-24 | 2002-08-20 | Vertex Pharmaceuticals, Incorporated | Prodrugs of aspartyl protease inhibitors |
| AU2012199A (en) | 1997-12-24 | 1999-07-19 | Vertex Pharmaceuticals Incorporated | Prodrugs of aspartyl protease inhibitors |
| AU2010299A (en) | 1997-12-24 | 1999-07-19 | Vertex Pharmaceuticals Incorporated | Prodrugs os aspartyl protease inhibitors |
| AU4828199A (en) * | 1998-06-23 | 2000-01-10 | Board Of Trustees Of The University Of Illinois, The | Multi-drug resistant retroviral protease inhibitors and associated methods |
| PT2336134T (pt) | 1998-06-23 | 2016-10-19 | The Board Of Trustees Of The Univ Of Illionis | Ensaio de aptidão e métodos para reduzir a resistência do hiv à terapia |
| SK287153B6 (sk) * | 1999-10-06 | 2010-01-07 | Tibotec Pharmaceuticals Ltd. | Hexahydrofuro[2,3-b]furan-3-yl-N-{3-[(1,3-benzodioxol-5- ylsulfonyl)(izobutyl)amino]1-benzyl-2-hydroxypropyl}karbamát, jeho použitie a farmaceutický prípravok s jeho obsahom |
| EP1397367A2 (en) * | 2001-04-09 | 2004-03-17 | Tibotec Pharmaceuticals Ltd. | Broadspectrum 2-(substituted-amino)-benzoxazole sulfonamide hiv protease inhibitors |
-
2002
- 2002-04-09 EP EP02727554A patent/EP1397367A2/en not_active Withdrawn
- 2002-04-09 KR KR1020037013144A patent/KR100872029B1/ko not_active IP Right Cessation
- 2002-04-09 EA EA200301110A patent/EA007383B1/ru not_active IP Right Cessation
- 2002-04-09 HU HU0303744A patent/HUP0303744A3/hu unknown
- 2002-04-09 WO PCT/EP2002/004012 patent/WO2002081478A2/en active IP Right Grant
- 2002-04-09 NZ NZ528954A patent/NZ528954A/en not_active IP Right Cessation
- 2002-04-09 AU AU2002257774A patent/AU2002257774B2/en not_active Ceased
- 2002-04-09 US US10/474,162 patent/US7244752B2/en not_active Expired - Fee Related
- 2002-04-09 BR BR0208796-0A patent/BR0208796A/pt not_active IP Right Cessation
- 2002-04-09 AP APAP/P/2003/002882A patent/AP1544A/en active
- 2002-04-09 CZ CZ20032936A patent/CZ303139B6/cs not_active IP Right Cessation
- 2002-04-09 AR ARP020101301A patent/AR035819A1/es not_active Application Discontinuation
- 2002-04-09 JP JP2002579466A patent/JP4417010B2/ja not_active Expired - Fee Related
- 2002-04-09 IL IL15809202A patent/IL158092A0/xx not_active IP Right Cessation
- 2002-04-09 PL PL02367084A patent/PL367084A1/xx unknown
- 2002-04-09 CN CNB028114809A patent/CN100491360C/zh not_active Expired - Fee Related
- 2002-04-09 EE EEP200300494A patent/EE05384B1/et not_active IP Right Cessation
- 2002-04-09 OA OA1200300253A patent/OA12464A/en unknown
- 2002-04-09 CA CA2442870A patent/CA2442870C/en not_active Expired - Fee Related
- 2002-04-09 SK SK1339-2003A patent/SK288232B6/sk not_active IP Right Cessation
- 2002-04-09 MX MXPA03009179A patent/MXPA03009179A/es active IP Right Grant
-
2003
- 2003-10-01 BG BG108218A patent/BG66371B1/bg unknown
- 2003-10-01 ZA ZA2003/07683A patent/ZA200307683B/en unknown
- 2003-10-08 NO NO20034505A patent/NO328896B1/no not_active IP Right Cessation
- 2003-11-07 HR HR20030905A patent/HRP20030905B1/xx not_active IP Right Cessation
-
2007
- 2007-01-23 US US11/626,183 patent/US7595334B2/en not_active Expired - Fee Related
Also Published As
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