NZ593694A - Topically active steroids for use in radiation and chemotherapeutics injury - Google Patents
Topically active steroids for use in radiation and chemotherapeutics injuryInfo
- Publication number
- NZ593694A NZ593694A NZ593694A NZ59369409A NZ593694A NZ 593694 A NZ593694 A NZ 593694A NZ 593694 A NZ593694 A NZ 593694A NZ 59369409 A NZ59369409 A NZ 59369409A NZ 593694 A NZ593694 A NZ 593694A
- Authority
- NZ
- New Zealand
- Prior art keywords
- medicament
- radiation
- chemotherapeutics
- patient
- beclomethasone
- Prior art date
Links
- 230000006378 damage Effects 0.000 title abstract 3
- 230000005855 radiation Effects 0.000 title abstract 3
- 208000027418 Wounds and injury Diseases 0.000 title 1
- 208000014674 injury Diseases 0.000 title 1
- 150000003431 steroids Chemical class 0.000 title 1
- 239000003814 drug Substances 0.000 abstract 5
- 210000001035 gastrointestinal tract Anatomy 0.000 abstract 3
- KUVIULQEHSCUHY-XYWKZLDCSA-N Beclometasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(Cl)[C@@H]1[C@@H]1C[C@H](C)[C@@](C(=O)COC(=O)CC)(OC(=O)CC)[C@@]1(C)C[C@@H]2O KUVIULQEHSCUHY-XYWKZLDCSA-N 0.000 abstract 2
- 229950000210 beclometasone dipropionate Drugs 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 241000792859 Enema Species 0.000 abstract 1
- OHYGPBKGZGRQKT-XGQKBEPLSA-N [(8s,9r,10s,11s,13s,14s,16s,17r)-9-chloro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(Cl)[C@@H]1[C@@H]1C[C@H](C)[C@@](C(=O)CO)(OC(=O)CC)[C@@]1(C)C[C@@H]2O OHYGPBKGZGRQKT-XGQKBEPLSA-N 0.000 abstract 1
- 229940092705 beclomethasone Drugs 0.000 abstract 1
- 229940006003 beclomethasone 17-monopropionate Drugs 0.000 abstract 1
- 230000005779 cell damage Effects 0.000 abstract 1
- 238000002512 chemotherapy Methods 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000003013 cytotoxicity Effects 0.000 abstract 1
- 231100000135 cytotoxicity Toxicity 0.000 abstract 1
- 239000007920 enema Substances 0.000 abstract 1
- 229940095399 enema Drugs 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000000451 tissue damage Effects 0.000 abstract 1
- 231100000827 tissue damage Toxicity 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
- A61K31/355—Tocopherols, e.g. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1825—Fibroblast growth factor [FGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Marine Sciences & Fisheries (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Toxicology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12078508P | 2008-12-08 | 2008-12-08 | |
| PCT/US2009/067199 WO2010077681A1 (en) | 2008-12-08 | 2009-12-08 | Topically active steroids for use in radiation and chemotherapeutics injury |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ593694A true NZ593694A (en) | 2013-09-27 |
Family
ID=42310112
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ593694A NZ593694A (en) | 2008-12-08 | 2009-12-08 | Topically active steroids for use in radiation and chemotherapeutics injury |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US20100183749A1 (enExample) |
| EP (2) | EP2902031B1 (enExample) |
| JP (2) | JP5709266B2 (enExample) |
| KR (2) | KR20110092351A (enExample) |
| CN (2) | CN102307466A (enExample) |
| AU (1) | AU2009333538B2 (enExample) |
| CA (1) | CA2745930C (enExample) |
| DK (2) | DK2373160T3 (enExample) |
| IL (1) | IL213411A (enExample) |
| NZ (1) | NZ593694A (enExample) |
| SG (2) | SG10201704531XA (enExample) |
| WO (1) | WO2010077681A1 (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010039861A2 (en) | 2008-09-30 | 2010-04-08 | The Regents Of The University Of Michigan | Dendrimer conjugates |
