NZ528394A - Pharmaceutical combinations for the treatment of cancer comprising dioxolane analogues and nuceloside analogues and/or chemotherapeutic agents - Google Patents
Pharmaceutical combinations for the treatment of cancer comprising dioxolane analogues and nuceloside analogues and/or chemotherapeutic agentsInfo
- Publication number
- NZ528394A NZ528394A NZ528394A NZ52839402A NZ528394A NZ 528394 A NZ528394 A NZ 528394A NZ 528394 A NZ528394 A NZ 528394A NZ 52839402 A NZ52839402 A NZ 52839402A NZ 528394 A NZ528394 A NZ 528394A
- Authority
- NZ
- New Zealand
- Prior art keywords
- cancer
- pharmaceutical combination
- combination according
- formula
- compound
- Prior art date
Links
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- 239000000945 filler Substances 0.000 description 1
- 229960000390 fludarabine Drugs 0.000 description 1
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- 210000004185 liver Anatomy 0.000 description 1
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- 210000003593 megakaryocyte Anatomy 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US27797501P | 2001-03-23 | 2001-03-23 | |
| US33060101P | 2001-10-25 | 2001-10-25 | |
| PCT/CA2002/000426 WO2002076472A2 (en) | 2001-03-23 | 2002-03-25 | Pharmaceutical combinations for the treatment of cancer comprising dioxolane nucleoside analogs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ528394A true NZ528394A (en) | 2005-06-24 |
Family
ID=26958821
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ528394A NZ528394A (en) | 2001-03-23 | 2002-03-25 | Pharmaceutical combinations for the treatment of cancer comprising dioxolane analogues and nuceloside analogues and/or chemotherapeutic agents |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US6800639B2 (enExample) |
| EP (1) | EP1370270B1 (enExample) |
| JP (1) | JP4391087B2 (enExample) |
| KR (1) | KR20040018341A (enExample) |
| AT (1) | ATE450265T1 (enExample) |
| CA (1) | CA2441568A1 (enExample) |
| DE (1) | DE60234577D1 (enExample) |
| HU (1) | HUP0400314A3 (enExample) |
| MX (1) | MXPA03008623A (enExample) |
| NO (1) | NO20034204L (enExample) |
| NZ (1) | NZ528394A (enExample) |
| PL (1) | PL365285A1 (enExample) |
| WO (1) | WO2002076472A2 (enExample) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20080075762A1 (en) * | 2001-10-03 | 2008-03-27 | Paul Tardi | Compositions for delivery of drug combinations |
| US7850990B2 (en) * | 2001-10-03 | 2010-12-14 | Celator Pharmaceuticals, Inc. | Compositions for delivery of drug combinations |
| CA2383259A1 (en) | 2002-04-23 | 2003-10-23 | Celator Technologies Inc. | Synergistic compositions |
| UA82322C2 (uk) * | 2002-07-30 | 2008-04-10 | Центаріс Гмбх | Застосування алкілфосфохолінів в комбінації з протипухлинними лікарськими засобами |
| US8383605B2 (en) * | 2002-07-30 | 2013-02-26 | Aeterna Zentaris Gmbh | Use of alkylphosphocholines in combination with antimetabolites for the treatment of benign and malignant oncoses in humans and mammals |
| US20040192652A1 (en) * | 2002-12-06 | 2004-09-30 | Giles Francis J. | Pharmaceutical combinations and methods for the treatment of leukemia |
| EP1617828A2 (en) * | 2003-04-02 | 2006-01-25 | Celator Pharmaceuticals, Inc. | Nano-sized vehicles transporting a therapeutic agent and at least one drug resistance modulator for the treatment of multi drug resistance |
