NZ591919A - Oil-in-water emulsions comprising a polymeric surfactant and water-insoluble active agent for application to skin or vaginal mucosa - Google Patents
Oil-in-water emulsions comprising a polymeric surfactant and water-insoluble active agent for application to skin or vaginal mucosaInfo
- Publication number
- NZ591919A NZ591919A NZ591919A NZ59191909A NZ591919A NZ 591919 A NZ591919 A NZ 591919A NZ 591919 A NZ591919 A NZ 591919A NZ 59191909 A NZ59191909 A NZ 59191909A NZ 591919 A NZ591919 A NZ 591919A
- Authority
- NZ
- New Zealand
- Prior art keywords
- water
- drugs
- oil
- polymeric surfactant
- insoluble active
- Prior art date
Links
- 239000000839 emulsion Substances 0.000 title abstract 3
- 239000004094 surface-active agent Substances 0.000 title abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 title abstract 2
- 239000013543 active substance Substances 0.000 title 1
- 210000004877 mucosa Anatomy 0.000 title 1
- WVDDGKGOMKODPV-UHFFFAOYSA-N Benzyl alcohol Chemical compound OCC1=CC=CC=C1 WVDDGKGOMKODPV-UHFFFAOYSA-N 0.000 abstract 3
- 229940079593 drug Drugs 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 2
- LEACJMVNYZDSKR-UHFFFAOYSA-N 2-octyldodecan-1-ol Chemical compound CCCCCCCCCCC(CO)CCCCCCCC LEACJMVNYZDSKR-UHFFFAOYSA-N 0.000 abstract 1
- 206010046914 Vaginal infection Diseases 0.000 abstract 1
- 208000032159 Vaginal inflammation Diseases 0.000 abstract 1
- 201000008100 Vaginitis Diseases 0.000 abstract 1
- 150000001252 acrylic acid derivatives Chemical class 0.000 abstract 1
- 125000005250 alkyl acrylate group Chemical group 0.000 abstract 1
- 230000000843 anti-fungal effect Effects 0.000 abstract 1
- 229940124599 anti-inflammatory drug Drugs 0.000 abstract 1
- 230000000842 anti-protozoal effect Effects 0.000 abstract 1
- 229940124350 antibacterial drug Drugs 0.000 abstract 1
- 239000003904 antiprotozoal agent Substances 0.000 abstract 1
- 230000001580 bacterial effect Effects 0.000 abstract 1
- 235000019445 benzyl alcohol Nutrition 0.000 abstract 1
- 229920003086 cellulose ether Polymers 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 229920006037 cross link polymer Polymers 0.000 abstract 1
- 230000002538 fungal effect Effects 0.000 abstract 1
- 229940088597 hormone Drugs 0.000 abstract 1
- 239000005556 hormone Substances 0.000 abstract 1
- 230000002209 hydrophobic effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000003472 neutralizing effect Effects 0.000 abstract 1
- 239000007764 o/w emulsion Substances 0.000 abstract 1
- 229920001223 polyethylene glycol Polymers 0.000 abstract 1
- 229920001451 polypropylene glycol Polymers 0.000 abstract 1
- 150000005846 sugar alcohols Polymers 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/345—Nitrofurans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Reproductive Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gynecology & Obstetrics (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Dermatology (AREA)
- Dispersion Chemistry (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Urology & Nephrology (AREA)
- Pregnancy & Childbirth (AREA)
- Tropical Medicine & Parasitology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Colloid Chemistry (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP08166058A EP2174650A1 (en) | 2008-10-08 | 2008-10-08 | Modified release emulsions for application to skin or vaginal mucosa |
| PCT/EP2009/062190 WO2010040632A1 (en) | 2008-10-08 | 2009-09-21 | Modified release emulsions for application to skin or vaginal mucosa |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ591919A true NZ591919A (en) | 2012-09-28 |
Family
ID=40340663