| US9017644B2 (en) | 2008-11-07 | 2015-04-28 | The Regents Of The University Of Michigan | Methods of treating autoimmune disorders and/or inflammatory disorders |
| PL3441458T3 (pl) | 2009-02-03 | 2023-11-06 | Koninklijke Nederlandse Akademie Van Wetenschappen | Podłoże do hodowli nabłonkowych komórek macierzystych i organoidów zawierających wspomniane komórki macierzyste |
| US9752124B2 (en) | 2009-02-03 | 2017-09-05 | Koninklijke Nederlandse Akademie Van Wetenschappen | Culture medium for epithelial stem cells and organoids comprising the stem cells |
| EP2412800A1 (en) | 2010-07-29 | 2012-02-01 | Koninklijke Nederlandse Akademie van Wetenschappen | Liver organoid, uses thereof and culture method for obtaining them |
| US8912323B2 (en) | 2009-10-30 | 2014-12-16 | The Regents Of The University Of Michigan | Multifunctional small molecules |
| WO2012112791A1 (en) * | 2011-02-16 | 2012-08-23 | Paloma Pharmaceuticals, Inc. | Radiation countermeasure agents |
| WO2013085718A1 (en) | 2011-12-08 | 2013-06-13 | The Regents Of The University Of Michigan | Multifunctional small molecules |
| EP2854850B1 (en) * | 2012-05-25 | 2021-05-26 | Sloan Kettering Institute For Cancer Research | Compositions for treating or preventing radiation disease and gi syndrome |
| US20160074400A1 (en) * | 2012-08-06 | 2016-03-17 | University Of Southern California | Wnt modulators for the protection, mitigation and treatment of radiation injury |
| WO2014059068A1 (en) * | 2012-10-11 | 2014-04-17 | The Trustees Of The University Of Pennsylvania | Methods for the treatment and prevention of osteoporosis and bone-related disorders |
| US9827290B2 (en) | 2013-02-28 | 2017-11-28 | The Regents Of The University Of Michigan | Compositions and methods relating to induction of intestinal stem cell homeogenesis and/or regeneration |
| US9850279B2 (en) * | 2013-09-13 | 2017-12-26 | Soligenix, Inc. | Peptides and analogs for use in the treatment of oral mucositis |
| US11311598B2 (en) | 2013-09-13 | 2022-04-26 | Soligenix, Inc. | Peptides and analogs for use in the treatment of oral mucositis |
| US9439947B2 (en) | 2014-03-28 | 2016-09-13 | Albert Einstein College Of Medicine, Inc. | Therapy for radiation-induced lung injury |
| ES3035970T3 (en) * | 2014-10-02 | 2025-09-11 | Cytosorbents Corp | Use of gastrointestinally administered porous enteron sorbent polymers to prevent or treat radiation induced mucositis, esophagitis, enteritis, colitis, and gastrointestinal acute radiation syndrome |
| WO2017011457A1 (en) * | 2015-07-12 | 2017-01-19 | The University Of Tennessee Research Foundation | Compositions and methods for protecting colonic epithelial barrier function |
| WO2017119988A2 (en) * | 2015-12-10 | 2017-07-13 | Memorial Sloan Kettering Cancer Center | Radioprotection by wnt activation |
| CN107753932A (zh) * | 2016-08-22 | 2018-03-06 | 中国辐射防护研究院 | Kgf在制备治疗或预防放射性肠炎药物中的用途 |
| GB201721615D0 (en) | 2017-12-21 | 2018-02-07 | Koninklijke Nederlandse Akademie Van Wetenschappen | Immune cell organoid co-cultures |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4661509A (en) * | 1982-09-28 | 1987-04-28 | Gordon Arnold Z | Methods for treating leukopenia |
| US5252333A (en) * | 1987-04-27 | 1993-10-12 | Scotia Holdings Plc | Lithium salt-containing pharmaceutical compositions |
| US6077692A (en) * | 1995-02-14 | 2000-06-20 | Human Genome Sciences, Inc. | Keratinocyte growth factor-2 |
| US20030144202A1 (en) * | 1996-10-15 | 2003-07-31 | Amgen Inc. | Uses of keratinocyte growth factor-2 |
| WO2001024812A1 (en) * | 1999-10-06 | 2001-04-12 | N.V. Nutricia | USE OF TRANSFORMING GROWTH FACTOR β AND GROWTH FACTORS IN THE TREATMENT AND PREVENTION OF DISEASES OF THE INTESTINAL MUCOSA |
