NZ531693A - Method for reducing hypertension and heart failure - Google Patents
Method for reducing hypertension and heart failureInfo
- Publication number
- NZ531693A NZ531693A NZ531693A NZ53169302A NZ531693A NZ 531693 A NZ531693 A NZ 531693A NZ 531693 A NZ531693 A NZ 531693A NZ 53169302 A NZ53169302 A NZ 53169302A NZ 531693 A NZ531693 A NZ 531693A
- Authority
- NZ
- New Zealand
- Prior art keywords
- heart
- set forth
- tyrphostin
- hypertrophy
- hypertension
- Prior art date
Links
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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Applications Claiming Priority (2)
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|---|---|---|---|
| US09/945,192 US6433018B1 (en) | 2001-08-31 | 2001-08-31 | Method for reducing hypertrophy and ischemia |
| PCT/US2002/023444 WO2003020202A2 (en) | 2001-08-31 | 2002-07-23 | Method for reducing hypertension and heart failure |
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| NZ531693A true NZ531693A (en) | 2006-05-26 |
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| NZ531693A NZ531693A (en) | 2001-08-31 | 2002-07-23 | Method for reducing hypertension and heart failure |
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| US (2) | US6433018B1 (OSRAM) |
| EP (1) | EP1427401A4 (OSRAM) |
| JP (2) | JP2005505545A (OSRAM) |
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| AU (1) | AU2002313700B2 (OSRAM) |
| BR (1) | BR0212252A (OSRAM) |
| CA (1) | CA2458798C (OSRAM) |
| MX (1) | MXPA04001913A (OSRAM) |
| NZ (1) | NZ531693A (OSRAM) |
| WO (1) | WO2003020202A2 (OSRAM) |
| ZA (1) | ZA200402540B (OSRAM) |
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| US6433018B1 (en) * | 2001-08-31 | 2002-08-13 | The Research Foundation Of State University Of New York | Method for reducing hypertrophy and ischemia |
| TWI329105B (en) | 2002-02-01 | 2010-08-21 | Rigel Pharmaceuticals Inc | 2,4-pyrimidinediamine compounds and their uses |
| US20050038450A1 (en) * | 2003-06-03 | 2005-02-17 | Ping Hu | Methods and apparatus for minimally invasive transverse aortic banding |
| CN102358738A (zh) | 2003-07-30 | 2012-02-22 | 里格尔药品股份有限公司 | 2,4-嘧啶二胺化合物及其预防和治疗自体免疫疾病的用途 |
| US20050130893A1 (en) * | 2003-09-30 | 2005-06-16 | Joan Smith-Sonneborn | Use of opioids in prevention of and recovery from a stress-induced crash in blood pressure |
| PT1701941E (pt) | 2003-12-11 | 2012-08-03 | Univ Texas | Compostos para o tratamento de doenças proliferativas celulares |
| US7662389B2 (en) * | 2003-12-17 | 2010-02-16 | Alcon, Inc. | Use of serum amyloid A gene in diagnosis and treatment of glaucoma and identification of anti-glaucoma agents |
| TWI398261B (zh) * | 2003-12-17 | 2013-06-11 | Alcon Inc | 血清類澱粉ａ基因於診斷及治療青光眼及鑑定抗青光眼劑上之用途 |
| US20100113481A1 (en) * | 2003-12-17 | 2010-05-06 | Alcon Research, Ltd. | Use of serum amyloid a gene in diagnosis and treatment of glaucoma and identification of anti-glaucoma agents |
| US8691877B2 (en) * | 2004-10-15 | 2014-04-08 | Palo Alto Investors | Methods and compositions for treating a disease condition in a subject |
| EP1904457B1 (en) | 2005-06-08 | 2017-09-06 | Rigel Pharmaceuticals, Inc. | Compositions and methods for inhibition of the jak pathway |
| US20070203161A1 (en) * | 2006-02-24 | 2007-08-30 | Rigel Pharmaceuticals, Inc. | Compositions and methods for inhibition of the jak pathway |
| US10517876B2 (en) | 2005-11-16 | 2019-12-31 | Cti Biopharma Corp. | Oxygen linked pyrimidine derivatives |
| ES2506040T3 (es) | 2005-11-16 | 2014-10-13 | Cti Biopharma Corp. | Derivados de pirimidina ligados a oxígeno |
| CA2637044A1 (en) * | 2006-01-13 | 2007-07-26 | President And Fellows Of Harvard College | Xenohormesis based compositions and methods |
| JP2009528295A (ja) * | 2006-02-24 | 2009-08-06 | ライジェル ファーマシューティカルズ， インコーポレイテッド | Ｊａｋ経路の阻害のための組成物および方法 |
| US8410173B2 (en) * | 2006-02-28 | 2013-04-02 | Ym Biosciences Australia Pty Ltd | Inhibition of JAK2 as a treatment of pulmonary arterial hypertension |
| PL2514742T3 (pl) * | 2006-03-31 | 2015-07-31 | Univ Texas | Leki przeciwnowotworowe będące pochodnymi kwasu kawowego dostępnymi biologicznie po podaniu doustnym |
| US8486941B2 (en) | 2007-03-12 | 2013-07-16 | Ym Biosciences Australia Pty Ltd | Phenyl amino pyrimidine compounds and uses thereof |