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ591919A NZ591919A (en) | 2008-10-08 | 2009-09-21 | Oil-in-water emulsions comprising a polymeric surfactant and water-insoluble active agent for application to skin or vaginal mucosa |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US20110195944A1 (enExample) |
| EP (2) | EP2174650A1 (enExample) |
| JP (1) | JP2012505171A (enExample) |
| KR (1) | KR20110067115A (enExample) |
| CN (1) | CN102170862A (enExample) |
| AR (1) | AR073801A1 (enExample) |
| AU (1) | AU2009301275A1 (enExample) |
| BR (1) | BRPI0920565A2 (enExample) |
| CA (1) | CA2737255A1 (enExample) |
| CL (1) | CL2011000767A1 (enExample) |
| CO (1) | CO6361898A2 (enExample) |
| EA (1) | EA201170555A1 (enExample) |
| IL (1) | IL211681A0 (enExample) |
| MA (1) | MA32687B1 (enExample) |
| MX (1) | MX2011003696A (enExample) |
| NZ (1) | NZ591919A (enExample) |
| PE (1) | PE20110449A1 (enExample) |
| WO (1) | WO2010040632A1 (enExample) |
| ZA (1) | ZA201101818B (enExample) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2667852B1 (en) * | 2011-01-27 | 2016-11-09 | GlaxoSmithKline Biologicals SA | Adjuvant nanoemulsions with crystallisation inhibitors |
| KR20140024292A (ko) | 2011-04-01 | 2014-02-28 | 유니버시티 오브 플로리다 리서치 파운데이션, 인크. | 치료제의 국소 전달용 감열성, 점막부착성 또는 표피부착성, 및 침투강화성 제제 |
| DE102011076869A1 (de) * | 2011-06-01 | 2012-12-06 | Beiersdorf Ag | Emulsionszubereitungen mit verbesserten rheologischen Eigenschaften |
| US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| RS62297B1 (sr) | 2011-11-23 | 2021-09-30 | Therapeuticsmd Inc | Prirodne kombinovane hormonske supstitucione formulacije i terapije |
| CN110075310A (zh) | 2011-12-20 | 2019-08-02 | 维奥姆治疗有限公司 | 用于治疗真菌感染的局部油组合物 |
| US10806697B2 (en) | 2012-12-21 | 2020-10-20 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US20130338122A1 (en) | 2012-06-18 | 2013-12-19 | Therapeuticsmd, Inc. | Transdermal hormone replacement therapies |
| US20150196640A1 (en) | 2012-06-18 | 2015-07-16 | Therapeuticsmd, Inc. | Progesterone formulations having a desirable pk profile |
| US10806740B2 (en) | 2012-06-18 | 2020-10-20 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US10537581B2 (en) | 2012-12-21 | 2020-01-21 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US11246875B2 (en) | 2012-12-21 | 2022-02-15 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10568891B2 (en) | 2012-12-21 | 2020-02-25 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US9180091B2 (en) | 2012-12-21 | 2015-11-10 | Therapeuticsmd, Inc. | Soluble estradiol capsule for vaginal insertion |
| US10471072B2 (en) | 2012-12-21 | 2019-11-12 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| KR101862448B1 (ko) * | 2013-04-12 | 2018-05-29 | 바이옴 바이오사이언스 피브이티. 엘티디. | 항균제의 조성물과 제제, 그 공정, 및 세균 감염을 치료하는 방법 |
| WO2015138668A1 (en) * | 2014-03-12 | 2015-09-17 | Warner Chilcott Company, Llc | Low-dose estradiol cream |
| JP2017516768A (ja) | 2014-05-22 | 2017-06-22 | セラピューティックスエムディー インコーポレーテッドＴｈｅｒａｐｅｕｔｉｃｓｍｄ， Ｉｎｃ． | 天然の併用ホルモン補充療法剤及び療法 |
| US10328087B2 (en) | 2015-07-23 | 2019-06-25 | Therapeuticsmd, Inc. | Formulations for solubilizing hormones |
| US10286077B2 (en) | 2016-04-01 | 2019-05-14 | Therapeuticsmd, Inc. | Steroid hormone compositions in medium chain oils |
| US9931349B2 (en) | 2016-04-01 | 2018-04-03 | Therapeuticsmd, Inc. | Steroid hormone pharmaceutical composition |
| JP7219712B2 (ja) * | 2016-10-13 | 2023-02-08 | キャタレント・ユーケー・スウィンドン・ザイディス・リミテッド | 膣送達のための凍結乾燥医薬組成物 |
| IL271596B2 (en) * | 2017-06-22 | 2024-07-01 | Viramal Ltd | Emulsion compositions comprising danazol for use in the treatment of an endometrial disease or condition |
