JP2004523201A - シングルコピーゲノムのハイブリダイゼーションプローブおよびその作製方法 - Google Patents

シングルコピーゲノムのハイブリダイゼーションプローブおよびその作製方法 Download PDF

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JP2004523201A
JP2004523201A JP2001585298A JP2001585298A JP2004523201A JP 2004523201 A JP2004523201 A JP 2004523201A JP 2001585298 A JP2001585298 A JP 2001585298A JP 2001585298 A JP2001585298 A JP 2001585298A JP 2004523201 A JP2004523201 A JP 2004523201A
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probe
sequence
nucleic acid
hybridization
dna
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JP2001585298A
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JP2004523201A5 (enExample
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ジョーン エイチ． エム． ノール
ピーター ケイ． ローガン
パトリシア エム． カザッロ
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ザ チルドレンズ マーシー ホスピタル
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Priority claimed from US09/573,080 external-priority patent/US6828097B1/en
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Publication of JP2004523201A5 publication Critical patent/JP2004523201A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6841—In situ hybridisation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
JP2001585298A 2000-05-16 2001-05-15 シングルコピーゲノムのハイブリダイゼーションプローブおよびその作製方法 Pending JP2004523201A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/573,080 US6828097B1 (en) 2000-05-16 2000-05-16 Single copy genomic hybridization probes and method of generating same
US09/854,867 US7014997B2 (en) 2000-05-16 2001-05-14 Chromosome structural abnormality localization with single copy probes
PCT/US2001/015674 WO2001088089A2 (en) 2000-05-16 2001-05-15 Single copy genomic hybridization probes and method of generating same

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JP2004523201A true JP2004523201A (ja) 2004-08-05
JP2004523201A5 JP2004523201A5 (enExample) 2011-09-01

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JP2001585298A Pending JP2004523201A (ja) 2000-05-16 2001-05-15 シングルコピーゲノムのハイブリダイゼーションプローブおよびその作製方法

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US (2) US20080085509A1 (enExample)
EP (1) EP1285093A4 (enExample)
JP (1) JP2004523201A (enExample)
AU (2) AU2001264610B2 (enExample)
CA (1) CA2409752A1 (enExample)
IL (1) IL152727A0 (enExample)
NZ (2) NZ539223A (enExample)
WO (1) WO2001088089A2 (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008534011A (ja) * 2005-03-29 2008-08-28 エグザジェン ダイアグノスティクス インコーポレイテッド ユニーク配列ハイブリダイゼーションプローブ（ｕｓｐ）
JP2010522571A (ja) * 2007-03-28 2010-07-08 ザ チルドレンズ マーシー ホスピタル 少コピー数の核酸セグメントを同定および選択する方法
JP2017533733A (ja) * 2014-11-11 2017-11-16 アボツト・モレキユラー・インコーポレイテツド ハイブリダイゼーションプローブおよび方法

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US6828097B1 (en) 2000-05-16 2004-12-07 The Childrens Mercy Hospital Single copy genomic hybridization probes and method of generating same
US7081339B2 (en) * 2002-04-12 2006-07-25 Primera Biosystems, Inc. Methods for variation detection
AU2003275377A1 (en) * 2002-09-30 2004-04-19 The Children's Mercy Hospital Subtelomeric dna probes and method of producing the same
GB0326197D0 (en) * 2003-11-10 2003-12-17 Randox Lab Ltd Molecular marker
AU2005228209A1 (en) * 2004-03-26 2005-10-13 The Children's Mercy Hospital Computational selection of probes for localizing chromosome breakpoints
US8407013B2 (en) 2005-06-07 2013-03-26 Peter K. Rogan AB initio generation of single copy genomic probes
US7734424B1 (en) 2005-06-07 2010-06-08 Rogan Peter K Ab initio generation of single copy genomic probes
US7833713B2 (en) 2005-11-18 2010-11-16 The Children's Mercy Hospital Mitigation of Cot-1 DNA distortion in nucleic acid hybridization
EP2069537B1 (en) 2006-09-01 2011-08-31 Ventana Medical Systems, Inc. Method for producing nucleic acid probes
DK2078197T3 (en) 2006-11-01 2016-05-23 Ventana Med Syst Inc Haptenes, hapten conjugates, compositions thereof and processes for their preparation and use
US7682789B2 (en) 2007-05-04 2010-03-23 Ventana Medical Systems, Inc. Method for quantifying biomolecules conjugated to a nanoparticle
EP3561513A1 (en) 2007-05-23 2019-10-30 Ventana Medical Systems, Inc. Polymeric carriers for immunohistochemistry and in situ hybridization
US8703490B2 (en) 2008-06-05 2014-04-22 Ventana Medical Systems, Inc. Compositions comprising nanomaterials and method for using such compositions for histochemical processes
CN102858996B (zh) * 2009-11-23 2016-01-13 拜尔作物科学股份有限公司 原种事件ee-gm3以及用于鉴定生物样品中的该事件的方法和试剂盒
PT2503873T (pt) 2009-11-23 2017-05-18 Bayer Cropscience Nv Plantas de soja tolerantes a herbicida e métodos para identificar as mesmas
JP5838169B2 (ja) * 2009-12-31 2016-01-06 ヴェンタナ メディカル システムズ， インク． 一意的に特異的核酸プローブを生成するための方法
US20230183780A1 (en) 2016-07-25 2023-06-15 InVivo BioTech Services GmbH Dna probes for in situ hybridization on chromosomes
JP6730525B2 (ja) 2016-11-21 2020-07-29 ナノストリング テクノロジーズ，インコーポレイティド 化学組成物とそれを利用する方法
EP3794146B1 (en) 2018-05-14 2025-12-10 Bruker Spatial Biology, Inc. Method for identifying a predetermined nucleotide sequence
EP3940075A1 (en) * 2020-07-17 2022-01-19 Istituto Nazionale Di Genetica Molecolare-INGM Inhibitors of line1 and uses thereof
CN113483931B (zh) * 2021-07-02 2023-01-24 中国国家铁路集团有限公司 弓网接触力区段异常识别方法及装置

