NZ588743A - Use of a protein kinase C (PKC) alpha inhibitor for treating inflammation of the skin - Google Patents
Use of a protein kinase C (PKC) alpha inhibitor for treating inflammation of the skinInfo
- Publication number
- NZ588743A NZ588743A NZ588743A NZ58874304A NZ588743A NZ 588743 A NZ588743 A NZ 588743A NZ 588743 A NZ588743 A NZ 588743A NZ 58874304 A NZ58874304 A NZ 58874304A NZ 588743 A NZ588743 A NZ 588743A
- Authority
- NZ
- New Zealand
- Prior art keywords
- pkc
- skin
- protein kinase
- treating inflammation
- alpha inhibitor
- Prior art date
Links
- 102000003923 Protein Kinase C Human genes 0.000 title abstract 5
- 108090000315 Protein Kinase C Proteins 0.000 title abstract 5
- 239000003112 inhibitor Substances 0.000 title abstract 4
- 201000004624 Dermatitis Diseases 0.000 title 1
- 102000001708 Protein Isoforms Human genes 0.000 abstract 2
- 108010029485 Protein Isoforms Proteins 0.000 abstract 2
- 102100024924 Protein kinase C alpha type Human genes 0.000 abstract 2
- 101710109947 Protein kinase C alpha type Proteins 0.000 abstract 2
- 239000012190 activator Substances 0.000 abstract 2
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 abstract 2
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 102000004877 Insulin Human genes 0.000 abstract 1
- 108090001061 Insulin Proteins 0.000 abstract 1
- 206010072170 Skin wound Diseases 0.000 abstract 1
- 239000003102 growth factor Substances 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 229940125396 insulin Drugs 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1858—Platelet-derived growth factor [PDGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/30—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/45—Transferases (2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/022—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from an adenovirus
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Molecular Biology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US48690603P | 2003-07-15 | 2003-07-15 | |
| US10/644,775 US20040037828A1 (en) | 2002-07-09 | 2003-08-21 | Methods and pharmaceutical compositions for healing wounds |
| NZ573737A NZ573737A (en) | 2003-07-15 | 2004-07-15 | Methods and pharmaceutical compositions for healing wounds comprising a PKC modulator |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ588743A true NZ588743A (en) | 2012-05-25 |
Family
ID=37134125
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ588743A NZ588743A (en) | 2003-07-15 | 2004-07-15 | Use of a protein kinase C (PKC) alpha inhibitor for treating inflammation of the skin |
| NZ573737A NZ573737A (en) | 2003-07-15 | 2004-07-15 | Methods and pharmaceutical compositions for healing wounds comprising a PKC modulator |
| NZ545318A NZ545318A (en) | 2003-07-15 | 2004-07-15 | Pharmaceutical compositions for healing wounds comprising insulin and PKC alpha inhibitor |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ573737A NZ573737A (en) | 2003-07-15 | 2004-07-15 | Methods and pharmaceutical compositions for healing wounds comprising a PKC modulator |
| NZ545318A NZ545318A (en) | 2003-07-15 | 2004-07-15 | Pharmaceutical compositions for healing wounds comprising insulin and PKC alpha inhibitor |
Country Status (6)
| Country | Link |
|---|---|
| JP (4) | JP4790609B2 (https=) |
| CN (2) | CN101850108A (https=) |
| IL (1) | IL173148A (https=) |
| NZ (3) | NZ588743A (https=) |
| RU (2) | RU2491952C2 (https=) |
| ZA (1) | ZA200600235B (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040037828A1 (en) * | 2002-07-09 | 2004-02-26 | Bar-Ilan University | Methods and pharmaceutical compositions for healing wounds |
| WO2005013885A2 (en) * | 2003-08-07 | 2005-02-17 | Healor Ltd. | Pharmaceutical compositions and methods for accelerating wound healing |
| CN102755649A (zh) * | 2007-07-30 | 2012-10-31 | 希尔洛有限公司 | 药物组合物及相关方法 |
| EP2944319A1 (en) * | 2010-11-08 | 2015-11-18 | Arava Bio-Tech Ltd. | Buffered ophthalmic compositions and use thereof |
| CA2842337C (en) * | 2011-07-28 | 2020-02-18 | Ian S. Zagon | Methods and compositions for treatment of epithelial wounds in diabetic subjects |
