NZ602175A - Aberrant mitochondrial dna, associated fusion transcripts and hybridization probes therefor - Google Patents
Aberrant mitochondrial dna, associated fusion transcripts and hybridization probes thereforInfo
- Publication number
- NZ602175A NZ602175A NZ602175A NZ60217509A NZ602175A NZ 602175 A NZ602175 A NZ 602175A NZ 602175 A NZ602175 A NZ 602175A NZ 60217509 A NZ60217509 A NZ 60217509A NZ 602175 A NZ602175 A NZ 602175A
- Authority
- NZ
- New Zealand
- Prior art keywords
- hybridization probes
- mitochondrial dna
- fusion transcripts
- associated fusion
- aberrant mitochondrial
- Prior art date
Links
- 230000004927 fusion Effects 0.000 title abstract 2
- 108020005196 Mitochondrial DNA Proteins 0.000 title 1
- 230000001594 aberrant effect Effects 0.000 title 1
- 238000009396 hybridization Methods 0.000 title 1
- 239000000523 sample Substances 0.000 title 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 230000002438 mitochondrial effect Effects 0.000 abstract 1
- 150000007523 nucleic acids Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
- C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B30/00—Methods of screening libraries
- C40B30/04—Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- Medicinal Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4061608P | 2008-03-28 | 2008-03-28 | |
| NZ588658A NZ588658A (en) | 2008-03-28 | 2009-03-27 | Aberrant mitochondrial dna, associated fusion transcripts and hybridization probes therefor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ602175A true NZ602175A (en) | 2014-03-28 |
Family
ID=41112880
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ602175A NZ602175A (en) | 2008-03-28 | 2009-03-27 | Aberrant mitochondrial dna, associated fusion transcripts and hybridization probes therefor |
| NZ588658A NZ588658A (en) | 2008-03-28 | 2009-03-27 | Aberrant mitochondrial dna, associated fusion transcripts and hybridization probes therefor |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ588658A NZ588658A (en) | 2008-03-28 | 2009-03-27 | Aberrant mitochondrial dna, associated fusion transcripts and hybridization probes therefor |
Country Status (10)
| Country | Link |
|---|---|
| US (4) | US20110172113A1 (enExample) |
| EP (1) | EP2274426B1 (enExample) |
| JP (1) | JP5938690B2 (enExample) |
| KR (2) | KR101693387B1 (enExample) |
| CN (3) | CN102016039B (enExample) |
| AU (1) | AU2009227935B2 (enExample) |
| CA (2) | CA3044262C (enExample) |
| NZ (2) | NZ602175A (enExample) |
| SG (3) | SG192453A1 (enExample) |
| WO (1) | WO2009117811A1 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2274426B1 (en) * | 2008-03-28 | 2016-11-16 | MDNA Life Sciences Inc. | Aberrant mitochondrial dna, associated fusion transcripts and hybridization probes therefor |
| RU2011137486A (ru) * | 2009-03-27 | 2013-05-10 | Митомикс Инк. | Аберрантная митохондриальная днк, ассоциированные с ней слитые транскрипты, продукты трансляции и гибрадизационные зонды |
| US20140024025A1 (en) * | 2010-03-01 | 2014-01-23 | Andrew Harbottle | Uv associated mtdna fusion transcripts and methods and uses thereof |
| US9850296B2 (en) | 2010-08-10 | 2017-12-26 | Ecole Polytechnique Federale De Lausanne (Epfl) | Erythrocyte-binding therapeutics |
| US9517257B2 (en) | 2010-08-10 | 2016-12-13 | Ecole Polytechnique Federale De Lausanne (Epfl) | Erythrocyte-binding therapeutics |
| AU2011289579B2 (en) | 2010-08-10 | 2016-11-17 | Ecole Polytechnique Federale De Lausanne | Erythrocyte-binding therapeutics |
| US10046056B2 (en) | 2014-02-21 | 2018-08-14 | École Polytechnique Fédérale De Lausanne (Epfl) | Glycotargeting therapeutics |
| US10946079B2 (en) | 2014-02-21 | 2021-03-16 | Ecole Polytechnique Federale De Lausanne | Glycotargeting therapeutics |
| LT3107563T (lt) | 2014-02-21 | 2021-07-12 | Ecole Polytechnique Fédérale De Lausanne (Epfl) Epfl-Tto | Gliko-nukreipiantys terapiniai agenai |