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US5756696A (en) * 1986-01-16 1998-05-26 Regents Of The University Of California Compositions for chromosome-specific staining
WO1999006552A2 (en) * 1997-08-01 1999-02-11 Genset 5' ESTs FOR SECRETED PROTEINS EXPRESSED IN BRAIN

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US5110920A (en) 1982-01-22 1992-05-05 Cetus Corporation HLA typing method and DNA probes used therein
US5985549A (en) 1985-10-22 1999-11-16 University Of Massachusetts Non-isotopic in-situ hybridization method for detection of nucleic acids
US5721098A (en) * 1986-01-16 1998-02-24 The Regents Of The University Of California Comparative genomic hybridization
US5447841A (en) 1986-01-16 1995-09-05 The Regents Of The Univ. Of California Methods for chromosome-specific staining
US5273881A (en) 1990-05-07 1993-12-28 Daikin Industries, Ltd. Diagnostic applications of double D-loop formation
US6040140A (en) * 1991-12-11 2000-03-21 Thomas Jefferson University Methods for screening and treating leukemias resulting from all-1 region chromosome abnormalities
US6121419A (en) * 1992-06-17 2000-09-19 Arch Development Corp. Compositions and methods for detecting gene rearrangements and translocations
JP3509100B2 (ja) * 1993-01-21 2004-03-22 プレジデント アンド フェローズ オブ ハーバード カレッジ 哺乳動物のストレスプロモーターを利用する化合物の毒性測定方法および診断用キット
US6150160A (en) * 1995-11-16 2000-11-21 The John Hopkins University Compositions and methods of use of mammalian retrotransposons
US6828097B1 (en) * 2000-05-16 2004-12-07 The Childrens Mercy Hospital Single copy genomic hybridization probes and method of generating same
WO2002093130A2 (en) * 2001-05-14 2002-11-21 Cancer Genetics, Inc. Methods of analyzing chromosomal translocations using fluorescence in situ hybridization (fish)

Patent Citations (2)

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US5756696A (en) * 1986-01-16 1998-05-26 Regents Of The University Of California Compositions for chromosome-specific staining
WO1999006552A2 (en) * 1997-08-01 1999-02-11 Genset 5' ESTs FOR SECRETED PROTEINS EXPRESSED IN BRAIN

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JPN6011062827; Ｊ．　Ｉｍｍｕｎｏｌ．　Ｍｅｔｈｏｄｓ，　ｖｏｌ．　１６７，　ｐａｇｅｓ　８３-８９　（１９９４） *
JPN6011062829; Ａｎａｌ．　Ｃｈｅｍ．，　ｖｏｌ．　６７，　ｐａｇｅｓ　２６４４-２６４９　（１９９５） *
JPN6011062831; Ａｐｐｌ．　Ｅｎｖｉｒｏｎ．　Ｍｉｃｒｏｂｉｏｌ．，　ｖｏｌ．　５９，　ｐａｇｅｓ　２７９５-２８００　（１９９３） *
JPN6011062833; Ｊ．　Ａｐｐｌ．　Ｂａｃｔｅｒｉｏｌ．，　ｖｏｌ．　８１，　ｐａｇｅｓ　６２６-６３４　（１９９６） *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008534011A (ja) * 2005-03-29 2008-08-28 エグザジェン ダイアグノスティクス インコーポレイテッド ユニーク配列ハイブリダイゼーションプローブ（ｕｓｐ）
JP2010522571A (ja) * 2007-03-28 2010-07-08 ザ チルドレンズ マーシー ホスピタル 少コピー数の核酸セグメントを同定および選択する方法
JP2017533733A (ja) * 2014-11-11 2017-11-16 アボツト・モレキユラー・インコーポレイテツド ハイブリダイゼーションプローブおよび方法

Also Published As

Publication number Publication date
WO2001088089A3 (en) 2002-07-04
AU6461001A (en) 2001-11-26
IL152727A0 (en) 2003-06-24
US20090312533A1 (en) 2009-12-17
CA2409752A1 (en) 2001-11-22
WO2001088089A8 (en) 2005-04-07
WO2001088089A2 (en) 2001-11-22
EP1285093A2 (en) 2003-02-26
EP1285093A4 (en) 2005-10-12
NZ522406A (en) 2006-05-26
NZ539223A (en) 2006-10-27
US20080085509A1 (en) 2008-04-10
AU2001264610B2 (en) 2007-01-04

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