NZ598064A - Benzazepine derivatives useful as vasopressin antagonists - Google Patents
Benzazepine derivatives useful as vasopressin antagonistsInfo
- Publication number
- NZ598064A NZ598064A NZ598064A NZ59806408A NZ598064A NZ 598064 A NZ598064 A NZ 598064A NZ 598064 A NZ598064 A NZ 598064A NZ 59806408 A NZ59806408 A NZ 59806408A NZ 598064 A NZ598064 A NZ 598064A
- Authority
- NZ
- New Zealand
- Prior art keywords
- compound
- formula
- disclosed
- methyl
- derivatives useful
- Prior art date
Links
- 229940116211 Vasopressin antagonist Drugs 0.000 title 1
- 150000008038 benzoazepines Chemical class 0.000 title 1
- 239000003038 vasopressin antagonist Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 206010030113 Oedema Diseases 0.000 abstract 2
- 208000030761 polycystic kidney disease Diseases 0.000 abstract 2
- -1 2-methyl-benzoylamino Chemical group 0.000 abstract 1
- 206010065929 Cardiovascular insufficiency Diseases 0.000 abstract 1
- 206010019280 Heart failures Diseases 0.000 abstract 1
- 206010020772 Hypertension Diseases 0.000 abstract 1
- 208000019025 Hypokalemia Diseases 0.000 abstract 1
- 206010021036 Hyponatraemia Diseases 0.000 abstract 1
- 206010053198 Inappropriate antidiuretic hormone secretion Diseases 0.000 abstract 1
- GXBMIBRIOWHPDT-UHFFFAOYSA-N Vasopressin Natural products N1C(=O)C(CC=2C=C(O)C=CC=2)NC(=O)C(N)CSSCC(C(=O)N2C(CCC2)C(=O)NC(CCCN=C(N)N)C(=O)NCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(CCC(N)=O)NC(=O)C1CC1=CC=CC=C1 GXBMIBRIOWHPDT-UHFFFAOYSA-N 0.000 abstract 1
- 102000002852 Vasopressins Human genes 0.000 abstract 1
- 108010004977 Vasopressins Proteins 0.000 abstract 1
- 230000003187 abdominal effect Effects 0.000 abstract 1
- KBZOIRJILGZLEJ-LGYYRGKSSA-N argipressin Chemical compound C([C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CSSC[C@@H](C(N[C@@H](CC=2C=CC(O)=CC=2)C(=O)N1)=O)N)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(N)=O)C1=CC=CC=C1 KBZOIRJILGZLEJ-LGYYRGKSSA-N 0.000 abstract 1
- 208000019425 cirrhosis of liver Diseases 0.000 abstract 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 201000008284 inappropriate ADH syndrome Diseases 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 208000024896 potassium deficiency disease Diseases 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 230000008085 renal dysfunction Effects 0.000 abstract 1
- 230000028327 secretion Effects 0.000 abstract 1
- 208000011580 syndromic disease Diseases 0.000 abstract 1
- 229960003726 vasopressin Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/16—Benzazepines; Hydrogenated benzazepines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/5532—Seven-(or more) membered rings
- C07F9/5535—Seven-(or more) membered rings condensed with carbocyclic rings or ring systems
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2007167207 | 2007-06-26 | ||
| NZ581723A NZ581723A (en) | 2007-06-26 | 2008-06-26 | Benzazepine derivatives useful as vasopressin antagonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ598064A true NZ598064A (en) | 2013-04-26 |