| CN103055304A (zh) * | 2013-01-19 | 2013-04-24 | 卓阳 | 一种治疗皮肤溃疡用复方温敏凝胶剂及其制备方法 |
| KR101523503B1 (ko) * | 2013-09-17 | 2015-05-29 | 강원대학교산학협력단 | 아디포넥틴으로부터 유래한 펩타이드 및 이를 포함하는 조성물 |
| CN106267163A (zh) * | 2015-06-09 | 2017-01-04 | 济南博创医药科技有限公司 | 一种治疗皮肤创伤的药物组合物及其药物制剂 |
| CN108514569A (zh) * | 2018-07-09 | 2018-09-11 | 广州中医药大学(广州中医药研究院) | 斜叶檀香提取物在制备皮肤创伤愈合药物中的应用 |
| CN112316148A (zh) * | 2019-08-01 | 2021-02-05 | 成都夸常奥普医疗科技有限公司 | 包含血浆的半流体的应用、包含该半流体和活性成分的药物组合物及其制备方法 |
| CN119801477A (zh) * | 2023-10-10 | 2025-04-11 | 中国石油化工股份有限公司 | 一种模拟地层弹性形变的实验装置及其使用方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA892928B (en) * | 1988-04-25 | 1991-01-30 | Pro Neuron Inc | Pharmaceutical compositions containing deoxyribonucleosides for wound healing |
| US5591709A (en) * | 1991-08-30 | 1997-01-07 | Life Medical Sciences, Inc. | Compositions and methods for treating wounds |
| US5948898A (en) * | 1992-03-16 | 1999-09-07 | Isis Pharmaceuticals, Inc. | Methoxyethoxy oligonucleotides for modulation of protein kinase C expression |
| US6537973B1 (en) * | 1992-03-16 | 2003-03-25 | Isis Pharmaceuticals, Inc. | Oligonucleotide inhibition of protein kinase C |
| GB9210574D0 (en) * | 1992-05-18 | 1992-07-01 | Ca Nat Research Council | Biotherapeutic cell-coated microspheres for wound/burn and prothesis implant applications |
| GB2304047A (en) * | 1995-08-09 | 1997-03-12 | Univ Manchester | Pharmaceutical compositions containing cytokines |
| DE69722176T2 (de) * | 1996-01-23 | 2004-03-18 | The Board Of Trustees Of The Leland Stanford Junior University, Palo Alto | Verfahren zur suche nach transdominanten effektorpeptiden und rna-molekülen |
| AU781547B2 (en) * | 1999-04-14 | 2005-05-26 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Compositions containing immunotoxins and agents that inhibit dendritic cell maturation for inducing immune tolerance to a graft |
| WO2002009639A2 (en) * | 2000-07-31 | 2002-02-07 | Bar Ilan University | Methods and pharmaceutical compositions for healing wounds |
| GB2369572A (en) * | 2000-11-29 | 2002-06-05 | Raft Trustees Ltd | Wound treatment composition comprising insulin |
| US20020119914A1 (en) * | 2000-12-26 | 2002-08-29 | Deguang Zhu | New uses of insulin and pancreatin |
-
2004
- 2004-07-15 NZ NZ588743A patent/NZ588743A/xx not_active IP Right Cessation
- 2004-07-15 CN CN200910217138A patent/CN101850108A/zh active Pending
- 2004-07-15 CN CN2004800265295A patent/CN1852722B/zh not_active Expired - Fee Related
- 2004-07-15 NZ NZ573737A patent/NZ573737A/en not_active IP Right Cessation
- 2004-07-15 JP JP2006520104A patent/JP4790609B2/ja not_active Expired - Fee Related
- 2004-07-15 NZ NZ545318A patent/NZ545318A/en not_active IP Right Cessation
- 2004-07-15 ZA ZA200600235A patent/ZA200600235B/xx unknown
- 2004-07-15 RU RU2010130763/15A patent/RU2491952C2/ru not_active IP Right Cessation
-
2006
- 2006-01-15 IL IL173148A patent/IL173148A/en not_active IP Right Cessation
-
2008
- 2008-09-29 RU RU2008138473/14A patent/RU2404799C2/ru not_active IP Right Cessation
-
2010
- 2010-12-22 JP JP2010285810A patent/JP2011057711A/ja active Pending
- 2010-12-22 JP JP2010285808A patent/JP2011057709A/ja not_active Ceased
- 2010-12-22 JP JP2010285809A patent/JP2011057710A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| IL173148A0 (en) | 2006-06-11 |
| JP2011057710A (ja) | 2011-03-24 |
| NZ545318A (en) | 2009-06-26 |
| RU2010130763A (ru) | 2012-01-27 |
| RU2491952C2 (ru) | 2013-09-10 |
| CN1852722A (zh) | 2006-10-25 |
| RU2008138473A (ru) | 2010-04-10 |
| JP4790609B2 (ja) | 2011-10-12 |
| CN1852722B (zh) | 2011-06-08 |
| IL173148A (en) | 2013-02-28 |
| JP2007530426A (ja) | 2007-11-01 |
| JP2011057711A (ja) | 2011-03-24 |
| ZA200600235B (en) | 2007-04-25 |
| CN101850108A (zh) | 2010-10-06 |
| NZ573737A (en) | 2011-06-30 |
| RU2404799C2 (ru) | 2010-11-27 |
| JP2011057709A (ja) | 2011-03-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PSEA | Patent sealed | ||
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 3 YEARS UNTIL 15 JUL 2014 BY AJ PARK Effective date: 20121231 Free format text: PATENT RENEWED FOR 3 YEARS UNTIL 15 JUL 2011 BY AJ PARK Effective date: 20121231 |
|
| LAPS | Patent lapsed |