NZ591908A - Methods and compositions to elicit multivalent immune responses against dominant and subdominant epitopes, expressed on cancer cells and tumor stroma - Google Patents
Methods and compositions to elicit multivalent immune responses against dominant and subdominant epitopes, expressed on cancer cells and tumor stromaInfo
- Publication number
- NZ591908A NZ591908A NZ591908A NZ59190806A NZ591908A NZ 591908 A NZ591908 A NZ 591908A NZ 591908 A NZ591908 A NZ 591908A NZ 59190806 A NZ59190806 A NZ 59190806A NZ 591908 A NZ591908 A NZ 591908A
- Authority
- NZ
- New Zealand
- Prior art keywords
- expressed
- compositions
- methods
- cancer cells
- immune responses
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title 2
- 201000011510 cancer Diseases 0.000 title 1
- 230000028993 immune response Effects 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 238000006467 substitution reaction Methods 0.000 abstract 3
- 229920001184 polypeptide Polymers 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Toxicology (AREA)
- Oncology (AREA)
- Cell Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US69157905P | 2005-06-17 | 2005-06-17 |
Publications (1)
Publication Number | Publication Date |
---|---|
NZ591908A true NZ591908A (en) | 2012-09-28 |
Family
ID=37325697
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NZ591908A NZ591908A (en) | 2005-06-17 | 2006-06-16 | Methods and compositions to elicit multivalent immune responses against dominant and subdominant epitopes, expressed on cancer cells and tumor stroma |
Country Status (14)
Country | Link |
---|---|
US (2) | US7999088B2 (de) |
EP (3) | EP2385060A3 (de) |
JP (1) | JP5416968B2 (de) |
KR (1) | KR20080026181A (de) |
CN (1) | CN101198620A (de) |
AU (1) | AU2006259220C1 (de) |
BR (1) | BRPI0611794A2 (de) |
CA (1) | CA2612516C (de) |
ES (1) | ES2413079T3 (de) |
IL (1) | IL188113A (de) |
MX (1) | MX2007015933A (de) |
NZ (1) | NZ591908A (de) |
SG (1) | SG162817A1 (de) |
WO (1) | WO2006138567A2 (de) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6977074B2 (en) | 1997-07-10 | 2005-12-20 | Mannkind Corporation | Method of inducing a CTL response |
US20030215425A1 (en) * | 2001-12-07 | 2003-11-20 | Simard John J. L. | Epitope synchronization in antigen presenting cells |
US7178491B2 (en) * | 2003-06-05 | 2007-02-20 | Caterpillar Inc | Control system and method for engine valve actuator |
JP2008526764A (ja) * | 2004-12-29 | 2008-07-24 | マンカインド コーポレイション | 免疫応答の誘導におけるcd4+細胞の回避方法 |
AU2005321940B2 (en) * | 2004-12-29 | 2012-04-19 | Mannkind Corporation | Methods to trigger, maintain and manipulate immune responses by targeted administration of biological response modifiers into lymphoid organs |
AU2005321898B2 (en) * | 2004-12-29 | 2012-07-19 | Mannkind Corporation | Use of compositions comprising various tumor-associated antigens as anti-cancer vaccines |
US8084592B2 (en) * | 2005-06-17 | 2011-12-27 | Mannkind Corporation | Multivalent entrain-and-amplify immunotherapeutics for carcinoma |
EP2371850A3 (de) * | 2005-06-17 | 2012-08-01 | Mannkind Corporation | Epitopanaloge |
EP2385060A3 (de) | 2005-06-17 | 2012-02-15 | Mannkind Corporation | Verfahren und Zusammensetzungen zum Auslösen von multivalenten Immunreaktionen gegen auf Krebszellen und Tumor-Stroma exprimierte dominante und subdominante Epitope |