| EP3787656A1 (en) | 2018-05-04 | 2021-03-10 | The Procter & Gamble Company | Compositions and methods for treating vaginal dryness |
| EP3659583B1 (en) | 2018-11-30 | 2023-06-07 | Viramal Limited | A method of preparing a gelling agent, the gelling agent obtained thereby, and the use of said gelling agent |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002058689A1 (en) * | 2000-12-05 | 2002-08-01 | Childrens Hospital Los Angeles | Pharmaceutical compositions of fenretinide having increased bioavailability and methods of using the same |
| AU2003218507A1 (en) * | 2002-04-04 | 2003-10-20 | Medicis Pharmaceutical Corporation | Methods for treating rosacea with pyridones |
| US20060018937A1 (en) * | 2002-10-25 | 2006-01-26 | Foamix Ltd. | Steroid kit and foamable composition and uses thereof |
| US20060233721A1 (en) * | 2002-10-25 | 2006-10-19 | Foamix Ltd. | Foam containing unique oil globules |
| US20040087564A1 (en) * | 2002-10-31 | 2004-05-06 | Wright D. Craig | Delivery composition and method |
| AU2006339311A1 (en) * | 2005-06-07 | 2007-09-07 | Foamix Ltd. | Antibiotic kit and composition and uses thereof |
| US20070071705A1 (en) * | 2005-09-29 | 2007-03-29 | De Oliveira Monica A M | Topical anti-microbial compositions |
| US20080075745A1 (en) * | 2006-09-21 | 2008-03-27 | Glenmark Pharmaceuticals Limited | Topical pharmaceutical compositions containing ciclopirox or a pharmaceutically acceptable salt thereof |
-
2008
- 2008-10-08 EP EP08166058A patent/EP2174650A1/en not_active Withdrawn
-
2009
- 2009-09-21 BR BRPI0920565A patent/BRPI0920565A2/pt not_active IP Right Cessation
- 2009-09-21 US US12/998,331 patent/US20110195944A1/en not_active Abandoned
- 2009-09-21 CA CA2737255A patent/CA2737255A1/en not_active Abandoned
- 2009-09-21 NZ NZ591919A patent/NZ591919A/xx not_active IP Right Cessation
- 2009-09-21 CN CN2009801391796A patent/CN102170862A/zh active Pending
- 2009-09-21 KR KR1020117007601A patent/KR20110067115A/ko not_active Withdrawn
- 2009-09-21 EA EA201170555A patent/EA201170555A1/ru unknown
- 2009-09-21 MX MX2011003696A patent/MX2011003696A/es unknown
- 2009-09-21 JP JP2011530445A patent/JP2012505171A/ja not_active Withdrawn
- 2009-09-21 WO PCT/EP2009/062190 patent/WO2010040632A1/en not_active Ceased
- 2009-09-21 AU AU2009301275A patent/AU2009301275A1/en not_active Abandoned
- 2009-09-21 PE PE2011000670A patent/PE20110449A1/es not_active Application Discontinuation
- 2009-09-21 EP EP09818802A patent/EP2331065A1/en not_active Withdrawn
- 2009-10-08 AR ARP090103886A patent/AR073801A1/es unknown
-
2011
- 2011-03-09 ZA ZA2011/01818A patent/ZA201101818B/en unknown
- 2011-03-10 IL IL211681A patent/IL211681A0/en unknown
- 2011-04-01 MA MA33736A patent/MA32687B1/fr unknown
- 2011-04-06 CL CL2011000767A patent/CL2011000767A1/es unknown
- 2011-04-07 CO CO11043013A patent/CO6361898A2/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| PE20110449A1 (es) | 2011-07-07 |
| EP2331065A1 (en) | 2011-06-15 |
| CL2011000767A1 (es) | 2011-06-17 |
| MA32687B1 (fr) | 2011-10-02 |
| EA201170555A1 (ru) | 2011-12-30 |
| AU2009301275A2 (en) | 2011-04-28 |
| BRPI0920565A2 (pt) | 2015-12-29 |
| ZA201101818B (en) | 2012-05-30 |
| AR073801A1 (es) | 2010-12-01 |
| CO6361898A2 (es) | 2012-01-20 |
| MX2011003696A (es) | 2011-06-20 |
| EP2174650A1 (en) | 2010-04-14 |
| WO2010040632A1 (en) | 2010-04-15 |
| JP2012505171A (ja) | 2012-03-01 |
| IL211681A0 (en) | 2011-06-30 |
| CN102170862A (zh) | 2011-08-31 |
| KR20110067115A (ko) | 2011-06-21 |
| CA2737255A1 (en) | 2010-04-15 |
| US20110195944A1 (en) | 2011-08-11 |
| AU2009301275A1 (en) | 2010-04-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PSEA | Patent sealed | ||
| LAPS | Patent lapsed |