Family
ID=39773045
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ598064A NZ598064A (en) | 2007-06-26 | 2008-06-26 | Benzazepine derivatives useful as vasopressin antagonists |
| NZ598067A NZ598067A (en) | 2007-06-26 | 2008-06-26 | Benzazepine derivatives useful as vasopressin antagonists |
| NZ581723A NZ581723A (en) | 2007-06-26 | 2008-06-26 | Benzazepine derivatives useful as vasopressin antagonists |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ598067A NZ598067A (en) | 2007-06-26 | 2008-06-26 | Benzazepine derivatives useful as vasopressin antagonists |
| NZ581723A NZ581723A (en) | 2007-06-26 | 2008-06-26 | Benzazepine derivatives useful as vasopressin antagonists |
Country Status (27)
| Country | Link |
|---|---|
| US (3) | US8669229B2 (enExample) |
| EP (3) | EP2374798B1 (enExample) |
| JP (3) | JP5653043B2 (enExample) |
| KR (1) | KR101487201B1 (enExample) |
| CN (3) | CN101687805A (enExample) |
| AR (1) | AR067176A1 (enExample) |
| AT (1) | ATE545633T1 (enExample) |
| AU (1) | AU2008269918B2 (enExample) |
| BR (1) | BRPI0813768A2 (enExample) |
| CA (1) | CA2690335A1 (enExample) |
| CO (1) | CO6160295A2 (enExample) |
| CY (3) | CY1113519T1 (enExample) |
| DK (3) | DK2374798T3 (enExample) |
| ES (3) | ES2380085T3 (enExample) |
| HR (3) | HRP20120310T1 (enExample) |
| IL (1) | IL202561A0 (enExample) |
| MY (3) | MY148312A (enExample) |
| NZ (3) | NZ598064A (enExample) |
| PH (2) | PH12012501363A1 (enExample) |
| PL (3) | PL2374798T3 (enExample) |
| PT (3) | PT2374797E (enExample) |
| RU (1) | RU2471784C2 (enExample) |
| SG (2) | SG182230A1 (enExample) |
| SI (3) | SI2374797T1 (enExample) |
| TW (1) | TWI459947B (enExample) |
| UA (1) | UA98966C2 (enExample) |
| WO (1) | WO2009001968A1 (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI459947B (zh) * | 2007-06-26 | 2014-11-11 | Otsuka Pharma Co Ltd | 苯并氮呯化合物及藥學製劑 |
| JP5656399B2 (ja) * | 2008-12-26 | 2015-01-21 | 大塚製薬株式会社 | 医薬及び医薬製剤 |
| CN102030709B (zh) * | 2009-09-25 | 2013-10-16 | 江苏豪森医药集团有限公司 | 用作加压素受体拮抗剂的苯并氮杂卓类化合物 |
| JP5717645B2 (ja) * | 2009-10-26 | 2015-05-13 | 大塚製薬株式会社 | ベンズアゼピン化合物 |
| GB201105537D0 (en) | 2011-03-31 | 2011-05-18 | Vantia Ltd | New process |
| CN102260213B (zh) * | 2011-05-31 | 2013-05-15 | 重庆福安药业(集团)股份有限公司 | 一种托伐普坦的制备方法 |
| TWI704919B (zh) | 2012-05-31 | 2020-09-21 | 日商大塚製藥股份有限公司 | 用於預防及/或治療多囊性腎臟病之藥物 |
| EP2941242B1 (en) * | 2012-12-28 | 2017-02-01 | Otsuka Pharmaceutical Co., Ltd. | Injectable depot formulation comprising optically active tolvaptan and process of producing the same |
| US9505737B2 (en) | 2013-01-11 | 2016-11-29 | Corsair Pharma, Inc. | Treprostinil derivative compounds and methods of using same |
| TWI660748B (zh) * | 2013-03-01 | 2019-06-01 | 日商大塚製藥股份有限公司 | 用於口服投藥之包含非晶型托伐普坦（Ｔｏｌｖａｐｔａｎ）的懸浮液 |
| TW201605488A (zh) | 2013-10-15 | 2016-02-16 | 大塚製藥股份有限公司 | 用以預防及／或治療多囊腎病之藥物 |
