NZ602175A - Aberrant mitochondrial dna, associated fusion transcripts and hybridization probes therefor - Google Patents

Aberrant mitochondrial dna, associated fusion transcripts and hybridization probes therefor

Info

Publication number
NZ602175A
NZ602175A NZ602175A NZ60217509A NZ602175A NZ 602175 A NZ602175 A NZ 602175A NZ 602175 A NZ602175 A NZ 602175A NZ 60217509 A NZ60217509 A NZ 60217509A NZ 602175 A NZ602175 A NZ 602175A
Authority
NZ
New Zealand
Prior art keywords
hybridization probes
mitochondrial dna
fusion transcripts
associated fusion
aberrant mitochondrial
Prior art date
Application number
NZ602175A
Other languages
English (en)
Inventor
Ryan Parr
Brian Reguly
Gabriel Dakubo
Jennifer Creed
Kerry Robinson
Original Assignee
Mitomics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitomics Inc filed Critical Mitomics Inc
Publication of NZ602175A publication Critical patent/NZ602175A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869Methods for sequencing
    • C12Q1/6874Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B30/00Methods of screening libraries
    • C40B30/04Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Peptides Or Proteins (AREA)
NZ602175A 2008-03-28 2009-03-27 Aberrant mitochondrial dna, associated fusion transcripts and hybridization probes therefor NZ602175A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4061608P 2008-03-28 2008-03-28
NZ588658A NZ588658A (en) 2008-03-28 2009-03-27 Aberrant mitochondrial dna, associated fusion transcripts and hybridization probes therefor

Publications (1)

Publication Number Publication Date
NZ602175A true NZ602175A (en) 2014-03-28

Family

ID=41112880

Family Applications (2)

Application Number Title Priority Date Filing Date
NZ602175A NZ602175A (en) 2008-03-28 2009-03-27 Aberrant mitochondrial dna, associated fusion transcripts and hybridization probes therefor
NZ588658A NZ588658A (en) 2008-03-28 2009-03-27 Aberrant mitochondrial dna, associated fusion transcripts and hybridization probes therefor

Family Applications After (1)

Application Number Title Priority Date Filing Date
NZ588658A NZ588658A (en) 2008-03-28 2009-03-27 Aberrant mitochondrial dna, associated fusion transcripts and hybridization probes therefor

Country Status (10)

Country Link
US (4) US20110172113A1 (fr)
EP (1) EP2274426B1 (fr)
JP (1) JP5938690B2 (fr)
KR (2) KR101693387B1 (fr)
CN (3) CN107011428B (fr)
AU (1) AU2009227935B2 (fr)
CA (2) CA3044262C (fr)
NZ (2) NZ602175A (fr)
SG (3) SG192453A1 (fr)
WO (1) WO2009117811A1 (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009117811A1 (fr) * 2008-03-28 2009-10-01 Genesis Genomics Inc. Adn mitochondrial aberrant, produits de transcription de fusion associés et sondes d’hybridation pour celui-ci
EP2411522B1 (fr) * 2009-03-27 2017-09-06 MDNA Life Sciences Inc. Adn mitochondrial aberrant, transcrits de fusion et produits de traduction associes et sondes d'hybridation complementaires
WO2011106892A1 (fr) * 2010-03-01 2011-09-09 Mitomics Inc. Produits de transcription de fusion d'adn-mt associés aux uv et méthodes et utilisations de ceux-ci
US9850296B2 (en) 2010-08-10 2017-12-26 Ecole Polytechnique Federale De Lausanne (Epfl) Erythrocyte-binding therapeutics
JP6017422B2 (ja) 2010-08-10 2016-11-02 エコール・ポリテクニーク・フェデラル・ドゥ・ローザンヌ(ウペエフエル)Ecole Polytechnique Federale de Lausanne (EPFL) 赤血球結合療法
US9517257B2 (en) 2010-08-10 2016-12-13 Ecole Polytechnique Federale De Lausanne (Epfl) Erythrocyte-binding therapeutics
US10946079B2 (en) 2014-02-21 2021-03-16 Ecole Polytechnique Federale De Lausanne Glycotargeting therapeutics
US10953101B2 (en) 2014-02-21 2021-03-23 École Polytechnique Fédérale De Lausanne (Epfl) Glycotargeting therapeutics
JP6744227B2 (ja) 2014-02-21 2020-08-19 エコール・ポリテクニーク・フェデラル・ドゥ・ローザンヌ(ウペエフエル)Ecole Polytechnique Federale de Lausanne (EPFL) 糖標的化治療剤
US10046056B2 (en) 2014-02-21 2018-08-14 École Polytechnique Fédérale De Lausanne (Epfl) Glycotargeting therapeutics
AU2017280210A1 (en) * 2016-06-22 2019-01-24 Degen Zhuo Method and kit for detecting fusion transcripts
WO2018144782A1 (fr) * 2017-02-01 2018-08-09 The Translational Genomics Research Institute Procédés de détection de variants somatiques et de lignée germinale dans des tumeurs impures
WO2018232176A1 (fr) 2017-06-16 2018-12-20 The University Of Chicago Compositions et procédés d'induction d'une tolérance immunitaire
WO2019191079A1 (fr) * 2018-03-26 2019-10-03 The University Of Chicago Procédés et compositions permettant de cibler une lectine de type c de cellules endothéliales sinusoïdales du foie et des ganglions lymphatiques (lsectine)
CN117384269A (zh) * 2023-09-21 2024-01-12 南方医科大学南方医院 短肽mfrlp及其在制备动脉重塑相关疾病药物中的应用

