NZ500216A - Beta-amyloid peptide-binding proteins and pharmaceutical use - Google Patents
Beta-amyloid peptide-binding proteins and pharmaceutical useInfo
- Publication number
- NZ500216A NZ500216A NZ500216A NZ50021698A NZ500216A NZ 500216 A NZ500216 A NZ 500216A NZ 500216 A NZ500216 A NZ 500216A NZ 50021698 A NZ50021698 A NZ 50021698A NZ 500216 A NZ500216 A NZ 500216A
- Authority
- NZ
- New Zealand
- Prior art keywords
- amyloid peptide
- beta
- binding proteins
- pharmaceutical use
- proteins
- Prior art date
Links
- 101000638018 Homo sapiens TM2 domain-containing protein 1 Proteins 0.000 title 1
- 102100032067 TM2 domain-containing protein 1 Human genes 0.000 title 1
- DZHSAHHDTRWUTF-SIQRNXPUSA-N amyloid-beta polypeptide 42 Chemical compound C([C@@H](C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)NCC(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(O)=O)[C@@H](C)CC)C(C)C)NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC=1N=CNC=1)NC(=O)[C@H](CC=1N=CNC=1)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC=1N=CNC=1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)CC(O)=O)C(C)C)C(C)C)C1=CC=CC=C1 DZHSAHHDTRWUTF-SIQRNXPUSA-N 0.000 abstract 2
- 102000040430 polynucleotide Human genes 0.000 abstract 2
- 108091033319 polynucleotide Proteins 0.000 abstract 2
- 239000002157 polynucleotide Substances 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 230000001594 aberrant effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Toxicology (AREA)
- Neurosurgery (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Zoology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6458397P | 1997-04-16 | 1997-04-16 | |
| PCT/US1998/007462 WO1998046636A2 (en) | 1997-04-16 | 1998-04-14 | β-AMYLOID PEPTIDE-BINDING PROTEINS AND POLYNUCLEOTIDES ENCODING THE SAME |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ500216A true NZ500216A (en) | 2001-06-29 |
Family
ID=22056941
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ500216A NZ500216A (en) | 1997-04-16 | 1998-04-14 | Beta-amyloid peptide-binding proteins and pharmaceutical use |
Country Status (18)
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000022125A2 (en) * | 1998-10-13 | 2000-04-20 | American Home Products Corporation | 6-protein-coupled receptor-like proteins, polynucleotides encoded by them, and methods of using same |
| US6787319B2 (en) | 1997-04-16 | 2004-09-07 | American Home Products Corp. | β-amyloid peptide-binding proteins and polynucleotides encoding the same |
| US7005295B1 (en) | 1997-04-16 | 2006-02-28 | Wyeth | β-amyloid peptide-binding proteins and polynucleotides encoding the same |
| US6455082B1 (en) * | 1999-04-26 | 2002-09-24 | Nestec S.A. | Shelf-stable calcium fortified milk and dairy products |
| CA2387646A1 (en) * | 1999-10-21 | 2001-04-26 | Kalobios, Inc. | A general method for optimizing the expression of heterologous proteins |
| US8663650B2 (en) | 2003-02-21 | 2014-03-04 | Ac Immune Sa | Methods and compositions comprising supramolecular constructs |
| US7807171B2 (en) | 2003-07-25 | 2010-10-05 | Ac Immune Sa | Therapeutic vaccine targeted against P-glycoprotein 170 for inhibiting multidrug resistance in the treatment of cancers |
| WO2012020124A1 (en) | 2010-08-12 | 2012-02-16 | Ac Immune S.A. | Vaccine engineering |
| CN103189050B (zh) | 2010-10-26 | 2017-09-29 | Ac免疫有限公司 | 包含通过疏水部分修饰的肽的基于脂质体的构建体 |