| US11911369B2 (en) * | 2015-03-03 | 2024-02-27 | Biohaven Therapeutics Ltd. | Prodrugs of riluzole and their method of use |
| WO2019003433A1 (ja) * | 2017-06-30 | 2019-01-03 | 大塚製薬株式会社 | ベンゾアゼピン誘導体 |
| CN107540672A (zh) * | 2017-10-10 | 2018-01-05 | 牡丹江医学院 | 一种治疗肝硬化的药物及其合成方法 |
| HU231206B1 (hu) | 2017-12-15 | 2021-10-28 | Richter Gedeon Nyrt. | Triazolobenzazepinek |
| TW201938171A (zh) | 2017-12-15 | 2019-10-01 | 匈牙利商羅特格登公司 | 作為血管升壓素Ｖ１ａ受體拮抗劑之三環化合物 |
| JP2020011957A (ja) * | 2019-07-22 | 2020-01-23 | コルセア ファーマ インコーポレイテッド | トレプロスチニル誘導体化合物およびその使用方法 |
| CN112851583B (zh) * | 2021-01-19 | 2023-09-08 | 徐州医科大学 | 新型苯并氮杂䓬类化合物、组合物及其用途 |
| KR20230143165A (ko) * | 2021-02-10 | 2023-10-11 | 상하이 센후이 메디슨 컴퍼니 리미티드 | 벤즈아제핀 화합물, 이의 제조 방법 및 이의 약학적 용도 |
| CN113112528A (zh) * | 2021-04-26 | 2021-07-13 | 中南财经政法大学 | 异常行为监控方法、装置、设备及存储介质 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5045478A (en) * | 1986-03-03 | 1991-09-03 | Becton Dickinson And Company | Vesicles and use thereof in an assay |
| US5258510A (en) * | 1989-10-20 | 1993-11-02 | Otsuka Pharma Co Ltd | Benzoheterocyclic compounds |
| EP0602209A1 (en) | 1992-07-02 | 1994-06-22 | Otsuka Pharmaceutical Co., Ltd. | Oxytocin antagonist |
| TW270927B (enExample) * | 1992-10-16 | 1996-02-21 | Otsuka Pharma Co Ltd | |
| GB9726695D0 (en) | 1997-12-17 | 1998-02-18 | Smithkline Beecham Plc | Novel compounds |
| JP4210355B2 (ja) | 1997-07-03 | 2009-01-14 | 大塚製薬株式会社 | 固形製剤組成物 |
| EA004436B1 (ru) * | 1998-09-29 | 2004-04-29 | Уайт Холдингз Корпорейшн | Замещенные 3-цианохинолины в качестве ингибиторов протеинтирозинкиназ |
| DE60102815D1 (de) | 2000-05-15 | 2004-05-19 | Paratek Pharm Innc | 7-substituierte kondensierte ring-tetrazyclin- verbindungen |
| BRPI0516922A (pt) * | 2004-11-02 | 2008-09-23 | New River Pharmaceuticals Inc | composto de ribavirina, método para fazer um composto de ribavirina, método para usar um composto de ribavirina e composição farmacêutica |
| CA2633929A1 (en) * | 2005-12-27 | 2007-07-05 | Otsuka Pharmaceutical Co., Ltd. | Water-soluble benzoazepine compound and its pharmaceutical composition |
| TWI459947B (zh) * | 2007-06-26 | 2014-11-11 | Otsuka Pharma Co Ltd | 苯并氮呯化合物及藥學製劑 |
-
2008
- 2008-06-24 TW TW097123513A patent/TWI459947B/zh active
- 2008-06-26 UA UAA201000653A patent/UA98966C2/ru unknown
- 2008-06-26 SG SG2012047056A patent/SG182230A1/en unknown
- 2008-06-26 AR ARP080102749A patent/AR067176A1/es unknown
- 2008-06-26 JP JP2009553349A patent/JP5653043B2/ja not_active Expired - Fee Related
- 2008-06-26 SI SI200831177T patent/SI2374797T1/sl unknown
- 2008-06-26 EP EP11172829.1A patent/EP2374798B1/en not_active Not-in-force
- 2008-06-26 PT PT111728283T patent/PT2374797E/pt unknown
- 2008-06-26 EP EP08765871A patent/EP2170831B1/en not_active Not-in-force
- 2008-06-26 MY MYPI20095341A patent/MY148312A/en unknown
- 2008-06-26 CA CA2690335A patent/CA2690335A1/en not_active Abandoned
- 2008-06-26 DK DK11172829.1T patent/DK2374798T3/da active
- 2008-06-26 PL PL11172829T patent/PL2374798T3/pl unknown
