NZ579048A - Methods for determining cancer resistance to histone deacetylase inhibitors - Google Patents

Methods for determining cancer resistance to histone deacetylase inhibitors

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Publication number
NZ579048A
NZ579048A NZ579048A NZ57904808A NZ579048A NZ 579048 A NZ579048 A NZ 579048A NZ 579048 A NZ579048 A NZ 579048A NZ 57904808 A NZ57904808 A NZ 57904808A NZ 579048 A NZ579048 A NZ 579048A
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NZ
New Zealand
Prior art keywords
cancer
biomarker genes
expression
expression level
tm4sf4
Prior art date
Application number
NZ579048A
Other languages
English (en)
Inventor
Joseph J Buggy
Sriram Balasubramanian
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Pharmacyclics Inc
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Publication date
Application filed by Pharmacyclics Inc filed Critical Pharmacyclics Inc
Publication of NZ579048A publication Critical patent/NZ579048A/en

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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0693—Tumour cells; Cancer cells
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    • C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
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    • C12Q2537/00—Reactions characterised by the reaction format or use of a specific feature
    • C12Q2537/10—Reactions characterised by the reaction format or use of a specific feature the purpose or use of
    • C12Q2537/143—Multiplexing, i.e. use of multiple primers or probes in a single reaction, usually for simultaneously analyse of multiple analysis
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    • C12Q2545/00—Reactions characterised by their quantitative nature
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    • C12Q2600/00—Oligonucleotides characterized by their use
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/136—Screening for pharmacological compounds
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

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  • Health & Medical Sciences (AREA)
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  • Chemical & Material Sciences (AREA)
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  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
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  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
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  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
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NZ579048A 2007-01-30 2008-01-30 Methods for determining cancer resistance to histone deacetylase inhibitors NZ579048A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US88731807P 2007-01-30 2007-01-30
US91185507P 2007-04-13 2007-04-13
PCT/US2008/052540 WO2008095050A1 (en) 2007-01-30 2008-01-30 Methods for determining cancer resistance to histone deacetylase inhibitors

Publications (1)

Publication Number Publication Date
NZ579048A true NZ579048A (en) 2012-05-25

Family

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NZ579048A NZ579048A (en) 2007-01-30 2008-01-30 Methods for determining cancer resistance to histone deacetylase inhibitors

Country Status (10)

Country Link
US (3) US7838234B2 (show.php)
EP (2) EP2993473A1 (show.php)
JP (2) JP5670055B2 (show.php)
KR (1) KR101483805B1 (show.php)
CN (1) CN101657217B (show.php)
AU (2) AU2008210421B2 (show.php)
CA (1) CA2677000A1 (show.php)
EA (2) EA017985B1 (show.php)
NZ (1) NZ579048A (show.php)
WO (1) WO2008095050A1 (show.php)

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KR20090106417A (ko) 2009-10-08
EP2107911A1 (en) 2009-10-14
US20090123374A1 (en) 2009-05-14
EP2107911A4 (en) 2010-09-22
KR101483805B1 (ko) 2015-01-16
US20110053164A1 (en) 2011-03-03
US20160160286A1 (en) 2016-06-09
JP2014221049A (ja) 2014-11-27
EP2993473A1 (en) 2016-03-09
US7838234B2 (en) 2010-11-23
JP5670055B2 (ja) 2015-02-18
EA200900927A1 (ru) 2010-04-30
CN101657217A (zh) 2010-02-24
JP2010518811A (ja) 2010-06-03
WO2008095050A1 (en) 2008-08-07
AU2014203224A1 (en) 2014-07-10
AU2008210421A1 (en) 2008-08-07
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US9128096B2 (en) 2015-09-08

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