| US10953101B2 (en) | 2014-02-21 | 2021-03-23 | École Polytechnique Fédérale De Lausanne (Epfl) | Glycotargeting therapeutics |
| WO2017223194A1 (en) * | 2016-06-22 | 2017-12-28 | Degen Zhuo | Method and kit for detecting fusion transcripts |
| WO2018144782A1 (en) * | 2017-02-01 | 2018-08-09 | The Translational Genomics Research Institute | Methods of detecting somatic and germline variants in impure tumors |
| US11253579B2 (en) | 2017-06-16 | 2022-02-22 | The University Of Chicago | Compositions and methods for inducing immune tolerance |
| WO2019191079A1 (en) * | 2018-03-26 | 2019-10-03 | The University Of Chicago | Methods and compositions for targeting liver and lymph node sinusoidal endothelial cell c-type lectin (lsectin) |
| EA202092723A1 (ru) | 2018-05-09 | 2021-04-09 | Зе Юниверсити Оф Чикаго | Композиции и способы, касающиеся иммунной толерантности |
| EP3899050A2 (en) * | 2018-12-22 | 2021-10-27 | MDNA Life Sciences Inc. | Mitochondrial dna deletions associated with endometriosis |
| CN117384269B (zh) * | 2023-09-21 | 2024-06-18 | 南方医科大学南方医院 | 短肽mfrlp及其在制备动脉重塑相关疾病药物中的应用 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL154598B (nl) * | 1970-11-10 | 1977-09-15 | Organon Nv | Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking. |
| US3817837A (en) * | 1971-05-14 | 1974-06-18 | Syva Corp | Enzyme amplification assay |
| US3939350A (en) * | 1974-04-29 | 1976-02-17 | Board Of Trustees Of The Leland Stanford Junior University | Fluorescent immunoassay employing total reflection for activation |
| US3996345A (en) * | 1974-08-12 | 1976-12-07 | Syva Company | Fluorescence quenching with immunological pairs in immunoassays |
| US4277437A (en) * | 1978-04-05 | 1981-07-07 | Syva Company | Kit for carrying out chemically induced fluorescence immunoassay |
| US4275149A (en) * | 1978-11-24 | 1981-06-23 | Syva Company | Macromolecular environment control in specific receptor assays |
| US4366241A (en) * | 1980-08-07 | 1982-12-28 | Syva Company | Concentrating zone method in heterogeneous immunoassays |
| US5807522A (en) * | 1994-06-17 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for fabricating microarrays of biological samples |
| US6605433B1 (en) * | 1998-08-20 | 2003-08-12 | The Johns Hopkins University | Mitochondrial dosimeter |
| US6203990B1 (en) * | 1998-11-06 | 2001-03-20 | Mitokor | Method and system for pattern analysis, such as for analyzing oligonucleotide primer extension assay products |
| US6933120B2 (en) * | 2000-06-20 | 2005-08-23 | Michael D. Seidman | Method of determining biological/molecular age |
| US20050026167A1 (en) * | 2001-06-11 | 2005-02-03 | Mark Birch-Machin | Complete mitochondrial genome sequences as a diagnostic tool for the health sciences |
| US20030162174A1 (en) * | 2001-06-11 | 2003-08-28 | Sutherland John W. | Detecting nucleic acid deletion sequences |
| WO2002101086A2 (en) * | 2001-06-11 | 2002-12-19 | 1304854 Ontario Ltd. | Complete mitochondrial genome sequences as a diagnostic tool for the health sciences |
| GB2380194B (en) * | 2001-10-01 | 2005-06-22 | Roger Michael Marchbanks | A mitochondrial mutation associated with schizophrenia and increased oxidative stress |
| US20060051796A1 (en) * | 2004-09-09 | 2006-03-09 | Inga Boell | Real time PCR with the addition of pyrophosphatase |
| WO2006111029A1 (en) * | 2005-04-18 | 2006-10-26 | Genesis Genomics Inc. | Mitochondrial mutations and rearrangements as a diagnostic tool for the detection of sun exposure, prostate cancer and other cancers |
| US20070134678A1 (en) * | 2005-12-12 | 2007-06-14 | Rees Dianne M | Comparative genome hybridization of organelle genomes |
| AU2007359381B2 (en) | 2007-09-26 | 2015-06-18 | Mitomics Inc. | 3.4 kb mitochondrial DNA deletion for use in the detection of cancer |
| EP2274426B1 (en) * | 2008-03-28 | 2016-11-16 | MDNA Life Sciences Inc. | Aberrant mitochondrial dna, associated fusion transcripts and hybridization probes therefor |
