CA2450403A1 - Sequences completes du genome mitochondrial servant d'outil diagnostique dans les sciences de la sante - Google Patents
Sequences completes du genome mitochondrial servant d'outil diagnostique dans les sciences de la sante Download PDFInfo
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- CA2450403A1 CA2450403A1 CA002450403A CA2450403A CA2450403A1 CA 2450403 A1 CA2450403 A1 CA 2450403A1 CA 002450403 A CA002450403 A CA 002450403A CA 2450403 A CA2450403 A CA 2450403A CA 2450403 A1 CA2450403 A1 CA 2450403A1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Hospice & Palliative Care (AREA)
- Biophysics (AREA)
- Oncology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
L'examen de mutations dans l'ensemble du génome mitochondrial sert de système diagnostique pour des maladies telles que le cancer de la prostate et le cancer de la peau sans mélanomes. Des mutations et des réarrangements caractéristiques tels que des mutations ponctuelles (transitions, transversions), délétions, inversions, duplications, recombinaisons, insertions ou des combinaisons de celles-ci dans le génome mitochondrial servent d'indicateurs précoces du cancer de la prostate et du cancer de la peau sans mélanomes. Par ailleurs, 4977bp ou <= délétion commune >= ainsi que d'autres mutations et/ou délétions associées servent de mesure du vieillissement.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US29734001P | 2001-06-11 | 2001-06-11 | |
| US60/297,340 | 2001-06-11 | ||
| PCT/CA2002/000848 WO2002101086A2 (fr) | 2001-06-11 | 2002-06-10 | Sequences completes du genome mitochondrial servant d'outil diagnostique dans les sciences de la sante |
| CA002450004A CA2450004A1 (fr) | 2001-06-11 | 2003-12-18 | Sequences completes du genome mitochondrial comme outil diagnostic pour les sciences de la sante |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2450403A1 true CA2450403A1 (fr) | 2002-12-19 |
Family
ID=34808883
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002450403A Abandoned CA2450403A1 (fr) | 2001-06-11 | 2002-06-10 | Sequences completes du genome mitochondrial servant d'outil diagnostique dans les sciences de la sante |
| CA002450004A Abandoned CA2450004A1 (fr) | 2001-06-11 | 2003-12-18 | Sequences completes du genome mitochondrial comme outil diagnostic pour les sciences de la sante |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002450004A Abandoned CA2450004A1 (fr) | 2001-06-11 | 2003-12-18 | Sequences completes du genome mitochondrial comme outil diagnostic pour les sciences de la sante |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP1397508A2 (fr) |
| JP (1) | JP2005506057A (fr) |
| CA (2) | CA2450403A1 (fr) |
| WO (1) | WO2002101086A2 (fr) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE0200817D0 (sv) * | 2002-03-15 | 2002-03-15 | Ulf Gyllensten | Method and kit for detection of mutations in mitochondrial DNA |
| CA2550135A1 (fr) * | 2003-12-11 | 2005-06-23 | 1304854 Ontario Ltd. | Sequences completes du genome mitochondrial utilisees comme outil de diagnostic pour des sciences de la sante |
| US20130022979A1 (en) | 2005-04-18 | 2013-01-24 | Genesis Genomics Inc. | 3.4kb MITOCHONDRIAL DNA DELETION FOR USE IN THE DETECTION OF CANCER |
| CN103789405B (zh) | 2005-04-18 | 2018-03-30 | Mdna生命科学有限公司 | 作为检测日光照射、前列腺癌和其它癌症的诊断工具的线粒体突变及重排 |
| NZ584815A (en) * | 2007-09-26 | 2012-07-27 | Mitomics Inc | 3.4 kb mitochondrial dna deletion for use in the detection of cancer |
| WO2009059414A1 (fr) * | 2007-11-09 | 2009-05-14 | Genesis Genomics Inc. | Suppression de mutations d'adn mitochondrial entre les résidus 12317-16254 pour une utilisation dans la détection d'un cancer |
| CN107011428B (zh) | 2008-03-28 | 2022-02-25 | Mdna生命科学有限公司 | 异常线粒体dna、相关的融合转录物及其杂交探针 |
| JP5734947B2 (ja) * | 2009-03-27 | 2015-06-17 | ミトミクス インコーポレイテッドＧｅｎｅｓｉｓ Ｇｅｎｏｍｉｃｓ Ｉｎｃ． | 異常型ミトコンドリアｄｎａ、関連融合転写物および翻訳産物、並びにそのハイブリダイゼーションプローブ |
| WO2014038622A1 (fr) * | 2012-09-05 | 2014-03-13 | 国立大学法人大阪大学 | Biomarqueur pour maladies autoimmunes |
| EP2953639B1 (fr) * | 2013-02-06 | 2021-06-02 | Brandeis University | Traitement d'une altération de l'adn et de dysfonctionnement mitochondrial au moyen de jus de fruit de palmier |
| US12012633B2 (en) | 2018-06-11 | 2024-06-18 | The Broad Institute, Inc. | Lineage tracing using mitochondrial genome mutations and single cell genomics |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6605433B1 (en) * | 1998-08-20 | 2003-08-12 | The Johns Hopkins University | Mitochondrial dosimeter |
-
2002
- 2002-06-10 WO PCT/CA2002/000848 patent/WO2002101086A2/fr not_active Application Discontinuation
- 2002-06-10 CA CA002450403A patent/CA2450403A1/fr not_active Abandoned
- 2002-06-10 JP JP2003503836A patent/JP2005506057A/ja active Pending
- 2002-06-10 EP EP02737683A patent/EP1397508A2/fr not_active Withdrawn
-
2003
- 2003-12-18 CA CA002450004A patent/CA2450004A1/fr not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CA2450004A1 (fr) | 2005-06-18 |
| EP1397508A2 (fr) | 2004-03-17 |
| WO2002101086A2 (fr) | 2002-12-19 |
| WO2002101086A3 (fr) | 2003-12-11 |
| JP2005506057A (ja) | 2005-03-03 |
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| FZDE | Discontinued |