| US20020086857A1 (en) * | 2000-09-15 | 2002-07-04 | Mcdonald George B. | Method of long-term treatment of graft-versus-host disease using topical active corticosterioids |
| US7544348B2 (en) * | 2001-02-15 | 2009-06-09 | Access Pharmaceuticals, Inc. | Liquid formulations for the prevention and treatment of mucosal diseases and disorders |
| CA2441007C (en) * | 2001-03-15 | 2009-06-09 | Enteron Pharmaceuticals, Inc. | Method of treating inflammatory disorders of the gastrointestinal tract using topical active corticosteroids |
| CN101060848B (zh) * | 2004-12-30 | 2011-06-22 | 索利吉尼克斯公司 | 用二丙酸倍氯米松和泼尼松治疗移植物抗宿主病和白血病 |
| JP4839436B2 (ja) * | 2005-11-02 | 2011-12-21 | 国立大学法人徳島大学 | 消化管粘膜保護剤、カベオリン遺伝子発現促進剤及び抗ストレス剤 |
| US20070293458A1 (en) | 2006-06-16 | 2007-12-20 | Ip-6 Research Inc. | Prevention of nuclear, solar, and other radiation-induced tissue damage |
| US20080233088A1 (en) * | 2007-02-16 | 2008-09-25 | Varian Medical Systems Technologies, Inc. | Preparative regimen for engraftment, growth and differentiation of non-hematopoeitic cells in vivo after transplantation |
| DK3354276T3 (da) * | 2007-11-13 | 2020-03-30 | Meritage Pharma Inc | Sammensætninger til behandlingen af gastrointestinal inflammation |
-
2009
- 2009-12-08 DK DK09836727.9T patent/DK2373160T3/en active
- 2009-12-08 KR KR1020117015534A patent/KR20110092351A/ko not_active Ceased
- 2009-12-08 JP JP2011539796A patent/JP5709266B2/ja not_active Expired - Fee Related
- 2009-12-08 US US12/633,631 patent/US20100183749A1/en not_active Abandoned
- 2009-12-08 CN CN2009801562821A patent/CN102307466A/zh active Pending
- 2009-12-08 EP EP15158919.9A patent/EP2902031B1/en not_active Not-in-force
- 2009-12-08 WO PCT/US2009/067199 patent/WO2010077681A1/en not_active Ceased
- 2009-12-08 KR KR1020167036277A patent/KR101783577B1/ko not_active Expired - Fee Related
- 2009-12-08 CN CN201710119024.2A patent/CN106692162A/zh active Pending
- 2009-12-08 DK DK15158919.9T patent/DK2902031T3/en active
- 2009-12-08 AU AU2009333538A patent/AU2009333538B2/en not_active Ceased
- 2009-12-08 SG SG10201704531XA patent/SG10201704531XA/en unknown
- 2009-12-08 NZ NZ593694A patent/NZ593694A/xx not_active IP Right Cessation
- 2009-12-08 SG SG2011041332A patent/SG171997A1/en unknown
- 2009-12-08 CA CA2745930A patent/CA2745930C/en active Active
- 2009-12-08 EP EP09836727.9A patent/EP2373160B1/en not_active Not-in-force
-
2011
- 2011-06-06 IL IL213411A patent/IL213411A/en active IP Right Grant
-
2014
- 2014-11-25 JP JP2014237466A patent/JP5905562B2/ja not_active Expired - Fee Related
-
2017
- 2017-04-24 US US15/495,798 patent/US20170333448A1/en not_active Abandoned
-
2019
- 2019-06-21 US US16/448,526 patent/US20200155571A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP2373160A4 (en) | 2012-06-13 |
| JP5709266B2 (ja) | 2015-04-30 |
| JP2015038155A (ja) | 2015-02-26 |
| DK2373160T3 (en) | 2018-01-02 |
| IL213411A0 (en) | 2011-07-31 |
| EP2373160B1 (en) | 2017-10-25 |
| CN102307466A (zh) | 2012-01-04 |
| IL213411A (en) | 2016-12-29 |
| US20200155571A1 (en) | 2020-05-21 |
| JP5905562B2 (ja) | 2016-04-20 |
| KR101783577B1 (ko) | 2017-09-29 |
| CA2745930A1 (en) | 2010-07-08 |
| KR20170001735A (ko) | 2017-01-04 |
| SG171997A1 (en) | 2011-07-28 |
| EP2902031A1 (en) | 2015-08-05 |
| CA2745930C (en) | 2017-05-02 |
| DK2902031T3 (en) | 2019-01-14 |
| KR20110092351A (ko) | 2011-08-17 |
| US20170333448A1 (en) | 2017-11-23 |
| US20100183749A1 (en) | 2010-07-22 |
| CN106692162A (zh) | 2017-05-24 |
| EP2902031B1 (en) | 2018-10-24 |
| AU2009333538B2 (en) | 2014-09-11 |
| SG10201704531XA (en) | 2017-07-28 |
| JP2012511034A (ja) | 2012-05-17 |