JP2009544610A (ja) * | 2006-07-14 | 2009-12-17 | マンカインド コーポレイション | 予防又は治療目的のためにmhcクラスi拘束エピトープに対する免疫応答を引き出し、増強し、保持する方法 |
CA2996732C (en) | 2007-03-26 | 2020-10-27 | Academisch Ziekenhuis Leiden H.O.D.N. Lumc | Prame derived peptides and immunogenic compositions comprising these |
EP2148697B1 (de) * | 2007-05-24 | 2012-10-03 | GlaxoSmithKline Biologicals S.A. | Lyophilisierte wt-1/cpg zusammensetzung |
EP2490713A2 (de) * | 2009-10-23 | 2012-08-29 | MannKind Corporation | Krebsimmuntherapie und behandlungsverfahren |
EP4285922A1 (de) * | 2011-05-26 | 2023-12-06 | Geneius Biotechnology Investments, LLC | Modulierte immundominanztherapie |
RU2554821C1 (ru) * | 2014-02-18 | 2015-06-27 | Государственное Бюджетное Образовательное Учреждение Высшего Профессионального Образования "Красноярский Государственный Медицинский Университет Имени Профессора В.Ф. Войно-Ясенецкого Министерства Здравоохранения Российской Федерации" | Способ оценки степени локальной холодовой травмы в раннем реактивном периоде |
EP3400004A1 (de) * | 2016-01-08 | 2018-11-14 | Vaccibody AS | Therapeutischer antikrebs-neoepitop-impfstoff |
WO2017118702A1 (en) * | 2016-01-08 | 2017-07-13 | Vaccibody As | Neoepitope rna cancer vaccine |
CN106367406A (zh) * | 2016-08-28 | 2017-02-01 | 苏州普罗达生物科技有限公司 | Udp糖基转移酶免疫原多肽及其用途 |
CN106581668B (zh) * | 2016-12-31 | 2020-03-24 | 广州姿生生物科技有限公司 | 一种抗原表位肽组合物及其应用 |
CN112686128B (zh) * | 2020-12-28 | 2022-10-14 | 南京览众智能科技有限公司 | 基于机器学习的教室课桌检测方法 |
TW202309071A (zh) | 2021-05-05 | 2023-03-01 | 德商英麥提克生物技術股份有限公司 | 特異性結合prame之抗原結合蛋白 |
Family Cites Families (81)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2606601A (en) | 1948-12-14 | 1952-08-12 | Knoll Associates | Chair having a back rest in the form of a shell-like body |
US5804381A (en) | 1996-10-03 | 1998-09-08 | Cornell Research Foundation | Isolated nucleic acid molecule encoding an esophageal cancer associated antigen, the antigen itself, and uses thereof |
US6417165B1 (en) | 1988-03-27 | 2002-07-09 | Ludwig Institute For Cancer Research | NY-ESO-1-peptide derivatives, and uses thereof |
US5703055A (en) | 1989-03-21 | 1997-12-30 | Wisconsin Alumni Research Foundation | Generation of antibodies through lipid mediated DNA delivery |
EP1757694A3 (de) | 1992-11-05 | 2008-02-27 | Sloan Kettering Institute For Cancer Research | Prostata-spezifisches Membranantigen |
US5747271A (en) | 1992-12-22 | 1998-05-05 | Ludwig Institute For Cancer Research | Method for identifying individuals suffering from a cellular abnormality some of whose abnormal cells present complexes of HLA-A2/tyrosinase derived peptides, and methods for treating said individuals |
US5801005A (en) | 1993-03-17 | 1998-09-01 | University Of Washington | Immune reactivity to HER-2/neu protein for diagnosis of malignancies in which the HER-2/neu oncogene is associated |
US5620886A (en) | 1993-03-18 | 1997-04-15 | Ludwig Institute For Cancer Research | Isolated nucleic acid sequence coding for a tumor rejection antigen precursor processed to at least one tumor rejection antigen presented by HLA-A2 |
US5571711A (en) | 1993-06-17 | 1996-11-05 | Ludwig Institute For Cancer Research | Isolated nucleic acid molecules coding for BAGE tumor rejection antigen precursors |