| PL2368554T3 (pl) | 2003-04-08 | 2015-05-29 | Progenics Pharm Inc | Preparaty farmaceutyczne zawierające metylonaltrekson |
| US20040248915A1 (en) * | 2003-04-25 | 2004-12-09 | Jacques Jolivet | Method for administration of troxacitabine |
| DE602004027824D1 (de) * | 2003-09-25 | 2010-08-05 | Astellas Pharma Inc | Antitumorales mittel mit einem histon-deacetylase-hemmer und einem topoisomerase-ii-hemmer |
| MX2007010833A (es) | 2005-03-07 | 2009-02-17 | Univ Chicago | Uso de antagonistas opioides para atenuar proliferacion y migracion de células endoteliales. |
| US8524731B2 (en) | 2005-03-07 | 2013-09-03 | The University Of Chicago | Use of opioid antagonists to attenuate endothelial cell proliferation and migration |
| US8518962B2 (en) | 2005-03-07 | 2013-08-27 | The University Of Chicago | Use of opioid antagonists |
| US9662325B2 (en) | 2005-03-07 | 2017-05-30 | The University Of Chicago | Use of opioid antagonists to attenuate endothelial cell proliferation and migration |
| AR057325A1 (es) | 2005-05-25 | 2007-11-28 | Progenics Pharm Inc | Sintesis de (s)-n-metilnaltrexona, composiciones farmaceuticas y usos |
| AR057035A1 (es) | 2005-05-25 | 2007-11-14 | Progenics Pharm Inc | SíNTESIS DE (R)-N-METILNALTREXONA, COMPOSICIONES FARMACÉUTICAS Y USOS |
| US8481505B2 (en) | 2005-09-12 | 2013-07-09 | The Ohio State University Research Foundation | Compositions and methods for the diagnosis and therapy of BCL2-associated cancers |
| TWI489984B (zh) | 2006-08-04 | 2015-07-01 | Wyeth Corp | 用於非經腸道傳輸化合物之配方及其用途 |
| WO2008030373A2 (en) * | 2006-09-01 | 2008-03-13 | University Of Georgia Research Foundation, Inc. | L- oddc prodrugs for cancer |
| MX2009010550A (es) | 2007-03-29 | 2009-12-14 | Progenics Pharm Inc | Formas de cristal de bromuro de (r)-n-metilnaltrexona y uso de las mismas. |
| WO2008121348A2 (en) | 2007-03-29 | 2008-10-09 | Progenics Pharmaceuticals, Inc. | Peripheral opioid receptor antagonists and uses thereof |
| JP5469593B2 (ja) | 2007-03-29 | 2014-04-16 | ワイス・エルエルシー | 末梢性オピオイド受容体アンタゴニストおよびその使用 |
| US20090048205A1 (en) * | 2007-08-15 | 2009-02-19 | Colin Meyer | Combination therapy with synthetic triterpenoids and gemcitabine |
| ME03529B (me) | 2008-01-11 | 2020-04-20 | Reata Pharmaceuticals Inc | Sintetički triterpenoidi i metode njihove upotrebe u tretmanu bolesti |
| AU2008349873B2 (en) | 2008-02-06 | 2014-02-13 | Progenics Pharmaceuticals, Inc. | Preparation and use of (R),(R)-2,2'-bis-methylnaltrexone |
| CA2719134C (en) | 2008-03-21 | 2015-06-30 | The University Of Chicago | Treatment with opioid antagonists and mtor inhibitors |
| US20100004193A1 (en) * | 2008-07-07 | 2010-01-07 | Fondazione Per La Ricerca Biomedica Avanzata Onlus - Istituto Veneto Di Medicina Molecolare | Combination therapy |
| CA2676881C (en) | 2008-09-30 | 2017-04-25 | Wyeth | Peripheral opioid receptor antagonists and uses thereof |
| US8383607B2 (en) | 2010-03-31 | 2013-02-26 | Aeterna Zentaris Gmbh | Perifosine and capecitabine as a combined treatment for cancer |
| AU2011240690C1 (en) * | 2010-04-12 | 2014-11-06 | Reata Pharmaceuticals Holdings, LLC | Method of treating obesity using antioxidant inflammation modulators |
| WO2014025961A1 (en) * | 2012-08-10 | 2014-02-13 | Analiza, Inc. | Methods and devices for analyzing species to determine diseases |
