BRPI0516922A - composto de ribavirina, método para fazer um composto de ribavirina, método para usar um composto de ribavirina e composição farmacêutica - Google Patents

composto de ribavirina, método para fazer um composto de ribavirina, método para usar um composto de ribavirina e composição farmacêutica

Info

Publication number
BRPI0516922A
BRPI0516922A BRPI0516922-4A BRPI0516922A BRPI0516922A BR PI0516922 A BRPI0516922 A BR PI0516922A BR PI0516922 A BRPI0516922 A BR PI0516922A BR PI0516922 A BRPI0516922 A BR PI0516922A
Authority
BR
Brazil
Prior art keywords
ribavirin
ribavirin compound
compound
making
pharmaceutical composition
Prior art date
Application number
BRPI0516922-4A
Other languages
English (en)
Inventor
Travis Mickle
Sven Guenther
Original Assignee
New River Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by New River Pharmaceuticals Inc filed Critical New River Pharmaceuticals Inc
Publication of BRPI0516922A publication Critical patent/BRPI0516922A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
    • C07K9/003—Peptides being substituted by heterocyclic radicals, e.g. bleomycin, phleomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

COMPOSTO DE RIBAVIRINA, MéTODO PARA FAZER UM COMPOSTO DE RIBAVIRINA, MéTODO PARA USAR UM COMPOSTO DE RIBAVIRINA E COMPOSIçãO FARMACêUTICA. A presente invenção refere-se a sistemas de liberação de ribavirina e mais especificamente a composições que compreendem amino ácidos, como amino ácidos ou peptídeos individuais, covalentemente ligados à ribavirina e a métodos para administrar composições de ribavirina conjugada.
BRPI0516922-4A 2004-11-02 2005-11-02 composto de ribavirina, método para fazer um composto de ribavirina, método para usar um composto de ribavirina e composição farmacêutica BRPI0516922A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US62385704P 2004-11-02 2004-11-02
PCT/US2005/039621 WO2006050421A1 (en) 2004-11-02 2005-11-02 Prodrugs of ribavirin with improved hepatic delivery

Publications (1)

Publication Number Publication Date
BRPI0516922A true BRPI0516922A (pt) 2008-09-23

Family

ID=36319525

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0516922-4A BRPI0516922A (pt) 2004-11-02 2005-11-02 composto de ribavirina, método para fazer um composto de ribavirina, método para usar um composto de ribavirina e composição farmacêutica

Country Status (10)

Country Link
US (1) US20080260691A1 (pt)
EP (1) EP1812039A1 (pt)
JP (1) JP2008522959A (pt)
KR (1) KR20070085544A (pt)
CN (1) CN101374539A (pt)
AU (1) AU2005302162A1 (pt)
BR (1) BRPI0516922A (pt)
CA (1) CA2586064A1 (pt)
IL (1) IL182941A0 (pt)
WO (1) WO2006050421A1 (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1917037A2 (en) * 2005-08-15 2008-05-07 F.Hoffmann-La Roche Ag Peg-ifn alpha and ribavirin for hbv treatment
GB0614034D0 (en) * 2006-07-14 2006-08-23 Iqur Ltd Antiviral compounds
TWI459947B (zh) * 2007-06-26 2014-11-11 Otsuka Pharma Co Ltd 苯并氮呯化合物及藥學製劑
AU2009308665B2 (en) 2008-10-31 2015-10-22 The University Of Mississippi Compositions containing delta-9-THC-amino acid esters and process of preparation
JP5656399B2 (ja) * 2008-12-26 2015-01-21 大塚製薬株式会社 医薬及び医薬製剤
JP6859559B2 (ja) * 2017-03-16 2021-04-14 二村　芳弘 抗アレルギー作用を呈するフェニルペプチド誘導体
CN111320662B (zh) * 2020-02-17 2022-11-25 南京医科大学 一类n-苄基取代的二脒那秦衍生物及其药物用途

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6340696B1 (en) * 1999-03-31 2002-01-22 The Procter & Gamble Company Viral treatment

Also Published As

Publication number Publication date
IL182941A0 (en) 2007-09-20
US20080260691A1 (en) 2008-10-23
AU2005302162A1 (en) 2006-05-11
WO2006050421A1 (en) 2006-05-11
CA2586064A1 (en) 2006-05-11
EP1812039A1 (en) 2007-08-01
CN101374539A (zh) 2009-02-25
JP2008522959A (ja) 2008-07-03
KR20070085544A (ko) 2007-08-27

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Legal Events

Date Code Title Description
B25A Requested transfer of rights approved

Owner name: SHIRE LLC (US)

Free format text: TRANSFERIDO POR FUSAO DE: NEW RIVER PHARMACEUTICALS INC.

B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]