NZ543319A - Compositions and methods for treating amyloidosis using sulphonate derivatives - Google Patents

Compositions and methods for treating amyloidosis using sulphonate derivatives

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Publication number
NZ543319A
NZ543319A NZ543319A NZ54331900A NZ543319A NZ 543319 A NZ543319 A NZ 543319A NZ 543319 A NZ543319 A NZ 543319A NZ 54331900 A NZ54331900 A NZ 54331900A NZ 543319 A NZ543319 A NZ 543319A
Authority
NZ
New Zealand
Prior art keywords
compound
pharmaceutically acceptable
ester
formula
acceptable salt
Prior art date
Application number
NZ543319A
Other languages
English (en)
Inventor
Heather Gordon
Walter Szarek
Donald Weaver
Xianqi Kong
Original Assignee
Neurochem Int Ltd
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Filing date
Publication date
Application filed by Neurochem Int Ltd filed Critical Neurochem Int Ltd
Publication of NZ543319A publication Critical patent/NZ543319A/en

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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
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    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
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    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
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