US5648226A (en) | 1993-07-22 | 1997-07-15 | Ludwig Institute For Cancer Research | Isolated peptides derived from tumor rejection antigens, and their use |
US5610013A (en) | 1993-07-22 | 1997-03-11 | Ludwig Institute For Cancer Research | Method for diagnosing a disorder by determining expression of gage tumor rejection antigen precursors |
US6013481A (en) | 1993-07-22 | 2000-01-11 | Ludwig Institute For Cancer Research | Isolated, nucleic acid molecules which code for gage tumor rejection antigen, the tumor rejection antigen, and uses thereof |
US5858689A (en) | 1993-07-22 | 1999-01-12 | Ludwig Institute For Cancer Research | Isolated peptides derived from the gage tumor rejection antigen precursor and uses thereof |
US5679647A (en) | 1993-08-26 | 1997-10-21 | The Regents Of The University Of California | Methods and devices for immunizing a host against tumor-associated antigens through administration of naked polynucleotides which encode tumor-associated antigenic peptides |
US5935818A (en) | 1995-02-24 | 1999-08-10 | Sloan-Kettering Institute For Cancer Research | Isolated nucleic acid molecule encoding alternatively spliced prostate-specific membrane antigen and uses thereof |
US6660276B1 (en) | 1994-02-16 | 2003-12-09 | The University Of Virginia Patent Foundation | Peptides recognized by melanoma-specific cytotoxic lymphocytes, and uses therefor |
US5512444A (en) | 1994-03-01 | 1996-04-30 | Ludwig Institute For Cancer Research | Method for determining bladder tumors by assaying for MAGE-1,2,3 or 4 |
US5763165A (en) | 1994-03-10 | 1998-06-09 | Ludwig Institute For Cancer Research | Method for determining lung adenocarcinomas by assaying for one or more of MAGE-1, MAGE-2 and MAGE-3 |
US5512437A (en) | 1994-03-01 | 1996-04-30 | Ludwig Institute For Cancer Research | Method for determining head and neck squamous cell carcinomas, prostate carcinomas, and bladder tumors by assaying for mage-3 |
US5874560A (en) | 1994-04-22 | 1999-02-23 | The United States Of America As Represented By The Department Of Health And Human Services | Melanoma antigens and their use in diagnostic and therapeutic methods |
US5830753A (en) | 1994-09-30 | 1998-11-03 | Ludwig Institute For Cancer Research | Isolated nucleic acid molecules coding for tumor rejection antigen precursor dage and uses thereof. |
US5837476A (en) | 1995-03-03 | 1998-11-17 | Ludwig Institute | Methods for determining disorders by assaying for a non-tyrosinase, tumor rejection antigen precursor |
US6025191A (en) | 1995-06-07 | 2000-02-15 | Ludwig Institute For Cancer Research | Isolated nucleic acid molecules which encode a melanoma specific antigen and uses thereof |
US5788963A (en) | 1995-07-31 | 1998-08-04 | Pacific Northwest Cancer Foundation | Isolation and/or preservation of dendritic cells for prostate cancer immunotherapy |
US5840839A (en) | 1996-02-09 | 1998-11-24 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Alternative open reading frame DNA of a normal gene and a novel human cancer antigen encoded therein |
US5856136A (en) | 1996-07-03 | 1999-01-05 | Incyte Pharmaceuticals, Inc. | Human stem cell antigens |
US5908778A (en) | 1996-10-03 | 1999-06-01 | Ludwig Institute For Cancer Research | Mage-10 encoding cDNA, the tumor rejection antigen precursor mage-10, antibodies specific to the molecule, and uses thereof |
