NZ539223A - Single copy genomic hybridization probes and method of generating same - Google Patents
Single copy genomic hybridization probes and method of generating sameInfo
- Publication number
- NZ539223A NZ539223A NZ539223A NZ53922301A NZ539223A NZ 539223 A NZ539223 A NZ 539223A NZ 539223 A NZ539223 A NZ 539223A NZ 53922301 A NZ53922301 A NZ 53922301A NZ 539223 A NZ539223 A NZ 539223A
- Authority
- NZ
- New Zealand
- Prior art keywords
- sequence
- sequences
- nucleic acid
- abnormality
- probes
- Prior art date
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- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6841—In situ hybridisation
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
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- Investigating Or Analysing Biological Materials (AREA)
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| US09/854,867 US7014997B2 (en) | 2000-05-16 | 2001-05-14 | Chromosome structural abnormality localization with single copy probes |
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| US6828097B1 (en) | 2000-05-16 | 2004-12-07 | The Childrens Mercy Hospital | Single copy genomic hybridization probes and method of generating same |
| US7081339B2 (en) * | 2002-04-12 | 2006-07-25 | Primera Biosystems, Inc. | Methods for variation detection |
| KR20050073466A (ko) * | 2002-09-30 | 2005-07-13 | 칠드런스 머시 호스피탈 | 서브텔로미어 디엔에이 프로브 및 이의 제조 방법 |
| GB0326197D0 (en) * | 2003-11-10 | 2003-12-17 | Randox Lab Ltd | Molecular marker |
| CA2566395A1 (en) * | 2004-03-26 | 2005-10-13 | The Children's Mercy Hospital | Computational selection of probes for localizing chromosome breakpoints |
| US20060223075A1 (en) * | 2005-03-29 | 2006-10-05 | Exagen Diagnostics, Inc. | Unique sequence hybridization probes (USP) |
| US8407013B2 (en) | 2005-06-07 | 2013-03-26 | Peter K. Rogan | AB initio generation of single copy genomic probes |
| US7734424B1 (en) | 2005-06-07 | 2010-06-08 | Rogan Peter K | Ab initio generation of single copy genomic probes |
| AU2006327111A1 (en) * | 2005-11-18 | 2007-06-28 | The Children's Mercy Hospital | Mitigation of Cot-1 DNA distortion in nucleic acid hybridization |
| ES2372427T3 (es) | 2006-09-01 | 2012-01-19 | Ventana Medical Systems, Inc. | Método para producir sondas de ácido nucleico. |
| EP3276349B1 (en) | 2006-11-01 | 2019-08-07 | Ventana Medical Systems, Inc. | Haptens, hapten conjugates, compositions thereof and method for their preparation and use |
| WO2008119084A1 (en) * | 2007-03-28 | 2008-10-02 | The Children's Mercy Hospital | Method for identifying and selecting low copy nucleic acid segments |
| US7682789B2 (en) | 2007-05-04 | 2010-03-23 | Ventana Medical Systems, Inc. | Method for quantifying biomolecules conjugated to a nanoparticle |
| US7985557B2 (en) | 2007-05-23 | 2011-07-26 | Ventana Medical Systems, Inc. | Polymeric carriers for immunohistochemistry and in situ hybridization |
| CA2979353C (en) | 2008-06-05 | 2020-06-30 | Ventana Medical Systems, Inc. | Compositions comprising nanomaterials and method for using such compositions for histochemical processes |
| CN103003443B (zh) | 2009-11-23 | 2016-09-21 | 拜尔作物科学股份有限公司 | 耐除草剂大豆植物及鉴定其的方法 |
| CA2781557C (en) | 2009-11-23 | 2018-01-09 | Bayer Cropscience N.V. | Elite event ee-gm3 and methods and kits for identifying such event in biological samples |
| JP5838169B2 (ja) * | 2009-12-31 | 2016-01-06 | ヴェンタナ メディカル システムズ， インク． | 一意的に特異的核酸プローブを生成するための方法 |
| WO2016077426A1 (en) * | 2014-11-11 | 2016-05-19 | Abbott Molecular Inc. | Hybridization probes and methods |
| CN114350752B (zh) | 2015-07-17 | 2025-02-25 | 布鲁克空间生物学公司 | 在横切面组织的用户定义区域中的基因表达的同时定量 |
| WO2017214417A1 (en) * | 2016-06-10 | 2017-12-14 | Takara Bio Usa, Inc. | Methods and compositions employing blocked primers |
| US20230183780A1 (en) | 2016-07-25 | 2023-06-15 | InVivo BioTech Services GmbH | Dna probes for in situ hybridization on chromosomes |
| AU2017361521B2 (en) | 2016-11-21 | 2020-08-27 | Bruker Spatial Biology, Inc. | Chemical compositions and methods of using same |
| KR102893736B1 (ko) | 2018-05-14 | 2025-11-28 | 브루커 스페이셜 바이올로지, 인크. | 화학 조성물 및 이의 사용 방법 |
| EP3940075A1 (en) * | 2020-07-17 | 2022-01-19 | Istituto Nazionale Di Genetica Molecolare-INGM | Inhibitors of line1 and uses thereof |
| CN113483931B (zh) * | 2021-07-02 | 2023-01-24 | 中国国家铁路集团有限公司 | 弓网接触力区段异常识别方法及装置 |
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| US5110920A (en) | 1982-01-22 | 1992-05-05 | Cetus Corporation | HLA typing method and DNA probes used therein |
| US5985549A (en) | 1985-10-22 | 1999-11-16 | University Of Massachusetts | Non-isotopic in-situ hybridization method for detection of nucleic acids |
| US5721098A (en) * | 1986-01-16 | 1998-02-24 | The Regents Of The University Of California | Comparative genomic hybridization |
| US5756696A (en) * | 1986-01-16 | 1998-05-26 | Regents Of The University Of California | Compositions for chromosome-specific staining |
| US5447841A (en) | 1986-01-16 | 1995-09-05 | The Regents Of The Univ. Of California | Methods for chromosome-specific staining |
| US5273881A (en) | 1990-05-07 | 1993-12-28 | Daikin Industries, Ltd. | Diagnostic applications of double D-loop formation |
| US6040140A (en) * | 1991-12-11 | 2000-03-21 | Thomas Jefferson University | Methods for screening and treating leukemias resulting from all-1 region chromosome abnormalities |
| US6121419A (en) * | 1992-06-17 | 2000-09-19 | Arch Development Corp. | Compositions and methods for detecting gene rearrangements and translocations |
| WO1994017208A1 (en) * | 1993-01-21 | 1994-08-04 | President And Fellows Of Harvard College | Methods and diagnostic kits utilizing mammalian stress promoters to determine toxicity of a compound |
| US6150160A (en) * | 1995-11-16 | 2000-11-21 | The John Hopkins University | Compositions and methods of use of mammalian retrotransposons |
| US6222029B1 (en) * | 1997-08-01 | 2001-04-24 | Genset | 5′ ESTs for secreted proteins expressed in brain |
| US6828097B1 (en) * | 2000-05-16 | 2004-12-07 | The Childrens Mercy Hospital | Single copy genomic hybridization probes and method of generating same |
| WO2002093130A2 (en) * | 2001-05-14 | 2002-11-21 | Cancer Genetics, Inc. | Methods of analyzing chromosomal translocations using fluorescence in situ hybridization (fish) |
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