NZ589534A - Combination of aromatase inhibitors and progesterone antagonists in the treatment of breast cancer - Google Patents

Combination of aromatase inhibitors and progesterone antagonists in the treatment of breast cancer

Info

Publication number
NZ589534A
NZ589534A NZ589534A NZ58953409A NZ589534A NZ 589534 A NZ589534 A NZ 589534A NZ 589534 A NZ589534 A NZ 589534A NZ 58953409 A NZ58953409 A NZ 58953409A NZ 589534 A NZ589534 A NZ 589534A
Authority
NZ
New Zealand
Prior art keywords
combination
breast cancer
aromatase inhibitors
treatment
progesterone antagonists
Prior art date
Application number
NZ589534A
Other languages
English (en)
Inventor
Joseph S Podolski
Original Assignee
Repros Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40758440&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NZ589534(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Repros Therapeutics Inc filed Critical Repros Therapeutics Inc
Publication of NZ589534A publication Critical patent/NZ589534A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4196—1,2,4-Triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/5685—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone having an oxo group in position 17, e.g. androsterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NZ589534A 2008-04-28 2009-04-27 Combination of aromatase inhibitors and progesterone antagonists in the treatment of breast cancer NZ589534A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4845208P 2008-04-28 2008-04-28
PCT/US2009/041836 WO2009134723A1 (en) 2008-04-28 2009-04-27 Pregesteron antagonists such as cdb-4124 in the treatment of breast cancer

Publications (1)

Publication Number Publication Date
NZ589534A true NZ589534A (en) 2012-08-31

Family

ID=40758440

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ589534A NZ589534A (en) 2008-04-28 2009-04-27 Combination of aromatase inhibitors and progesterone antagonists in the treatment of breast cancer

Country Status (21)

Country Link
US (2) US20110053900A1 (https=)
EP (2) EP2974772A1 (https=)
JP (1) JP5576362B2 (https=)
KR (1) KR101349737B1 (https=)
CN (1) CN102099040B (https=)
AR (1) AR071419A1 (https=)
AU (1) AU2009241360B2 (https=)
BR (1) BRPI0911112A2 (https=)
CA (1) CA2722637C (https=)
CL (1) CL2009001011A1 (https=)
EA (1) EA019224B1 (https=)
IL (2) IL208845A (https=)
ME (1) ME01122B (https=)
MX (1) MX2010011273A (https=)
MY (1) MY161549A (https=)
NI (1) NI201000184A (https=)
NZ (1) NZ589534A (https=)
TW (1) TWI539953B (https=)
UA (1) UA101192C2 (https=)
WO (1) WO2009134723A1 (https=)
ZA (1) ZA201007648B (https=)

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UA113283C2 (xx) * 2010-12-23 2017-01-10 19-норстероїди і їх застосування для лікування прогестеронзалежних станів
JP6092880B2 (ja) * 2011-10-04 2017-03-08 インヴァイヴィス ファーマスーティカルズ インコーポレーテッドＩｎｖｉｖｉｓ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃ． 抗プロゲスチン感受性腫瘍を特定および治療する方法ならびに系
FR2997628B1 (fr) * 2012-11-08 2015-01-16 Hra Pharma Lab Produit de co-micronisation comprenant un modulateur selectif des recepteurs a la progesterone
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MX365513B (es) 2013-03-15 2019-06-06 Aprecia Pharmaceuticals LLC Forma de dosificacion de dispersion rapida que contiene levetiracetam.
HU230381B1 (hu) * 2014-02-17 2016-03-29 Richter Gedeon Nyrt Ipari eljárás szteroid intermedier előállítására
CN113559075A (zh) 2014-11-17 2021-10-29 康泰科思特生物制药公司 奥那司酮延长释放组合物和方法
AU2016326657B2 (en) 2015-09-25 2019-10-24 Context Biopharma, Inc. Methods of making onapristone intermediates
EP3389632A4 (en) 2015-12-15 2019-11-06 Context Biopharma Inc. AMORPHIC ONAPRISTON COMPOSITIONS AND METHOD FOR THE PRODUCTION THEREOF
MD3436461T2 (ro) 2016-03-28 2024-05-31 Incyte Corp Compuși pirolotriazină ca inhibitori TAM
WO2018102369A1 (en) 2016-11-30 2018-06-07 Arno Therapeutics, Inc. Methods for onapristone synthesis dehydration and deprotection
WO2018106914A1 (en) * 2016-12-09 2018-06-14 Repros Therapeutics Inc. Oral pharmaceutical compositions comprising an unmicronized selective progesterone receptor as active agent
SI3687996T1 (sl) 2017-09-27 2022-04-29 Incyte Corporation Soli pirolotriazinskih derivatov, ki so uporabne kot zaviralci TAM
MD3813800T2 (ro) 2018-06-29 2025-10-31 Incyte Corp Formulări de inhibitor al AXL/MER
RU2679625C1 (ru) * 2018-11-08 2019-02-12 Ильясов Шамиль Сионович ПРИМЕНЕНИЕ 3-О-СУЛЬФАМОИЛОКСИ-6-ОКСА-7β-МЕТИЛ-D-ГОМО-8α-ЭСТРА-1,3,5(10)-ТРИЕН-17а-ОНА ДЛЯ ЛЕЧЕНИЯ РАКА МОЛОЧНОЙ ЖЕЛЕЗЫ, ВКЛЮЧАЯ ТРИЖДЫ-НЕГАТИВНУЮ ФОРМУ, И СПОСОБ ЕГО ПОЛУЧЕНИЯ
EP4114401A1 (en) 2020-03-06 2023-01-11 Incyte Corporation Combination therapy comprising axl/mer and pd-1/pd-l1 inhibitors

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Also Published As

Publication number Publication date
IL208845A0 (en) 2011-01-31
TWI539953B (zh) 2016-07-01
JP2011518883A (ja) 2011-06-30
EA201071250A1 (ru) 2011-04-29
MY161549A (en) 2017-04-28
WO2009134723A1 (en) 2009-11-05
CA2722637C (en) 2015-03-10
CA2722637A1 (en) 2009-11-05
CL2009001011A1 (es) 2009-09-25
EA019224B1 (ru) 2014-02-28
MX2010011273A (es) 2010-12-21
IL208845A (en) 2016-08-31
ME01122B (me) 2013-03-20
IL247093A0 (en) 2016-09-29
AR071419A1 (es) 2010-06-16
WO2009134723A9 (en) 2010-01-21
ZA201007648B (en) 2011-07-27
KR20110003553A (ko) 2011-01-12
BRPI0911112A2 (pt) 2015-10-06
NI201000184A (es) 2011-08-10
CN102099040A (zh) 2011-06-15
US20110053900A1 (en) 2011-03-03
AU2009241360B2 (en) 2012-03-08
US20140343022A1 (en) 2014-11-20
EP2974772A1 (en) 2016-01-20
KR101349737B1 (ko) 2014-02-07
EP2293798A1 (en) 2011-03-16
TW201002330A (en) 2010-01-16
HK1155084A1 (en) 2012-05-11
CN102099040B (zh) 2013-06-19
UA101192C2 (uk) 2013-03-11
JP5576362B2 (ja) 2014-08-20
AU2009241360A1 (en) 2009-11-05

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