US6548064B1 (en) | 1997-05-05 | 2003-04-15 | Ludwig Institute For Cancer Research | Isolated peptides consisting of amino acid sequences found in SSX or NY-ESO-1 molecules, which bind to HLA molecules |
US6287756B1 (en) | 1997-05-05 | 2001-09-11 | Ludwig Institute For Cancer Research | Methods for determining presence of cancer in a sample by determining expression of an SSX gene |
US6025470A (en) | 1997-06-23 | 2000-02-15 | Ludwig Institute For Cancer Research | Isolated nona- and decapeptides which bind to HLA molecules, and the use thereof |
DE69834494T2 (de) | 1997-07-10 | 2007-03-01 | Mannkind Corp., Valencia | Vorrichtung zur induktion einer ctl-antwort |
US6977074B2 (en) | 1997-07-10 | 2005-12-20 | Mannkind Corporation | Method of inducing a CTL response |
US6994851B1 (en) | 1997-07-10 | 2006-02-07 | Mannkind Corporation | Method of inducing a CTL response |
US5888751A (en) | 1997-07-15 | 1999-03-30 | Ludwig Institute For Cancer Research | Method for diagnosis and treating cancers, and methods for identifying pathogenic markers in a sample of normal cells |
US6746839B1 (en) | 1998-01-12 | 2004-06-08 | Interleukin Genetics, Inc. | Diagnostics and therapeutics for an obstructive airway disease |
US5985571A (en) | 1998-02-04 | 1999-11-16 | Ludwig Institute For Cancer Research | Method for determining multiple myeloma by assaying for expression of mage genes |
US6709844B1 (en) | 2000-11-16 | 2004-03-23 | Mannkind Corporation | Avoidance of undesirable replication intermediates in plasmid propagation |
US20030138808A1 (en) | 1998-02-19 | 2003-07-24 | Simard John J.L. | Expression vectors encoding epitopes of target-associated antigens |
US6200765B1 (en) | 1998-05-04 | 2001-03-13 | Pacific Northwest Cancer Foundation | Non-invasive methods to detect prostate cancer |
US20020072493A1 (en) | 1998-05-19 | 2002-06-13 | Yeda Research And Development Co. Ltd. | Activated T cells, nervous system-specific antigens and their uses |
US6140050A (en) | 1998-06-26 | 2000-10-31 | Ludwig Institute For Cancer Research | Methods for determining breast cancer and melanoma by assaying for a plurality of antigens associated therewith |
HUP0103976A3 (en) * | 1998-10-05 | 2008-04-28 | Pharmexa As | Novel methods for therapeutic vaccination |
ATE440960T1 (de) | 1999-02-05 | 2009-09-15 | Univ Melbourne | T-helferzellen-epitope |
US6342221B1 (en) | 1999-04-28 | 2002-01-29 | Board Of Regents, The University Of Texas System | Antibody conjugate compositions for selectively inhibiting VEGF |
US6720146B2 (en) * | 1999-09-10 | 2004-04-13 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of ovarian cancer |
US6605711B1 (en) | 1999-11-15 | 2003-08-12 | Ludwig Institute For Cancer Research | NY-ESO-1 peptide derivatives, and uses thereof |
EP1118860A1 (de) | 2000-01-21 | 2001-07-25 | Rijksuniversiteit te Leiden | Verfahren zur Auswahl und zur Herstellung von T-Zellen-Peptidepitopen sowie darauf basierten Impfstoffen |
CN1452634A (zh) * | 2000-02-23 | 2003-10-29 | 埃皮缪纳股份有限公司 | Hla结合肽及其用途 |
EP2248910A1 (de) | 2000-04-28 | 2010-11-10 | Mannkind Corporation | Epitope-Synchronisierung in Antigen presentierenden Zellen |
US20030215425A1 (en) * | 2001-12-07 | 2003-11-20 | Simard John J. L. | Epitope synchronization in antigen presenting cells |
