NZ602955A - Pharmaceutical composition comprising efavirenz - Google Patents

Pharmaceutical composition comprising efavirenz

Info

Publication number
NZ602955A
NZ602955A NZ602955A NZ60295511A NZ602955A NZ 602955 A NZ602955 A NZ 602955A NZ 602955 A NZ602955 A NZ 602955A NZ 60295511 A NZ60295511 A NZ 60295511A NZ 602955 A NZ602955 A NZ 602955A
Authority
NZ
New Zealand
Prior art keywords
efavirenz
particles
pharmaceutical composition
micrometre
particle size
Prior art date
Application number
NZ602955A
Other languages
English (en)
Inventor
Amar Lulla
Geena Malhotra
Original Assignee
Cipla Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cipla Ltd filed Critical Cipla Ltd
Publication of NZ602955A publication Critical patent/NZ602955A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/536—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with carbocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NZ602955A 2010-04-20 2011-04-20 Pharmaceutical composition comprising efavirenz NZ602955A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN1296MU2010 2010-04-20
PCT/GB2011/000620 WO2011131943A2 (en) 2010-04-20 2011-04-20 Pharmaceutical compositions

Publications (1)

Publication Number Publication Date
NZ602955A true NZ602955A (en) 2015-02-27

Family

ID=44625957

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ602955A NZ602955A (en) 2010-04-20 2011-04-20 Pharmaceutical composition comprising efavirenz

Country Status (13)

Country Link
US (1) US20130302415A1 (enExample)
EP (1) EP2560617A2 (enExample)
JP (1) JP2013525337A (enExample)
KR (1) KR20130076818A (enExample)
CN (1) CN102985072A (enExample)
AU (1) AU2011244783B2 (enExample)
BR (1) BR112012026843A2 (enExample)
CA (1) CA2796494A1 (enExample)
GT (1) GT201200284A (enExample)
NZ (1) NZ602955A (enExample)
RU (1) RU2012149115A (enExample)
WO (1) WO2011131943A2 (enExample)
ZA (1) ZA201207670B (enExample)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201115633D0 (en) * 2011-09-09 2011-10-26 Univ Liverpool Compositions of efavirenz
US10646452B2 (en) * 2013-03-15 2020-05-12 New Jersey Institute Of Technology System and method for fabrication of uniform polymer films containing nano and micro particles via continuous drying process
IN2013MU03370A (enExample) 2013-10-25 2015-09-25 Cipla Ltd
WO2015071841A1 (en) 2013-11-12 2015-05-21 Druggability Technologies Holdings Limited Complexes of dabigatran and its derivatives, process for the preparation thereof and pharmaceutical compositions containing them
WO2015140569A1 (en) * 2014-03-20 2015-09-24 Cipla Limited Pharmaceutical composition
CN104224790A (zh) * 2014-09-28 2014-12-24 苏州普罗达生物科技有限公司 一种依法韦仑组合物及其制备方法
PE20180690A1 (es) 2015-04-27 2018-04-23 Intercept Pharmaceuticals Inc Composiciones de acido obeticolico y metodos de uso
GB201515387D0 (en) * 2015-08-28 2015-10-14 Amazentis Sa Compositions
GB201515391D0 (en) * 2015-08-28 2015-10-14 Amazentis Sa Compositions
AU2017364077A1 (en) 2016-11-22 2019-06-20 Elektrofi, Inc. Particles comprising a therapeutic or diagnostic agent and suspensions and methods of use thereof
WO2019023392A1 (en) 2017-07-25 2019-01-31 Elektrofi, Inc. FORMATION OF PARTICLES COMPRISING AGENTS
US20230040901A1 (en) * 2018-01-04 2023-02-09 PlantTec Medical GmbH Pharmaceutical composition for inhibiting postoperative adhesions
ES2732498B2 (es) * 2018-05-21 2020-04-27 Consejo Superior Investigacion Uso de efavirenz para el tratamiento de enfermedades de almacenamiento lipidico.
WO2019226969A1 (en) 2018-05-24 2019-11-28 Elektrofi, Inc. Particles comprising a therapeutic or diagnostic agent and suspensions and methods of use thereof
CN112236141A (zh) * 2018-06-11 2021-01-15 大塚制药株式会社 包含德拉马尼的组合物
AU2020214626B2 (en) 2019-01-31 2025-10-16 Halozyme Hypercon, Inc. Particle formation and morphology
AU2020344675B2 (en) 2019-09-13 2026-06-25 Halozyme Hypercon, Inc. Compositions and methods for the delivery of therapeutic biologics for treatment of disease
KR20220109430A (ko) 2019-12-02 2022-08-04 아스트라제네카 아베 6-(2-클로로-6-메틸피리딘-4-일)-5-(4-플루오로페닐)-1,2,4-트리아진-3-아민의 고체 약학 제형
US12377050B2 (en) 2020-04-17 2025-08-05 Elektrofi, Inc. Methods of forming particles by continuous droplet formation and dehydration
WO2021216475A1 (en) * 2020-04-20 2021-10-28 Poviva Corp. Compositions and methods for enhanced delivery of antiviral agents
CN112245400B (zh) * 2020-11-10 2023-01-20 蓝龙药业(北京)有限公司 一种依法韦仑微片剂、制备方法及其应用
CN114404377B (zh) * 2022-01-10 2023-07-25 安徽贝克生物制药有限公司 一种阿巴卡韦、拉米夫定、依非韦伦复方片及其制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA72207C2 (uk) * 1998-04-07 2005-02-15 Брістол- Майєрс Сквібб Фарма Компані Фармацевтична композиція ефавіренцу з добавкою дезінтегруючих агентів у вигляді швидкорозчинних капсул або таблеток та спосіб її виготовлення
EP1332757B1 (en) * 1998-05-27 2012-06-13 Merck Sharp & Dohme Corp. Efavirenz compressed tablet formulation
PE20000559A1 (es) 1998-05-27 2000-07-05 Merck & Co Inc Formulacion de tabletas comprimidas de efavirenz
AU2002359518A1 (en) * 2001-11-27 2003-06-10 Bristol-Myers Squibb Company Efavirenz tablet formulation having unique biopharmaceutical characteristics
US20070003623A1 (en) * 2005-06-29 2007-01-04 Wyeth Formulations of conjugated estrogens and bazedoxifene
US20080026062A1 (en) * 2006-07-31 2008-01-31 Isaac Farr Pharmaceutical compositions including nano-sized active agent
TWI405590B (zh) * 2007-04-06 2013-08-21 活效製藥股份有限公司 微粉碎化有機化合物粒子之製法
CA2697150A1 (en) * 2007-08-17 2009-02-26 Teva Pharmaceutical Industries Ltd. Methods and compositions for controlling the bioavailability of poorly soluble drugs
JP4606444B2 (ja) * 2007-08-21 2011-01-05 アピ株式会社 アントシアニン含有経口投与用組成物及びその製造方法
WO2010068899A1 (en) * 2008-12-12 2010-06-17 Creighton University Nanoparticles comprising combinations of antiretroviral agents and use thereof
US10952965B2 (en) * 2009-05-15 2021-03-23 Baxter International Inc. Compositions and methods for drug delivery
GB201006038D0 (en) * 2010-04-12 2010-05-26 Unilever Plc Improvements relating to antiviral compositions

