NZ563397A - Antifungal agents comprising indolizinyl derivatives - Google Patents

Antifungal agents comprising indolizinyl derivatives

Info

Publication number
NZ563397A
NZ563397A NZ563397A NZ56339706A NZ563397A NZ 563397 A NZ563397 A NZ 563397A NZ 563397 A NZ563397 A NZ 563397A NZ 56339706 A NZ56339706 A NZ 56339706A NZ 563397 A NZ563397 A NZ 563397A
Authority
NZ
New Zealand
Prior art keywords
phenyl
oxo
indolizin
acetamide
alpha
Prior art date
Application number
NZ563397A
Other languages
English (en)
Inventor
Samantha Patricia Thomson
Rhian Teresa Davies
Nigel Mark Allanson
Alexandre Kuvshinov
Gareth Morse Davies
Philip Neil Edwards
Original Assignee
F2G Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0510190A external-priority patent/GB0510190D0/en
Priority claimed from GB0607841A external-priority patent/GB0607841D0/en
Application filed by F2G Ltd filed Critical F2G Ltd
Publication of NZ563397A publication Critical patent/NZ563397A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Dermatology (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NZ563397A 2005-05-18 2006-05-18 Antifungal agents comprising indolizinyl derivatives NZ563397A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0510190A GB0510190D0 (en) 2005-05-18 2005-05-18 Antifungal agents
GB0607841A GB0607841D0 (en) 2006-04-20 2006-04-20 Antifungal agents
PCT/GB2006/001820 WO2006123145A1 (en) 2005-05-18 2006-05-18 Antifungal agents

Publications (1)

Publication Number Publication Date
NZ563397A true NZ563397A (en) 2010-04-30

Family

ID=36763577

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ563397A NZ563397A (en) 2005-05-18 2006-05-18 Antifungal agents comprising indolizinyl derivatives

Country Status (11)

Country Link
US (1) US8486962B2 (https=)
EP (1) EP1888063B1 (https=)
JP (1) JP5172661B2 (https=)
AT (1) ATE420639T1 (https=)
AU (1) AU2006248812B2 (https=)
CA (1) CA2608977C (https=)
DE (1) DE602006004865D1 (https=)
DK (1) DK1888063T3 (https=)
ES (1) ES2321230T3 (https=)
NZ (1) NZ563397A (https=)
WO (1) WO2006123145A1 (https=)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0623209D0 (en) * 2006-11-21 2007-01-03 F2G Ltd Antifungal agents
GB0710121D0 (en) * 2007-05-25 2007-07-04 F2G Ltd Antifungal agents
DE102007037579B4 (de) 2007-08-09 2012-05-16 Emc Microcollections Gmbh Neue Benzimidazol-2-yl-alkylamine und ihre Anwendung als mikrobizide Wirkstoffe
CN101168532B (zh) * 2007-11-30 2010-06-02 中科院嘉兴中心应用化学分中心 一种n-甲基哌嗪取代苯胺的合成方法
DK2626361T3 (en) 2008-04-24 2015-01-19 F2G Ltd Pyrrol-Antimycotics
GB0809773D0 (en) * 2008-05-29 2008-07-09 F2G Ltd Antifungal combination therapy
CN103153958A (zh) 2010-07-02 2013-06-12 先正达参股股份有限公司 新颖的杀微生物的二肟醚衍生物
CN103038217A (zh) 2010-07-29 2013-04-10 先正达参股股份有限公司 新颖的杀微生物的二肟醚衍生物
BR112013006671A2 (pt) 2010-09-23 2016-06-07 Syngenta Participations Ag microbiocidas21
WO2012062844A1 (en) 2010-11-12 2012-05-18 Syngenta Participations Ag Novel microbiocides
WO2012117021A2 (en) 2011-03-03 2012-09-07 Syngenta Participations Ag Novel microbiocidal oxime ethers
UY34279A (es) 2011-08-23 2013-04-05 Syngenta Participations Ag Compuestos heterocíclicos activos como microbiocidas, intermediarios, composiciones y usos
WO2013092460A1 (en) 2011-12-20 2013-06-27 Syngenta Participations Ag Cyclic bisoxime microbicides
US20150025105A1 (en) * 2012-02-09 2015-01-22 Praveen Rao Perampalli Nekkar Indolizine derivatives
EP2641901A1 (en) 2012-03-22 2013-09-25 Syngenta Participations AG. Novel microbiocides
CN102964256B (zh) * 2012-11-28 2014-05-07 浙江海翔药业股份有限公司 一种4-氨基-n,n-二甲基苄胺的制备方法
CN104744302A (zh) * 2013-12-31 2015-07-01 上海药谷药业有限公司 一种2-(4-氨基苯基)-2-甲基丙腈化合物的制备方法
CA2982660C (en) * 2014-11-21 2023-01-24 F2G Limited 2-(1,5-dimethyl-3-phenyl-1h-pyrrol-2-yl)-n-(4-(4-(5-fluoropyrimidin-2-yl)piperazine-1-yl)phenyl)-2-oxoacetamide and derivatives thereof for use as antifungal agents
GB201609222D0 (en) 2016-05-25 2016-07-06 F2G Ltd Pharmaceutical formulation
US11819503B2 (en) 2019-04-23 2023-11-21 F2G Ltd Method of treating coccidioides infection
CN112898316A (zh) * 2019-12-03 2021-06-04 微境生物医药科技(上海)有限公司 新型吡咯化合物
CN114644634B (zh) * 2020-12-21 2023-06-20 深圳市祥根生物医药有限公司 一种吡咯衍生物及其制备方法和用途
CN114031502A (zh) * 2021-10-09 2022-02-11 南京一苇医药科技有限公司 一种对硝基苯丙酮的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9508298A (pt) 1994-07-21 1998-11-03 Shionogi & Co Inibidores de indolizina de spla2
EP1399442B1 (en) * 2001-06-06 2006-08-09 Vertex Pharmaceuticals Incorporated Cak inhibitors and uses thereof
CA2517034A1 (en) 2003-03-13 2004-09-30 Synta Pharmaceuticals Corp. Fused pyrrole compounds