US6861234B1 (en) | 2000-04-28 | 2005-03-01 | Mannkind Corporation | Method of epitope discovery |
EP2295074A1 (de) | 2001-03-07 | 2011-03-16 | Mannkind Corporation | Anti-Neovaskulatur Präparationen zur Krebsbehandlung |
US20030044813A1 (en) | 2001-03-30 | 2003-03-06 | Old Lloyd J. | Cancer-testis antigens |
WO2003008537A2 (en) | 2001-04-06 | 2003-01-30 | Mannkind Corporation | Epitope sequences |
WO2002086071A2 (en) | 2001-04-20 | 2002-10-31 | Ludwig Institute For Cancer Research | Cancer-testis antigens |
US6794501B2 (en) | 2001-05-04 | 2004-09-21 | Ludwig Institute For Cancer Research | Colon cancer antigen panel |
DE60238864D1 (de) | 2001-11-07 | 2011-02-17 | Mankind Corp | Für epitope von antigenen kodierende expressionsvektoren und verfahren zu deren konzeption |
US6706405B2 (en) | 2002-02-11 | 2004-03-16 | Analytical Services & Materials, Inc. | Composite coating for imparting particel erosion resistance |
US6715905B2 (en) | 2002-06-17 | 2004-04-06 | Birchwood Products Limited | Lighting apparatus |
WO2004005891A2 (en) | 2002-07-10 | 2004-01-15 | The Regents Of The University Of Michigan | Expression profile of lung cancer |
JP2005537800A (ja) | 2002-09-06 | 2005-12-15 | マンカインド コーポレイション | エピトープ配列 |
EP2356999A1 (de) | 2003-06-17 | 2011-08-17 | Mannkind Corporation | Zusammensetzung zur auslösung, verbesserung und erhaltung von Immunantworten gegen MHC klasse -I-beschränkte Epitope, für prophylaktische oder therapeutische zwecke |
EP2338506A3 (de) | 2003-06-17 | 2011-10-12 | Mannkind Corporation | Kombinationen von tumor-assozierten antigenen zur behandlung von verschiedenen krebstypen |
US20060159689A1 (en) | 2004-06-17 | 2006-07-20 | Chih-Sheng Chiang | Combinations of tumor-associated antigens in diagnostics for various types of cancers |
JP5166025B2 (ja) | 2004-06-17 | 2013-03-21 | マンカインド コーポレイション | エピトープアナログ |
US20060008468A1 (en) | 2004-06-17 | 2006-01-12 | Chih-Sheng Chiang | Combinations of tumor-associated antigens in diagnostics for various types of cancers |
AU2005265181A1 (en) | 2004-06-17 | 2006-01-26 | Mannkind Corporation | Improved efficacy of immunotherapy by integrating diagnostic with therapeutic methods |
JP2008526764A (ja) | 2004-12-29 | 2008-07-24 | マンカインド コーポレイション | 免疫応答の誘導におけるcd4+細胞の回避方法 |
AU2005321940B2 (en) | 2004-12-29 | 2012-04-19 | Mannkind Corporation | Methods to trigger, maintain and manipulate immune responses by targeted administration of biological response modifiers into lymphoid organs |
AU2005321904B2 (en) | 2004-12-29 | 2012-07-12 | Mannkind Corporation | Methods to elicit, enhance and sustain immune responses against MHC class I-restricted epitopes, for prophylactic or therapeutic purposes |
AU2005321898B2 (en) | 2004-12-29 | 2012-07-19 | Mannkind Corporation | Use of compositions comprising various tumor-associated antigens as anti-cancer vaccines |
EP2371850A3 (de) | 2005-06-17 | 2012-08-01 | Mannkind Corporation | Epitopanaloge |
EP2385060A3 (de) | 2005-06-17 | 2012-02-15 | Mannkind Corporation | Verfahren und Zusammensetzungen zum Auslösen von multivalenten Immunreaktionen gegen auf Krebszellen und Tumor-Stroma exprimierte dominante und subdominante Epitope |
US8084592B2 (en) | 2005-06-17 | 2011-12-27 | Mannkind Corporation | Multivalent entrain-and-amplify immunotherapeutics for carcinoma |