| RU2011137486A (ru) | 2009-03-27 | 2013-05-10 | Митомикс Инк. | Аберрантная митохондриальная днк, ассоциированные с ней слитые транскрипты, продукты трансляции и гибрадизационные зонды |
| US20140024025A1 (en) * | 2010-03-01 | 2014-01-23 | Andrew Harbottle | Uv associated mtdna fusion transcripts and methods and uses thereof |
-
2009
- 2009-03-27 EP EP09725638.2A patent/EP2274426B1/en not_active Not-in-force
- 2009-03-27 KR KR1020107024109A patent/KR101693387B1/ko not_active Expired - Fee Related
- 2009-03-27 WO PCT/CA2009/000351 patent/WO2009117811A1/en not_active Ceased
- 2009-03-27 CA CA3044262A patent/CA3044262C/en active Active
- 2009-03-27 US US12/935,181 patent/US20110172113A1/en not_active Abandoned
- 2009-03-27 SG SG2013050448A patent/SG192453A1/en unknown
- 2009-03-27 CN CN200980114773.XA patent/CN102016039B/zh not_active Expired - Fee Related
- 2009-03-27 NZ NZ602175A patent/NZ602175A/en not_active IP Right Cessation
- 2009-03-27 AU AU2009227935A patent/AU2009227935B2/en not_active Ceased
- 2009-03-27 CA CA2719718A patent/CA2719718C/en not_active Expired - Fee Related
- 2009-03-27 CN CN201710183734.1A patent/CN107011428B/zh active Active
- 2009-03-27 JP JP2011501069A patent/JP5938690B2/ja not_active Expired - Fee Related
- 2009-03-27 NZ NZ588658A patent/NZ588658A/xx not_active IP Right Cessation
- 2009-03-27 KR KR1020167036800A patent/KR101819852B1/ko not_active Expired - Fee Related
-
2010
- 2010-03-29 CN CN201080014122.6A patent/CN102388140B/zh not_active Expired - Fee Related
- 2010-03-29 SG SG10201400985RA patent/SG10201400985RA/en unknown
- 2010-03-29 US US13/260,497 patent/US8715960B2/en not_active Expired - Fee Related
- 2010-03-29 SG SG2011068467A patent/SG174514A1/en unknown
-
2015
- 2015-02-20 US US14/627,755 patent/US10266899B2/en active Active
-
2019
- 2019-04-17 US US16/386,381 patent/US20190382846A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20130059299A1 (en) | 2013-03-07 |
| AU2009227935A1 (en) | 2009-10-01 |
| US20170152567A1 (en) | 2017-06-01 |
| KR20170004033A (ko) | 2017-01-10 |
| CA3044262A1 (en) | 2009-10-01 |
| CA3044262C (en) | 2023-02-28 |
| CA2719718C (en) | 2019-07-02 |
| SG192453A1 (en) | 2013-08-30 |
| SG10201400985RA (en) | 2014-05-29 |
| US10266899B2 (en) | 2019-04-23 |
| EP2274426B1 (en) | 2016-11-16 |
| WO2009117811A1 (en) | 2009-10-01 |
| CN102016039B (zh) | 2017-06-09 |
| CN107011428B (zh) | 2022-02-25 |
| NZ588658A (en) | 2012-10-26 |
| JP5938690B2 (ja) | 2016-06-22 |
| CA2719718A1 (en) | 2009-10-01 |
| CN102388140A (zh) | 2012-03-21 |
| US20110172113A1 (en) | 2011-07-14 |
| CN102388140B (zh) | 2015-07-08 |
| KR101693387B1 (ko) | 2017-01-05 |
| AU2009227935B2 (en) | 2015-07-09 |
| JP2011515091A (ja) | 2011-05-19 |
| EP2274426A4 (en) | 2011-11-16 |
| CN107011428A (zh) | 2017-08-04 |
| CN102016039A (zh) | 2011-04-13 |
| SG174514A1 (en) | 2011-10-28 |
| EP2274426A1 (en) | 2011-01-19 |
| KR101819852B1 (ko) | 2018-02-28 |
| KR20110004860A (ko) | 2011-01-14 |
| US20190382846A1 (en) | 2019-12-19 |
| US8715960B2 (en) | 2014-05-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PSEA | Patent sealed | ||
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 3 YEARS UNTIL 27 MAR 2016 BY BALDWINS INTELLECTUAL PROPERTY Effective date: 20141016 |
|
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 27 MAR 2017 BY IN-LEGAL LIMITED Effective date: 20160921 |
|
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 27 MAR 2018 BY COMPUTER PACKAGES INC Effective date: 20170801 |
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| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 27 MAR 2019 BY COMPUTER PACKAGES INC Effective date: 20180731 |
|
| ASS | Change of ownership |
Owner name: MDNA LIFE SCIENCES INC., 1209 ORANGE STREET, C, US Effective date: 20181218 |
|
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 27 MAR 2020 BY COMPUTER PACKAGES INC Effective date: 20190718 |
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| LAPS | Patent lapsed |