| CN102060912B (zh) * | 2010-11-22 | 2012-11-14 | 清华大学 | 淀粉样蛋白寡聚体构象型抗原表位多肽及其应用 |
| CN111320678B (zh) * | 2020-03-09 | 2023-06-09 | 安亭生物有限责任公司 | 抗菌肽突变体及其应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0332640A1 (en) * | 1986-11-17 | 1989-09-20 | California Biotechnology, Inc. | Recombinant alzheimer's amyloid protein |
| IL115743A0 (en) * | 1994-10-28 | 1996-01-19 | American Nat Red Cross | A mammal with cells containing a transgene and its production |
| US5786180A (en) * | 1995-02-14 | 1998-07-28 | Bayer Corporation | Monoclonal antibody 369.2B specific for β A4 peptide |
-
1998
- 1998-04-14 CA CA002286484A patent/CA2286484A1/en not_active Abandoned
- 1998-04-14 EA EA199900941A patent/EA004256B1/ru not_active IP Right Cessation
- 1998-04-14 EP EP98918186A patent/EP0975753A2/en not_active Withdrawn
- 1998-04-14 BR BR9808562-0A patent/BR9808562A/pt not_active Application Discontinuation
- 1998-04-14 WO PCT/US1998/007462 patent/WO1998046636A2/en active Application Filing
- 1998-04-14 KR KR1019997009480A patent/KR20010006393A/ko not_active Ceased
- 1998-04-14 GE GE3744A patent/GEP20043386B/en unknown
- 1998-04-14 EE EEP199900482A patent/EE9900482A/xx unknown
- 1998-04-14 JP JP54419698A patent/JP2001523093A/ja active Pending
- 1998-04-14 NZ NZ500216A patent/NZ500216A/xx unknown
- 1998-04-14 CN CNB988043173A patent/CN1196785C/zh not_active Expired - Fee Related
- 1998-04-14 AU AU71156/98A patent/AU740445B2/en not_active Ceased
- 1998-04-14 UA UA99116193A patent/UA72875C2/uk unknown
- 1998-04-14 SK SK1432-99A patent/SK143299A3/sk unknown
- 1998-04-14 HU HU0003116A patent/HUP0003116A3/hu unknown
- 1998-04-14 CN CNA200510052975XA patent/CN1690203A/zh active Pending
- 1998-04-14 IL IL13223698A patent/IL132236A0/xx active IP Right Grant
- 1998-04-14 ID IDW991187D patent/ID24914A/id unknown
-
1999
- 1999-10-06 IL IL132236A patent/IL132236A/en not_active IP Right Cessation
- 1999-10-15 NO NO995062A patent/NO995062L/no not_active Application Discontinuation
-
2006
- 2006-11-05 IL IL179047A patent/IL179047A0/en unknown
-
2007
- 2007-12-28 JP JP2007339660A patent/JP2008104465A/ja active Pending
-
2008
- 2008-06-18 JP JP2008159606A patent/JP2008253275A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CN1196785C (zh) | 2005-04-13 |
| IL132236A (en) | 2007-03-08 |
| NO995062L (no) | 1999-12-14 |
| IL132236A0 (en) | 2001-03-19 |
| CA2286484A1 (en) | 1998-10-22 |
| GEP20043386B (en) | 2004-02-10 |
| EA199900941A1 (ru) | 2000-06-26 |
| WO1998046636A3 (en) | 1999-01-28 |
| EP0975753A2 (en) | 2000-02-02 |
| EA004256B1 (ru) | 2004-02-26 |
| IL179047A0 (en) | 2007-03-08 |
| JP2008253275A (ja) | 2008-10-23 |
| HUP0003116A2 (hu) | 2001-01-29 |
| ID24914A (id) | 2000-08-31 |
| WO1998046636A2 (en) | 1998-10-22 |
| NO995062D0 (no) | 1999-10-15 |
| SK143299A3 (en) | 2000-09-12 |
| JP2008104465A (ja) | 2008-05-08 |
| UA72875C2 (uk) | 2005-05-16 |
| HUP0003116A3 (en) | 2003-03-28 |
| BR9808562A (pt) | 2000-05-23 |
| KR20010006393A (ko) | 2001-01-26 |
| CN1268973A (zh) | 2000-10-04 |
| AU7115698A (en) | 1998-11-11 |
| EE9900482A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 2000-06-15 |
| JP2001523093A (ja) | 2001-11-20 |
| AU740445B2 (en) | 2001-11-01 |
| CN1690203A (zh) | 2005-11-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PSEA | Patent sealed | ||
| RENW | Renewal (renewal fees accepted) | ||
| RENW | Renewal (renewal fees accepted) | ||
| RENW | Renewal (renewal fees accepted) |