| JP7337539B2 (ja) * | 2018-06-21 | 2023-09-04 | メディヴィル・アクチエボラーグ | 白血病療法のための塩基修飾シチジンヌクレオチド |
| CN118511077A (zh) | 2021-10-28 | 2024-08-16 | 克利夫兰诊断有限公司 | 用于确定多种类型的癌症的分配系统和方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5270315A (en) | 1988-04-11 | 1993-12-14 | Biochem Pharma Inc. | 4-(purinyl bases)-substituted-1,3-dioxlanes |
| US5041449A (en) | 1988-04-11 | 1991-08-20 | Iaf Biochem International, Inc. | 4-(nucleoside base)-substituted-1,3-dioxolanes useful for treatment of retroviral infections |
| US6350753B1 (en) | 1988-04-11 | 2002-02-26 | Biochem Pharma Inc. | 2-Substituted-4-substituted-1,3-dioxolanes and use thereof |
| WO1992018517A1 (en) | 1991-04-17 | 1992-10-29 | Yale University | Method of treating or preventing hepatitis b virus |
| US5817667A (en) | 1991-04-17 | 1998-10-06 | University Of Georgia Research Foudation | Compounds and methods for the treatment of cancer |
| IL115156A (en) * | 1994-09-06 | 2000-07-16 | Univ Georgia | Pharmaceutical compositions for the treatment of cancer comprising 1-(2-hydroxymethyl-1,3-dioxolan-4-yl) cytosines |
| DE60042921D1 (de) * | 1999-03-29 | 2009-10-22 | Shire Canada Inc | Verwendung von cytidinderivaten zur behandlung von leukämie |
| CN100376570C (zh) * | 2000-10-13 | 2008-03-26 | 希拉生物化学股份有限公司 | 改善胞间传输的二氧戊环类似物 |
| US20040248915A1 (en) * | 2003-04-25 | 2004-12-09 | Jacques Jolivet | Method for administration of troxacitabine |
-
2002
- 2002-03-25 AT AT02713967T patent/ATE450265T1/de not_active IP Right Cessation
- 2002-03-25 DE DE60234577T patent/DE60234577D1/de not_active Expired - Lifetime
- 2002-03-25 JP JP2002574985A patent/JP4391087B2/ja not_active Expired - Fee Related
- 2002-03-25 MX MXPA03008623A patent/MXPA03008623A/es active IP Right Grant
- 2002-03-25 WO PCT/CA2002/000426 patent/WO2002076472A2/en not_active Ceased
- 2002-03-25 NZ NZ528394A patent/NZ528394A/en not_active IP Right Cessation
- 2002-03-25 EP EP02713967A patent/EP1370270B1/en not_active Expired - Lifetime
- 2002-03-25 US US10/104,067 patent/US6800639B2/en not_active Expired - Lifetime
- 2002-03-25 PL PL02365285A patent/PL365285A1/xx unknown
- 2002-03-25 HU HU0400314A patent/HUP0400314A3/hu unknown
- 2002-03-25 KR KR10-2003-7012324A patent/KR20040018341A/ko not_active Withdrawn
- 2002-03-25 CA CA002441568A patent/CA2441568A1/en not_active Abandoned
-
2003
- 2003-09-22 NO NO20034204A patent/NO20034204L/no not_active Application Discontinuation
-
2004
- 2004-05-26 US US10/853,241 patent/US20050004081A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CA2441568A1 (en) | 2002-10-03 |
| JP2004525142A (ja) | 2004-08-19 |
| US20050004081A1 (en) | 2005-01-06 |
| US20030083316A1 (en) | 2003-05-01 |
| WO2002076472A3 (en) | 2003-04-10 |
| NO20034204D0 (no) | 2003-09-22 |
| ATE450265T1 (de) | 2009-12-15 |
| HUP0400314A3 (en) | 2006-02-28 |
| WO2002076472A2 (en) | 2002-10-03 |
| HUP0400314A2 (hu) | 2004-08-30 |
| US6800639B2 (en) | 2004-10-05 |
| EP1370270A2 (en) | 2003-12-17 |
| MXPA03008623A (es) | 2004-05-21 |
| EP1370270B1 (en) | 2009-12-02 |
| NO20034204L (no) | 2003-11-21 |
| JP4391087B2 (ja) | 2009-12-24 |
| KR20040018341A (ko) | 2004-03-03 |
| DE60234577D1 (de) | 2010-01-14 |
| PL365285A1 (en) | 2004-12-27 |
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