Also Published As

Publication number Publication date
KR20130076818A (ko) 2013-07-08
RU2012149115A (ru) 2014-05-27
BR112012026843A2 (pt) 2016-07-12
EP2560617A2 (en) 2013-02-27
CN102985072A (zh) 2013-03-20
WO2011131943A2 (en) 2011-10-27
GT201200284A (es) 2014-08-26
WO2011131943A8 (en) 2012-11-29
US20130302415A1 (en) 2013-11-14
AU2011244783A1 (en) 2012-11-01
WO2011131943A3 (en) 2011-12-29
CA2796494A1 (en) 2011-10-27
ZA201207670B (en) 2013-05-29
AU2011244783B2 (en) 2015-11-12
JP2013525337A (ja) 2013-06-20

Similar Documents

Publication Publication Date Title
NZ607935A (en) Pharmaceutical compositions comprising rifaximin
AU2010279931B2 (en) Composition and process for production thereof
NZ741873A (en) Pharmaceutical nanoparticles showing improved mucosal transport
WO2013132457A3 (en) Nanocrystalline solid dispersion compositions and process of preparation thereof
EP4403172A3 (en) Polyvinylpyrrolidone for the stabilization of a solid dispersion of the non-crystalline form of rotigotine
WO2011112900A3 (en) Intravenous formulations of coenzyme q10 (coq10) and methods of use thereof
MX2012006401A (es) Proceso para preparar composiciones oftalmicas farmaceuticas.
AU2013293116A8 (en) Alpha (1,2) fucosyltransferases suitable for use in the production of fucosylated oligosaccharides
AU2011336397A8 (en) Chemokine CXCR4 receptor modulators and uses related thereto
WO2010121082A3 (en) Emulsions of perfluorocarbons
WO2012051426A3 (en) Aggregate nanoparticulate medicament formulations, manufacture and use thereof
MX2011012196A (es) Composiciones y metodos para el suministro de farmaco.
NZ595904A (en) A novel formulation of meloxicam
EP4218718A3 (en) Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same
MY159208A (en) A novel formulation of indomethacin
BR112013026362A2 (pt) partículas com revestimento de polímero vinílico de hidroxila sensível à força iônica
NZ723631A (en) Nanosuspension of natural materials and preparation method thereof
BRPI0810838A2 (pt) Processo para preparar uma dispersão aquosa de partículas, dispersão aquosa de partículas compósitas, uso de uma dispersão aquosa de partículas compósitas, e, pó de compósito-particula
MX362931B (es) Granulo dispersable en agua, y metodo para producir el mismo.
AU2014226192A8 (en) Dry pharmaceutical compositions comprising active agent nanoparticles bound to carrier particles
NZ598833A (en) Antimicrobial and wound-healing action pharmaceutical composition for external application process of producing the same
BR112015007883A2 (pt) pré-floculação de enchedores usados na fabricação de papel
WO2017036916A8 (en) Process to manufacture cross-linked enzyme aggregates
BR112013032841A8 (pt) Método para a produção de pós para inalação
WO2011146852A3 (en) Foam or particles for applications such as drug delivery

Legal Events

Date Code Title Description
PSEA Patent sealed
RENW Renewal (renewal fees accepted)

Free format text: PATENT RENEWED FOR 3 YEARS UNTIL 20 APR 2018 BY BALDWINS INTELLECTUAL PROPERTY

Effective date: 20150910

LAPS Patent lapsed