| WO2010077681A1 (en) | 2010-07-08 |
| AU2009333538A1 (en) | 2011-07-14 |
| EP2373160A1 (en) | 2011-10-12 |
| HK1207582A1 (en) | 2016-02-05 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NZ593694A (en) | Topically active steroids for use in radiation and chemotherapeutics injury | |
| NZ604029A (en) | Methods of treating bladder cancer | |
| MX2020008258A (es) | Formulaciones pediátricas de niraparib y métodos de tratamiento pediátricos. | |
| WO2012079092A3 (en) | Testosterone undecanoate compositions | |
| EA201290171A1 (ru) | Вводимые перорально кортикостероидные композиции | |
| JP2012511034A5 (enExample) | ||
| WO2010033188A3 (en) | Dosages for menstrual suppression, contraception, and hormone replacement therapy, and methods of administering same | |
| MX2014004548A (es) | Metodos para tratar pacientes pediatricos usando dexmedetomidina. | |
| JP2015038155A5 (enExample) | ||
| WO2007081773A3 (en) | Treatment of fatty liver | |
| JP5897164B2 (ja) | 外用組成物 | |
| MX2009009132A (es) | Composiciones medicinales mejoradas que comprenden buprenorfina y naltrexona. | |
| WO2012117257A8 (en) | Diethylstilbestrol dosage form and use for the treatment of prostate or breast cancer | |
| EA200800663A1 (ru) | Способ и средство профилактики и лечения нарушенного дыхания во время сна | |
| MX2011000319A (es) | Uso de rifalazil para tratar trastornos colonicos. | |
| CO6220945A2 (es) | Uso de una composicion que comprende formoterol y dipropianato de beclometasona para la prevencion y/o tratamiento de una exacerbacion de asma | |
| RU2009107068A (ru) | Применение пропиленгликоля при лечении связанных с воспалением местных нарушений или заболеваний и ран | |
| Singh et al. | Iodoform: a boon in disguise | |
| CN106163280A (zh) | 小檗碱制剂及其用途 | |
| MX2009009134A (es) | Composiciones medicinales mejoradas que comprenden buprenorfina y nalmefeno. | |
| JP2013523628A5 (enExample) | ||
| Gülnahar et al. | Effect of preemptive intravenous ibuprofen on postoperative edema and trismus in third molar tooth extraction: A randomized controlled study | |
| CN104337916A (zh) | 一种手脚冰凉及脚气的中药药剂 | |
| PH12015502274B1 (en) | Lozenge for treating a sore throat, hoarseness, and associated dry cough and for treating inflammatory diseases of the oral cavity and of the pharynx | |
| JP2016520114A5 (enExample) |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ASS | Change of ownership |
Owner name: SOLIGENIX, INC., US Free format text: OLD OWNER(S): SOLIGENIX, INC.; ROBERT N BREY; GEORGE B MCDONALD; CHRISTOPHER SCHABER |
|
| S883 | Correction of error according to section 88(3) (mistake in register caused on part of patentee or applicant) |
Free format text: CORRECTION TO APPLICANT (71) CHAIN OF TITLE AND INVENTORS (72) |
|
| PSEA | Patent sealed | ||
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 3 YEARS UNTIL 08 DEC 2016 BY AJ PARK Effective date: 20140128 |
|
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 08 DEC 2017 BY COMPUTER PACKAGES INC Effective date: 20161118 |
|
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 08 DEC 2018 BY COMPUTER PACKAGES INC Effective date: 20171118 |
|
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 08 DEC 2019 BY COMPUTER PACKAGES INC Effective date: 20181120 |
|
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 08 DEC 2020 BY COMPUTER PACKAGES INC Effective date: 20191119 |
|
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 08 DEC 2021 BY COMPUTER PACKAGES INC Effective date: 20201118 |
|
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 08 DEC 2022 BY COMPUTER PACKAGES INC Effective date: 20211117 |
|
| LAPS | Patent lapsed |