NZ528322A - Proanthocyanidins for the treatment of amyloid and alpha-synuclein diseases such as alzheimer's disease and parkinson's - Google Patents
Proanthocyanidins for the treatment of amyloid and alpha-synuclein diseases such as alzheimer's disease and parkinson'sInfo
- Publication number
- NZ528322A NZ528322A NZ528322A NZ52832202A NZ528322A NZ 528322 A NZ528322 A NZ 528322A NZ 528322 A NZ528322 A NZ 528322A NZ 52832202 A NZ52832202 A NZ 52832202A NZ 528322 A NZ528322 A NZ 528322A
- Authority
- NZ
- New Zealand
- Prior art keywords
- epicatechin
- proanthocyanidin
- amyloid
- formula
- proanthocyanidins
- Prior art date
Links
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Oncology (AREA)
- Endocrinology (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrane Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US27686601P | 2001-03-15 | 2001-03-15 | |
| US09/938,987 US6607758B2 (en) | 1997-05-15 | 2001-08-24 | Methods for inhibiting and reducing amyloid fibril formation associated with Alzheimer's Disease and other amyloidoses |
| US10/053,625 US6929808B2 (en) | 2000-11-03 | 2001-11-02 | Methods of isolating amyloid-inhibiting compounds and use of compounds isolated from Uncaria tomentosa and related plants |
| PCT/US2001/051131 WO2002042429A2 (en) | 2000-11-03 | 2001-11-02 | Methods of isolating amyloid-inhibiting compounds and use of compounds isolated from uncaria tomentosa and related plants |
| US33872101P | 2001-12-04 | 2001-12-04 | |
| US33903301P | 2001-12-10 | 2001-12-10 | |
| US33896901P | 2001-12-10 | 2001-12-10 | |
| PCT/US2002/004764 WO2002076381A2 (en) | 2001-03-15 | 2002-02-15 | Proanthocyanidins for the treatment of amyloid and alpha-synuclein diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ528322A true NZ528322A (en) | 2005-03-24 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ528322A NZ528322A (en) | 2001-03-15 | 2002-02-15 | Proanthocyanidins for the treatment of amyloid and alpha-synuclein diseases such as alzheimer's disease and parkinson's |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP1377287A4 (enExample) |
| JP (1) | JP4380991B2 (enExample) |
| AU (1) | AU2002250117B2 (enExample) |
| CA (1) | CA2441099C (enExample) |
| NZ (1) | NZ528322A (enExample) |
| WO (1) | WO2002076381A2 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070208087A1 (en) | 2001-11-02 | 2007-09-06 | Sanders Virginia J | Compounds, compositions and methods for the treatment of inflammatory diseases |
| US7514107B2 (en) | 2002-03-21 | 2009-04-07 | Mars, Incorporated | Treatment of diseases involving defective gap junctional communication |
| PT1511710E (pt) * | 2002-05-31 | 2014-02-26 | Proteotech Inc | Compostos, composições e métodos para o tratamento de doenças da amiloide e sinucleínopatias tais como doença de alzheimer, diabetes do tipo 2, e doença de parkinson |
| CA2499549C (en) * | 2002-10-11 | 2012-01-24 | Proteotech, Inc. | Isolation, purification and synthesis of procyanidin b2 and uses thereof |
| JP2006232670A (ja) * | 2003-05-20 | 2006-09-07 | Ajinomoto Co Inc | 神経障害用薬剤 |
| WO2005082351A1 (ja) * | 2004-03-02 | 2005-09-09 | Eisai R & D Management Co., Ltd. | 神経変性疾患治療剤 |
| DK2004155T3 (en) * | 2006-03-29 | 2018-04-30 | Wista Lab Ltd | PROTEIN AGGREGATION INHIBITORS |
| WO2009104556A1 (ja) * | 2008-02-19 | 2009-08-27 | 株式会社岐阜セラツク製造所 | 組成物 |
| JP5738755B2 (ja) * | 2008-05-09 | 2015-06-24 | アイカーン スクール オブ メディシン アット マウント シナイ | 神経変性疾患を予防および治療するための方法 |
| US20140179774A1 (en) * | 2012-12-26 | 2014-06-26 | Industrial Technology Research Institute | Methods for inhibition of shc-1/p66 to combat aging-related diseases |
| CN107530385A (zh) | 2015-05-11 | 2018-01-02 | 株式会社明治 | 用于促进脑源性神经营养因子产生的组合物 |
| KR102441381B1 (ko) * | 2016-07-18 | 2022-09-07 | (주)아모레퍼시픽 | 3-O-갈로일-3,3',5,5',7-펜타하이드록시플라반(3-O-galloyl-3,3',5,5',7- pentahydroxyflavan)을 포함하는 인지 기능 개선용 조성물 |
| WO2021193703A1 (ja) * | 2020-03-24 | 2021-09-30 | 学校法人 芝浦工業大学 | 中枢神経賦活組成物 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4698360B1 (en) * | 1985-04-09 | 1997-11-04 | D Investigations Pharmacologiq | Plant extract with a proanthocyanidins content as therapeutic agent having radical scavenger effect and use thereof |
| US6346280B1 (en) * | 1997-05-15 | 2002-02-12 | University Of Washington | Composition and methods for inhibiting the formation of brain amyloid deposits |
| WO1998051302A1 (en) * | 1997-05-15 | 1998-11-19 | University Of Washington | Composition and methods for treating alzheimer's disease and other amyloidoses |
| US5922756A (en) * | 1998-02-14 | 1999-07-13 | Chan; Marion Man-Ying | Method of inhibiting nitric oxide synthase |
| CA2322860C (en) * | 1998-03-12 | 2010-10-19 | Mars, Incorporated | Products containing polyphenol(s) and l-arginine to stimulate nitric oxide production |
| AU3886200A (en) * | 1999-03-15 | 2000-10-16 | Proteotech, Inc. | Methods of treating alzheimer's disease and other amyloidoses using hypericum perforatum and derivatives thereof |
| EP1246632A4 (en) * | 1999-12-30 | 2004-08-18 | Proteotech Inc | CATECHINE AND GREEN TEA EXTRACT FOR TREATING AMYLOIDOSES IN GENERAL OR. AT ALZHEIMER |
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2002
- 2002-02-15 AU AU2002250117A patent/AU2002250117B2/en not_active Ceased
- 2002-02-15 EP EP02719009A patent/EP1377287A4/en not_active Withdrawn
- 2002-02-15 CA CA2441099A patent/CA2441099C/en not_active Expired - Fee Related
- 2002-02-15 WO PCT/US2002/004764 patent/WO2002076381A2/en not_active Ceased
- 2002-02-15 NZ NZ528322A patent/NZ528322A/en not_active IP Right Cessation
- 2002-02-15 JP JP2002574897A patent/JP4380991B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2441099A1 (en) | 2002-10-03 |
| CA2441099C (en) | 2011-04-19 |
| JP4380991B2 (ja) | 2009-12-09 |
| EP1377287A2 (en) | 2004-01-07 |
| WO2002076381A3 (en) | 2002-11-21 |
| WO2002076381A2 (en) | 2002-10-03 |
| AU2002250117B8 (en) | 2002-10-08 |
| AU2002250117B2 (en) | 2007-11-29 |
| EP1377287A4 (en) | 2007-11-14 |
| JP2005505497A (ja) | 2005-02-24 |
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