Family Cites Families (22)

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NL154598B (nl) * 1970-11-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking.
US3817837A (en) * 1971-05-14 1974-06-18 Syva Corp Enzyme amplification assay
US3939350A (en) * 1974-04-29 1976-02-17 Board Of Trustees Of The Leland Stanford Junior University Fluorescent immunoassay employing total reflection for activation
US3996345A (en) * 1974-08-12 1976-12-07 Syva Company Fluorescence quenching with immunological pairs in immunoassays
US4277437A (en) * 1978-04-05 1981-07-07 Syva Company Kit for carrying out chemically induced fluorescence immunoassay
US4275149A (en) * 1978-11-24 1981-06-23 Syva Company Macromolecular environment control in specific receptor assays
US4366241A (en) * 1980-08-07 1982-12-28 Syva Company Concentrating zone method in heterogeneous immunoassays
US5807522A (en) * 1994-06-17 1998-09-15 The Board Of Trustees Of The Leland Stanford Junior University Methods for fabricating microarrays of biological samples
US6605433B1 (en) * 1998-08-20 2003-08-12 The Johns Hopkins University Mitochondrial dosimeter
US6203990B1 (en) * 1998-11-06 2001-03-20 Mitokor Method and system for pattern analysis, such as for analyzing oligonucleotide primer extension assay products
US6933120B2 (en) * 2000-06-20 2005-08-23 Michael D. Seidman Method of determining biological/molecular age
CA2450403A1 (fr) * 2001-06-11 2002-12-19 1304854 Ontario Ltd. Sequences completes du genome mitochondrial servant d'outil diagnostique dans les sciences de la sante
US20030162174A1 (en) * 2001-06-11 2003-08-28 Sutherland John W. Detecting nucleic acid deletion sequences
US20050026167A1 (en) * 2001-06-11 2005-02-03 Mark Birch-Machin Complete mitochondrial genome sequences as a diagnostic tool for the health sciences
GB2380194B (en) * 2001-10-01 2005-06-22 Roger Michael Marchbanks A mitochondrial mutation associated with schizophrenia and increased oxidative stress
US20060051796A1 (en) * 2004-09-09 2006-03-09 Inga Boell Real time PCR with the addition of pyrophosphatase
KR101363032B1 (ko) * 2005-04-18 2014-02-13 미토믹스 인크. 일광 노출, 전립선암 및 다른 암의 검출용 진단 도구로서미토콘드리아 돌연변이 및 전위
US20070134678A1 (en) * 2005-12-12 2007-06-14 Rees Dianne M Comparative genome hybridization of organelle genomes
CN101874119B (zh) 2007-09-26 2015-01-28 米托米克斯公司 3.4kb线粒体DNA缺失用于检测癌症
WO2009117811A1 (fr) 2008-03-28 2009-10-01 Genesis Genomics Inc. Adn mitochondrial aberrant, produits de transcription de fusion associés et sondes d’hybridation pour celui-ci
EP2411522B1 (fr) 2009-03-27 2017-09-06 MDNA Life Sciences Inc. Adn mitochondrial aberrant, transcrits de fusion et produits de traduction associes et sondes d'hybridation complementaires
WO2011106892A1 (fr) * 2010-03-01 2011-09-09 Mitomics Inc. Produits de transcription de fusion d'adn-mt associés aux uv et méthodes et utilisations de ceux-ci

Also Published As

Publication number Publication date
SG10201400985RA (en) 2014-05-29
CN107011428B (zh) 2022-02-25
KR101693387B1 (ko) 2017-01-05
US10266899B2 (en) 2019-04-23
AU2009227935A1 (en) 2009-10-01
US20130059299A1 (en) 2013-03-07
EP2274426A4 (fr) 2011-11-16
AU2009227935B2 (en) 2015-07-09
SG174514A1 (en) 2011-10-28
KR20110004860A (ko) 2011-01-14
CA2719718C (fr) 2019-07-02
JP2011515091A (ja) 2011-05-19
CN102016039B (zh) 2017-06-09
US20170152567A1 (en) 2017-06-01
CA3044262A1 (fr) 2009-10-01
JP5938690B2 (ja) 2016-06-22
SG192453A1 (en) 2013-08-30
KR101819852B1 (ko) 2018-02-28
CN102388140B (zh) 2015-07-08
CA2719718A1 (fr) 2009-10-01
EP2274426A1 (fr) 2011-01-19
WO2009117811A1 (fr) 2009-10-01
US20110172113A1 (en) 2011-07-14
EP2274426B1 (fr) 2016-11-16
US20190382846A1 (en) 2019-12-19
NZ588658A (en) 2012-10-26
US8715960B2 (en) 2014-05-06
KR20170004033A (ko) 2017-01-10
CN107011428A (zh) 2017-08-04
CN102388140A (zh) 2012-03-21
CA3044262C (fr) 2023-02-28
CN102016039A (zh) 2011-04-13

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Owner name: MDNA LIFE SCIENCES INC., 1209 ORANGE STREET, C, US

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