Also Published As

Publication number Publication date
EP1888063A1 (en) 2008-02-20
AU2006248812A1 (en) 2006-11-23
ATE420639T1 (de) 2009-01-15
US20080161302A1 (en) 2008-07-03
US8486962B2 (en) 2013-07-16
EP1888063B1 (en) 2009-01-14
JP2008545647A (ja) 2008-12-18
ES2321230T3 (es) 2009-06-03
DE602006004865D1 (de) 2009-03-05
CA2608977C (en) 2014-09-23
CA2608977A1 (en) 2006-11-23
AU2006248812B2 (en) 2012-02-16
DK1888063T3 (da) 2009-05-11
WO2006123145A1 (en) 2006-11-23
JP5172661B2 (ja) 2013-03-27

Similar Documents

Publication Publication Date Title
CA2608977C (en) Antifungal agents
JP5372767B2 (ja) 抗真菌剤としての２−［（２−置換された）−インドリジン−３−イル］−２−オキソ−アセトアミド誘導体
KR102104125B1 (ko) 소염 화합물
CA2725445A1 (en) Antifungal combination therapy
JP2018530524A (ja) アルデヒドコンジュゲートおよびその使用
KR20040081123A (ko) 쿠마린 유도체, 이의 제조 방법 및 용도
JP7723400B2 (ja) 線維症疾患の治療及び／又は予防用インドリン誘導体
US20030171379A1 (en) Methods of treating, preventing, or inhibiting inflammation with Mactanamide compounds
KR20020090152A (ko) 우울증 또는 불안증을 위한 배합 치료
JP2007191461A (ja) ピラゾール化合物及びそれらピラゾール化合物を含んでなる糖尿病治療薬
US20030166516A1 (en) Methods of treating, preventing, or inhibiting inflammation with exumolide compounds
JPWO2006126695A1 (ja) ピラゾール化合物及びそれらピラゾール化合物を含んでなる糖尿病治療薬

Legal Events

Date Code Title Description
PSEA Patent sealed
RENW Renewal (renewal fees accepted)
RENW Renewal (renewal fees accepted)

Free format text: PATENT RENEWED FOR 3 YEARS UNTIL 18 MAY 2016 BY CPA GLOBAL

Effective date: 20130405

RENW Renewal (renewal fees accepted)

Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 18 MAY 2017 BY CPA GLOBAL

Effective date: 20160405

RENW Renewal (renewal fees accepted)

Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 18 MAY 2018 BY CPA GLOBAL

Effective date: 20170407

RENW Renewal (renewal fees accepted)

Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 18 MAY 2019 BY CPA GLOBAL

Effective date: 20180622

RENW Renewal (renewal fees accepted)

Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 18 MAY 2020 BY CPA GLOBAL

Effective date: 20190404

RENW Renewal (renewal fees accepted)

Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 18 MAY 2021 BY CPA GLOBAL

Effective date: 20200403

RENW Renewal (renewal fees accepted)

Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 18 MAY 2022 BY CPA GLOBAL

Effective date: 20210401

RENW Renewal (renewal fees accepted)

Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 18 MAY 2023 BY CPA GLOBAL

Effective date: 20220401

RENW Renewal (renewal fees accepted)

Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 18 MAY 2024 BY AMIT SINGH

Effective date: 20230513

RENW Renewal (renewal fees accepted)

Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 18 MAY 2025 BY ABHISHEK KUMAR - CPA-PTO PAYMENTS

Effective date: 20240404

LAPS Patent lapsed