| HUE030912T2 (en) | 2008-02-15 | 2017-06-28 | Rigel Pharmaceuticals Inc | Pyrimidine-2-amine compounds and their use as inhibitors of yak kinases |
| MX2010011463A (es) | 2008-04-16 | 2011-06-03 | Portola Pharm Inc | 2,6-diamino-pirimidin-5-il-carboxamidas como inhibidores de syk o jak quinasas. |
| US8138339B2 (en) * | 2008-04-16 | 2012-03-20 | Portola Pharmaceuticals, Inc. | Inhibitors of protein kinases |
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| US10517839B2 (en) * | 2008-06-09 | 2019-12-31 | Cornell University | Mast cell inhibition in diseases of the retina and vitreous |
| JP5675606B2 (ja) | 2008-07-08 | 2015-02-25 | ボード・オブ・リージエンツ，ザ・ユニバーシテイ・オブ・テキサス・システム | シグナル伝達性転写因子（ｓｔａｔ）の増殖及び活性化の新規の抑制剤 |
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| CA2768543C (en) * | 2009-07-28 | 2017-06-20 | Rigel Pharmaceuticals, Inc. | Compositions and methods for inhibition of the jak pathway |
| JP5275966B2 (ja) * | 2009-12-21 | 2013-08-28 | パナソニック株式会社 | 繊維ボードの製造方法 |
| EP2635557A2 (en) | 2010-11-01 | 2013-09-11 | Portola Pharmaceuticals, Inc. | Nicotinamides as jak kinase modulators |
| SG11201402570QA (en) | 2011-11-23 | 2014-06-27 | Portola Pharm Inc | Pyrazine kinase inhibitors |
| US8809359B2 (en) | 2012-06-29 | 2014-08-19 | Ym Biosciences Australia Pty Ltd | Phenyl amino pyrimidine bicyclic compounds and uses thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5138069A (en) * | 1986-07-11 | 1992-08-11 | E. I. Du Pont De Nemours And Company | Angiotensin II receptor blocking imidazoles |
| CA2012634A1 (en) * | 1990-03-20 | 1991-09-20 | Hassan Salari | Tyrphostins for treatment of allergic, inflammatory and cardiovascular diseases |
| US5443836A (en) | 1993-03-15 | 1995-08-22 | Gensia, Inc. | Methods for protecting tissues and organs from ischemic damage |
| US6255296B1 (en) | 1994-01-11 | 2001-07-03 | Endomatrix, Inc. | Composition and method for treating a patient susceptible to or suffering from a cardiovascular disorder or disease |
| IL119069A0 (en) | 1996-08-14 | 1996-11-14 | Mor Research Applic Ltd | Pharmaceutical composition comprising tyrphostins |
| US6358954B1 (en) * | 1999-11-09 | 2002-03-19 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | PDGF receptor kinase inhibitory compounds, their preparation, purification and pharmaceutical compositions including same |
| US6433018B1 (en) * | 2001-08-31 | 2002-08-13 | The Research Foundation Of State University Of New York | Method for reducing hypertrophy and ischemia |
| DE602006000402T8 (de) * | 2006-06-02 | 2009-04-09 | Teva Pharmaceutical Industries Ltd. | Stabile Zubereitung enthaltend eine feuchtigkeitsempfindliche aktive Substanz und Verfahren zur Herstellung der Zubereitung. |
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2001
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2002
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- 2002-07-23 JP JP2003524516A patent/JP2005505545A/ja active Pending
- 2002-07-23 CA CA2458798A patent/CA2458798C/en not_active Expired - Fee Related
- 2002-07-23 MX MXPA04001913A patent/MXPA04001913A/es active IP Right Grant
- 2002-07-23 EP EP02753409A patent/EP1427401A4/en not_active Withdrawn
- 2002-07-23 AU AU2002313700A patent/AU2002313700B2/en not_active Ceased
- 2002-07-23 WO PCT/US2002/023444 patent/WO2003020202A2/en not_active Ceased
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- 2002-07-23 KR KR10-2004-7003111A patent/KR20040050894A/ko not_active Ceased
- 2002-07-23 BR BR0212252-9A patent/BR0212252A/pt not_active IP Right Cessation
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| US6433018B1 (en) | 2002-08-13 |
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| WO2003020202A3 (en) | 2003-08-28 |
| EP1427401A2 (en) | 2004-06-16 |
| JP2005505545A (ja) | 2005-02-24 |
| AU2002313700B2 (en) | 2007-04-26 |
| JP2010285455A (ja) | 2010-12-24 |
| MXPA04001913A (es) | 2004-06-18 |
| CA2458798C (en) | 2013-06-25 |
| WO2003020202A2 (en) | 2003-03-13 |
| US7235588B2 (en) | 2007-06-26 |
| EP1427401A4 (en) | 2009-04-29 |
| KR20040050894A (ko) | 2004-06-17 |
| US20040266661A1 (en) | 2004-12-30 |
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