JP2009544610A (ja) | 2006-07-14 | 2009-12-17 | マンカインド コーポレイション | 予防又は治療目的のためにmhcクラスi拘束エピトープに対する免疫応答を引き出し、増強し、保持する方法 |
EP2129389B1 (de) | 2007-02-15 | 2014-10-08 | MannKind Corporation | Verfahren zur verstärkung der t-zell-antwort |
EP2152890A1 (de) | 2007-05-23 | 2010-02-17 | MannKind Corporation | Multicistronische vektoren und verfahren zu deren konstruktion |
KR101718768B1 (ko) | 2009-12-21 | 2017-03-22 | 삼성전자주식회사 | 휴대용 단말기에서 전력 소모를 줄이기 위한 장치 및 방법 |
US9469902B2 (en) | 2014-02-18 | 2016-10-18 | Lam Research Corporation | Electroless deposition of continuous platinum layer |
US9814289B2 (en) | 2015-04-08 | 2017-11-14 | Otter Products, Llc | Protective folio case for an electronic device |
EP3636238B1 (de) | 2018-10-12 | 2021-04-28 | Liko Research & Development AB | Tore mit übergangsrampen für deckenhubschienen |
-
2006
- 2006-06-16 EP EP11162844A patent/EP2385060A3/de not_active Withdrawn
- 2006-06-16 SG SG201004451-9A patent/SG162817A1/en unknown
- 2006-06-16 KR KR1020087001199A patent/KR20080026181A/ko not_active Application Discontinuation
- 2006-06-16 AU AU2006259220A patent/AU2006259220C1/en not_active Ceased
- 2006-06-16 EP EP06773349A patent/EP1896494B1/de not_active Not-in-force
- 2006-06-16 US US11/454,616 patent/US7999088B2/en not_active Expired - Fee Related
- 2006-06-16 JP JP2008517146A patent/JP5416968B2/ja not_active Expired - Fee Related
- 2006-06-16 NZ NZ591908A patent/NZ591908A/xx not_active IP Right Cessation
- 2006-06-16 CN CNA2006800216014A patent/CN101198620A/zh active Pending
- 2006-06-16 MX MX2007015933A patent/MX2007015933A/es active IP Right Grant
- 2006-06-16 EP EP11162841A patent/EP2385059A3/de not_active Withdrawn
- 2006-06-16 BR BRPI0611794-5A patent/BRPI0611794A2/pt not_active IP Right Cessation
- 2006-06-16 CA CA2612516A patent/CA2612516C/en not_active Expired - Fee Related
- 2006-06-16 WO PCT/US2006/023498 patent/WO2006138567A2/en active Application Filing
- 2006-06-16 ES ES06773349T patent/ES2413079T3/es active Active
-
2007
- 2007-12-13 IL IL188113A patent/IL188113A/en not_active IP Right Cessation
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2011
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Also Published As
Publication number | Publication date |
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SG162817A1 (en) | 2010-07-29 |
CA2612516A1 (en) | 2006-12-28 |
EP2385059A3 (de) | 2012-02-15 |
EP1896494B1 (de) | 2013-04-03 |
WO2006138567A3 (en) | 2007-02-15 |
AU2006259220A1 (en) | 2006-12-28 |
EP2385060A2 (de) | 2011-11-09 |
CA2612516C (en) | 2015-03-24 |
WO2006138567A2 (en) | 2006-12-28 |
AU2006259220C1 (en) | 2013-05-16 |
US7999088B2 (en) | 2011-08-16 |
IL188113A0 (en) | 2008-03-20 |
KR20080026181A (ko) | 2008-03-24 |
JP2008543315A (ja) | 2008-12-04 |
EP2385060A3 (de) | 2012-02-15 |
CN101198620A (zh) | 2008-06-11 |
IL188113A (en) | 2015-03-31 |
EP2385059A2 (de) | 2011-11-09 |
US8674081B2 (en) | 2014-03-18 |
US20110269949A1 (en) | 2011-11-03 |
BRPI0611794A2 (pt) | 2010-09-28 |
US20070004662A1 (en) | 2007-01-04 |
EP1896494A2 (de) | 2008-03-12 |
ES2413079T3 (es) | 2013-07-15 |
AU2006259220B2 (en) | 2012-10-11 |
MX2007015933A (es) | 2008-04-21 |
JP5416968B2 (ja) | 2014-02-12 |
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