- 2008-06-26 MY MYPI20124513 patent/MY152805A/en unknown
- 2008-06-26 NZ NZ598064A patent/NZ598064A/xx not_active IP Right Cessation
- 2008-06-26 DK DK08765871.2T patent/DK2170831T3/da active
- 2008-06-26 PT PT08765871T patent/PT2170831E/pt unknown
- 2008-06-26 US US12/666,751 patent/US8669229B2/en not_active Expired - Fee Related
- 2008-06-26 MY MYPI20124514 patent/MY150941A/en unknown
- 2008-06-26 WO PCT/JP2008/062033 patent/WO2009001968A1/en not_active Ceased
- 2008-06-26 PH PH1/2012/501363A patent/PH12012501363A1/en unknown
- 2008-06-26 CN CN200880022253A patent/CN101687805A/zh active Pending
- 2008-06-26 AT AT08765871T patent/ATE545633T1/de active
- 2008-06-26 ES ES08765871T patent/ES2380085T3/es active Active
- 2008-06-26 SI SI200831051T patent/SI2374798T1/sl unknown
- 2008-06-26 CN CN2013101949565A patent/CN103342680A/zh active Pending
- 2008-06-26 DK DK11172828.3T patent/DK2374797T3/da active
- 2008-06-26 PL PL08765871T patent/PL2170831T3/pl unknown
- 2008-06-26 ES ES11172828.3T patent/ES2460018T3/es active Active
- 2008-06-26 CN CN2013101948844A patent/CN103342679A/zh active Pending
- 2008-06-26 KR KR20107001719A patent/KR101487201B1/ko not_active Expired - Fee Related
- 2008-06-26 RU RU2010102229/04A patent/RU2471784C2/ru not_active IP Right Cessation
- 2008-06-26 NZ NZ598067A patent/NZ598067A/xx not_active IP Right Cessation
- 2008-06-26 HR HRP20120310AT patent/HRP20120310T1/hr unknown
- 2008-06-26 EP EP11172828.3A patent/EP2374797B1/en not_active Not-in-force
- 2008-06-26 PH PH1/2012/501362A patent/PH12012501362A1/en unknown
- 2008-06-26 SI SI200830557T patent/SI2170831T1/sl unknown
- 2008-06-26 SG SG2012047064A patent/SG182231A1/en unknown
- 2008-06-26 AU AU2008269918A patent/AU2008269918B2/en not_active Ceased
- 2008-06-26 NZ NZ581723A patent/NZ581723A/en not_active IP Right Cessation
- 2008-06-26 BR BRPI0813768-4A2A patent/BRPI0813768A2/pt not_active IP Right Cessation
- 2008-06-26 ES ES11172829T patent/ES2431515T3/es active Active
- 2008-06-26 PT PT111728291T patent/PT2374798E/pt unknown
- 2008-06-26 PL PL11172828T patent/PL2374797T3/pl unknown
-
2009
- 2009-12-07 IL IL202561A patent/IL202561A0/en unknown
-
2010
- 2010-01-26 CO CO10007691A patent/CO6160295A2/es unknown
-
2012
- 2012-05-04 CY CY20121100415T patent/CY1113519T1/el unknown
-
2013
- 2013-09-24 US US14/034,943 patent/US8785386B2/en not_active Expired - Fee Related
- 2013-09-24 US US14/034,979 patent/US9073868B2/en not_active Expired - Fee Related
- 2013-10-10 CY CY20131100894T patent/CY1114491T1/el unknown
- 2013-11-18 HR HRP20131095AT patent/HRP20131095T1/hr unknown
-
2014
- 2014-05-30 HR HRP20140501AT patent/HRP20140501T1/hr unknown
- 2014-06-11 CY CY20141100426T patent/CY1115226T1/el unknown
- 2014-06-25 JP JP2014130326A patent/JP5689195B2/ja not_active Expired - Fee Related
- 2014-06-25 JP JP2014130327A patent/JP5893085B2/ja not_active Expired - Fee Related
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